Effects of tyroserleutide on phosphatidylinositol 3′-kinase/AKT pathway in human hepatocellular carcinoma cell

Journal of Drug Targeting

Volumn 22, Issue 2, 2014, Pages 146-155

  Fu, Zheng ^a   Ren, Li ^a   Wei, Huiting ^a   Lv, Junqiang ^a   Che, Xuchun ^a   Zhu, Zhifeng ^a   Jia, Jing ^a   Wang, Li ^a   Lin, Gang ^b   Lu, Rong ^a,b   Yao, Zhi ^a  

^a TIANJIN MEDICAL UNIVERSITY   (China)

^b Shenzhen Kangzhe Pharmaceutical Co Ltd   (China)

Author keywords

Drug targeting; Hepatocellular carcinoma; PI3K AKT signal pathway; Tyroserleutide

Indexed keywords

ANTINEOPLASTIC AGENT; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN MDM2; PROTEIN P53; TYROSERLEUTIDE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL DEATH; CELL PROLIFERATION; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INACTIVATION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; INHIBITION KINETICS; LIVER CELL CARCINOMA; MITOCHONDRION; ONCOGENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TUMOR CELL; UPREGULATION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CELL CYCLE; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL PROLIFERATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; OLIGOPEPTIDES; PHOSPHATIDYLINOSITOL 3-KINASE; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; RNA, MESSENGER; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84891750949     PISSN: 1061186X     EISSN: 10292330     Source Type: Journal    
DOI: 10.3109/1061186X.2013.844820     Document Type: Article

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