메뉴 건너뛰기




Volumn 3, Issue 2, 2012, Pages 161-173

Keratin function and regulation in tissue homeostasis and pathogenesis

Author keywords

cell growth; keratins; posttranslational modification; protein biosynthesis; stress response

Indexed keywords


EID: 84891501261     PISSN: 18685021     EISSN: 1868503X     Source Type: Journal    
DOI: 10.1515/bmc.2011.060     Document Type: Review
Times cited : (6)

References (81)
  • 1
    • 33846307476 scopus 로고    scopus 로고
    • Keratin function in skin epithelia: A broadening palette with surprising shades
    • Gu LH, Coulombe PA. Keratin function in skin epithelia: a broadening palette with surprising shades. Curr Opin Cell Biol 2007; 19: 13-23.
    • (2007) Curr Opin Cell Biol , vol.19 , pp. 13-23
    • Gu, L.H.1    Coulombe, P.A.2
  • 2
    • 34249723830 scopus 로고    scopus 로고
    • Structural and regulatory functions of keratins
    • Magin TM, Vijayaraj P, Leube RE. Structural and regulatory functions of keratins. Exp Cell Res 2007; 313: 2021-32.
    • (2007) Exp Cell Res , vol.313 , pp. 2021-2032
    • Magin, T.M.1    Vijayaraj, P.2    Leube, R.E.3
  • 3
    • 44149099717 scopus 로고    scopus 로고
    • The human keratins: Biology and pathology
    • Moll R, Divo M, Langbein L. The human keratins: biology and pathology. Histochem Cell Biol 2008; 129: 705-33.
    • (2008) Histochem Cell Biol , vol.129 , pp. 705-733
    • Moll, R.1    Divo, M.2    Langbein, L.3
  • 4
    • 68849111162 scopus 로고    scopus 로고
    • Toward unraveling the complexity of simple epithelial keratins in human disease
    • Omary MB, Ku NO, Strnad P, Hanada S. Toward unraveling the complexity of simple epithelial keratins in human disease. J Clin Invest 2009; 119: 1794-805.
    • (2009) J Clin Invest , vol.119 , pp. 1794-1805
    • Omary, M.B.1    Ku, N.O.2    Strnad, P.3    Hanada, S.4
  • 5
    • 78651397689 scopus 로고    scopus 로고
    • Keratins in health and cancer: More than mere epithelial cell markers
    • Karantza V. Keratins in health and cancer: more than mere epithelial cell markers. Oncogene 2011; 30: 127-38.
    • (2011) Oncogene , vol.30 , pp. 127-138
    • Karantza, V.1
  • 7
    • 68549090936 scopus 로고    scopus 로고
    • Self-organization of keratin intermediate filaments into cross-linked networks
    • Lee CH, Coulombe PA. Self-organization of keratin intermediate filaments into cross-linked networks. J Cell Biol 2009; 186: 409-21.
    • (2009) J Cell Biol , vol.186 , pp. 409-421
    • Lee, C.H.1    Coulombe, P.A.2
  • 8
    • 0032559341 scopus 로고    scopus 로고
    • A structural scaffolding of intermediate filaments in health and disease
    • Fuchs E, Cleveland DW. A structural scaffolding of intermediate filaments in health and disease. Science 1998; 279: 514-9.
    • (1998) Science , vol.279 , pp. 514-519
    • Fuchs, E.1    Cleveland, D.W.2
  • 10
    • 0022348539 scopus 로고
    • Pair formation and promiscuity of cytokeratins: Formation in vitro of heterotypic complexes and intermediate-sized filaments by homologous and heterologous recombinations of purified polypeptides
    • Hatzfeld M, Franke WW. Pair formation and promiscuity of cytokeratins: formation in vitro of heterotypic complexes and intermediate-sized filaments by homologous and heterologous recombinations of purified polypeptides. J Cell Biol 1985; 101(5 Pt 1): 1826-41.
    • (1985) J Cell Biol , vol.101 , Issue.5 , pp. 1826-1841
    • Hatzfeld, M.1    Franke, W.W.2
  • 11
    • 78449250631 scopus 로고    scopus 로고
    • Against the rules: Human keratin K80: Two functional alternative splice variants, K80 and K80.1, with special cellular localization in a wide range of epithelia
    • Langbein L, Eckhart L, Rogers MA, Praetzel-Wunder S, Schweizer J. Against the rules: human keratin K80: two functional alternative splice variants, K80 and K80.1, with special cellular localization in a wide range of epithelia. J Biol Chem 2010; 285: 36909-21.
