Brain distribution and toxicological evaluation of a systemically delivered engineered nanoscale ceria

Toxicological Sciences

Volumn 116, Issue 2, 2010, Pages 562-576

  Hardas, Sarita S ^a   Butterfield, David Allan ^a   Sultana, Rukhsana ^a   Tseng, Michael T ^b   Dan, Mo ^a   Florence, Rebecca L ^a   Unrine, Jason M ^c   Graham, Uschi M ^a   Wu, Peng ^d   Grulke, Eric A ^d   Yokel, Robert A ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

^b University of Louisville School of Medicine   (United States)

^c UNIVERSITY OF KENTUCKY   (United States)

^d UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Blood brain barrier; Ceria; Hippocampus; Neurotoxicity; Oxidative injury; Rat

Indexed keywords

3 NITROTYROSINE; ANTIOXIDANT; CARBONYL DERIVATIVE; CATALASE; CERIUM OXIDE; FLUORESCEIN SODIUM; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; HORSERADISH PEROXIDASE; MANGANESE SUPEROXIDE DISMUTASE; NANOMATERIAL; CERIC OXIDE; CERIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATOMIC EMISSION SPECTROMETRY; BLOOD BRAIN BARRIER; BRAIN BLOOD VESSEL; CEREBELLUM; CONTROLLED STUDY; DISPERSION; ELECTRON ENERGY LOSS SPECTROSCOPY; ELECTRON MICROSCOPY; HIPPOCAMPUS; IN VITRO STUDY; MALE; MEMBRANE PERMEABILITY; NANOANALYSIS; NONHUMAN; OXIDATIVE STRESS; RAT; TOXICOLOGICAL PARAMETERS; ANIMAL; BRAIN; DRUG EFFECTS; METABOLISM; PH; SPRAGUE DAWLEY RAT; TOXICITY;

ANIMALS; BLOOD-BRAIN BARRIER; BRAIN; CATALASE; CERIUM; HYDROGEN-ION CONCENTRATION; MALE; NANOSTRUCTURES; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 77955060907     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfq137     Document Type: Article

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