메뉴 건너뛰기




Volumn 39, Issue 1, 2014, Pages 44-48

Head and neck tumor hypoxia imaging by 18F-fluoroazomycin- arabinoside (18F-FAZA)-PET: A review

Author keywords

18F FAZA; Head and neck cancer; Hypoxia

Indexed keywords

1 FLUORO 3 (2 NITRO 1 IMIDAZOLYL) 2 PROPANOL F 18; FLUOROAZOMYCIN ARABINOSIDE F 18; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

EID: 84891559809     PISSN: 03639762     EISSN: 15360229     Source Type: Journal    
DOI: 10.1097/RLU.0000000000000286     Document Type: Review
Times cited : (48)

References (56)
  • 1
    • 1642565876 scopus 로고    scopus 로고
    • Tumor hypoxia and malignant progression
    • Vaupel P, Mayer A, Hockel M. Tumor hypoxia and malignant progression. Methods Enzymol. 2004;381:335-354
    • (2004) Methods Enzymol , vol.381 , pp. 335-354
    • Vaupel, P.1    Mayer, A.2    Hockel, M.3
  • 2
    • 0036359548 scopus 로고    scopus 로고
    • HypoxiaVa key regulatory factor in tumour growth
    • Harris AL. HypoxiaVa key regulatory factor in tumour growth. Nat Rev Cancer. 2002;2:38-47
    • (2002) Nat Rev Cancer , vol.2 , pp. 38-47
    • Harris, A.L.1
  • 4
    • 0034083413 scopus 로고    scopus 로고
    • Oxygenation of advanced head and neck cancer: Prognostic marker for the response to primary radiochemotherapy
    • Vanselow B, Eble MJ, Rudat V, et al. Oxygenation of advanced head and neck cancer: Prognostic marker for the response to primary radiochemotherapy. Otolaryngol Head Neck Surg. 2000;122:856-862
    • (2000) Otolaryngol Head Neck Surg , vol.122 , pp. 856-862
    • Vanselow, B.1    Eble, M.J.2    Rudat, V.3
  • 5
    • 14844292125 scopus 로고    scopus 로고
    • Pretreatment anemia is correlated with the reduced effectiveness of radiation and concurrent chemotherapy in advanced head and neck cancer
    • Prosnitz RG, Yao B, Farrell CL, et al. Pretreatment anemia is correlated with the reduced effectiveness of radiation and concurrent chemotherapy in advanced head and neck cancer. Int J Radiat Oncol Biol Phys. 2005;61:1087-1095
    • (2005) Int J Radiat Oncol Biol Phys , vol.61 , pp. 1087-1095
    • Prosnitz, R.G.1    Yao, B.2    Farrell, C.L.3
  • 6
    • 33750108975 scopus 로고    scopus 로고
    • Hypoxia in head and neck cancer
    • Isa AY, Ward TH, West CM, et al. Hypoxia in head and neck cancer. Br J Radiol. 2006;79:791-798
    • (2006) Br J Radiol , vol.79 , pp. 791-798
    • Isa, A.Y.1    Ward, T.H.2    West, C.M.3
  • 7
    • 34547121206 scopus 로고    scopus 로고
    • Hypoxia in cancer: Significance and impact on clinical outcome
    • Vaupel P, Mayer A. Hypoxia in cancer: Significance and impact on clinical outcome. Cancer Metastasis Rev. 2007;26:225-239
    • (2007) Cancer Metastasis Rev , vol.26 , pp. 225-239
    • Vaupel, P.1    Mayer, A.2
  • 8
    • 0033048571 scopus 로고    scopus 로고
    • Tissue oxygen distribution in head and neck cancer patients
