Ex vivo construction of an artificial ocular surface by combination of corneal limbal epithelial cells and a compressed collagen scaffold containing keratocytes

Tissue Engineering - Part A

Volumn 16, Issue 6, 2010, Pages 2091-2100

  Mi, Shengli ^a   Chen, Bo ^a   Wright, Bernice ^a   Connon, Che J ^a  

^a UNIVERSITY OF READING   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; COLLAGEN; POLYMERASE CHAIN REACTION; SCAFFOLDS; SCANNING ELECTRON MICROSCOPY; STEM CELLS; TISSUE;

AMNIOTIC MEMBRANES; CELL MORPHOLOGY; COLLAGEN GELS; COLLAGEN SCAFFOLDS; CORNEAL FIBROBLASTS; EPITHELIAL CELLS; EX-VIVO; KERATOCYTES; LAMININ; MRNA EXPRESSION LEVEL; PROTEIN EXPRESSION PROFILES; REAL-TIME POLYMERASE CHAIN REACTION; STRATIFIED LAYERS;

GELS;

COLLAGEN; CYTOKERATIN 12; CYTOKERATIN 14; CYTOKERATIN 3; TISSUE SCAFFOLD;

ANIMAL; ARTICLE; CATTLE; CELL CULTURE; CHEMISTRY; CORNEA LIMBUS; CYTOLOGY; EPITHELIUM CELL; FIBROBLAST; GENETICS; IMMUNOHISTOCHEMISTRY; METABOLISM; METHODOLOGY; POLYMERASE CHAIN REACTION; SCANNING ELECTRON MICROSCOPY; TISSUE ENGINEERING; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CATTLE; CELLS, CULTURED; COLLAGEN; EPITHELIAL CELLS; FIBROBLASTS; IMMUNOHISTOCHEMISTRY; KERATIN-12; KERATIN-14; KERATIN-3; LIMBUS CORNEAE; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, ELECTRON, TRANSMISSION; POLYMERASE CHAIN REACTION; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 77953339581     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2009.0748     Document Type: Article

References (52)

