-
1
-
-
77958125017
-
Discovery of the Negative Regulator of Nrf2, Keap1: a historical overview
-
Itoh K., Mimura J., Yamamoto M. Discovery of the Negative Regulator of Nrf2, Keap1: a historical overview. Antioxid. Redox Signal. 2010, 13:1665-1678.
-
(2010)
Antioxid. Redox Signal.
, vol.13
, pp. 1665-1678
-
-
Itoh, K.1
Mimura, J.2
Yamamoto, M.3
-
2
-
-
77958114117
-
Regulation of Nrf2 signaling for cancer chemoprevention: antioxidant coupled with anti-inflammatory
-
Hu R., Saw C.L., Yu R., Kong A.N. Regulation of Nrf2 signaling for cancer chemoprevention: antioxidant coupled with anti-inflammatory. Antioxid. Redox Signal. 2010, 13:1679-1698.
-
(2010)
Antioxid. Redox Signal.
, vol.13
, pp. 1679-1698
-
-
Hu, R.1
Saw, C.L.2
Yu, R.3
Kong, A.N.4
-
3
-
-
77958115724
-
Regulation of the Nrf2-Keap1 antioxidant response by the ubiquitin proteasome system: an insight into cullin-ring ubiquitin ligases
-
Villeneuve N.F., Lau A., Zhang D.D. Regulation of the Nrf2-Keap1 antioxidant response by the ubiquitin proteasome system: an insight into cullin-ring ubiquitin ligases. Antioxid. Redox Signal. 2010, 13:1699-1712.
-
(2010)
Antioxid. Redox Signal.
, vol.13
, pp. 1699-1712
-
-
Villeneuve, N.F.1
Lau, A.2
Zhang, D.D.3
-
4
-
-
77958130983
-
Cancer chemoprevention mechanisms mediated through the Keap1-Nrf2 pathway
-
Hayes J.D., McMahon M., Chowdhry S., et al. Cancer chemoprevention mechanisms mediated through the Keap1-Nrf2 pathway. Antioxid. Redox Signal. 2010, 13:1713-1748.
-
(2010)
Antioxid. Redox Signal.
, vol.13
, pp. 1713-1748
-
-
Hayes, J.D.1
McMahon, M.2
Chowdhry, S.3
-
5
-
-
77958140054
-
The Nrf2-Keap1-ARE signaling pathway: the regulation and dual. function of Nrf2 in cancer
-
Zhang D.D. The Nrf2-Keap1-ARE signaling pathway: the regulation and dual. function of Nrf2 in cancer. Antioxid. Redox Signal. 2010, 13:1623-1626.
-
(2010)
Antioxid. Redox Signal.
, vol.13
, pp. 1623-1626
-
-
Zhang, D.D.1
-
6
-
-
77957796093
-
Nrf2-deficiency creates a responsive microenvironment for metastasis to the lung
-
Satoh H., Moriguchi T., Taguchi K., et al. Nrf2-deficiency creates a responsive microenvironment for metastasis to the lung. Carcinogenesis 2010, 31:1833-1843.
-
(2010)
Carcinogenesis
, vol.31
, pp. 1833-1843
-
-
Satoh, H.1
Moriguchi, T.2
Taguchi, K.3
-
7
-
-
17644390613
-
Controlled elimination of intracellular H(2)O(2): regulation of peroxiredoxin, catalase, and glutathione peroxidase via post-translational modification
-
Rhee S.G., Yang KS, Kang S.W., Woo H.A., et al. Controlled elimination of intracellular H(2)O(2): regulation of peroxiredoxin, catalase, and glutathione peroxidase via post-translational modification. Antioxid. Redox Signal. 2005, 7:619-626.
-
(2005)
Antioxid. Redox Signal.
, vol.7
, pp. 619-626
-
-
Rhee, S.G.1
Yang, K.S.2
Kang, S.W.3
Woo, H.A.4
-
8
-
-
13544272571
-
Reduction of cysteine sulfinic acid by sulfiredoxin is specific to 2-cys peroxiredoxins
-
Woo H.A., Jeong W., Chang T.S., et al. Reduction of cysteine sulfinic acid by sulfiredoxin is specific to 2-cys peroxiredoxins. J. Biol. Chem. 2005, 280:3125-3128.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 3125-3128
-
-
Woo, H.A.1
Jeong, W.2
Chang, T.S.3
-
10
-
-
50049129246
-
Protein cysteine sulfinic acid reductase (sulfiredoxin) as a regulator of cell proliferation and drug response
-
Lei K., Townsend D.M., Tew K.D. Protein cysteine sulfinic acid reductase (sulfiredoxin) as a regulator of cell proliferation and drug response. Oncogene 2008, 27:4877-4887.