    • Adam MF, Gabalski EC, Bloch DA, et al. Tissue oxygen distribution in head and neck cancer patients. Head Neck. 1999;21:146-153
    • (1999) Head Neck , vol.21 , pp. 146-153
    • Adam, M.F.1    Gabalski, E.C.2    Bloch, D.A.3
  • 10
    • 0029955072 scopus 로고    scopus 로고
    • Pretreatment oxygenation predicts radiation response in advanced squamous cell carcinoma of the head and neck
    • Nordsmark M, Overgaard M, Overgaard J. Pretreatment oxygenation predicts radiation response in advanced squamous cell carcinoma of the head and neck. Radiother Oncol. 1996;41:31-39
    • (1996) Radiother Oncol , vol.41 , pp. 31-39
    • Nordsmark, M.1    Overgaard, M.2    Overgaard, J.3
  • 11
    • 0030742027 scopus 로고    scopus 로고
    • Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck
    • Brizel DM, Sibley GS, Prosnitz LR, et al. Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck. Int J Radiat Oncol Biol Phys. 1997;38:285-289
    • (1997) Int J Radiat Oncol Biol Phys , vol.38 , pp. 285-289
    • Brizel, D.M.1    Sibley, G.S.2    Prosnitz, L.R.3
  • 12
    • 0344936018 scopus 로고    scopus 로고
    • Oxygenation of squamous cell carcinoma of the head and neck: Comparison of primary tumors, neck node metastases, and normal tissue
    • Becker A, Hansgen G, Bloching M, et al. Oxygenation of squamous cell carcinoma of the head and neck: Comparison of primary tumors, neck node metastases, and normal tissue. Int J Radiat Oncol Biol Phys. 1998;42:35-41
    • (1998) Int J Radiat Oncol Biol Phys , vol.42 , pp. 35-41
    • Becker, A.1    Hansgen, G.2    Bloching, M.3
  • 13
    • 0037963317 scopus 로고    scopus 로고
    • Comparison of the comet assay and the oxygen microelectrode for measuring tumor oxygenation in head-And-neck cancer patients
    • Le QT, Kovacs MS, Dorie MJ, et al. Comparison of the comet assay and the oxygen microelectrode for measuring tumor oxygenation in head-And-neck cancer patients. Int J Radiat Oncol Biol Phys. 2003;56:375-383
    • (2003) Int J Radiat Oncol Biol Phys , vol.56 , pp. 375-383
    • Le, Q.T.1    Kovacs, M.S.2    Dorie, M.J.3
  • 14
    • 33748185692 scopus 로고    scopus 로고
    • Imaging hypoxia after oxygenation-modification: Comparing [18f]fmiso autoradiography with pimonidazole immunohistochemistry in human xenograft tumors
    • Troost EG, Laverman P, Kaanders JH, et al. Imaging hypoxia after oxygenation-modification: Comparing [18F]FMISO autoradiography with pimonidazole immunohistochemistry in human xenograft tumors. Radiother Oncol. 2006;80:157-164
    • (2006) Radiother Oncol , vol.80 , pp. 157-164
    • Troost, E.G.1    Laverman, P.2    Kaanders, J.H.3
  • 15
    • 34547984111 scopus 로고    scopus 로고
    • PO polarography, contrast enhanced color duplex sonography (CDS), [18F] fluoromisonidazole and [18F] fluorodeoxyglucose positron emission tomography: Validated methods for the evaluation of therapyrelevant tumor oxygenation or only bricks in the puzzle of tumor hypoxia?
