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Volumn 62, Issue 6, 2013, Pages 1040-1045

Urinary excretion of C5b-9 in severe preeclampsia tipping the balance of complement activation in pregnancy

Author keywords

Complement system proteins; Eculizumab; Hellp syndrome; Preeclampsia; Pregnancy

Indexed keywords

COMPLEMENT COMPONENT C3A; COMPLEMENT COMPONENT C5A; COMPLEMENT MEMBRANE ATTACK COMPLEX; COMPLEMENT; ECULIZUMAB;

EID: 84891594043     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.113.01420     Document Type: Article
Times cited : (96)

References (52)
  • 4
    • 0017769046 scopus 로고
    • Circulating immune complexes in normal human pregnancy
    • Masson PL, Delire M, Cambiaso CL. Circulating immune complexes in normal human pregnancy. Nature. 1977;266:542-543.
    • (1977) Nature , vol.266 , pp. 542-543
    • Masson, P.L.1    Delire, M.2    Cambiaso, C.L.3
  • 6
    • 0038335391 scopus 로고    scopus 로고
    • Hypoxia favours necrotic versus apoptotic shedding of placental syncytiotrophoblast into the maternal circulation
    • Huppertz B, Kingdom J, Caniggia I, Desoye G, Black S, Korr H, et al. Hypoxia favours necrotic versus apoptotic shedding of placental syncytiotrophoblast into the maternal circulation. Placenta. 2003;24:181-190.
    • (2003) Placenta , vol.24 , pp. 181-190
    • Huppertz, B.1    Kingdom, J.2    Caniggia, I.3    Desoye, G.4    Black, S.5    Korr, H.6
  • 7
    • 18744415967 scopus 로고    scopus 로고
    • Fetal DNA clearance from maternal plasma is impaired in preeclampsia
    • Lau TW, Leung TN, Chan LY, Lau TK, Chan KC, Tam WH, et al. Fetal DNA clearance from maternal plasma is impaired in preeclampsia. Clin Chem. 2002;48:2141-2146.
    • (2002) Clin Chem. , vol.48 , pp. 2141-2146
    • Lau, T.W.1    Leung, T.N.2    Chan, L.Y.3    Lau, T.K.4    Chan, K.C.5    Tam, W.H.6
  • 8
    • 0035154948 scopus 로고    scopus 로고
    • Increased maternal plasma fetal DNA concentrations in women who eventually develop preeclampsia
    • Leung TN, Zhang J, Lau TK, Chan LY, Lo YM. Increased maternal plasma fetal DNA concentrations in women who eventually develop preeclampsia. Clin Chem. 2001;47:137-139.
    • (2001) Clin Chem. , vol.47 , pp. 137-139
    • Leung, T.N.1    Zhang, J.2    Lau, T.K.3    Chan, L.Y.4    Lo, Y.M.5
  • 9
    • 33644668323 scopus 로고    scopus 로고
    • Preeclampsia: The death of Goliath
    • Feinberg BB. Preeclampsia: the death of Goliath. Am J Reprod Immunol. 2006;55:84-98.
    • (2006) Am J Reprod Immunol. , vol.55 , pp. 84-98
    • Feinberg, B.B.1
  • 12
    • 41349089497 scopus 로고    scopus 로고
    • Alternative complement pathway activation fragment Bb in early pregnancy as a predictor of preeclampsia
    • Lynch AM, Murphy JR, Byers T, Gibbs RS, Neville MC, Giclas PC, et al. Alternative complement pathway activation fragment Bb in early pregnancy as a predictor of preeclampsia. Am J Obstet Gynecol. 2008;198:385.e1-385.e9.
    • (2008) Am J Obstet Gynecol. , vol.198
    • Lynch, A.M.1    Murphy, J.R.2    Byers, T.3    Gibbs, R.S.4    Neville, M.C.5    Giclas, P.C.6
  • 13
    • 0026513933 scopus 로고
    • Complement, neutrophil, and macrophage activation in women with severe preeclampsia and the syndrome of hemolysis, elevated liver enzymes, and low platelet count
    • Haeger M, Unander M, Norder-Hansson B, Tylman M, Bengtsson A. Complement, neutrophil, and macrophage activation in women with severe preeclampsia and the syndrome of hemolysis, elevated liver enzymes, and low platelet count. Obstet Gynecol. 1992;79:19-26.