    • (2010) J Biol Chem , vol.285 , pp. 36909-36921
    • Langbein, L.1    Eckhart, L.2    Rogers, M.A.3    Praetzel-Wunder, S.4    Schweizer, J.5
  • 14
  • 15
    • 43249087287 scopus 로고    scopus 로고
    • Vibrissa hair bulge houses two populations of skin epithelial stem cells distinct by their keratin profile
    • Larouche D, Tong X, Fradette J, Coulombe PA, Germain L. Vibrissa hair bulge houses two populations of skin epithelial stem cells distinct by their keratin profile. FASEB J 2008; 22: 1404-15.
    • (2008) FASEB J , vol.22 , pp. 1404-1415
    • Larouche, D.1    Tong, X.2    Fradette, J.3    Coulombe, P.A.4    Germain, L.5
  • 16
    • 6344280832 scopus 로고    scopus 로고
    • Emerging functions: Diseases and animal models reshape our view of the cytoskeleton
    • Magin TM, Reichelt J, Hatzfeld M. Emerging functions: diseases and animal models reshape our view of the cytoskeleton. Exp Cell Res 2004; 301: 91-102.
    • (2004) Exp Cell Res , vol.301 , pp. 91-102
    • Magin, T.M.1    Reichelt, J.2    Hatzfeld, M.3
  • 17
    • 17144371855 scopus 로고    scopus 로고
    • The cornified envelope: A model of cell death in the skin
    • Candi E, Schmidt R, Melino G. The cornified envelope: a model of cell death in the skin. Nat Rev Mol Cell Biol 2005; 6: 328-40.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 328-340
    • Candi, E.1    Schmidt, R.2    Melino, G.3
  • 19
    • 0242298585 scopus 로고    scopus 로고
    • Loss of keratin 6 (K6) proteins reveals a function for intermediate filaments during wound repair
    • Wong P, Coulombe PA. Loss of keratin 6 (K6) proteins reveals a function for intermediate filaments during wound repair. J Cell Biol 2003; 163: 327-37.
    • (2003) J Cell Biol , vol.163 , pp. 327-337
    • Wong, P.1    Coulombe, P.A.2
  • 20
    • 33745003902 scopus 로고    scopus 로고
    • A keratin cytoskeletal protein regulates protein synthesis and epithelial cell growth
    • Kim S, Wong P, Coulombe PA. A keratin cytoskeletal protein regulates protein synthesis and epithelial cell growth. Nature 2006; 441: 362-5.
    • (2006) Nature , vol.441 , pp. 362-365
    • Kim, S.1    Wong, P.2    Coulombe, P.A.3
  • 21
    • 35448991707 scopus 로고    scopus 로고
    • Reprogramming of keratin biosynthesis by sul-foraphane restores skin integrity in epidermolysis bullosa simplex
    • Kerns ML, Depianto D, Dinkova-Kostova AT, Talalay P, Coulombe PA. Reprogramming of keratin biosynthesis by sul-foraphane restores skin integrity in epidermolysis bullosa simplex. Proc Natl Acad Sci USA 2007; 104: 14460-5.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 14460-14465
    • Kerns, M.L.1    Depianto, D.2    Dinkova-Kostova, A.T.3    Talalay, P.4    Coulombe, P.A.5
  • 22
    • 77953012548 scopus 로고    scopus 로고
    • Stress-activated cap'n'collar transcription factors in aging and human disease
    • Sykiotis GP, Bohmann D. Stress-activated cap'n'collar transcription factors in aging and human disease. Sci Signal 2010; 3: re3.
    • (2010) Sci Signal , vol.3 , pp. re3
    • Sykiotis, G.P.1    Bohmann, D.2
  • 23
    • 78650116927 scopus 로고    scopus 로고
    • Differential modulation of keratin expression by sulforaphane occurs via Nrf2-dependent and-independent pathways in skin epithelia
    • Kerns M, Depianto D, Yamamoto M, Coulombe PA. Differential modulation of keratin expression by sulforaphane occurs via Nrf2-dependent and-independent pathways in skin epithelia. Mol Biol Cell 2010; 21: 4068-75.