-
(2008)
Oncogene
, vol.27
, pp. 4877-4887
-
-
Lei, K.1
Townsend, D.M.2
Tew, K.D.3
-
11
-
-
70349311825
-
Transcriptional regulation of the AP-1 and Nrf2 target gene sulfiredoxin
-
Soriano F.X., Baxter P., Murray L.M., et al. Transcriptional regulation of the AP-1 and Nrf2 target gene sulfiredoxin. Mol. Cells 2009, 27:279-282.
-
(2009)
Mol. Cells
, vol.27
, pp. 279-282
-
-
Soriano, F.X.1
Baxter, P.2
Murray, L.M.3
-
12
-
-
58149099624
-
Nrf2-dependent sulfiredoxin-1 expression protects against cigarette smoke-induced oxidative stress in lungs
-
Singh A., Ling G., Suhasini A.N., et al. Nrf2-dependent sulfiredoxin-1 expression protects against cigarette smoke-induced oxidative stress in lungs. Free Radic. Biol. Med. 2009, 46:376-386.
-
(2009)
Free Radic. Biol. Med.
, vol.46
, pp. 376-386
-
-
Singh, A.1
Ling, G.2
Suhasini, A.N.3
-
13
-
-
58149393166
-
Sulfiredoxin is an AP-1 target gene that is required for transformation and shows elevated expression in human skin malignancies
-
Wei Q., Jiang H., Matthews C.P., et al. Sulfiredoxin is an AP-1 target gene that is required for transformation and shows elevated expression in human skin malignancies. Proc. Natl. Acad. Sci. USA 2008, 105:19738-19743.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 19738-19743
-
-
Wei, Q.1
Jiang, H.2
Matthews, C.P.3
-
14
-
-
0345357664
-
Down regulation of DJ-1 enhances cell death by oxidative stress, ER stress, and proteasome inhibition
-
Yokota T., Sugawara K., Ito K., et al. Down regulation of DJ-1 enhances cell death by oxidative stress, ER stress, and proteasome inhibition. Biochem. Biophys. Res. Commun. 2003, 312:1342-1348.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.312
, pp. 1342-1348
-
-
Yokota, T.1
Sugawara, K.2
Ito, K.3
-
15
-
-
62749199149
-
DJ-1 immunoreactivity in human brain astrocytes is dependent on infarct presence and infarct age
-
Mullett S.J., Hamilton R.L., Hinkle D.A. DJ-1 immunoreactivity in human brain astrocytes is dependent on infarct presence and infarct age. Neuropathology 2009, 29:125-131.
-
(2009)
Neuropathology
, vol.29
, pp. 125-131
-
-
Mullett, S.J.1
Hamilton, R.L.2
Hinkle, D.A.3
-
16
-
-
67650095406
-
The PTEN regulator DJ-1 is associated with hTERT expression in clear cell renal cell carcinoma
-
Sitaram R.T., Cairney C.J., Grabowski P., et al. The PTEN regulator DJ-1 is associated with hTERT expression in clear cell renal cell carcinoma. Int. J. Cancer 2009, 125:783-790.
-
(2009)
Int. J. Cancer
, vol.125
, pp. 783-790
-
-
Sitaram, R.T.1
Cairney, C.J.2
Grabowski, P.3
-
17
-
-
51049093372
-
Expression and role of DJ-1 in leukemia
-
Liu H., Wang M., Li M., Wang J., et al. Expression and role of DJ-1 in leukemia. Biochem. Biophys. Res. Commun. 2008, 375:477-483.
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.375
, pp. 477-483
-
-
Liu, H.1
Wang, M.2
Li, M.3
Wang, J.4
-
18
-
-
77649242821
-
Prognostic significance of nuclear DJ-1 expression in astrocytoma
-
Miyajima Y., Sato Y., Oka H., et al. Prognostic significance of nuclear DJ-1 expression in astrocytoma. Anticancer Res. 2010, 30:265-269.
