Corneal stromal cell plasticity: In vitro regulation of cell phenotype through cell-cell interactions in a three-dimensional model

Tissue Engineering - Part A

Volumn 20, Issue 1-2, 2014, Pages 225-238

  Wilson, Samantha L ^a   Yang, Ying ^a   El Haj, Alicia J ^a  

^a KEELE UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; FIBROBLASTS; OPTICAL TOMOGRAPHY;

BIOLOGICAL PROPERTIES; CELL-CELL INTERACTION; CORNEAL STROMAL CELLS; ELASTIC MODULUS MEASUREMENTS; NON-DESTRUCTIVE TECHNIQUE; SPHERICAL INDENTATIONS; THREE-DIMENSIONAL MODEL; TRANSFORMING GROWTH FACTORS;

COHERENT LIGHT;

COLLAGEN TYPE 1; TRANSFORMING GROWTH FACTOR BETA1; WORTMANNIN;

ADULT; ANIMAL CELL; ARTICLE; CELL ACTIVATION; CELL CULTURE; CELL DIFFERENTIATION; CELL ENCAPSULATION; CELL FUNCTION; CELL INTERACTION; CELL LINEAGE; CELL STRUCTURE; CELL VIABILITY; COCULTURE; CONTROLLED STUDY; CORNEA CELL; CORNEA EPITHELIUM; CORNEA INJURY; CORNEA STROMA; CULTURE MEDIUM; EPITHELIUM CELL; EXPLANT; FIBROBLAST; FILTERS AND MEMBRANES; HUMAN; HUMAN CELL; HYDROGEL; IN VITRO STUDY; NONHUMAN; OPTICAL COHERENCE TOMOGRAPHY; PHENOTYPE; PHENOTYPIC PLASTICITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL EXPANSION; SUPPLEMENTATION; SWINE; YOUNG MODULUS;

ADULT; ANDROSTADIENES; BIOLOGICAL MARKERS; CELL COMMUNICATION; CELL DIFFERENTIATION; CELL SURVIVAL; CELLS, CULTURED; COCULTURE TECHNIQUES; CORNEAL STROMA; ELASTIC MODULUS; EPITHELIAL CELLS; FIBROBLASTS; HUMANS; KERATIN-3; MODELS, BIOLOGICAL; PHENOTYPE; STROMAL CELLS; TISSUE SCAFFOLDS; TRANSFORMING GROWTH FACTOR BETA1; VIMENTIN;

EID: 84891530352     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2013.0167     Document Type: Article

References (36)

