Experimental study of the inhibition of human hepatocarcinoma Bel7402 cells by the tripeptide tyroserleutide(YSL)

Cancer Chemotherapy and Pharmacology

Volumn 57, Issue 2, 2006, Pages 248-256

  Lu, Rong ^a,b   Jia, Jing ^a   Bao, Leyuan ^a   Fu, Zheng ^a   Li, Guoli ^a   Wang, Song ^a   Wang, Zhuo ^a   Jin, Mengjue ^a   Gao, Wenyuan ^c   Yao, Zhi ^a,c  

^a TIANJIN MEDICAL UNIVERSITY   (China)

^b Shenzhen Kangzhe Pharmaceutical Co Ltd   (China)

^c TIANJIN UNIVERSITY   (China)

Author keywords

Antitumor; Apoptosis; Hepatocarcinoma Bel7402; MTT; Tyroserleutide; YSL

Indexed keywords

AMINO ACID; CYCLINE; DNA NUCLEOTIDYLEXOTRANSFERASE; NITROBLUE TETRAZOLIUM; SODIUM CHLORIDE; TRIPEPTIDE; TYROSYLSERYLLEUCINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CANCER TRANSPLANTATION; CARCINOMA CELL; CELL CYCLE; CELL PROLIFERATION; CELL ULTRASTRUCTURE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG SCREENING; ELECTRON MICROSCOPY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL CARCINOMA; MALE; MITOSIS INHIBITION; MOUSE; NICK END LABELING; NITROBLUE TETRAZOLIUM TEST; NONHUMAN; PRIORITY JOURNAL; TUMOR CELL; TUMOR GROWTH; TUMOR NECROSIS; TUMOR VOLUME; TUMOR XENOGRAFT;

ANIMALS; APOPTOSIS; CARCINOMA; CELL PROLIFERATION; HUMANS; LIVER NEOPLASMS; MALE; MICE; MICE, NUDE; NECROSIS; OLIGOPEPTIDES; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED;

EID: 28844435394     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-005-0046-z     Document Type: Article

References (20)

1. Dwyer JM (1996) Transfer factor in the age of molecular biology: a review. Biotherapy 9:7-11
2. Berressem Peter (1991) Application of glycopeptide fractions in the treatment of tumor patients suffering from immunodeficiency. Therapeutikon 5:264-270
3. Wang C, Ding W, Zhao M, Lin G, Peng S (2003) Studies on the large scale synthesis and anti-tumor activity of YSL. Prep Biochem Biotechnol 33:189-195
4. Ding W, Zhang J, Yao Z, Lu R, Wu D, Li G et al (2004) The synthesis, distribution, and anti-hepatic cancer activity of YSL. Bioorg Med Chem 12:4989-4994
5. Li Y, Tang ZY, Wang L, Yao Z, Lu R, Xue Q et al (2004) The inhibitory of tripeptide CMS024 on the metastasis of human hepatocarcinoma in nude mice. J Chin Med 84:675-679
6. Xu SY, Bian RL, Chen X (2002) Methodology of pharmacological experiment (3rd edn). People's Health Publishing House pp 1785-1786
7. Han Y (1997) The research and experiment techniques of anticarcinoma drugs (1st edn). Beijing medical university and China Xiehe medical university united Publishing House p 299
8. Roger JB (1996) Cancer Biology (2nd edn). King Pearson Education Limited: 199
9. Schwartzman RA, Cidlowski JA (1993) Apoptosis: the biochemistry and molecular biology of programmed cell death. Endocrine Rev 14:133
10. Vermes I, Haanen C (1994) Apoptosis and programmed cell death in health and disease. Adv Clin Chem 31:177
11. Xu KL (1997) The review of the abnormal modulation of apoptosis gene in the occurrence and development of tumor and lung cancer. J Cancer Chin 7:4
12. Lowe SW, Lin AW (2000) Apotosis in cancer. Carcinogenesis 21:485-495
13. Chabner BA (1982) The role of drugs in cancer treatment. In: Chabner B (ed) Pharmacologic principles of cancer treatment. Saunders, Philadelphia, pp 1-14
14. Chen ruiming, Zhu dehou, Ye xiuzhen (1975) The establishment and character of human hepacarcimoma cell line (BEL-7402) in vitro. Comm Sci 20:434-436
15. Wright WE, Shay JW (2001) Cellular senescence as a tumor-protection mechanism: the essential role of counting. Curr Opin Genet Dev 11:98-103
16. Roninson IB, Broude EV, Chang BD (2001) If not apoptosis, then what treatment-induced senescence and mitotic catastrophe in tumor cells. Drug Resist Updat 4:303-313
17. Kerr JF, Wyllie AH, Currie AR (1972) Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26:239-247
18. Marcel L, Simone K, Barbara S (1998) Differentiation between apoptotic and necrotic cell death by means of the bm cell death detection elisa or annexin V staining. Biochemicano 2
19. Darzynkiewicz Z, Li X, Gong J (1994) Assays of cell viability: discrimination of cells dying by apoptosis. Methods Cell Biol 41:15-38
20. McDonnell TJ, Meyn RE, Robertson LE (1995) Implications of apoptotic cell death regulation in cancer therapy. Semin Cancer Biol 6:53-60