    • Gagel B, Piroth M, Pinkawa M, et al. PO polarography, contrast enhanced color duplex sonography (CDS), [18F] fluoromisonidazole and [18F] fluorodeoxyglucose positron emission tomography: Validated methods for the evaluation of therapyrelevant tumor oxygenation or only bricks in the puzzle of tumor hypoxia? BMC Cancer. 2007;7:113
    • (2007) BMC Cancer , vol.7 , pp. 113
    • Gagel, B.1    Piroth, M.2    Pinkawa, M.3
  • 16
    • 34548511596 scopus 로고    scopus 로고
    • Hypoxia imaging with FAZA-PET and theoretical considerations with regard to dose painting for individualization of radiotherapy in patients with head and neck cancer
    • Grosu AL, Souvatzoglou M, Roper B, et al. Hypoxia imaging with FAZA-PET and theoretical considerations with regard to dose painting for individualization of radiotherapy in patients with head and neck cancer. Int J Radiat Oncol Biol Phys. 2007;69:541-551
    • (2007) Int J Radiat Oncol Biol Phys , vol.69 , pp. 541-551
    • Grosu, A.L.1    Souvatzoglou, M.2    Roper, B.3
  • 17
    • 33749344131 scopus 로고    scopus 로고
    • Tumor hypoxia imaging with [F-18] fluoromisonidazole positron emission tomography in head and neck cancer
    • Rajendran JG, Schwartz DL, O'Sullivan J, et al. Tumor hypoxia imaging with [F-18] fluoromisonidazole positron emission tomography in head and neck cancer. Clin Cancer Res. 2006;12:5435-5441
    • (2006) Clin Cancer Res , vol.12 , pp. 5435-5441
    • Rajendran, J.G.1    Schwartz, D.L.2    O'Sullivan, J.3
  • 18
    • 33646454133 scopus 로고    scopus 로고
    • Prognostic significance of [18F]-misonidazole positron emission tomography-detected tumor hypoxia in patients with advanced head and neck cancer randomly assigned to chemoradiation with or without tirapazamine: A substudy of trans-Tasman radiation oncology group study 98.02
    • Rischin D, Hicks RJ, Fisher R, et al. Prognostic significance of [18F]-misonidazole positron emission tomography-detected tumor hypoxia in patients with advanced head and neck cancer randomly assigned to chemoradiation with or without tirapazamine: A substudy of trans-Tasman radiation oncology group study 98.02. J Clin Oncol. 2006;24:2098-2104
    • (2006) J Clin Oncol , vol.24 , pp. 2098-2104
    • Rischin, D.1    Hicks, R.J.2    Fisher, R.3
  • 19
    • 15844368087 scopus 로고    scopus 로고
    • Prognostic impact of hypoxia imaging with 18F-misonidazole PET in nonYsmall cell lung cancer and head and neck cancer before radiotherapy
    • Eschmann SM, Paulsen F, Reimold M, et al. Prognostic impact of hypoxia imaging with 18F-misonidazole PET in nonYsmall cell lung cancer and head and neck cancer before radiotherapy. J Nucl Med. 2005;46:253-260
    • (2005) J Nucl Med , vol.46 , pp. 253-260
    • Eschmann, S.M.1    Paulsen, F.2    Reimold, M.3
  • 20
    • 33748045490 scopus 로고    scopus 로고
    • Combined uptake of [18F]FDG and [18F]FMISO correlates with radiation therapy outcome in head-And-neck cancer patients
    • Thorwarth D, Eschmann SM, Holzner F, et al. Combined uptake of [18F]FDG and [18F]FMISO correlates with radiation therapy outcome in head-And-neck cancer patients. Radiother Oncol. 2006;80:151-156
    • (2006) Radiother Oncol , vol.80 , pp. 151-156
    • Thorwarth, D.1    Eschmann, S.M.2    Holzner, F.3
  • 21
    • 34250334707 scopus 로고    scopus 로고
    • Hypoxia-imaging with (18)Fmisonidazole and PET: Changes of kinetics during radiotherapy of head-Andneck cancer
    • Eschmann SM, Paulsen F, Bedeshem C, et al. Hypoxia-imaging with (18)Fmisonidazole and PET: Changes of kinetics during radiotherapy of head-Andneck cancer. Radiother Oncol. 2007;83:406-410
    • (2007) Radiother Oncol , vol.83 , pp. 406-410
