-
2
-
-
33645728523
-
Neurodegenerative diseases: New concepts of pathogenesis and their therapeutic implications
-
Skovronsky, D. M., Lee, V. M., and Trojanowski, J. Q. (2006) Neurodegenerative diseases: new concepts of pathogenesis and their therapeutic implications. Annu. Rev. Pathol. 1, 151-170
-
(2006)
Annu. Rev. Pathol.
, vol.1
, pp. 151-170
-
-
Skovronsky, D.M.1
Lee, V.M.2
Trojanowski, J.Q.3
-
3
-
-
33847662852
-
Soluble protein oligomers in neurodegeneration: Lessons from the Alzheimer's amyloid β-peptide
-
Haass, C., and Selkoe, D. J. (2007) Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid β-peptide. Nat. Rev. Mol. Cell Biol. 8, 101-112
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 101-112
-
-
Haass, C.1
Selkoe, D.J.2
-
4
-
-
77956698237
-
Preparation and characterization of toxic Aβ aggregates for structural and functional studies in Alzheimer's disease research
-
Jan, A., Hartley, D. M., and Lashuel, H. A. (2010) Preparation and characterization of toxic Aβ aggregates for structural and functional studies in Alzheimer's disease research. Nat. Protoc. 5, 1186-1209
-
(2010)
Nat. Protoc.
, vol.5
, pp. 1186-1209
-
-
Jan, A.1
Hartley, D.M.2
Lashuel, H.A.3
-
5
-
-
0033570337
-
Protofibrillar intermediates of amyloid β-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons
-
Hartley, D. M., Walsh, D. M., Ye, C. P., Diehl, T., Vasquez, S., Vassilev, P. M., Teplow, D. B., and Selkoe, D. J. (1999) Protofibrillar intermediates of amyloid β-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons. J. Neurosci. 19, 8876-8884
-
(1999)
J. Neurosci.
, vol.19
, pp. 8876-8884
-
-
Hartley, D.M.1
Walsh, D.M.2
Ye, C.P.3
Diehl, T.4
Vasquez, S.5
Vassilev, P.M.6
Teplow, D.B.7
Selkoe, D.J.8
-
6
-
-
0041825430
-
Mixtures of wild-type and a pathogenic (E22G) form of Aβ40 in vitro accumulate protofibrils, including amyloid pores
-
Lashuel, H. A., Hartley, D. M., Petre, B. M., Wall, J. S., Simon, M. N., Walz, T., and Lansbury, P. T., Jr. (2003) Mixtures of wild-type and a pathogenic (E22G) form of Aβ40 in vitro accumulate protofibrils, including amyloid pores. J. Mol. Biol. 332, 795-808
-
(2003)
J. Mol. Biol.
, vol.332
, pp. 795-808
-
-
Lashuel, H.A.1
Hartley, D.M.2
Petre, B.M.3
Wall, J.S.4
Simon, M.N.5
Walz, T.6
Lansbury Jr., P.T.7
-
7
-
-
0033520461
-
Amyloid β-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates
-
Walsh, D. M., Hartley, D. M., Kusumoto, Y., Fezoui, Y., Condron, M. M., Lomakin, A., Benedek, G. B., Selkoe, D. J., and Teplow, D. B. (1999) Amyloid β-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates. J. Biol. Chem. 274, 25945-25952
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 25945-25952
-
-
Walsh, D.M.1
Hartley, D.M.2
Kusumoto, Y.3
Fezoui, Y.4
Condron, M.M.5
Lomakin, A.6
Benedek, G.B.7
Selkoe, D.J.8
Teplow, D.B.9
-
8
-
-
0030799122
-
Amyloid β-protein fibrillogenesis. Detection of a protofibrillar intermediate
-
Walsh, D. M., Lomakin, A., Benedek, G. B., Condron, M. M., and Teplow, D. B. (1997) Amyloid β-protein fibrillogenesis. Detection of a protofibrillar intermediate. J. Biol. Chem. 272, 22364-22372
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 22364-22372
-
-
Walsh, D.M.1
Lomakin, A.2
Benedek, G.B.3
Condron, M.M.4
Teplow, D.B.5
-
9
-
-
79958249995
-
Interaction between prion protein and toxic amyloid β assemblies can be therapeutically targeted at multiple sites
-
Freir, D. B., Nicoll, A. J., Klyubin, I., Panico, S., Mc Donald, J. M., Risse, E., Asante, E. A., Farrow, M. A., Sessions, R. B., Saibil, H. R., Clarke, A. R., Rowan, M. J., Walsh, D. M., and Collinge, J. (2011) Interaction between prion protein and toxic amyloid β assemblies can be therapeutically targeted at multiple sites. Nat. Commun. 2, 336
-
(2011)
Nat. Commun.