    • (2010) Mol Biol Cell , vol.21 , pp. 4068-4075
    • Kerns, M.1    Depianto, D.2    Yamamoto, M.3    Coulombe, P.A.4
  • 24
    • 72149095755 scopus 로고    scopus 로고
    • Eukaryotic stress granules: The ins and outs of translation
    • Buchan JR, Parker R. Eukaryotic stress granules: the ins and outs of translation. Mol Cell 2009; 36: 932-41.
    • (2009) Mol Cell , vol.36 , pp. 932-941
    • Buchan, J.R.1    Parker, R.2
  • 25
    • 79954416526 scopus 로고    scopus 로고
    • The cytoprotective role of the Keap1-Nrf2 pathway
    • Baird L, Dinkova-Kostova AT. The cytoprotective role of the Keap1-Nrf2 pathway. Arch Toxicol 2011; 85: 241-72.
    • (2011) Arch Toxicol , vol.85 , pp. 241-272
    • Baird, L.1    Dinkova-Kostova, A.T.2
  • 27
    • 85129448484 scopus 로고    scopus 로고
    • The role of keratins in epithelial homeostasis
    • Peter M. Elias, Kenneth R. Feingold, editors New York: Taylor & Francis
    • Magin TM, Reichelt J, Chen J. The role of keratins in epithelial homeostasis. In: Peter M. Elias, Kenneth R. Feingold, editors. Skin barrier. New York: Taylor & Francis, 2006: pp. 141-70.
    • (2006) Skin Barrier , pp. 141-170
    • Magin, T.M.1    Reichelt, J.2    Chen, J.3
  • 28
    • 0024208213 scopus 로고
    • Low level expression of cytok-eratins 8, 18 and 19 in vascular smooth muscle cells of human umbilical cord and in cultured cells derived therefrom, with an analysis of the chromosomal locus containing the cytokeratin 19 gene
    • Bader BL, Jahn L, Franke WW. Low level expression of cytok-eratins 8, 18 and 19 in vascular smooth muscle cells of human umbilical cord and in cultured cells derived therefrom, with an analysis of the chromosomal locus containing the cytokeratin 19 gene. Eur J Cell Biol 1988; 47: 300-19.
    • (1988) Eur J Cell Biol , vol.47 , pp. 300-319
    • Bader, B.L.1    Jahn, L.2    Franke, W.W.3
  • 29
    • 0023787238 scopus 로고
    • Transient coexpression of desmin and cytokeratins 8 and 18 in developing myocardial cells of some vertebrate species
    • Kuruc N, Franke WW. Transient coexpression of desmin and cytokeratins 8 and 18 in developing myocardial cells of some vertebrate species. Differentiation 1988; 38: 177-93.
    • (1988) Differentiation , vol.38 , pp. 177-193
    • Kuruc, N.1    Franke, W.W.2
  • 30
    • 24344453799 scopus 로고    scopus 로고
    • Specific interaction of the actin-binding domain of dystrophin with intermediate filaments containing keratin 19
    • Stone MR, O'Neill A, Catino D, Bloch RJ. Specific interaction of the actin-binding domain of dystrophin with intermediate filaments containing keratin 19. Mol Biol Cell 2005; 16: 4280-93.
    • (2005) Mol Biol Cell , vol.16 , pp. 4280-4293
    • Stone, M.R.1    O'Neill, A.2    Catino, D.3    Bloch, R.J.4
  • 32
    • 79955130118 scopus 로고    scopus 로고
    • Physiology, structure, and susceptibility to injury of skeletal muscle in mice lacking keratin 19-based and desmin-based intermediate filaments
    • Lovering RM, O'Neill A, Muriel JM, Prosser BL, Strong J, Bloch RJ. Physiology, structure, and susceptibility to injury of skeletal muscle in mice lacking keratin 19-based and desmin-based intermediate filaments. Am J Physiol Cell Physiol 2011; 300: C803-13.