    • Eschmann, S.M.1    Paulsen, F.2    Bedeshem, C.3
  • 22
    • 84868360868 scopus 로고    scopus 로고
    • Exploratory prospective trial of hypoxiaspecific PET imaging during radiochemotherapy in patients with locally advanced head-And-neck cancer
    • Zips D, Zophel K, Abolmaali N, et al. Exploratory prospective trial of hypoxiaspecific PET imaging during radiochemotherapy in patients with locally advanced head-And-neck cancer. Radiother Oncol. 2012;105:21-28
    • (2012) Radiother Oncol , vol.105 , pp. 21-28
    • Zips, D.1    Zophel, K.2    Abolmaali, N.3
  • 23
    • 41949118216 scopus 로고    scopus 로고
    • Role of positron emission tomography in the management of head and neck cancer in the molecular therapy era
    • Garcia C, Flamen P. Role of positron emission tomography in the management of head and neck cancer in the molecular therapy era. Curr Opin Oncol. 2008;20:275-279
    • (2008) Curr Opin Oncol , vol.20 , pp. 275-279
    • Garcia, C.1    Flamen, P.2
  • 24
    • 80052278041 scopus 로고    scopus 로고
    • Preclinical evaluation and validation of [18f]hx4 a promising hypoxia marker for pet imaging
    • Dubois LJ, Lieuwes NG, Janssen MH, et al. Preclinical evaluation and validation of [18F]HX4, a promising hypoxia marker for PET imaging. Proc Natl Acad Sci U S A. 2011;108:14620-14625
    • (2011) Proc Natl Acad Sci U S A. , vol.108 , pp. 14620-14625
    • Dubois, L.J.1    Lieuwes, N.G.2    Janssen, M.H.3
  • 25
    • 84865709437 scopus 로고    scopus 로고
    • 1)(8)F-HX4 hypoxia imaging with PET/CT in head and neck cancer: A comparison with (1)(8)F-FMISO
    • Chen L, Zhang Z, Kolb HC, et al. (1)(8)F-HX4 hypoxia imaging with PET/CT in head and neck cancer: A comparison with (1)(8)F-FMISO. Nucl Med Commun. 2012;33:1096-1102
    • (2012) Nucl Med Commun , vol.33 , pp. 1096-1102
    • Chen, L.1    Zhang, Z.2    Kolb, H.C.3
  • 26
    • 57149111715 scopus 로고    scopus 로고
    • 18F-EF5: A new PET tracer for imaging hypoxia in head and neck cancer
    • Komar G, Seppanen M, Eskola O, et al. 18F-EF5: A new PET tracer for imaging hypoxia in head and neck cancer. J Nucl Med. 2008;49:1944-1951
    • (2008) J Nucl Med , vol.49 , pp. 1944-1951
    • Komar, G.1    Seppanen, M.2    Eskola, O.3
  • 27
    • 0038207686 scopus 로고    scopus 로고
    • Quantifying tumour hypoxia with fluorine-18 fluoroerythronitroimidazole ([18F]FETNIM) and PET using the tumour to plasma ratio
    • Lehtio K, Oikonen V, Nyman S, et al. Quantifying tumour hypoxia with fluorine-18 fluoroerythronitroimidazole ([18F]FETNIM) and PET using the tumour to plasma ratio. Eur J Nucl Med Mol Imaging. 2003;30:101-108
    • (2003) Eur J Nucl Med Mol Imaging , vol.30 , pp. 101-108
    • Lehtio, K.1    Oikonen, V.2    Nyman, S.3
  • 28
    • 3042518844 scopus 로고    scopus 로고
    • Imaging perfusion and hypoxia with PET to predict radiotherapy response in head-And-neck cancer
    • Lehtio K, Eskola O, Viljanen T, et al. Imaging perfusion and hypoxia with PET to predict radiotherapy response in head-And-neck cancer. Int J Radiat Oncol Biol Phys. 2004;59:971-982
    • (2004) Int J Radiat Oncol Biol Phys , vol.59 , pp. 971-982
    • Lehtio, K.1    Eskola, O.2    Viljanen, T.3
  • 29
    • 0035869722 scopus 로고    scopus 로고
    • A novel approach to overcome hypoxic tumor resistance: Cu-ATSMYguided intensity-modulated radiation therapy
    • Chao KS, Bosch WR, Mutic S, et al. A novel approach to overcome hypoxic tumor resistance: Cu-ATSMYguided intensity-modulated radiation therapy. Int J Radiat Oncol Biol Phys. 2001;49:1171-1182
    • (2001) Int J Radiat Oncol Biol Phys , vol.49 , pp. 1171-1182