, vol.2
, pp. 336
-
-
Freir, D.B.1
Nicoll, A.J.2
Klyubin, I.3
Panico, S.4
Mc Donald, J.M.5
Risse, E.6
Asante, E.A.7
Farrow, M.A.8
Sessions, R.B.9
Saibil, H.R.10
Clarke, A.R.11
Rowan, M.J.12
Walsh, D.M.13
Collinge, J.14
-
10
-
-
33845935564
-
Solution state characterization of amyloid β-derived diffusible ligands
-
Hepler, R. W., Grimm, K. M., Nahas, D. D., Breese, R., Dodson, E. C., Acton, P., Keller, P. M., Yeager, M., Wang, H., Shughrue, P., Kinney, G., and Joyce, J. G. (2006) Solution state characterization of amyloid β-derived diffusible ligands. Biochemistry 45, 15157-15167
-
(2006)
Biochemistry
, vol.45
, pp. 15157-15167
-
-
Hepler, R.W.1
Grimm, K.M.2
Nahas, D.D.3
Breese, R.4
Dodson, E.C.5
Acton, P.6
Keller, P.M.7
Yeager, M.8
Wang, H.9
Shughrue, P.10
Kinney, G.11
Joyce, J.G.12
-
11
-
-
79953133327
-
Aβ42 neurotoxicity is mediated by ongoing nucleated polymerization process rather than by discrete Aβ42 species
-
Jan, A., Adolfsson, O., Allaman, I., Buccarello, A. L., Magistretti, P. J., Pfeifer, A., Muhs, A., and Lashuel, H. A. (2011) Aβ42 neurotoxicity is mediated by ongoing nucleated polymerization process rather than by discrete Aβ42 species. J. Biol. Chem. 286, 8585-8596
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 8585-8596
-
-
Jan, A.1
Adolfsson, O.2
Allaman, I.3
Buccarello, A.L.4
Magistretti, P.J.5
Pfeifer, A.6
Muhs, A.7
Lashuel, H.A.8
-
12
-
-
79959887638
-
A diversity of assembly mechanisms of a generic amyloid fold
-
Eichner, T., and Radford, S. E. (2011) A diversity of assembly mechanisms of a generic amyloid fold. Mol. Cell 43, 8-18
-
(2011)
Mol. Cell
, vol.43
, pp. 8-18
-
-
Eichner, T.1
Radford, S.E.2
-
13
-
-
80052555139
-
Metastability of native proteins and the phenomenon of amyloid formation
-
Baldwin, A. J., Knowles, T. P., Tartaglia, G. G., Fitzpatrick, A. W., Devlin, G. L., Shammas, S. L., Waudby, C. A., Mossuto, M. F., Meehan, S., Gras, S. L., Christodoulou, J., Anthony-Cahill, S. J., Barker, P. D., Vendruscolo, M., and Dobson, C. M. (2011) Metastability of native proteins and the phenomenon of amyloid formation. J. Am. Chem. Soc. 133, 14160-14163
-
(2011)
J. Am. Chem. Soc.
, vol.133
, pp. 14160-14163
-
-
Baldwin, A.J.1
Knowles, T.P.2
Tartaglia, G.G.3
Fitzpatrick, A.W.4
Devlin, G.L.5
Shammas, S.L.6
Waudby, C.A.7
Mossuto, M.F.8
Meehan, S.9
Gras, S.L.10
Christodoulou, J.11
Anthony-Cahill, S.J.12
Barker, P.D.13
Vendruscolo, M.14
Dobson, C.M.15
-
14
-
-
33845665382
-
Selection and characterization of Affibody ligands binding to Alzheimer amyloid β peptides
-
Grönwall, C., Jonsson, A., Lindström, S., Gunneriusson, E., Ståhl, S., and Herne, N. (2007) Selection and characterization of Affibody ligands binding to Alzheimer amyloid β peptides. J. Biotechnol. 128, 162-183
-
(2007)