1. Wilson, S.E., Liu, J.J., and Mohan, R.R. Stromal-epithelial interactions in the cornea. Prog Retin Eye Res 18, 293, 1999.
2. Du, Y., SundarRaj, N., Funderburgh, M.L., Harvey, S.A., Birk, D.E., and Funderburgh, J.L. Secretion and organization of a cornea-like tissue in vitro by stem cells from human corneal stroma. Invest Ophthalmol Vis Sci 48, 5038, 2007.
3. Espana, E.M., Kawakita, T., Di Pascuale, M.A., Li, W., Yeh, L.K., Parel, J.M., et al. The heterogeneous murine corneal stromal cell populations in vitro. Invest Ophthalmol Vis Sci 46, 4528, 2005.
4. Wilson, S.E., Netto, M., and Ambrósio, R., Jr. Corneal cells: chatty in development, homeostasis, wound healing, and disease. Am J Ophthalmol 136, 530, 2003.
5. Tuft, S.J., Gartry, D.S., Rawe, I.M., and Meek, K.M. Photorefractive keratectomy - implications of corneal woundhealing. Br J Ophthalmol 77, 243, 1993.
6. Nakamura, K., Kurosaka, D., Yoshino, M., Oshima, T., and Kurosaka, H. Injured corneal epithelial cells promote myodifferentiation of corneal fibroblasts. Invest Ophthalmol Vis Sci 43, 2603, 2002.
7. Fini, M.E., and Stramer, B.M. How the cornea heals: corneaspecific repair mechanisms affecting surgical outcomes. Cornea 24, 2, 2005.
8. Jester, J.V., and Jin, H.C. Modulation of cultured corneal keratocyte phenotype by growth factors/cytokines control in vitro contractility and extracellular matrix contraction. Exp Eye Res 77, 581, 2003.
9. Musselmann, K., Alexandrou, B., Kane, B., and Hassell, J.R. Maintenance of the keratocyte phenotype during cell proliferation stimulated by insulin. J Biol Chem 280, 32634, 2005.
10. Nishimura, T., Toda, S., Mitsumoto, T., Oono, S., and Sugihara, H. Effects of hepatocyte growth factor, transforming growth factor-beta 1 and epidermal growth factor on bovine corneal epithelial cells under epithelial-keratocyte interaction in reconstruction culture. Exp Eye Res 66, 105, 1998.
11. Dayhaw-Barker, P. Corneal wound healing: I. The players. Int Contact Lens Clin 22, 105, 1995.
12. Ahearne, M., Yang, Y., Then, K.Y., and Liu, K.K. Nondestructive mechanical characterisation of UVA/riboflavin crosslinked collagen hydrogels. Br J Ophthalmol 92, 268, 2008.
13. Yang, Y., Dubois, A., Qin, X.P., Li, J., El Haj, A.J., and Wang, R.K. Investigation of optical coherence tomography as an imaging modality in tissue engineering. Phys Med Biol 51, 1649, 2006.
14. Wilson, S.L., Wimpenny, I., Ahearne, M., Rauz, S., El Haj, A.J., and Yang, Y. Chemical and topographical effects on cell differentiation and matrix elasticity in a corneal stromal layer model. Adv Funct Mater 22, 3641, 2012.
15. Ahearne, M., Yang, Y., El Haj, A.J., Then, K.Y., and Liu, K.K. Characterizing the viscoelastic properties of thin hydrogelbased constructs for tissue engineering applications. J R Soc Interface 2, 455, 2005.
16. Ahearne, M., Wilson, S.L., Liu, K.K., Rauz, S., El Haj, A.J., and Yang, Y. Influence of cell and collagen concentration on the cell-matrix mechanical relationship in a corneal stroma wound healing model. Exp Eye Res 91, 584, 2010.
17. Ju, B.F., and Liu, K.K. Characterizing viscoelastic properties of thin elastomeric membrane. Mech Mater 34, 485, 2002.
18. Liu, K.K., and Ju, B.F. A novel technique for mechanical characterization of thin elastomeric membrane. J Phys DAppl Phys 34, 91, 2001.
19. Mi, S., Chen, B., Wright, B., and Connon, C.J. Ex vivo construction of an artificial ocular surface by combination of corneal limbal epithelial cells and a compressed collagen scaffold containing keratocytes. Tissue Eng Part A 16, 2091, 2010.
20. Pang, K., Du, L., and Wu, X. A rabbit anterior cornea replacement derived from acellular porcine cornea matrix, epithelial cells and keratocytes. Biomaterials 31, 7257, 2010.
21. Lu, L., Reinach, P.S., and Kao, W.W.Y. Corneal epithelial wound healing. Exp Biol Med 226, 653, 2001.
22. Pei, Y., Reins, R.Y., and McDermott, A.M. Aldehyde dehydrogenase (ALDH) 3A1 expression by the human keratocyte and its repair phenotypes. Exp Eye Res 83, 1063, 2006.
23. Berryhill, B.L., Kader, R., Kane, B., Birk, D.E., Teng, J., and Hassell, A.R. Partial restoration of the keratocyte phenotype to bovine keratocytes made fibroblastic by serum. Invest Ophthalmol Vis Sci 43, 3416, 2002.
24. Kim, A., Zhou, C., Lakshman, N., and Petrol, W.M. Corneal stromal cells use both high- and low-contractility migration mechanisms in 3-D collagen matrices. Exp Cell Res 318, 741, 2012.
25. Suzuki, K., Saito, J., Yanai, R., Yamada, N., Chikama, T., Seki, K., et al. Cell-matrix, and cell-cell interactions during corneal epithelial wound healing. Prog Retin Eye Res 22, 113, 2003.
26. Agrawal, V.B., and Tsai, R.J.F. Corneal epithelial wound healing. Indian J Ophthalmol 51, 5, 2003.
27. Wilson, S.L., El Haj, A.J., and Yang, Y. Control of scar tissue formation in the cornea: strategies in clinical and corneal tissue engineering. J Funct Biomater 3, 642, 2012.
28. Chandrasekher, G., and Bazan, H.E.P. Corneal epithelial wound healing increases the expression but not long lasting activation of the p85 alpha subunit of phosphatidylinositol-3 kinase. Curr Eye Res 18, 168, 1999.
29. Lyu, J., Lee, K.S., and Joo, C.K. Transactivation of EGFR mediates insulin-stimulated ERK1/2 activation and enhanced cell migration in human corneal epithelial cells. Mol Vis 12, 1403, 2006.
30. Zhang, Y., Liou, G.I., Gulati, A.K., and Akhtar, R.A. Expression of phosphatidylinositol 3-kinase during EGF-stimulated wound repair in rabbit corneal epithelium. Invest Ophthalmol Vis Sci 40, 2819, 1999.
31. Islam, M., and Akhtar, R.A. Upregulation of phospholipase C gamma 1 activity during EGF-induced proliferation of corneal epithelial cells: effect of phosphoinositide-3 kinase. Invest Ophthalmol Vis Sci 42, 1472, 2001.
32. Kakazu, A., Chandrasekher, G., and Bazan, H.E.P. HGF protects corneal epithelial cells from apoptosis by the PI-3K/ Akt-1/bad- but not the ERK1/2-mediated signaling pathway. Invest Ophthalmol Vis Sci 45, 3485, 2004.
33. Dayhaw-Barker, P. Corneal wound healing: II. The process. Int Contact Lens Clin 22, 110, 1995.
34. West-Mays, J.A., and Dwivedi, D.J. The keratocyte: corneal stromal cell with variable repair phenotypes. Int J Biochem Cell Biol 38, 1625, 2006.
35. Imanishi, J., Kamiyama, K., Iguchi, I., Kita, M., Sotozono, C., and Kinoshita, S. Growth factors: importance in wound healing and maintenance of transparency of the cornea. Prog Retin Eye Res 19, 113, 2000.
36. Karamichos, D., Hutcheon, A.E.K., and Zieske, J.D. Transforming growth factor-beta 3 regulates assembly of a nonfibrotic matrix in a 3D corneal model. J Tissue Eng Regen Med 5, 228, 2011.