    • Chao, K.S.1    Bosch, W.R.2    Mutic, S.3
  • 30
    • 15944397653 scopus 로고    scopus 로고
    • Preparation of the hypoxia imaging pet tracer [18f]faza: Reaction parameters and automation
    • Reischl G, Ehrlichmann W, Bieg C, et al. Preparation of the hypoxia imaging PET tracer [18F]FAZA: Reaction parameters and automation. Appl Radiat Isot. 2005;62:897-901
    • (2005) Appl Radiat Isot , vol.62 , pp. 897-901
    • Reischl, G.1    Ehrlichmann, W.2    Bieg, C.3
  • 31
    • 0032923678 scopus 로고    scopus 로고
    • Fluoroazomycin arabinoside (FAZA): Syn thesis, 2H and 3H-labelling and preliminary biological evaluation of a novel 2-nitroimidazole marker of tissue hypoxia
    • Kumar P, Stypinski D, Xie H, et al. Fluoroazomycin arabinoside (FAZA): Synthesis, 2H and 3H-labelling and preliminary biological evaluation of a novel 2-nitroimidazole marker of tissue hypoxia. J Label Compounds Radiopharm. 1999;42:3-16
    • (1999) J Label Compounds Radiopharm , vol.42 , pp. 3-16
    • Kumar, P.1    Stypinski, D.2    Xie, H.3
  • 32
    • 58149287834 scopus 로고    scopus 로고
    • Cellular uptake of PET tracers of glucose metabolism and hypoxia and their linkage
    • Busk M, Horsman MR, Jakobsen S, et al. Cellular uptake of PET tracers of glucose metabolism and hypoxia and their linkage. Eur J Nucl Med Mol Imaging. 2008;35:2294-2303
    • (2008) Eur J Nucl Med Mol Imaging , vol.35 , pp. 2294-2303
    • Busk, M.1    Horsman, M.R.2    Jakobsen, S.3
  • 33
    • 0038058799 scopus 로고    scopus 로고
    • 18F] fluoroazomycinarabinofuranoside (18FAZA) and [18F]fluoromisonidazole (18FMISO): A comparative study of their selective uptake in hypoxic cells and PET imaging in experimental rat tumors
    • Sorger D, Patt M, Kumar P, et al. [18F]fluoroazomycinarabinofuranoside (18FAZA) and [18F]fluoromisonidazole (18FMISO): A comparative study of their selective uptake in hypoxic cells and PET imaging in experimental rat tumors. Nucl Med Biol. 2003;30:317-326
    • (2003) Nucl Med Biol , vol.30 , pp. 317-326
    • Sorger, D.1    Patt, M.2    Kumar, P.3
  • 34
    • 15044349250 scopus 로고    scopus 로고
    • Hypoxia-specific tumor imaging with 18F-fluoroazomycin arabinoside
    • Piert M, Machulla HJ, Picchio M, et al. Hypoxia-specific tumor imaging with 18F-fluoroazomycin arabinoside. J Nucl Med. 2005;46:106-113
    • (2005) J Nucl Med , vol.46 , pp. 106-113
    • Piert, M.1    Machulla, H.J.2    Picchio, M.3
  • 35
    • 34250326197 scopus 로고    scopus 로고
    • Pretreatment 18F-FAZA PET predicts success of hypoxia-directed radiochemotherapy using tirapazamine
    • Beck R, Roper B, Carlsen JM, et al. Pretreatment 18F-FAZA PET predicts success of hypoxia-directed radiochemotherapy using tirapazamine. J Nucl Med. 2007;48:973-980
    • (2007) J Nucl Med , vol.48 , pp. 973-980
    • Beck, R.1    Roper, B.2    Carlsen, J.M.3
  • 36
    • 39749202442 scopus 로고    scopus 로고
    • Imaging hypoxia in xenografted and murine tumors with 18F-fluoroazomycin arabinoside: A comparative study involving microPET, autoradiography, PO2-polarography, and fluorescence microscopy
    • Busk M, Horsman MR, Jakobsen S, et al. Imaging hypoxia in xenografted and murine tumors with 18F-fluoroazomycin arabinoside: A comparative study involving microPET, autoradiography, PO2-polarography, and fluorescence microscopy. Int J Radiat Oncol Biol Phys. 2008;70:1202-1212
    • (2008) Int J Radiat Oncol Biol Phys , vol.70 , pp. 1202-1212
    • Busk, M.1    Horsman, M.R.2    Jakobsen, S.3
  • 37
    • 69949180403 scopus 로고    scopus 로고
    • Can hypoxia-PET map hypoxic cell density heterogeneity accurately in an animal tumor model at a clinically obtainable image contrast?
