The ubiquitin ligase CHIP/STUB1 targets mutant keratins for degradation

Human Mutation

Volumn 31, Issue 4, 2010, Pages 466-476

  Löffek, Stefanie ^a   Wöll, Stefan ^b   Höhfeld, Jörg ^a   Leube, Rudolf E ^b   Has, Cristina ^c   Bruckner Tuderman, Leena ^c,d   Magin, Thomas M ^a  

^a UNIVERSITY OF BONN   (Germany)

^b RWTH AACHEN UNIVERSITY   (Germany)

^c UNIVERSITY OF FREIBURG   (Germany)

^d UNIVERSITY OF FREIBURG   (Germany)

Author keywords

CHIP; EBS; Epidermolysis bullosa simplex; Hsc70; Hsp70; KRT14; KRT5

Indexed keywords

CARBOXYL TERMINUS OF HSC/P70 INTERACTING PROTEIN; CHAPERONE; CYTOKERATIN 14; HEAT SHOCK COGNATE PROTEIN 70; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; EPIDERMOLYSIS BULLOSA SIMPLEX; GENE MUTATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MOUSE; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ANIMALS; CELL LINE, TUMOR; EPIDERMOLYSIS BULLOSA SIMPLEX; HSC70 HEAT-SHOCK PROTEINS; HUMANS; KERATINS; MICE; MODELS, BIOLOGICAL; MOLECULAR CHAPERONES; MUTANT PROTEINS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, QUATERNARY; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

MUS;

EID: 77950415624     PISSN: 10597794     EISSN: 10981004     Source Type: Journal    
DOI: 10.1002/humu.21222     Document Type: Article

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