J. Biotechnol.
, vol.128
, pp. 162-183
-
-
Grönwall, C.1
Jonsson, A.2
Lindström, S.3
Gunneriusson, E.4
Ståhl, S.5
Herne, N.6
-
15
-
-
42449111198
-
Stabilization of a β-hairpin in monomeric Alzheimer's amyloid-β peptide inhibits amyloid formation
-
Hoyer, W., Grönwall, C., Jonsson, A., Ståhl, S., and Härd, T. (2008) Stabilization of a β-hairpin in monomeric Alzheimer's amyloid-β peptide inhibits amyloid formation. Proc. Natl. Acad. Sci. U.S.A. 105, 5099-5104
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 5099-5104
-
-
Hoyer, W.1
Grönwall, C.2
Jonsson, A.3
Ståhl, S.4
Härd, T.5
-
16
-
-
77950579610
-
Sequestration of the Aβ peptide prevents toxicity and promotes degradation in vivo
-
Luheshi, L. M., Hoyer, W., de Barros, T. P., van Dijk Härd, I., Brorsson, A. C., Macao, B., Persson, C., Crowther, D. C., Lomas, D. A., Ståhl, S., Dobson, C. M., and Härd, T. (2010) Sequestration of the Aβ peptide prevents toxicity and promotes degradation in vivo. PLoS Biol. 8, e1000334
-
(2010)
PLoS Biol.
, vol.8
-
-
Luheshi, L.M.1
Hoyer, W.2
De Barros, T.P.3
Van Dijk-Härd, I.4
Brorsson, A.C.5
MacAo, B.6
Persson, C.7
Crowther, D.C.8
Lomas, D.A.9
Ståhl, S.10
Dobson, C.M.11
Härd, T.12
-
17
-
-
77957219390
-
A simple method for site-directed mutagenesis using the polymerase chain reaction
-
Hemsley, A., Arnheim, N., Toney, M. D., Cortopassi, G., and Galas, D. J. (1989) A simple method for site-directed mutagenesis using the polymerase chain reaction. Nucleic Acids Res. 17, 6545-6551
-
(1989)
Nucleic Acids Res.
, vol.17
, pp. 6545-6551
-
-
Hemsley, A.1
Arnheim, N.2
Toney, M.D.3
Cortopassi, G.4
Galas, D.J.5
-
18
-
-
41249098954
-
Interaction of Alzheimer's Aβ peptide with an engineered binding protein-thermodynamics and kinetics of coupled folding-binding
-
Hoyer, W., and Härd, T. (2008) Interaction of Alzheimer's Aβ peptide with an engineered binding protein-thermodynamics and kinetics of coupled folding-binding. J. Mol. Biol. 378, 398-411
-
(2008)
J. Mol. Biol.
, vol.378
, pp. 398-411
-
-
Hoyer, W.1
Härd, T.2
-
19
-
-
58049164489
-
Recombinant amyloid β-peptide production by coexpression with an Affibody ligand
-
Macao, B., Hoyer, W., Sandberg, A., Brorsson, A. C., Dobson, C. M., and Härd, T. (2008) Recombinant amyloid β-peptide production by coexpression with an Affibody ligand. BMC Biotechnol. 8, 82
-
(2008)
BMC Biotechnol.
, vol.8
, pp. 82
-
-
MacAo, B.1
Hoyer, W.2
Sandberg, A.3
Brorsson, A.C.4
Dobson, C.M.5
Härd, T.6
-
20
-
-
0015794613
-
Fluorescence and the location of tryptophan residues in protein molecules
-
Burstein, E. A., Vedenkina, N. S., and Ivkova, M. N. (1973) Fluorescence and the location of tryptophan residues in protein molecules. Photochem. Photobiol. 18, 263-279
-
(1973)
Photochem. Photobiol.
, vol.18
, pp. 263-279
-
-
Burstein, E.A.1
Vedenkina, N.S.2
Ivkova, M.N.3
-
21
-
-
0034667871
-
How to measure and analyze tryptophan fluorescence in membranes properly, and why bother?
-
Ladokhin, A. S., Jayasinghe, S., and White, S. H. (2000) How to measure and analyze tryptophan fluorescence in membranes properly, and why bother? Anal. Biochem. 285, 235-245
-
(2000)
Anal. Biochem.