    • (1992) Obstet Gynecol. , vol.79 , pp. 19-26
    • Haeger, M.1    Unander, M.2    Norder-Hansson, B.3    Tylman, M.4    Bengtsson, A.5
  • 15
    • 77950628595 scopus 로고    scopus 로고
    • Activation of the complement system in normal pregnancy and preeclampsia
    • Derzsy Z, Prohászka Z, Rigó J Jr, Füst G, Molvarec A. Activation of the complement system in normal pregnancy and preeclampsia. Mol Immunol. 2010;47:1500-1506.
    • (2010) Mol Immunol. , vol.47 , pp. 1500-1506
    • Derzsy, Z.1    Prohászka, Z.2    Rigó Jr., J.3    Füst, G.4    Molvarec, A.5
  • 19
    • 0029011719 scopus 로고
    • Urinary excretion of protectin (CD59), complement SC5b-9 and cytokines in membranous glomerulonephritis
    • Lehto T, Honkanen E, Teppo AM, Meri S. Urinary excretion of protectin (CD59), complement SC5b-9 and cytokines in membranous glomerulonephritis. Kidney Int. 1995;47:1403-1411.
    • (1995) Kidney Int. , vol.47 , pp. 1403-1411
    • Lehto, T.1    Honkanen, E.2    Teppo, A.M.3    Meri, S.4
  • 20
    • 0028845893 scopus 로고
    • Urinary C5b-9 excretion and clinical course in idiopathic human membranous nephropathy
    • Kon SP, Coupes B, Short CD, Solomon LR, Raftery MJ, Mallick NP, et al. Urinary C5b-9 excretion and clinical course in idiopathic human membranous nephropathy. Kidney Int. 1995;48:1953-1958.
    • (1995) Kidney Int. , vol.48 , pp. 1953-1958
    • Kon, S.P.1    Coupes, B.2    Short, C.D.3    Solomon, L.R.4    Raftery, M.J.5    Mallick, N.P.6
  • 21
    • 0030723790 scopus 로고    scopus 로고
    • Detection of renal allograft rejection by complement components C5A and TCC in plasma and urine
    • Müller TF, Kraus M, Neumann C, Lange H. Detection of renal allograft rejection by complement components C5A and TCC in plasma and urine. J Lab Clin Med. 1997;129:62-71.
    • (1997) J Lab Clin Med. , vol.129 , pp. 62-71
    • Müller, T.F.1    Kraus, M.2    Neumann, C.3    Lange, H.4
  • 22
    • 79955745537 scopus 로고    scopus 로고
    • ACOG practice bulletin. Diagnosis and management of preeclampsia and eclampsia
    • ACOG Committee on Practice Bulletins-Obstetrics
    • ACOG Committee on Practice Bulletins-Obstetrics. ACOG practice bulletin. Diagnosis and management of preeclampsia and eclampsia. Obstet Gynecol. 2002;99:159-167.
    • (2002) Obstet Gynecol. , vol.99 , pp. 159-167
  • 23
    • 0025173837 scopus 로고
    • The HELLP syndrome (hemolysis, elevated liver enzymes, and low platelets): Much ado about nothing?
    • Sibai BM. The HELLP syndrome (hemolysis, elevated liver enzymes, and low platelets): much ado about nothing? Am J Obstet Gynecol. 1990;162:311-316.
    • (1990) Am J Obstet Gynecol. , vol.162 , pp. 311-316
    • Sibai, B.M.1
  • 24
    • 0029998517 scopus 로고    scopus 로고
    • Increased release of tumor necrosis factor-alpha and interleukin-6 in women with the syndrome of hemolysis, elevated liver enzymes, and low platelet count
    • Haeger M, Unander M, Andersson B, Tarkowski A, Arnestad JP, Bengtsson A. Increased release of tumor necrosis factor-alpha and interleukin-6 in women with the syndrome of hemolysis, elevated liver enzymes, and low platelet count. Acta Obstet Gynecol Scand. 1996;75:695-701.