    • (2011) Am J Physiol Cell Physiol , vol.300 , pp. C803-C813
    • Lovering, R.M.1    O'Neill, A.2    Muriel, J.M.3    Prosser, B.L.4    Strong, J.5    Bloch, R.J.6
  • 33
    • 78751534200 scopus 로고    scopus 로고
    • Keratin hypersumoylation alters filament dynamics and is a marker for human liver disease and keratin mutation
    • Snider NT, Weerasinghe S V, Iniguez-Lluhi JA, Herrmann H, Omary MB. Keratin hypersumoylation alters filament dynamics and is a marker for human liver disease and keratin mutation. J Biol Chem 2011; 286: 2273-84.
    • (2011) J Biol Chem , vol.286 , pp. 2273-2284
    • Snider, N.T.1    Weerasinghe, S.V.2    Iniguez-Lluhi, J.A.3    Herrmann, H.4    Omary, M.B.5
  • 34
    • 33745628320 scopus 로고    scopus 로고
    • A disease-and phosphorylation-related nonmechanical function for keratin 8
    • Ku NO, Omary MB. A disease-and phosphorylation-related nonmechanical function for keratin 8. J Cell Biol 2006; 174: 115-25.
    • (2006) J Cell Biol , vol.174 , pp. 115-125
    • Ku, N.O.1    Omary, M.B.2
  • 36
    • 0037007011 scopus 로고    scopus 로고
    • Keratin binding to 14-3-3 proteins modulates keratin filaments and hepatocyte mitotic progression
    • Ku NO, Michie S, Resurreccion EZ, Broome RL, Omary MB. Keratin binding to 14-3-3 proteins modulates keratin filaments and hepatocyte mitotic progression. Proc Natl Acad Sci USA 2002; 99: 4373-8.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 4373-4378
    • Ku, N.O.1    Michie, S.2    Resurreccion, E.Z.3    Broome, R.L.4    Omary, M.B.5
  • 37
    • 24044510445 scopus 로고    scopus 로고
    • Keratin 8 phosphoryla-tion by protein kinase C delta regulates shear stress-mediated disassembly of keratin intermediate filaments in alveolar epithelial cells
    • Ridge KM, Linz L, Flitney FW, Kuczmarski ER, Chou YH, Omary MB, Sznajder JL, Goldman RD. Keratin 8 phosphoryla-tion by protein kinase C delta regulates shear stress-mediated disassembly of keratin intermediate filaments in alveolar epithelial cells. J Biol Chem 2005; 280: 30400-5.
    • (2005) J Biol Chem , vol.280 , pp. 30400-30405
    • Ridge, K.M.1    Linz, L.2    Flitney, F.W.3    Kuczmarski, E.R.4    Chou, Y.H.5    Omary, M.B.6    Sznajder, J.L.7    Goldman, R.D.8
  • 38
    • 34249903066 scopus 로고    scopus 로고
    • P38 MAPK-dependent shaping of the keratin cytoskeleton in cultured cells
    • Woll S, Windoffer R, Leube RE. p38 MAPK-dependent shaping of the keratin cytoskeleton in cultured cells. J Cell Biol 2007; 177: 795-807.
    • (2007) J Cell Biol , vol.177 , pp. 795-807
    • Woll, S.1    Windoffer, R.2    Leube, R.E.3
  • 39
    • 0032055050 scopus 로고    scopus 로고
    • Phosphorylation of human keratin 18 serine 33 regulates binding to 14-3-3 proteins
    • Ku NO, Liao J, Omary MB. Phosphorylation of human keratin 18 serine 33 regulates binding to 14-3-3 proteins. EMBO J 1998; 17: 1892-906.
    • (1998) EMBO J , vol.17 , pp. 1892-1906
    • Ku, N.O.1    Liao, J.2    Omary, M.B.3
  • 40
    • 54449101873 scopus 로고    scopus 로고
    • Ubiquitin-proteasome-mediated degradation of keratin intermediate filaments in mechanically stimulated A549 cells
    • Jaitovich A, Mehta S, Na N, Ciechanover A, Goldman RD, Ridge KM. Ubiquitin-proteasome-mediated degradation of keratin intermediate filaments in mechanically stimulated A549 cells. J Biol Chem 2008; 283: 25348-55.
    • (2008) J Biol Chem , vol.283 , pp. 25348-25355
    • Jaitovich, A.1    Mehta, S.2    Na, N.3    Ciechanover, A.4    Goldman, R.D.5    Ridge, K.M.6
  • 41
    • 80052624717 scopus 로고    scopus 로고
    • Cytoskeleton in motion: The dynamics of keratin intermediate filaments in epithe-lia
    • Windoffer R, Beil M, Magin TM, Leube RE. Cytoskeleton in motion: the dynamics of keratin intermediate filaments in epithe-lia. J Cell Biol 2011; 194: 669-78.
