Propranolol prevents life-threatening arrhythmias in LQT3 transgenic mice: Implications for the clinical management of LQT3 patients

Heart Rhythm

Volumn 11, Issue 1, 2014, Pages 126-132

  Calvillo, Laura ^a   Spazzolini, Carla ^b   Vullo, Eleonora ^b,c   Insolia, Roberto ^c   Crotti, Lia ^a,c,d   Schwartz, Peter J ^a,c,e,f,g  

^a ISTITUTO AUXOLOGICO ITALIANO   (Italy)

^b FONDAZIONE IRCCS POLICLINICO SAN MATTEO   (Italy)

^c UNIVERSITY OF PAVIA   (Italy)

^d INSTITUTE OF EPIDEMIOLOGY   (Germany)

^e UNIVERSITY OF CAPE TOWN   (South Africa)

^f STELLENBOSCH UNIVERSITY   (South Africa)

^g KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

Beta blocker; Long QT syndrome type 3; Sudden death; Transgenic mice

Indexed keywords

CARBACHOL; PROPRANOLOL; SODIUM CHANNEL NAV1.5; BETA ADRENERGIC RECEPTOR BLOCKING AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIARRHYTHMIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; HEART ARRHYTHMIA; HEART RATE; HEART VENTRICLE FIBRILLATION; HEART VENTRICLE TACHYCARDIA; LIFE THREATENING ARRHYTHMIA; LONG QT SYNDROME 3; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; QT INTERVAL; TRANSGENIC MOUSE; WILD TYPE; ANIMAL; COMPLICATION; DEATH, SUDDEN, CARDIAC; DISEASE MODEL; DRUG EFFECTS; ELECTROCARDIOGRAPHY; HEART MUSCLE CONDUCTION SYSTEM; HUMAN; INTRAPERITONEAL DRUG ADMINISTRATION; LONG QT SYNDROME; PATHOPHYSIOLOGY; TREATMENT OUTCOME;

ADRENERGIC BETA-ANTAGONISTS; ANIMALS; DEATH, SUDDEN, CARDIAC; DISEASE MODELS, ANIMAL; ELECTROCARDIOGRAPHY; HEART CONDUCTION SYSTEM; HUMANS; INJECTIONS, INTRAPERITONEAL; LONG QT SYNDROME; MICE; MICE, TRANSGENIC; PROPRANOLOL; TREATMENT OUTCOME;

EID: 84891704985     PISSN: 15475271     EISSN: 15563871     Source Type: Journal    
DOI: 10.1016/j.hrthm.2013.10.029     Document Type: Article

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