, vol.285
, pp. 235-245
-
-
Ladokhin, A.S.1
Jayasinghe, S.2
White, S.H.3
-
22
-
-
57149145222
-
The ratio of monomeric to aggregated forms of Aβ40 and Aβ42 is an important determinant of amyloid-β aggregation, fibrillogenesis, and toxicity
-
Jan, A., Gokce, O., Luthi-Carter, R., and Lashuel, H. A. (2008) The ratio of monomeric to aggregated forms of Aβ40 and Aβ42 is an important determinant of amyloid-β aggregation, fibrillogenesis, and toxicity. J. Biol. Chem. 283, 28176-28189
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 28176-28189
-
-
Jan, A.1
Gokce, O.2
Luthi-Carter, R.3
Lashuel, H.A.4
-
23
-
-
83055176454
-
Atomic-resolution dynamics on the surface of amyloid-β protofibrils probed by solution NMR
-
Fawzi, N. L., Ying, J., Ghirlando, R., Torchia, D. A., and Clore, G. M. (2011) Atomic-resolution dynamics on the surface of amyloid-β protofibrils probed by solution NMR. Nature 480, 268-272
-
(2011)
Nature
, vol.480
, pp. 268-272
-
-
Fawzi, N.L.1
Ying, J.2
Ghirlando, R.3
Torchia, D.A.4
Clore, G.M.5
-
24
-
-
36849084640
-
Evidence of fibril-likeβ-sheet structures in a neurotoxic amyloid intermediate of Alzheimer's β-amyloid
-
Chimon, S., Shaibat, M. A., Jones, C. R., Calero, D. C., Aizezi, B., and Ishii, Y. (2007) Evidence of fibril-likeβ-sheet structures in a neurotoxic amyloid intermediate of Alzheimer's β-amyloid. Nat. Struct. Mol. Biol. 14, 1157-1164
-
(2007)
Nat. Struct. Mol. Biol.
, vol.14
, pp. 1157-1164
-
-
Chimon, S.1
Shaibat, M.A.2
Jones, C.R.3
Calero, D.C.4
Aizezi, B.5
Ishii, Y.6
-
25
-
-
28444442999
-
3D structure of Alzheimer's amyloid-β(1-42) fibrils
-
Lührs, T., Ritter, C., Adrian, M., Riek-Loher, D., Bohrmann, B., Döbeli, H., Schubert, D., and Riek, R. (2005) 3D structure of Alzheimer's amyloid-β(1-42) fibrils. Proc. Natl. Acad. Sci. U.S.A. 102, 17342-17347
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 17342-17347
-
-
Lührs, T.1
Ritter, C.2
Adrian, M.3
Riek-Loher, D.4
Bohrmann, B.5
Döbeli, H.6
Schubert, D.7
Riek, R.8
-
26
-
-
30744433878
-
Experimental constraints on quaternary structure in Alzheimer'sβ- amyloid fibrils
-
Petkova, A. T., Yau, W. M., and Tycko, R. (2006) Experimental constraints on quaternary structure in Alzheimer'sβ-amyloid fibrils. Biochemistry 45, 498-512
-
(2006)
Biochemistry
, vol.45
, pp. 498-512
-
-
Petkova, A.T.1
Yau, W.M.2
Tycko, R.3
-
27
-
-
64549140676
-
Structural characterization of a soluble amyloidβ-peptide oligomer
-
Yu, L., Edalji, R., Harlan, J. E., Holzman, T. F., Lopez, A. P., Labkovsky, B., Hillen, H., Barghorn, S., Ebert, U., Richardson, P. L., Miesbauer, L., Solomon, L., Bartley, D., Walter, K., Johnson, R. W., Hajduk, P. J., and Olejniczak, E. T. (2009) Structural characterization of a soluble amyloidβ-peptide oligomer. Biochemistry 48, 1870-1877
-
(2009)
Biochemistry
, vol.48
, pp. 1870-1877
-
-
Yu, L.1
Edalji, R.2
Harlan, J.E.3
Holzman, T.F.4
Lopez, A.P.5
Labkovsky, B.6
Hillen, H.7
Barghorn, S.8
Ebert, U.9
Richardson, P.L.10
Miesbauer, L.11
Solomon, L.12
Bartley, D.13
Walter, K.14
Johnson, R.W.15
Hajduk, P.J.16
Olejniczak, E.T.17
-
28
-
-
67849106670
-
Amyloid-β protein oligomerization and the importance of tetramers and dodecamers in the aetiology of Alzheimer's disease
-
Bernstein, S. L., Dupuis, N. F., Lazo, N. D., Wyttenbach, T., Condron, M. M., Bitan, G., Teplow, D. B., Shea, J. E., Ruotolo, B. T., Robinson, C. V., and Bowers, M. T. (2009) Amyloid-β protein oligomerization and the importance of tetramers and dodecamers in the aetiology of Alzheimer's disease. Nat. Chem. 1, 326-331
-
(2009)
Nat. Chem.