    • (1996) Acta Obstet Gynecol Scand. , vol.75 , pp. 695-701
    • Haeger, M.1    Unander, M.2    Andersson, B.3    Tarkowski, A.4    Arnestad, J.P.5    Bengtsson, A.6
  • 25
    • 17644388462 scopus 로고    scopus 로고
    • Role of C5a in inflammatory responses
    • Guo RF, Ward PA. Role of C5a in inflammatory responses. Annu Rev Immunol. 2005;23:821-852.
    • (2005) Annu Rev Immunol. , vol.23 , pp. 821-852
    • Guo, R.F.1    Ward, P.A.2
  • 26
  • 27
    • 51249107095 scopus 로고    scopus 로고
    • The C5b-9 membrane attack complex of complement activation localizes to villous trophoblast injury in vivo and modulates human trophoblast function in vitro
    • Rampersad R, Barton A, Sadovsky Y, Nelson DM. The C5b-9 membrane attack complex of complement activation localizes to villous trophoblast injury in vivo and modulates human trophoblast function in vitro. Placenta. 2008;29:855-861.
    • (2008) Placenta , vol.29 , pp. 855-861
    • Rampersad, R.1    Barton, A.2    Sadovsky, Y.3    Nelson, D.M.4
  • 28
    • 79954469179 scopus 로고    scopus 로고
    • Requirements for membrane attack complex formation and anaphylatoxins binding to collagen-activated platelets
    • Martel C, Cointe S, Maurice P, Matar S, Ghitescu M, Théroux P, et al. Requirements for membrane attack complex formation and anaphylatoxins binding to collagen-activated platelets. PLoS One. 2011;6:e18812.
    • (2011) PLoS One , vol.6
    • Martel, C.1    Cointe, S.2    Maurice, P.3    Matar, S.4    Ghitescu, M.5    Théroux, P.6
  • 29
    • 77954313737 scopus 로고    scopus 로고
    • Complement activation on platelets: Implications for vascular inflammation and thrombosis
    • Peerschke EI, Yin W, Ghebrehiwet B. Complement activation on platelets: implications for vascular inflammation and thrombosis. Mol Immunol. 2010;47:2170-2175.
    • (2010) Mol Immunol. , vol.47 , pp. 2170-2175
    • Peerschke, E.I.1    Yin, W.2    Ghebrehiwet, B.3
  • 30
    • 0024253430 scopus 로고
    • Complement proteins C5b-9 cause release of membrane vesicles from the platelet surface that are enriched in the membrane receptor for coagulation factor Va and express prothrombinase activity
    • Sims PJ, Faioni EM, Wiedmer T, Shattil SJ. Complement proteins C5b-9 cause release of membrane vesicles from the platelet surface that are enriched in the membrane receptor for coagulation factor Va and express prothrombinase activity. J Biol Chem. 1988;263:18205-18212.
    • (1988) J Biol Chem. , vol.263 , pp. 18205-18212
    • Sims, P.J.1    Faioni, E.M.2    Wiedmer, T.3    Shattil, S.J.4
  • 32
    • 33748450585 scopus 로고    scopus 로고
    • Complement activation induces dysregulation of angiogenic factors and causes fetal rejection and growth restriction
    • Girardi G, Yarilin D, Thurman JM, Holers VM, Salmon JE. Complement activation induces dysregulation of angiogenic factors and causes fetal rejection and growth restriction. J Exp Med. 2006;203:2165-2175.
    • (2006) J Exp Med. , vol.203 , pp. 2165-2175
    • Girardi, G.1    Yarilin, D.2    Thurman, J.M.3    Holers, V.M.4    Salmon, J.E.5
  • 33
    • 0037373006 scopus 로고    scopus 로고
    • Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia
    • Maynard SE, Min JY, Merchan J, Lim KH, Li J, Mondal S, et al. Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia. J Clin Invest. 2003;111:649-658.
    • (2003) J Clin Invest. , vol.111 , pp. 649-658
    • Maynard, S.E.1    Min, J.Y.2    Merchan, J.3    Lim, K.H.4    Li, J.5    Mondal, S.6
  • 35
    • 0027932151 scopus 로고
    • Plasma clearance of the human C5a anaphylatoxin by binding to leucocyte C5a receptors
    • Oppermann M, Götze O. Plasma clearance of the human C5a anaphylatoxin by binding to leucocyte C5a receptors. Immunology. 1994;82:516-521.