    • (2011) J Cell Biol , vol.194 , pp. 669-678
    • Windoffer, R.1    Beil, M.2    Magin, T.M.3    Leube, R.E.4
  • 42
    • 33745873555 scopus 로고    scopus 로고
    • "heads and tails" of intermediate filament phosphorylation: Multiple sites and functional insights
    • Omary MB, Ku NO, Tao GZ, Toivola DM, Liao J. "Heads and tails" of intermediate filament phosphorylation: multiple sites and functional insights. Trends Biochem Sci 2006; 31: 383-94.
    • (2006) Trends Biochem Sci , vol.31 , pp. 383-394
    • Omary, M.B.1    Ku, N.O.2    Tao, G.Z.3    Toivola, D.M.4    Liao, J.5
  • 43
    • 70449728458 scopus 로고    scopus 로고
    • Keratins regulate protein biosynthesis through localization of GLUT1 and-3 upstream of AMP kinase and Raptor
    • Vijayaraj P, Kroger C, Reuter U, Windoffer R, Leube RE, Magin TM. Keratins regulate protein biosynthesis through localization of GLUT1 and-3 upstream of AMP kinase and Raptor. J Cell Biol 2009; 187: 175-84.
    • (2009) J Cell Biol , vol.187 , pp. 175-184
    • Vijayaraj, P.1    Kroger, C.2    Reuter, U.3    Windoffer, R.4    Leube, R.E.5    Magin, T.M.6
  • 45
    • 72449187655 scopus 로고    scopus 로고
    • The intersections between O-GlcNAcylation and phosphorylation: Implications for multiple signaling pathways
    • Zeidan Q, Hart GW. The intersections between O-GlcNAcylation and phosphorylation: implications for multiple signaling pathways. J Cell Sci 2010; 123(Pt 1): 13-22.
    • (2010) J Cell Sci , vol.123 , pp. 13-22
    • Zeidan, Q.1    Hart, G.W.2
  • 46
    • 77956412905 scopus 로고    scopus 로고
    • Cytoskeletal keratin glycosylation protects epithelial tissue from injury
    • Ku NO, Toivola DM, Strnad P, Omary MB. Cytoskeletal keratin glycosylation protects epithelial tissue from injury. Nat Cell Biol 2010; 12: 876-85.
    • (2010) Nat Cell Biol , vol.12 , pp. 876-885
    • Ku, N.O.1    Toivola, D.M.2    Strnad, P.3    Omary, M.B.4
  • 47
    • 0034791125 scopus 로고    scopus 로고
    • Inhibition of protein kinase B (PKB) and PKCzeta mediates keratin K10-induced cell cycle arrest
    • Paramio JM, Segrelles C, Ruiz S, Jorcano JL. Inhibition of protein kinase B (PKB) and PKCzeta mediates keratin K10-induced cell cycle arrest. Mol Cell Biol 2001; 21: 7449-59.
    • (2001) Mol Cell Biol , vol.21 , pp. 7449-7459
    • Paramio, J.M.1    Segrelles, C.2    Ruiz, S.3    Jorcano, J.L.4
  • 48
    • 77958616531 scopus 로고    scopus 로고
    • O-GlcNAcylation determines the solubility, filament organization, and stability of keratins 8 and 18
    • Srikanth B, Vaidya MM, Kalraiya RD. O-GlcNAcylation determines the solubility, filament organization, and stability of keratins 8 and 18. J Biol Chem 2010; 285: 34062-71.
    • (2010) J Biol Chem , vol.285 , pp. 34062-34071
    • Srikanth, B.1    Vaidya, M.M.2    Kalraiya, R.D.3
  • 49
    • 0034523266 scopus 로고    scopus 로고
    • SUMO-nonclassical ubiquitin
    • Melchior F. SUMO-nonclassical ubiquitin. Annu Rev Cell Dev Biol 2000; 16: 591-626.