1. Shengli, M., Xueyi,Y., Qingmei, Z., Lei, Q., Shuming, C., Keith, M., and Zhongying, D. Reconstruction of corneal epithelium with cryopreserved corneal limbal stem cells in a goat model. Mol Reprod Dev 75, 1607, 2008.
2. Lei, Q., Xueyi, Y., Xin, W., Ming, Z., Shengli, M., and Zhongying, D. Reconstruction of corneal epithelium with cryopreserved corneal limbal stem cells in rabbit model. Vet J 179, 392, 2009.
3. Xueyi, Y., Nicanor, I.M., Qingmei, Z., Shengli, M., Zhenhui, Z., Dan, C., and Zhongying, D. Reconstruction of damaged cornea by autologous transplantation of epidermal adult stem cells. Mol Vis 14, 1064, 2008.
4. Connon, C., Kawasaki, S., Liles, M., Koizumi, N., Yamasaki, K., Nakamura, T., Quantock, A.J., and Shigeru Kinoshita. Gene expression and immunolocalisation of a calcium activated chloride channel during the stratification of cultivated and developing corneal epithelium. Cell Tissue Res 323, 177, 2006.
5. Dua, H.S., Shanmuganathan, V.A., Powell, R.A.O., Tighe, P.J., and Joseph, A. Limbal epithelial crypts: a novel anatomical structure and a putative limbal stem cell niche. Br J Ophthalmol 89, 529, 2005.
6. Hopkinson, A., McIntosh, R.S., Tighe, P.J., James, D., and Dua, H.S. Amniotic membrane for ocular surface reconstruction: donor variations and the effect of handling on TGF-{beta} content. Invest Ophthalmol Vis Sci 47, 4316, 2006.
7. Connon, C.J., Takahiro, N., Andy, H., Andrew, Q., Naoto, Y., and James, D. The biomechanics of amnion rupture: an X-ray diffraction study. PLoS ONE 2, e1147, 2007.
8. Connon, C.J., Doutch, J., Chen, B., Hopkinson, A., Mehta, J.S., Nakamura, T., Kinoshita, S., and Meek, K.M. The variation in transparency Of amniotic membrane used in ocular surface regeneration. Br J Ophthalmol 19, 2009. doi:10.1136=bjo.2008.153064.
9. Schwab, I. Cultured corneal epithelia for ocular surface disease. Trans Am Ophthalmol Soc 97, 891, 1999.
10. Cen, L., Liu, W., Cui, L., Zhang, W., and Cao, Y. Collagen tissue engineering: development of novel biomaterials and applications. Pediatr Res 63, 492, 2008.
11. Duan, X., and Sheardown, H. Incorporation of cell-adhesion peptides into collagen scaffolds promotes cor-neal epithelial stratification. J Biomater Sci Polym Ed 18, 701, 2007.
12. Duan, X., and Sheardown, H. Dendrimer crosslinked collagen as a corneal tissue engineering scaffold: mechanical properties and corneal epithelial cell interactions. Bioma-terials 27, 4608, 2006.
13. Rama, P., Bonini, S., Lambiase, A., Golisano, O., Paterna, P., De Luca, M., and Pellegrini, G. Autologous fibrin-cultured limbal stem cells permanently restore the corneal surface of patients with total limbal stem cell deficiency. Transplantation 72, 1478, 2001.
14. Han, B., Schwab, I.R., Madsen, T.K., and Isseroff, R.R. A fibrin-based bioengineered ocular surface with human cor-neal epithelial stem cells. Cornea 21, 505, 2002.
15. Zhong, S., Teo, W.E., Zhu, X., Beuerman, R., Ramakrishna, S., and Yung, L.Y. Formation of collagen-glycosaminoglycan blended nanofibrous scaffolds and their biological properties. Biomacromolecules 6, 2998, 2005.
16. Zhu, X., Beuerman, R.W., Chan-Park, M.B., Cheng, Z., Ang, L.P., and Tan, D.T. Enhancement of the mechanical and biological properties of a biomembrane for tissue engineering the ocular surface. Ann Acad Med Singapore 35, 210, 2006.
17. Ang, L.P., Cheng, Z.Y., Beuerman, R.W., Teoh, S.H., Zhu, X., and Tan, D.T. The development of a serum-free derived bioengineered conjunctival epithelial equivalent using an ultrathin poly(epsilon-caprolactone) membrane substrate. Invest Ophthalmol Vis Sci 47, 105, 2006.
18. Di Girolamo, N., Chui, J., Wakefield, D., and Coroneo, M.T. Cultured human ocular surface epithelium on therapeutic contact lenses. Br J Ophthalmol 91, 459, 2007.
19. Sitalakshmi, G., Sudha, B., Madhavan, H.N., Vinay, S., Krishnakumar, S., Mori, Y., Yoshioka, H., and Abraham, S. Ex vivo cultivation of corneal limbal epithelial cells in a thermoreversible polymer (Mebiol gel) and their transplantation in rabbits: an animal model. Tissue Eng Part A 15, 407, 2009.
20. Chandran, P.L., and Barocas, V.H., Microstructural mechanics of collagen gels in confined compression: por-oelasticity, viscoelasticity and collapse. J Biomech Eng 126, 152, 2004.
21. Wan, J.L., Yi, J.J., and Rocky, S.T. Chondrocyte phenotype in engineered fibrous matrix is regulated by fiber size. Tissue Eng 12, 1775, 2006.
22. Li, G.N., Livi, L.L., Gourd, C.M., Deweerd, E.S., and Hoffman, K.D. Genomic and morphological changes of neuro-blastoma cells in response to three-dimensional matrices. Tissue Eng 13, 1035, 2007.
23. Shi, Y., Rittman, L., and Vesely, I. Novel geometries for tissue-engineered tendonous collagen constructs. Tissue Eng 12, 2601, 2006.
24. Bentley, E., Campbell, S., Woo, H.M., and Murphy, C.J. The effect of chronic corneal epithelial debridement on epithelial and stromal morphology in dogs. Invest Ophthalmol Vis Sci 43, 2136, 2002.
25. Taliana, L., Evans, M.D.M., Dimitrijevich, S.D., and Steele, J.G. The influence of stromal contraction in a wound model system on corneal epithelial stratification. Invest Ophthal-mol Vis Sci 42, 81, 2001.