    • Busk M, Horsman MR, Jakobsen S, et al. Can hypoxia-PET map hypoxic cell density heterogeneity accurately in an animal tumor model at a clinically obtainable image contrast? Radiother Oncol. 2009;92:429-436
    • (2009) Radiother Oncol , vol.92 , pp. 429-436
    • Busk, M.1    Horsman, M.R.2    Jakobsen, S.3
  • 38
    • 21844455567 scopus 로고    scopus 로고
    • Hypoxia in head and neck cancer: How much, how important?
    • Janssen HL, Haustermans KM, Balm AJ, et al. Hypoxia in head and neck cancer: How much, how important? Head Neck. 2005;27:622-638
    • (2005) Head Neck , vol.27 , pp. 622-638
    • Janssen, H.L.1    Haustermans, K.M.2    Balm, A.J.3
  • 39
    • 77956566350 scopus 로고    scopus 로고
    • Assessing hypoxia in animal tumor models based on pharmocokinetic analysis of dynamic FAZA PET
    • Busk M, Munk OL, Jakobsen S, et al. Assessing hypoxia in animal tumor models based on pharmocokinetic analysis of dynamic FAZA PET. Acta Oncol. 2010;49:922-933
    • (2010) Acta Oncol , vol.49 , pp. 922-933
    • Busk, M.1    Munk, O.L.2    Jakobsen, S.3
  • 40
    • 82055164095 scopus 로고    scopus 로고
    • Significant impact of different oxygen breathing conditions on noninvasive in vivo tumor-hypoxia imaging using [ (1)(8)F]-fluoro- Azomycinarabino-furanoside ([(1)(8)F]FAZA
    • 717X-6-165
    • Maier FC, Kneilling M, Reischl G, et al. Significant impact of different oxygen breathing conditions on noninvasive in vivo tumor-hypoxia imaging using [(1)(8)F]-fluoro-Azomycinarabino-furanoside ([(1)(8)F]FAZA). Radiat Oncol. 2011;6:165, 717X-6-165
    • (2011) Radiat Oncol , vol.6 , pp. 165
    • Maier, F.C.1    Kneilling, M.2    Reischl, G.3
  • 41
    • 79960370596 scopus 로고    scopus 로고
    • Accessing radiation response using hypoxia PET imaging and oxygen sensitive electrodes: A preclinical study
    • Mortensen LS, Busk M, Nordsmark M, et al. Accessing radiation response using hypoxia PET imaging and oxygen sensitive electrodes: A preclinical study. Radiother Oncol. 2011;99:418-423
    • (2011) Radiother Oncol , vol.99 , pp. 418-423
    • Mortensen, L.S.1    Busk, M.2    Nordsmark, M.3
  • 42
    • 84874108264 scopus 로고    scopus 로고
    • PET hypoxia imaging with FAZA: Reproducibility at baseline and during fractionated radiotherapy in tumour-bearing mice
    • Busk M, Mortensen LS, Nordsmark M, et al. PET hypoxia imaging with FAZA: Reproducibility at baseline and during fractionated radiotherapy in tumour-bearing mice. Eur J Nucl Med Mol Imaging. 2013;40:186-197
    • (2013) Eur J Nucl Med Mol Imaging , vol.40 , pp. 186-197
    • Busk, M.1    Mortensen, L.S.2    Nordsmark, M.3
  • 43
    • 34548485457 scopus 로고    scopus 로고
    • Tumour hypoxia imaging with [18F]FAZA PET in head and neck cancer patients: A pilot study
    • Souvatzoglou M, Grosu AL, Roper B, et al. Tumour hypoxia imaging with [18F]FAZA PET in head and neck cancer patients: A pilot study. Eur J Nucl Med Mol Imaging. 2007;34:1566-1575
    • (2007) Eur J Nucl Med Mol Imaging , vol.34 , pp. 1566-1575
    • Souvatzoglou, M.1    Grosu, A.L.2    Roper, B.3
