The promoter of miR-663 is hypermethylated in Chinese pediatric acute myeloid leukemia (AML)

BMC Medical Genetics

Volumn 14, Issue 1, 2013, Pages

  Yan Fang, Tao ^a   Jian, Ni ^b   Jun, Lu ^a   Na, Wang ^a   Pei Fang, Xiao ^a   Wen Li, Zhao ^a   Dong, Wu ^a   Li, Pang ^a   Jian, Wang ^a   Xing, Feng ^a   Jian, Pan ^a,b  

^a CHILDREN S HOSPITAL OF SOOCHOW UNIVERSITY   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Acute myeloid leukemia; Hypermethylation; MiR 663; Pediatric

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; MICRORNA; MICRORNA 663; REAGENT; UNCLASSIFIED DRUG; UNTRANSLATED RNA;

ACUTE GRANULOCYTIC LEUKEMIA; ARTICLE; BONE MARROW; CANCER CELL CULTURE; CHILD; CHILDHOOD LEUKEMIA; CLINICAL ARTICLE; CLINICAL FEATURE; DNA METHYLATION; FEMALE; GENE SEQUENCE; HUMAN; HUMAN TISSUE; MALE; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; PROMOTER REGION; PROTEIN EXPRESSION; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SCHOOL CHILD; TRANSCRIPTION INITIATION;

ADOLESCENT; AZACITIDINE; BONE MARROW; CELL LINE, TUMOR; CHILD; CHILD, PRESCHOOL; CHINA; DNA METHYLATION; FEMALE; GENES, TUMOR SUPPRESSOR; HUMANS; INFANT; LEUKEMIA, MYELOID, ACUTE; MALE; MICRORNAS; PROMOTER REGIONS, GENETIC; SEQUENCE ANALYSIS, DNA; TRANSCRIPTION, GENETIC;

EID: 84880335447     PISSN: None     EISSN: 14712350     Source Type: Journal    
DOI: 10.1186/1471-2350-14-74     Document Type: Article

References (27)