26. Brown, R.A., Wiseman, M., Chuo, C.B., Cheema, U., and Nazhat, S.N. Ultrarapid engineering of biomimetic materials and tissues: fabrication of nano-and microstructures by PC. Adv Funct Mater 15, 1762, 2005.
27. Tatsuya, M., Shiro, A., Seiichi, Y., Saiko, U., Tomohiko, U., and Satoru, Y. Isolation and distribution of rabbit keratocyte precursors. Mol Vis 14, 197, 2008.
28. Tatsuya, M., Shiro, A., Seiichi, Y., Saiko, U., Satoru, Y., To-mohiko, U., Yu, K., and Yasuhiko, T. Tissue engineering of corneal stroma with rabbit fibroblast precursors and gelatin hydrogels. Mol Vis 14, 1819, 2008.
29. Jean, T.J., James, R.R., Jingjing, B., and Bryan, M.G. Corneal epithelial cell growth over tethered-protein=peptide surface-modified hydrogels. J Biomed Mater Res Part B: Appl Bio-mater 72B, 198, 2004.
30. Ahmad, S., Stewart, R., Yung, S., Kolli, S., Armstrong, L., Stojkovic, M., Figueiredo, F., and Lako, M. Differentiation of human embryonic stem cells into corneal epithelial-like cells by in vitro replication of the corneal epithelial stem cell niche. Stem Cell 25, 1145, 2007.
31. Nishida, K., Yamato, M., Hayashida, Y., Watanabe, K., Maeda, N., Watanabe, H., Yamamoto, K., Nagai, S., Kikuchi, A., Tano, Y., and Okano, T. Functional bioengineered cor-neal epithelial sheet grafts from corneal stem cells expanded ex vivo on a temperature-responsive cell culture surface. Transplantation 77, 379, 2004.
32. Malak, T.M., Ockleford, C.D., Bell, S.C., Dalgleish, R., Bright, N., and Macvicar, J. Confocal immunofluorescence localization of collagen types I, III, IV, V and VI and their ultra-structural organization in term human fetal membranes. Placenta 14, 385, 1993.
33. Ihanamaki, T., Pelliniemi, L.J., and Vuorio, E. Collagens and collagen-related matrix components in the human and mouse eye. Prog Retin Eye Res 23, 403, 2004.
34. Lia, F., Griffitha, M., Lib, Z., Tanodekaewb, S., Sheardownd, H., and Hakim, M. Recruitment of multiple cell lines by collagen-synthetic copolymer matrices in corneal regeneration. Biomaterial 26, 3093, 2005.
35. Yuwen, L., Lisha, G., David, J.C., Fagerholm, P., Lagali, N., and Mitchell, A.W. A simple cross-linked collagen tissue substitute for corneal implantation. Invest Ophthalmol Vis Sci 47, 1869, 2006.
36. Xiaodong, D., Christopher, M., May, G., and Heather, S. Biofunctionalization of collagen for improved biological response: scaffolds for corneal tissue engineering. Biomaterials 28, 78, 2007.
37. Berglund, J.D., Nerem, R.M., and Sambanis, A. Incorporation of intact elastin scaffolds in tissue-engineered collagen-based vascular grafts. Tissue Eng 10, 1526, 2004.
38. Charulatha, V., and Rajaram, A. Influence of different crosslinking treatments on the physical properties of collagen membranes. Biomaterials 24, 759, 2003.
39. Koob, T.J., and Hernandez, D.J. Material properties of polymerized NDGA-collagen composite fibers: development of biologically based tendon constructs. Biomaterials 23, 203, 2002.
40. Park, S.N., Park, J.C., Kim, H.O., Song, M.J., and Suh, H. Characterization of porous collagen=hyaluronic acid scaffold modified by 1-ethyl-3-(3-dimethylaminopropyl) carbodii-mide cross-linking. Biomaterials 23, 1205, 2002.
41. Elbjeirami, W.M., Yonter, E.O., Starcher, B.C., and West, J.L. Enhancing mechanical properties of tissue-engineered constructs via lysyl oxidase crosslinking activity. J. Biomed Mater Res Part A 66, 513, 2003.
42. Gregor W. Crosslinking treatment of progressive kera-toconus: new hope. Curr Opin Ophthalmol 17, 356, 2006
43. Wollensak, G., Spoerl, E., Reber, F., and Seiler, T. Keratocyte cytotoxicity of riboflavin=UVA-treatment in vitro. Eye 18, 718, 2004.
44. Wollensak, G., Spoerl, E., Reber, F., Pillunat, L., and Funk, R. Corneal endothelial cytotoxicity of riboflavin=UVA treatment in vitro. Ophthalmic Res 35, 324, 2003.
45. Ambach, W., Blumthaler, M., Schopf, T., Ambach, E., Katzgraber, F., Daxecker, F., and Daxer, A. Spectral transmission of the optical media of the human eye with respect to keratitis and cataract formation. Doc Ophthalmol 88, 165, 1994.
46. Spoerl, E., Mrochen, M., Sliney, D., Trokel, S., and Seiler, T. Safety of UVA-riboflavin cross-linking of the cornea. Cornea 26, 385, 2007.
47. Dijkstra, P.J., Damink, L.H.H.O., and Feijen, J. Chemical stabilization of collagen based biomaterials. Cardiovasc Pa-thol 5, 295, 1996.
48. Dowd, C.J., Cooney, C.L., and Nugent, M.A. Heparan sul-fate mediates bFGF transport through basement membrane by diffusion with rapid reversible binding. J Biol Chem 274, 5236, 1999.
49. Gabison, E.E., Huet, E., Baudouin, C., and Menashi, S. Direct epithelial-stromal interaction in corneal wound healing: Role of EMMPRIN=CD147 in MMPs induction and beyond. Prog Retin Eye Res 28, 19, 2009.
50. Dabin, I., and Courtois, Y. In vitro kinetics of basic fibroblast growth factor diffusion across a reconstituted corneal en-dothelium. J Cell Physiol 147, 396, 1991.
51. Ivan, R.S., Nigel, T.J., and Damien, G.H. Inherent risks associated with manufacture of bioengineered ocular surface tissue. Arch Ophthalmol 124, 1734, 2006.
52. Gomes, J.A., Romano, A., Santos, M.S., and Dua, H.S. Am-niotic membrane use in ophthalmology. Curr Opin Oph-thalmol 16, 233, 2005.