  • 44
    • 70350532485 scopus 로고    scopus 로고
    • Initial results of hypoxia imaging using 1-Alpha-D: -(5-deoxy-5-[18F]- fluoroarabinofuranosyl)-2-nitroimidazole (18F-FAZA
    • Postema EJ, McEwan AJ, Riauka TA, et al. Initial results of hypoxia imaging using 1-Alpha-D: -(5-deoxy-5-[18F]-fluoroarabinofuranosyl)-2- nitroimidazole (18F-FAZA). Eur J Nucl Med Mol Imaging. 2009;36:1565-1573
    • (2009) Eur J Nucl Med Mol Imaging , vol.36 , pp. 1565-1573
    • Postema, E.J.1    McEwan, A.J.2    Riauka, T.A.3
  • 45
    • 77956589424 scopus 로고    scopus 로고
    • Evaluating repetitive 18Ffluoroazomycin-Arabinoside (18FAZA) PET in the setting of MRI guided adaptive radiotherapy in cervical cancer
    • Schuetz M, Schmid MP, Potter R, et al. Evaluating repetitive 18Ffluoroazomycin-Arabinoside (18FAZA) PET in the setting of MRI guided adaptive radiotherapy in cervical cancer. Acta Oncol. 2010;49:941-947
    • (2010) Acta Oncol , vol.49 , pp. 941-947
    • Schuetz, M.1    Schmid, M.P.2    Potter, R.3
  • 46
    • 77957088726 scopus 로고    scopus 로고
    • Quantitative assessment of hypoxia kinetic models by a cross-study of dynamic 18F-FAZA and 15O-H2O in patients with head and neck tumors
    • Shi K, Souvatzoglou M, Astner ST, et al. Quantitative assessment of hypoxia kinetic models by a cross-study of dynamic 18F-FAZA and 15O-H2O in patients with head and neck tumors. J Nucl Med. 2010;51:1386-1394
    • (2010) J Nucl Med , vol.51 , pp. 1386-1394
    • Shi, K.1    Souvatzoglou, M.2    Astner, S.T.3
  • 47
    • 80455174743 scopus 로고    scopus 로고
    • Investigation on tumor hypoxia in resectable primary prostate cancer as demonstrated by 18F-FAZA PET/CT utilizing multimodality fusion techniques
    • Garcia-Parra R, Wood D, Shah RB, et al. Investigation on tumor hypoxia in resectable primary prostate cancer as demonstrated by 18F-FAZA PET/CT utilizing multimodality fusion techniques. Eur J Nucl Med Mol Imaging. 2011;38:1816-1823
    • (2011) Eur J Nucl Med Mol Imaging , vol.38 , pp. 1816-1823
    • Garcia-Parra, R.1    Wood, D.2    Shah, R.B.3
  • 48
    • 84868367617 scopus 로고    scopus 로고
    • FAZA PET/CT hypoxia imaging in patients with squamous cell carcinoma of the head and neck treated with radiotherapy: Results from the DAHANCA 24 trial
    • Mortensen LS, Johansen J, Kallehauge J, et al. FAZA PET/CT hypoxia imaging in patients with squamous cell carcinoma of the head and neck treated with radiotherapy: Results from the DAHANCA 24 trial. Radiother Oncol. 2012;105:14-20
    • (2012) Radiother Oncol , vol.105 , pp. 14-20
    • Mortensen, L.S.1    Johansen, J.2    Kallehauge, J.3
  • 49
    • 84881426634 scopus 로고    scopus 로고
    • PET imaging of tumor hypoxia using 18F-fluorazomycin arabinoside in stage III-IV nonYsmall cell lung cancer patients
    • Bollineni VR, Kerner GS, Pruim J, et al. PET imaging of tumor hypoxia using 18F-fluorazomycin arabinoside in stage III-IV nonYsmall cell lung cancer patients. J Nucl Med. 2013;54:1175-1180
    • (2013) J Nucl Med , vol.54 , pp. 1175-1180