-
(2010)
Anticancer Res.
, vol.30
, pp. 265-269
-
-
Miyajima, Y.1
Sato, Y.2
Oka, H.3
-
19
-
-
67349264491
-
Involvement of ERK1/2 signaling pathway in DJ-1-induced neuroprotection against oxidative stress
-
Gu L., Cui T., Fan C., et al. Involvement of ERK1/2 signaling pathway in DJ-1-induced neuroprotection against oxidative stress. Biochem. Biophys. Res. Commun. 2009, 383:469-474.
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.383
, pp. 469-474
-
-
Gu, L.1
Cui, T.2
Fan, C.3
-
20
-
-
59049105937
-
DJ-1/PARK7 is an important mediator of hypoxia-induced cellular responses
-
Vasseur S., Afzal S., Tardivel-Lacombe J., et al. DJ-1/PARK7 is an important mediator of hypoxia-induced cellular responses. Proc. Natl. Acad. Sci. USA 2009, 106:1111-1116.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 1111-1116
-
-
Vasseur, S.1
Afzal, S.2
Tardivel-Lacombe, J.3
-
21
-
-
40849138195
-
DJ-1 decreases Bax expression through repressing p53 transcriptional activity
-
Fan J., Ren H., Jia N., et al. DJ-1 decreases Bax expression through repressing p53 transcriptional activity. J. Biol. Chem. 2008, 283:4022-4030.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 4022-4030
-
-
Fan, J.1
Ren, H.2
Jia, N.3
-
22
-
-
77949623516
-
Reduced basal autophagy and impaired mitochondrial dynamics due to loss of Parkinson's disease-associated protein DJ-1
-
Krebiehl G., Ruckerbauer S., Burbulla L.F., et al. Reduced basal autophagy and impaired mitochondrial dynamics due to loss of Parkinson's disease-associated protein DJ-1. PLoS One 2010, 5:e9367.
-
(2010)
PLoS One
, vol.5
-
-
Krebiehl, G.1
Ruckerbauer, S.2
Burbulla, L.F.3
-
23
-
-
33750052885
-
DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2
-
Clements C.M., McNally R.S., Conti B.J., et al. DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2. Proc. Natl. Acad. Sci. USA 2006, 103:15091-15096.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 15091-15096
-
-
Clements, C.M.1
McNally, R.S.2
Conti, B.J.3
-
25
-
-
77955960441
-
Cell-specific elevation of NRF2 and sulfiredoxin-1 as markers of oxidative stress in the lungs of idiopathic pulmonary fibrosis and non-specific interstitial pneumonia
-
Mazur W., Lindholm P., Vuorinen K., Myllärniemi M., Salmenkivi K., Kinnula V.L. Cell-specific elevation of NRF2 and sulfiredoxin-1 as markers of oxidative stress in the lungs of idiopathic pulmonary fibrosis and non-specific interstitial pneumonia. APMIS 2010, 118:703-712.
-
(2010)
APMIS
, vol.118
, pp. 703-712
-
-
Mazur, W.1
Lindholm, P.2
Vuorinen, K.3
Myllärniemi, M.4
Salmenkivi, K.5
Kinnula, V.L.6
-
26
-
-
54249087596
-
RNAi-mediated silencing of nuclear factor erythroid-2-related factor 2 gene expression in non-small cell lung cancer inhibits tumor growth and increases efficacy of chemotherapy
-
Singh A., Boldin-Adamsky S., Thimmulappa R.K., et al. RNAi-mediated silencing of nuclear factor erythroid-2-related factor 2 gene expression in non-small cell lung cancer inhibits tumor growth and increases efficacy of chemotherapy. Cancer Res. 2008, 68:7975-7984.
-
(2008)
Cancer Res.
, vol.68
, pp. 7975-7984
-
-
Singh, A.1
Boldin-Adamsky, S.2
Thimmulappa, R.K.3
-
27
-
-
77954695549
-
Nrf2 and Keap1 abnormalities in non-small cell lung carcinoma and association with clinicopathologic features
-
Solis L.M., Behrens C., Dong W., et al. Nrf2 and Keap1 abnormalities in non-small cell lung carcinoma and association with clinicopathologic features. Clin. Cancer Res. 2010, 16:3743-3753.
-
(2010)
Clin. Cancer Res.