    • (1994) Immunology , vol.82 , pp. 516-521
    • Oppermann, M.1    Götze, O.2
  • 36
    • 18544410664 scopus 로고    scopus 로고
    • Predictors of pre-eclampsia in women at high risk. National Institute of Child Health and Human Development Network of Maternal-Fetal Medicine Units
    • Caritis S, Sibai B, Hauth J, Lindheimer M, Van Dorsten P, Klebanoff M, et al. Predictors of pre-eclampsia in women at high risk. National Institute of Child Health and Human Development Network of Maternal-Fetal Medicine Units. Am J Obstet Gynecol. 1998;179:946-951.
    • (1998) Am J Obstet Gynecol. , vol.179 , pp. 946-951
    • Caritis, S.1    Sibai, B.2    Hauth, J.3    Lindheimer, M.4    Van Dorsten, P.5    Klebanoff, M.6
  • 37
    • 78149477844 scopus 로고    scopus 로고
    • Molecular intercommunication between the complement and coagulation systems
    • Amara U, Flierl MA, Rittirsch D, Klos A, Chen H, Acker B, et al. Molecular intercommunication between the complement and coagulation systems. J Immunol. 2010;185:5628-5636.
    • (2010) J Immunol. , vol.185 , pp. 5628-5636
    • Amara, U.1    Flierl, M.A.2    Rittirsch, D.3    Klos, A.4    Chen, H.5    Acker, B.6
  • 39
    • 79953691827 scopus 로고    scopus 로고
    • Mutations in complement regulatory proteins predispose to preeclampsia: A genetic analysis of the PROMISSE cohort
    • Salmon JE, Heuser C, Triebwasser M, Liszewski MK, Kavanagh D, Roumenina L, et al. Mutations in complement regulatory proteins predispose to preeclampsia: a genetic analysis of the PROMISSE cohort. PLoS Med. 2011;8:e1001013.
    • (2011) PLoS Med. , vol.8
    • Salmon, J.E.1    Heuser, C.2    Triebwasser, M.3    Liszewski, M.K.4    Kavanagh, D.5    Roumenina, L.6
  • 40
    • 84865828986 scopus 로고    scopus 로고
    • Novel insights in localization and expression levels of C5aR and C5L2 under native and post-transplant conditions in the kidney
    • van Werkhoven MB, Damman J, Daha MR, Krikke C, van Goor H, van Son WJ, et al. Novel insights in localization and expression levels of C5aR and C5L2 under native and post-transplant conditions in the kidney. Mol Immunol. 2013;53:237-245.
    • (2013) Mol Immunol. , vol.53 , pp. 237-245
    • Van Werkhoven, M.B.1    Damman, J.2    Daha, M.R.3    Krikke, C.4    Van Goor, H.5    Van Son, W.J.6
  • 41
    • 0033978132 scopus 로고    scopus 로고
    • The C5a receptor is expressed in normal renal proximal tubular but not in normal pulmonary or hepatic epithelial cells
    • Fayyazi A, Scheel O, Werfel T, Schweyer S, Oppermann M, Götze O, et al. The C5a receptor is expressed in normal renal proximal tubular but not in normal pulmonary or hepatic epithelial cells. Immunology. 2000;99:38-45.
    • (2000) Immunology , vol.99 , pp. 38-45
    • Fayyazi, A.1    Scheel, O.2    Werfel, T.3    Schweyer, S.4    Oppermann, M.5    Götze, O.6
  • 42
  • 43
    • 0024365084 scopus 로고
    • Transcellular transport and membrane insertion of the C5b-9 membrane attack complex of complement by glomerular epithelial cells in experimental membranous nephropathy
    • Kerjaschki D, Schulze M, Binder S, Kain R, Ojha PP, Susani M, et al. Transcellular transport and membrane insertion of the C5b-9 membrane attack complex of complement by glomerular epithelial cells in experimental membranous nephropathy. J Immunol. 1989;143:546-552.