    • Bollineni, V.R.1    Kerner, G.S.2    Pruim, J.3
  • 50
    • 22244488361 scopus 로고    scopus 로고
    • Radiotherapy alone or combined with carbogen breathing for squamous cell carcinoma of the head and neck: A prospective, randomized trial
    • Mendenhall WM, Morris CG, Amdur RJ, et al. Radiotherapy alone or combined with carbogen breathing for squamous cell carcinoma of the head and neck: A prospective, randomized trial. Cancer. 2005;104:332-337
    • (2005) Cancer , vol.104 , pp. 332-337
    • Mendenhall, W.M.1    Morris, C.G.2    Amdur, R.J.3
  • 51
    • 79951938429 scopus 로고    scopus 로고
    • Radiotherapy with concurrent carbogen and nicotinamide in bladder carcinoma
    • Hoskin PJ, Rojas AM, Bentzen SM, et al. Radiotherapy with concurrent carbogen and nicotinamide in bladder carcinoma. J Clin Oncol. 2010;28: 4912-4918
    • (2010) J Clin Oncol , vol.28 , pp. 4912-4918
    • Hoskin, P.J.1    Rojas, A.M.2    Bentzen, S.M.3
  • 52
    • 80051795366 scopus 로고    scopus 로고
    • Outcome after ARCON for clinical stage T2-4 laryngeal cancer: Early results of a phase III randomized trial
    • Kaanders J, Terhaard C, Doornaert P, et al. Outcome after ARCON for clinical stage T2-4 laryngeal cancer: Early results of a phase III randomized trial. Radiother Oncol. 2010;96(suppl 1):S158
    • (2010) Radiother Oncol , vol.96 , Issue.SUPPL. 1
    • Kaanders, J.1    Terhaard, C.2    Doornaert, P.3
  • 53
    • 84864003904 scopus 로고    scopus 로고
    • Accelerated radiotherapy with carbogen and nicotinamide for laryngeal cancer: Results of a phase III randomized trial
    • Janssens GO, Rademakers SE, Terhaard CH, et al. Accelerated radiotherapy with carbogen and nicotinamide for laryngeal cancer: Results of a phase III randomized trial. J Clin Oncol. 2012;30:1777-1783
    • (2012) J Clin Oncol , vol.30 , pp. 1777-1783
    • Janssens, G.O.1    Rademakers, S.E.2    Terhaard, C.H.3
  • 54
    • 77954600498 scopus 로고    scopus 로고
    • Tirapazamine, cisplatin, and radiation versus cisplatin and radiation for advanced squamous cell carcinoma of the head and neck (TROG 02.02, HeadSTART): A phase III trial of the transtasman radiation oncology group
    • Rischin D, Peters LJ, O'Sullivan B, et al. Tirapazamine, cisplatin, and radiation versus cisplatin and radiation for advanced squamous cell carcinoma of the head and neck (TROG 02.02, HeadSTART): A phase III trial of the transtasman radiation oncology group. J Clin Oncol. 2010;28:2989-2995
    • (2010) J Clin Oncol , vol.28 , pp. 2989-2995
    • Rischin, D.1    Peters, L.J.2    O'Sullivan, B.3
  • 55
    • 34347259579 scopus 로고    scopus 로고
    • The hypoxic tumour microenvironment, patient selection and hypoxia-modifying treatments
    • Hoogsteen IJ, Marres HA, van der Kogel AJ, et al. The hypoxic tumour microenvironment, patient selection and hypoxia-modifying treatments. Clin Oncol (R Coll Radiol). 2007;19:385-396
    • (2007) Clin Oncol (R Coll Radiol , vol.19 , pp. 385-396
    • Hoogsteen, I.J.1    Marres, H.A.2    Van Der Kogel, A.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.