, vol.16
, pp. 3743-3753
-
-
Solis, L.M.1
Behrens, C.2
Dong, W.3
-
28
-
-
15244356847
-
Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice
-
Rangasamy T., Cho C.Y., Thimmulappa R.K., et al. Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice. J. Clin. Invest. 2004, 114:1248-1259.
-
(2004)
J. Clin. Invest.
, vol.114
, pp. 1248-1259
-
-
Rangasamy, T.1
Cho, C.Y.2
Thimmulappa, R.K.3
-
29
-
-
78049370987
-
Oxidative stress, inflammation, and cancer: how are they linked?
-
Reuter S., GuptaSC, Chaturvedi M.M., et al. Oxidative stress, inflammation, and cancer: how are they linked?. Free Radic. Biol. Med. 2010, 49:1603-1616.
-
(2010)
Free Radic. Biol. Med.
, vol.49
, pp. 1603-1616
-
-
Reuter, S.1
Gupta, S.C.2
Chaturvedi, M.M.3
-
30
-
-
33748255958
-
Increased expression of nuclear factor E2 p45-related factor 2 (NRF2) in head and neck squamous cell carcinomas
-
Stacy D.R., Ely K., Massion P.P., et al. Increased expression of nuclear factor E2 p45-related factor 2 (NRF2) in head and neck squamous cell carcinomas. Head Neck 2006, 28:813-818.
-
(2006)
Head Neck
, vol.28
, pp. 813-818
-
-
Stacy, D.R.1
Ely, K.2
Massion, P.P.3
-
31
-
-
77953223169
-
DJ-1: a novel independent prognostic marker for survival in glottic squamous cell carcinoma
-
Zhu X.L., Wang Z.F., Lei W.B., et al. DJ-1: a novel independent prognostic marker for survival in glottic squamous cell carcinoma. Cancer Sci. 2010, 101:1320-1325.
-
(2010)
Cancer Sci.
, vol.101
, pp. 1320-1325
-
-
Zhu, X.L.1
Wang, Z.F.2
Lei, W.B.3
-
32
-
-
84858158377
-
Nuclear factor erythroid-derived 2-like 2 (Nrf2) and DJ1 are prognostic factors in lung cancer
-
Merikallio H., Pääkkö P., Kinnula V.L., et al. Nuclear factor erythroid-derived 2-like 2 (Nrf2) and DJ1 are prognostic factors in lung cancer. Hum. Pathol. 2012, 43:577-584.
-
(2012)
Hum. Pathol.
, vol.43
, pp. 577-584
-
-
Merikallio, H.1
Pääkkö, P.2
Kinnula, V.L.3
-
33
-
-
79952691516
-
Serum DJ-1 as a diagnostic marker and prognostic factor for pancreatic cancer
-
He X.Y., Liu B.Y., Yao W.Y., et al. Serum DJ-1 as a diagnostic marker and prognostic factor for pancreatic cancer. J. Dig. Dis. 2011, 12:131-137.
-
(2011)
J. Dig. Dis.
, vol.12
, pp. 131-137
-
-
He, X.Y.1
Liu, B.Y.2
Yao, W.Y.3
-
34
-
-
84866733906
-
DJ-1, a novel biomarker and a selected target gene for overcoming chemoresistance in pancreatic cancer
-
Chen Y., Kang M., Lu W., et al. DJ-1, a novel biomarker and a selected target gene for overcoming chemoresistance in pancreatic cancer. J. Cancer Res. Clin. Oncol. 2010, 138:1463-1474.
-
(2010)
J. Cancer Res. Clin. Oncol.
, vol.138
, pp. 1463-1474
-
-
Chen, Y.1
Kang, M.2
Lu, W.3
-
35
-
-
51349092847
-
Proteomic analysis identifies MMP-9, DJ-1 and A1BG as over expressed proteins in pancreatic juice from pancreatic ductal adenocarcinoma patients
-
Tian M., Cui Y.Z., Song G.H., et al. Proteomic analysis identifies MMP-9, DJ-1 and A1BG as over expressed proteins in pancreatic juice from pancreatic ductal adenocarcinoma patients. BMC Cancer 2008, 8:241.
-
(2008)
BMC Cancer
, vol.8
, pp. 241
-
-
Tian, M.1
Cui, Y.Z.2
Song, G.H.3
|