    • (1989) J Immunol. , vol.143 , pp. 546-552
    • Kerjaschki, D.1    Schulze, M.2    Binder, S.3    Kain, R.4    Ojha, P.P.5    Susani, M.6
  • 46
    • 0032957844 scopus 로고    scopus 로고
    • Preeclampsia: An excessive maternal inflammatory response to pregnancy
    • Redman CW, Sacks GP, Sargent IL. Preeclampsia: an excessive maternal inflammatory response to pregnancy. Am J Obstet Gynecol. 1999;180(2 Pt 1):499-506.
    • (1999) Am J Obstet Gynecol. , vol.180 , Issue.2 PART 1 , pp. 499-506
    • Redman, C.W.1    Sacks, G.P.2    Sargent, I.L.3
  • 47
    • 0021952732 scopus 로고
    • Chemotactic responses of human peripheral blood monocytes to the complement-derived peptides C5a and C5a des Arg
    • Marder SR, Chenoweth DE, Goldstein IM, Perez HD. Chemotactic responses of human peripheral blood monocytes to the complement-derived peptides C5a and C5a des Arg. J Immunol. 1985;134:3325-3331.
    • (1985) J Immunol. , vol.134 , pp. 3325-3331
    • Marder, S.R.1    Chenoweth, D.E.2    Goldstein, I.M.3    Perez, H.D.4
  • 48
    • 77952885661 scopus 로고    scopus 로고
    • The intrinsic complement regulator decay-accelerating factor modulates the biological response to vascular injury
    • Sakuma M, Morooka T, Wang Y, Shi C, Croce K, Gao H, et al. The intrinsic complement regulator decay-accelerating factor modulates the biological response to vascular injury. Arterioscler Thromb Vasc Biol. 2010;30:1196-1202.
    • (2010) Arterioscler Thromb Vasc Biol. , vol.30 , pp. 1196-1202
    • Sakuma, M.1    Morooka, T.2    Wang, Y.3    Shi, C.4    Croce, K.5    Gao, H.6
  • 49
    • 84855278759 scopus 로고    scopus 로고
    • Complement-mediated injury and protection of endothelium: Lessons from atypical haemolytic uraemic syndrome
    • Kerr H, Richards A. Complement-mediated injury and protection of endothelium: lessons from atypical haemolytic uraemic syndrome. Immunobiology. 2012;217:195-203.
    • (2012) Immunobiology. , vol.217 , pp. 195-203
    • Kerr, H.1    Richards, A.2
  • 50
    • 0018093401 scopus 로고
    • Oxygen radicals mediate endothelial cell damage by complement-stimulated granulocytes. An in vitro model of immune vascular damage
    • Sacks T, Moldow CF, Craddock PR, Bowers TK, Jacob HS. Oxygen radicals mediate endothelial cell damage by complement-stimulated granulocytes. An in vitro model of immune vascular damage. J Clin Invest. 1978;61:1161-1167.
    • (1978) J Clin Invest. , vol.61 , pp. 1161-1167
    • Sacks, T.1    Moldow, C.F.2    Craddock, P.R.3    Bowers, T.K.4    Jacob, H.S.5
  • 51
    • 70449370354 scopus 로고    scopus 로고
    • Lipid peroxidation and antioxidant status in preeclampsia: A systematic review
    • Gupta S, Aziz N, Sekhon L, Agarwal R, Mansour G, Li J, et al. Lipid peroxidation and antioxidant status in preeclampsia: a systematic review. Obstet Gynecol Surv. 2009;64:750-759.
    • (2009) Obstet Gynecol Surv. , vol.64 , pp. 750-759
    • Gupta, S.1    Aziz, N.2    Sekhon, L.3    Agarwal, R.4    Mansour, G.5    Li, J.6
  • 52
    • 84873288473 scopus 로고    scopus 로고
    • Eculizumab for the treatment of preeclampsia/HELLP syndrome
    • Burwick RM, Feinberg BB. Eculizumab for the treatment of preeclampsia/HELLP syndrome. Placenta. 2013;34:201-203.
    • (2013) Placenta , vol.34 , pp. 201-203
    • Burwick, R.M.1    Feinberg, B.B.2


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