, vol.1
, pp. 326-331
-
-
Bernstein, S.L.1
Dupuis, N.F.2
Lazo, N.D.3
Wyttenbach, T.4
Condron, M.M.5
Bitan, G.6
Teplow, D.B.7
Shea, J.E.8
Ruotolo, B.T.9
Robinson, C.V.10
Bowers, M.T.11
-
29
-
-
55749087363
-
Direct characterization of amyloidogenic oligomers by single-molecule fluorescence
-
Orte, A., Birkett, N. R., Clarke, R. W., Devlin, G. L., Dobson, C. M., and Klenerman, D. (2008) Direct characterization of amyloidogenic oligomers by single-molecule fluorescence. Proc. Natl. Acad. Sci. U.S.A. 105, 14424-14429
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 14424-14429
-
-
Orte, A.1
Birkett, N.R.2
Clarke, R.W.3
Devlin, G.L.4
Dobson, C.M.5
Klenerman, D.6
-
30
-
-
0027715059
-
Dissociation of the peptide/MHCclass i complex: PH dependence and effect of endogenous peptides on the activation energy
-
Ojcius, D. M., Gapin, L., and Kourilsky, P. (1993) Dissociation of the peptide/MHCclass I complex: pH dependence and effect of endogenous peptides on the activation energy. Biochem. Biophys. Res. Commun. 197, 1216-1222
-
(1993)
Biochem. Biophys. Res. Commun.
, vol.197
, pp. 1216-1222
-
-
Ojcius, D.M.1
Gapin, L.2
Kourilsky, P.3
-
31
-
-
0034730166
-
Unbinding forces of single antibody-antigen complexes correlate with their thermal dissociation rates
-
Schwesinger, F., Ros, R., Strunz, T., Anselmetti, D., Güntherodt, H. J., Honegger, A., Jermutus, L., Tiefenauer, L., and Plückthun, A. (2000) Unbinding forces of single antibody-antigen complexes correlate with their thermal dissociation rates. Proc. Natl. Acad. Sci. U.S.A. 97, 9972-9977
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 9972-9977
-
-
Schwesinger, F.1
Ros, R.2
Strunz, T.3
Anselmetti, D.4
Güntherodt, H.J.5
Honegger, A.6
Jermutus, L.7
Tiefenauer, L.8
Plückthun, A.9
-
32
-
-
33746781304
-
Structural differences in Aβ amyloid protofibrils and fibrils mapped by hydrogen exchange-mass spectrometry with on-line proteolytic fragmentation
-
Kheterpal, I., Chen, M., Cook, K. D., and Wetzel, R. (2006) Structural differences in Aβ amyloid protofibrils and fibrils mapped by hydrogen exchange-mass spectrometry with on-line proteolytic fragmentation. J. Mol. Biol. 361, 785-795
-
(2006)
J. Mol. Biol.
, vol.361
, pp. 785-795
-
-
Kheterpal, I.1
Chen, M.2
Cook, K.D.3
Wetzel, R.4
-
33
-
-
0345060507
-
Aβ protofibrils possess a stable core structure resistant to hydrogen exchange
-
Kheterpal, I., Lashuel, H. A., Hartley, D. M., Walz, T., Lansbury, P. T., Jr., and Wetzel, R. (2003) Aβ protofibrils possess a stable core structure resistant to hydrogen exchange. Biochemistry 42, 14092-14098
-
(2003)
Biochemistry
, vol.42
, pp. 14092-14098
-
-
Kheterpal, I.1
Lashuel, H.A.2
Hartley, D.M.3
Walz, T.4
Lansbury Jr., P.T.5
Wetzel, R.6
-
34
-
-
84877258447
-
Polymorph-specific kinetics and thermodynamics of β-amyloid fibril growth
-
Qiang, W., Kelley, K., and Tycko, R. (2013) Polymorph-specific kinetics and thermodynamics of β-amyloid fibril growth. J. Am. Chem. Soc. 135, 6860-6871
-
(2013)