    • (2000) Annu Rev Cell Dev Biol , vol.16 , pp. 591-626
    • Melchior, F.1
  • 50
    • 47549109045 scopus 로고    scopus 로고
    • Sumoylation regulates lamin A function and is lost in lamin A mutants associated with familial cardio-myopathies
    • Zhang YQ, Sarge KD. Sumoylation regulates lamin A function and is lost in lamin A mutants associated with familial cardio-myopathies. J Cell Biol 2008; 182: 35-9.
    • (2008) J Cell Biol , vol.182 , pp. 35-39
    • Zhang, Y.Q.1    Sarge, K.D.2
  • 53
    • 71549169907 scopus 로고    scopus 로고
    • SUMO regulates the assembly and function of a cytoplasmic intermediate filament protein in C. Elegans
    • Kaminsky R, Denison C, Bening-Abu-Shach U, Chisholm AD, Gygi SP, Broday L. SUMO regulates the assembly and function of a cytoplasmic intermediate filament protein in C. elegans. Dev Cell 2009; 17: 724-35.
    • (2009) Dev Cell , vol.17 , pp. 724-735
    • Kaminsky, R.1    Denison, C.2    Bening-Abu-Shach, U.3    Chisholm, A.D.4    Gygi, S.P.5    Broday, L.6
  • 54
    • 79952264626 scopus 로고    scopus 로고
    • A tension-induced mechanotransduction pathway promotes epithelial morphogenesis
    • Zhang H, Landmann F, Zahreddine H, Rodriguez D, Koch M, Labouesse M. A tension-induced mechanotransduction pathway promotes epithelial morphogenesis. Nature 2011; 471: 99-103.
    • (2011) Nature , vol.471 , pp. 99-103
    • Zhang, H.1    Landmann, F.2    Zahreddine, H.3    Rodriguez, D.4    Koch, M.5    Labouesse, M.6
  • 55
    • 68849091625 scopus 로고    scopus 로고
    • Epidermolysis bullosa simplex: A paradigm for disorders of tissue fragility
    • Coulombe PA, Kerns ML, Fuchs E. Epidermolysis bullosa simplex: a paradigm for disorders of tissue fragility. J Clin Invest 2009; 119: 1784-93.
    • (2009) J Clin Invest , vol.119 , pp. 1784-1793
    • Coulombe, P.A.1    Kerns, M.L.2    Fuchs, E.3
  • 56
    • 0036443637 scopus 로고    scopus 로고
    • Characterization of early assembly intermediates of recombinant human keratins
    • Herrmann H, Wedig T, Porter RM, Lane EB, Aebi U. Characterization of early assembly intermediates of recombinant human keratins. J Struct Biol 2002; 137: 82-96.
    • (2002) J Struct Biol , vol.137 , pp. 82-96
    • Herrmann, H.1    Wedig, T.2    Porter, R.M.3    Lane, E.B.4    Aebi, U.5
  • 58
    • 80052825482 scopus 로고    scopus 로고
    • A new case of keratin 14 functional knockout causes severe recessive EBS and questions the haploinsufficiency model of Naegeli-Franceschetti-Jadassohn syndrome
    • Titeux M, Decha A, Pironon N, Tonasso L, Gasc G, Mejia JE, Prost-Squarcioni C, Hovnanian A. A new case of keratin 14 functional knockout causes severe recessive EBS and questions the haploinsufficiency model of Naegeli-Franceschetti-Jadassohn syndrome. J Invest Dermatol 2011; 10: 2131-3.
    • (2011) J Invest Dermatol , vol.10 , pp. 2131-2133
    • Titeux, M.1    Decha, A.2    Pironon, N.3    Tonasso, L.4    Gasc, G.5    Mejia, J.E.6    Prost-Squarcioni, C.7    Hovnanian, A.8
  • 59
    • 0026522850 scopus 로고
    • Interference in vimentin assembly in vitro by synthetic peptides derived from the vimentin head domain
    • Hofmann I, Herrmann H. Interference in vimentin assembly in vitro by synthetic peptides derived from the vimentin head domain. J Cell Sci 1992; 101(Pt 3): 687-700.
    • (1992) J Cell Sci , vol.101 , pp. 687-700
    • Hofmann, I.1    Herrmann, H.2
  • 60
    • 36248998854 scopus 로고    scopus 로고
    • Induction of inflammatory cytokines by a keratin mutation and their repression by a small molecule in a mouse model for EBS
    • Lu H, Chen J, Planko L, Zigrino P, Klein-Hitpass L, Magin TM. Induction of inflammatory cytokines by a keratin mutation and their repression by a small molecule in a mouse model for EBS. J Invest Dermatol 2007; 127: 2781-9.