1. Estey E, Dohner H. Acute myeloid leukaemia. Lancet 2006, 368(9550):1894-1907. 10.1016/S0140-6736(06)69780-8, 17126723.
2. Plass C, Oakes C, Blum W, Marcucci G. Epigenetics in acute myeloid leukemia. Semin Oncol 2008, 35(4):378-387. 10.1053/j.seminoncol.2008.04.008, 3463865, 18692688.
3. Issa JP. CpG island methylator phenotype in cancer. Nat Rev Cancer 2004, 4(12):988-993. 10.1038/nrc1507, 15573120.
4. Boultwood J, Wainscoat JS. Gene silencing by DNA methylation in haematological malignancies. Br J Haematol 2007, 138(1):3-11. 10.1111/j.1365-2141.2007.06604.x, 17489980.
5. Savickiene J, Treigyte G, Borutinskaite VV, Navakauskiene R. Antileukemic activity of combined epigenetic agents, DNMT inhibitors zebularine and RG108 with HDAC inhibitors, against promyelocytic leukemia HL-60 cells. Cell Mol Biol Lett 2012, 17(4):501-525. 10.2478/s11658-012-0024-5, 22820861.
6. Trowbridge JJ, Sinha AU, Zhu N, Li M, Armstrong SA, Orkin SH. Haploinsufficiency of Dnmt1 impairs leukemia stem cell function through derepression of bivalent chromatin domains. Genes Dev 2012, 26(4):344-349. 10.1101/gad.184341.111, 3289882, 22345515.
7. Liu L, Ling X, Liang H, Gao Y, Yang H, Shao J, Tang H. Hypomethylation mediated by decreased DNMTs involves in the activation of proto-oncogene MPL in TK6 cells treated with hydroquinone. Toxicol Lett 2012, 209(3):239-245. 10.1016/j.toxlet.2011.12.020, 22245671.
8. Walter MJ, Ding L, Shen D, Shao J, Grillot M, McLellan M, Fulton R, Schmidt H, Kalicki-Veizer J, O'Laughlin M, et al. Recurrent DNMT3A mutations in patients with myelodysplastic syndromes. Leukemia 2011, 25(7):1153-1158. 10.1038/leu.2011.44, 3202965, 21415852.
9. Inaba T. [Epidemiology of leukemia and MDS among atomic bomb survivors in Hiroshima and Nagasaki suggests how abnormal epigenetic regulation contributes to leukemogenesis]. Rinsho Ketsueki 2009, 50(10):1548-1552.
10. Lehmann U, Hasemeier B, Romermann D, Muller M, Langer F, Kreipe H. Epigenetic inactivation of microRNA genes in mammary carcinoma. Verh Dtsch Ges Pathol 2007, 91:214-220.
11. Stumpel DJ, Schotte D, Lange-Turenhout EA, Schneider P, Seslija L, De Menezes RX, Marquez VE, Pieters R, Den Boer ML, Stam RW. Hypermethylation of specific microRNA genes in MLL-rearranged infant acute lymphoblastic leukemia: major matters at a micro scale. Leukemia 2011, 25(3):429-439. 10.1038/leu.2010.282, 21116279.
12. Svedruzic ZM, Reich NO. DNA cytosine C5 methyltransferase Dnmt1: catalysis-dependent release of allosteric inhibition. Biochemistry 2005, 44(27):9472-9485. 10.1021/bi050295z, 15996102.
13. Garzon R, Liu S, Fabbri M, Liu Z, Heaphy CE, Callegari E, Schwind S, Pang J, Yu J, Muthusamy N, et al. MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1. Blood 2009, 113(25):6411-6418. 10.1182/blood-2008-07-170589, 2710934, 19211935.
14. Afonyushkin T, Oskolkova OV, Bochkov VN. Permissive role of miR-663 in induction of VEGF and activation of the ATF4 branch of unfolded protein response in endothelial cells by oxidized phospholipids. Atherosclerosis 2012, 225(1):50-55. 10.1016/j.atherosclerosis.2012.06.016, 22776647.
15. Pan J, Hu H, Zhou Z, Sun L, Peng L, Yu L, Sun L, Liu J, Yang Z, Ran Y. Tumor-suppressive mir-663 gene induces mitotic catastrophe growth arrest in human gastric cancer cells. Oncol Rep 2010, 24(1):105-112.
16. Pizzimenti S, Ferracin M, Sabbioni S, Toaldo C, Pettazzoni P, Dianzani MU, Negrini M, Barrera G. MicroRNA expression changes during human leukemic HL-60 cell differentiation induced by 4-hydroxynonenal, a product of lipid peroxidation. Free Radic Biol Med 2009, 46(2):282-288. 10.1016/j.freeradbiomed.2008.10.035, 19022373.
17. Lehmann U, Hasemeier B, Christgen M, Muller M, Romermann D, Langer F, Kreipe H. Epigenetic inactivation of microRNA gene hsa-mir-9-1 in human breast cancer. J Pathol 2008, 214(1):17-24. 10.1002/path.2251, 17948228.
18. Jian P, Li ZW, Fang TY, Jian W, Zhuan Z, Mei LX, Yan WS, Jian N. Retinoic acid induces HL-60 cell differentiation via the upregulation of miR-663. J Hematol Oncol 2011, 4:20. 10.1186/1756-8722-4-20, 3094392, 21518431.
19. Tili E, Michaille JJ, Adair B, Alder H, Limagne E, Taccioli C, Ferracin M, Delmas D, Latruffe N, Croce CM. Resveratrol decreases the levels of miR-155 by upregulating miR-663, a microRNA targeting JunB and JunD. Carcinogenesis 2010, 31(9):1561-1566. 10.1093/carcin/bgq143, 20622002.
20. Tili E, Michaille JJ. Resveratrol, MicroRNAs, inflammation, and cancer. J Nucleic Acids 2011, 2011:102431. 3154569, 21845215.
21. Tili E, Michaille JJ, Alder H, Volinia S, Delmas D, Latruffe N, Croce CM. Resveratrol modulates the levels of microRNAs targeting genes encoding tumor-suppressors and effectors of TGFbeta signaling pathway in SW480 cells. Biochem Pharmacol 2010, 80(12):2057-2065. 10.1016/j.bcp.2010.07.003, 20637737.
22. Liu ZY, Zhang GL, Wang MM, Xiong YN, Cui HQ. MicroRNA-663 targets TGFB1 and regulates lung cancer proliferation. Asian Pac J Cancer Prev 2011, 12(11):2819-2823.
23. Ni CW, Qiu H, Jo H. MicroRNA-663 upregulated by oscillatory shear stress plays a role in inflammatory response of endothelial cells. Am J Physiol Heart Circ Physiol 2011, 300(5):1762-1769.
24. Yi C, Wang Q, Wang L, Huang Y, Li L, Liu L, Zhou X, Xie G, Kang T, Wang H, et al. MiR-663, a microRNA targeting p21(WAF1/CIP1), promotes the proliferation and tumorigenesis of nasopharyngeal carcinoma. Oncogene 2012, 31(41):4421-4433. 10.1038/onc.2011.629, 22249270.
25. Cheng Y, Geng H, Cheng SH, Liang P, Bai Y, Li J, Srivastava G, Ng MH, Fukagawa T, Wu X, et al. KRAB zinc finger protein ZNF382 is a proapoptotic tumor suppressor that represses multiple oncogenes and is commonly silenced in multiple carcinomas. Cancer Res 2010, 70(16):6516-6526. 10.1158/0008-5472.CAN-09-4566, 20682794.
26. Yang Y, Wang LL, Li YH, Gao XN, Liu Y, Yu L. Effect of CpG island methylation on microRNA expression in the k-562 cell line. Biochem Genet 2012, 50(1-2):122-134.
27. Yang Y, Wang LL, Li YH, Gao XN, Yu L. [Expression level of miRNA-663 in different leukemic cell lines and its biological function]. Zhongguo Shi Yan Xue Ye Xue Za Zhi 2011, 19(2):279-283.