Custom cerium oxide nanoparticles protect against a free radical mediated autoimmune degenerative disease in the brain

ACS Nano

Volumn 7, Issue 12, 2013, Pages 10582-10596

  Heckman, Karin L ^a   Decoteau, William ^a   Estevez, Ana ^a   Reed, Kenneth J ^b   Costanzo, Wendi ^b   Sanford, David ^b   Leiter, James C ^c   Clauss, Jennifer ^a   Knapp, Kylie ^a   Gomez, Carlos ^a   Mullen, Patrick ^a   Rathbun, Elle ^a   Prime, Kelly ^a   Marini, Jessica ^a   Patchefsky, Jamie ^a   Patchefsky, Arthur S ^d   Hailstone, Richard K ^e   Erlichman, Joseph S ^a  

^a ST LAWRENCE UNIVERSITY   (United States)

^b Cerion Enterprises   (United States)

^c DARTMOUTH MEDICAL SCHOOL   (United States)

^d Fox Chase Medical Center   (United States)

^e ROCHESTER INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

blood brain barrier; experimental autoimmune encephalitis; free radicals; nanoparticles; tissue distribution

Indexed keywords

BIOLOGICAL APPLICATIONS; BLOOD-BRAIN BARRIER; CERIUM OXIDE NANOPARTICLE; DEGENERATIVE DISEASE; EXPERIMENTAL AUTOIMMUNE ENCEPHALITIS; POTENT ANTIOXIDANTS; REACTIVE OXYGEN SPECIES; TISSUE DISTRIBUTIONS;

CERIUM COMPOUNDS; INDUSTRIAL APPLICATIONS; IONIC STRENGTH; MAMMALS; NANOPARTICLES; OXIDES; SYNTHESIS (CHEMICAL);

FREE RADICALS;

ANTIOXIDANT; CERIC OXIDE; CERIUM; DRUG CARRIER; FREE RADICAL; ION; METAL NANOPARTICLE; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE;

ANIMAL; ARTICLE; AUTOIMMUNE DISEASE; BLOOD BRAIN BARRIER; BRAIN; C57BL MOUSE; CHEMISTRY; DEGENERATIVE DISEASE; DISEASE MODEL; DRUG EFFECT; FEMALE; LIVER; MICROCIRCULATION; MOTOR PERFORMANCE; MOUSE; MULTIPLE SCLEROSIS; NANOMEDICINE; OXIDATIVE STRESS; RAT; SPLEEN; SPRAGUE DAWLEY RAT; TISSUE DISTRIBUTION;

ANIMALS; ANTIOXIDANTS; AUTOIMMUNE DISEASES; BLOOD-BRAIN BARRIER; BRAIN; CERIUM; DISEASE MODELS, ANIMAL; DRUG CARRIERS; FEMALE; FREE RADICALS; IONS; LIVER; METAL NANOPARTICLES; MICE; MICE, INBRED C57BL; MICROCIRCULATION; MOTOR SKILLS; MULTIPLE SCLEROSIS; NANOMEDICINE; NEURODEGENERATIVE DISEASES; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN SPECIES; SPLEEN; TISSUE DISTRIBUTION;

EID: 84891358772     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn403743b     Document Type: Article

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