    • (2007) J Invest Dermatol , vol.127 , pp. 2781-2789
    • Lu, H.1    Chen, J.2    Planko, L.3    Zigrino, P.4    Klein-Hitpass, L.5    Magin, T.M.6
  • 63
    • 77952717243 scopus 로고    scopus 로고
    • Identification of novel and known KRT5 and KRT14 mutations in 53 patients with epidermolysis bullosa simplex: Correlation between genotype and phenotype
    • Arin MJ, Grimberg G, Schumann H, De AH Jr., Chang YR, Tadini G, Kohlhase J, Krieg T, Bruckner-Tuderman L, Has C. Identification of novel and known KRT5 and KRT14 mutations in 53 patients with epidermolysis bullosa simplex: correlation between genotype and phenotype. Br J Dermatol 2010; 162: 1365-9.
    • (2010) Br J Dermatol , vol.162 , pp. 1365-1369
    • Arin, M.J.1    Grimberg, G.2    Schumann, H.3    De, A.H.4    Chang, Y.R.5    Tadini, G.6    Kohlhase, J.7    Krieg, T.8    Bruckner-Tuderman, L.9    Has, C.10
  • 64
    • 18244368252 scopus 로고    scopus 로고
    • Mutation analysis of human cytokeratin 8 gene in malignant rhabdoid tumor: A possible association with intracytoplasmic inclusion body formation
    • Shiratsuchi H, Saito T, Sakamoto A, Itakura E, Tamiya S, Oshiro Y, Oda Y, Toh S, Komiyama S, Tsuneyoshi M. Mutation analysis of human cytokeratin 8 gene in malignant rhabdoid tumor: a possible association with intracytoplasmic inclusion body formation. Mod Pathol 2002; 15: 146-53.
    • (2002) Mod Pathol , vol.15 , pp. 146-153
    • Shiratsuchi, H.1    Saito, T.2    Sakamoto, A.3    Itakura, E.4    Tamiya, S.5    Oshiro, Y.6    Oda, Y.7    Toh, S.8    Komiyama, S.9    Tsuneyoshi, M.10
  • 66
    • 77953916528 scopus 로고    scopus 로고
    • HSP90 at the hub of protein homeostasis: Emerging mechanistic insights
    • Taipale M, Jarosz DF, Lindquist S. HSP90 at the hub of protein homeostasis: emerging mechanistic insights. Nat Rev Mol Cell Biol 2010; 11: 515-28.
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 515-528
    • Taipale, M.1    Jarosz, D.F.2    Lindquist, S.3
  • 67
    • 52649111039 scopus 로고    scopus 로고
    • Basal cell carcinomas: Attack of the hedgehog
    • Epstein EH. Basal cell carcinomas: attack of the hedgehog. Nat Rev Cancer 2008; 8: 743-54.
    • (2008) Nat Rev Cancer , vol.8 , pp. 743-754
    • Epstein, E.H.1
  • 69
    • 33646552082 scopus 로고    scopus 로고
    • Keratin 17 modulates hair follicle cycling in a TNFalpha-dependent fashion
    • Tong X, Coulombe PA. Keratin 17 modulates hair follicle cycling in a TNFalpha-dependent fashion. Genes Dev 2006; 20: 1353-64.
    • (2006) Genes Dev , vol.20 , pp. 1353-1364
    • Tong, X.1    Coulombe, P.A.2
  • 70
    • 77957584091 scopus 로고    scopus 로고
    • Keratin 17 promotes epithelial proliferation and tumor growth by polarizing the immune response in skin
    • Depianto D, Kerns ML, Dlugosz AA, Coulombe PA. Keratin 17 promotes epithelial proliferation and tumor growth by polarizing the immune response in skin. Nat Genet 2010; 42: 910-4.
    • (2010) Nat Genet , vol.42 , pp. 910-914
    • Depianto, D.1    Kerns, M.L.2    Dlugosz, A.A.3    Coulombe, P.A.4
  • 71
    • 23344454128 scopus 로고    scopus 로고
    • Exploiting the keratin 17 gene promoter to visualize live cells in epithelial appendages of mice
    • Bianchi N, Depianto D, McGowan K, Gu C, Coulombe PA. Exploiting the keratin 17 gene promoter to visualize live cells in epithelial appendages of mice. Mol Cell Biol 2005; 25: 7249-59.