J. Am. Chem. Soc.
, vol.135
, pp. 6860-6871
-
-
Qiang, W.1
Kelley, K.2
Tycko, R.3
-
35
-
-
1642633056
-
Conformational variations in an infectious protein determine prion strain differences
-
Tanaka, M., Chien, P., Naber, N., Cooke, R., and Weissman, J. S. (2004) Conformational variations in an infectious protein determine prion strain differences. Nature 428, 323-328
-
(2004)
Nature
, vol.428
, pp. 323-328
-
-
Tanaka, M.1
Chien, P.2
Naber, N.3
Cooke, R.4
Weissman, J.S.5
-
36
-
-
0037422540
-
Amyloid β-protein (Aβ) assembly: Aβ40 and Aβ42 oligomerize through distinct pathways
-
Bitan, G., Kirkitadze, M. D., Lomakin, A., Vollers, S. S., Benedek, G. B., and Teplow, D. B. (2003) Amyloid β-protein (Aβ) assembly: Aβ40 and Aβ42 oligomerize through distinct pathways. Proc. Natl. Acad. Sci. U.S.A. 100, 330-335
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 330-335
-
-
Bitan, G.1
Kirkitadze, M.D.2
Lomakin, A.3
Vollers, S.S.4
Benedek, G.B.5
Teplow, D.B.6
-
37
-
-
0034733023
-
Alzheimer's disease amyloid propagation by a template-dependent dock-lock mechanism
-
Esler, W. P., Stimson, E. R., Jennings, J. M., Vinters, H. V., Ghilardi, J. R., Lee, J. P., Mantyh, P. W., and Maggio, J. E. (2000) Alzheimer's disease amyloid propagation by a template-dependent dock-lock mechanism. Biochemistry 39, 6288-6295
-
(2000)
Biochemistry
, vol.39
, pp. 6288-6295
-
-
Esler, W.P.1
Stimson, E.R.2
Jennings, J.M.3
Vinters, H.V.4
Ghilardi, J.R.5
Lee, J.P.6
Mantyh, P.W.7
Maggio, J.E.8
-
38
-
-
84855450514
-
The extracellular chaperone clusterin sequesters oligomeric forms of the amyloid-β(1-40) peptide
-
Narayan, P., Orte, A., Clarke, R. W., Bolognesi, B., Hook, S., Ganzinger, K. A., Meehan, S., Wilson, M. R., Dobson, C. M., and Klenerman, D. (2012) The extracellular chaperone clusterin sequesters oligomeric forms of the amyloid-β(1-40) peptide. Nat. Struct. Mol. Biol. 19, 79-83
-
(2012)
Nat. Struct. Mol. Biol.
, vol.19
, pp. 79-83
-
-
Narayan, P.1
Orte, A.2
Clarke, R.W.3
Bolognesi, B.4
Hook, S.5
Ganzinger, K.A.6
Meehan, S.7
Wilson, M.R.8
Dobson, C.M.9
Klenerman, D.10
-
39
-
-
79955406741
-
Aβ40 and Aβ42 amyloid fibrils exhibit distinct molecular recycling properties
-
Sánchez, L., Madurga, S., Pukala, T., Vilaseca, M., López-Iglesias, C., Robinson, C. V., Giralt, E., and Carulla, N. (2011) Aβ40 and Aβ42 amyloid fibrils exhibit distinct molecular recycling properties. J. Am. Chem. Soc. 133, 6505-6508
-
(2011)
J. Am. Chem. Soc.
, vol.133
, pp. 6505-6508
-
-
Sánchez, L.1
Madurga, S.2
Pukala, T.3
Vilaseca, M.4
López-Iglesias, C.5
Robinson, C.V.6
Giralt, E.7
Carulla, N.8
-
40
-
-
79952796718
-
Aromatic small molecules remodel toxic soluble oligomers of amyloid β through three independent pathways
-
Ladiwala, A. R., Dordick, J. S., and Tessier, P. M. (2011) Aromatic small molecules remodel toxic soluble oligomers of amyloid β through three independent pathways. J. Biol. Chem. 286, 3209-3218
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 3209-3218
-
-
Ladiwala, A.R.1
Dordick, J.S.2
Tessier, P.M.3
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