Paeoniflorin abrogates DSS-induced colitis via a TLR4-dependent pathway

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 306, Issue 1, 2014, Pages

  Zhang, Jingjing ^a,b   Dou, Wei ^a,c   Zhang, Eryun ^a,b   Sun, Aning ^a,b   Ding, Lili ^a   Wei, Xiaohui ^a   Chou, Guixin ^d   Mani, Sridhar ^c   Wang, Zhengtao ^a,b,d  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b CHINA PHARMACEUTICAL UNIVERSITY   (China)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^d Shanghai R and D Centre for Standardization of Traditional Chinese Medicine   (China)

Author keywords

DSS induced colitis; MAPK; NF B; Paeoniflorin; TLR4

Indexed keywords

CYCLOOXYGENASE 2; DEXTRAN SULFATE; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 6; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; MYELOPEROXIDASE; PAEONIFLORIN; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL; COLON CANCER; CONTROLLED STUDY; CYTOKINE PRODUCTION; DEXTRAN SODIUM SULFATE-INDUCED COLITIS; DRUG MECHANISM; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN CELL; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION; TRANSIENT TRANSFECTION;

DSS-INDUCED COLITIS; MAPK; NF-ΚB; PAEONIFLORIN; TLR4;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BENZOATES; BIOLOGICAL AVAILABILITY; BRIDGED COMPOUNDS; COLITIS; DEXTRAN SULFATE; DRUGS, CHINESE HERBAL; GENE EXPRESSION PROFILING; GLUCOSIDES; HT29 CELLS; HUMANS; INFLAMMATION; INTERLEUKIN-6; MAP KINASE SIGNALING SYSTEM; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, ANIMAL; NF-KAPPA B; PAEONIA; PEROXIDASE; PROTEIN BIOSYNTHESIS; TOLL-LIKE RECEPTOR 4; TRANSCRIPTIONAL ACTIVATION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84891547049     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00465.2012     Document Type: Article

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