    • (2005) Mol Cell Biol , vol.25 , pp. 7249-7259
    • Bianchi, N.1    Depianto, D.2    McGowan, K.3    Gu, C.4    Coulombe, P.A.5
  • 72
    • 33846966636 scopus 로고    scopus 로고
    • A brief history of T(H) 17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage
    • Steinman L. A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage. Nat Med 2007; 13: 139-45.
    • (2007) Nat Med , vol.13 , pp. 139-145
    • Steinman, L.1
  • 74
    • 34547892659 scopus 로고    scopus 로고
    • Differentiation between pancreaticobiliary and upper gastrointestinal adenocarcinomas: Is analysis of cytokeratin 17 expression helpful?
    • Sarbia M, Fritze F, Geddert H, von WC, Rosenberg R, Gellert K. Differentiation between pancreaticobiliary and upper gastrointestinal adenocarcinomas: is analysis of cytokeratin 17 expression helpful? Am J Clin Pathol 2007; 128: 255-9.
    • (2007) Am J Clin Pathol , vol.128 , pp. 255-259
    • Sarbia, M.1    Fritze, F.2    Geddert, H.3    Von Wc Rosenberg, R.4    Gellert, K.5
  • 75
    • 79551487388 scopus 로고    scopus 로고
    • Expanding the keratin mutation database: Novel and recurrent mutations and genotype-phenotype correlations in 28 patients with epidermolytic ichthyosis
    • Arin MJ, Oji V, Emmert S, Hausser I, Traupe H, Krieg T, Grimberg G. Expanding the keratin mutation database: novel and recurrent mutations and genotype-phenotype correlations in 28 patients with epidermolytic ichthyosis. Br J Dermatol 2011; 164: 442-7.
    • (2011) Br J Dermatol , vol.164 , pp. 442-447
    • Arin, M.J.1    Oji, V.2    Emmert, S.3    Hausser, I.4    Traupe, H.5    Krieg, T.6    Grimberg, G.7
  • 77
    • 79960296401 scopus 로고    scopus 로고
    • Chemical chaperones protect epidermolysis bullosa simplex keratinocytes from heat stress-induced keratin aggregation: Involvement of heat shock proteins and MAP kinases
    • Chamcheu JC, Navsaria H, Pihl-Lundin I, Liovic M, Vahlquist A, Torma H. Chemical chaperones protect epidermolysis bullosa simplex keratinocytes from heat stress-induced keratin aggregation: involvement of heat shock proteins and MAP kinases. J Invest Dermatol 2011; 131: 1684-91.
    • (2011) J Invest Dermatol , vol.131 , pp. 1684-1691
    • Chamcheu, J.C.1    Navsaria, H.2    Pihl-Lundin, I.3    Liovic, M.4    Vahlquist, A.5    Torma, H.6
  • 78
    • 0029063952 scopus 로고
    • Identification and mutational analysis of the glycosylation sites of human keratin 18
    • Ku N-O, Omary MB. Identification and mutational analysis of the glycosylation sites of human keratin 18. J Biol Chem 1995; 270: 11820-7.
    • (1995) J Biol Chem , vol.270 , pp. 11820-11827
    • Ku, N.-O.1    Omary, M.B.2
  • 79
    • 0024384842 scopus 로고
    • Cytokeratin 13 contains O-glycosidically linked N-acetylglucosamine residues
    • King IA, Hounsell EF. Cytokeratin 13 contains O-glycosidically linked N-acetylglucosamine residues. J Biol Chem 1989; 264: 14022-8.
    • (1989) J Biol Chem , vol.264 , pp. 14022-14028
    • King, I.A.1    Hounsell, E.F.2
  • 80
    • 0027506091 scopus 로고
    • Mitotic arrest-associated enhancement of O-linked glycosylation and phosphorylation of human keratins 8 and 18
    • Chou CF, Omary MB. Mitotic arrest-associated enhancement of O-linked glycosylation and phosphorylation of human keratins 8 and 18. J Biol Chem 1995; 268: 4465-72.
    • (1995) J Biol Chem , vol.268 , pp. 4465-4472
    • Chou, C.F.1    Omary, M.B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.