The signaling network that silences the spindle assembly checkpoint upon the establishment of chromosome bipolar attachment

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 52, 2013, Pages 21036-21041

  Jin, Fengzhi ^a   Wang, Yanchang ^a  

^a FLORIDA STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DUO1 AND MPS1 INTERACTING PROTEIN; PHOSPHOPROTEIN PHOSPHATASE 1; PROTEIN; PROTEIN IPL1; PROTEIN SHUGOSHIN; UNCLASSIFIED DRUG;

ANAPHASE; ARTICLE; CELL SYNCHRONIZATION; CENTROMERE; CONTROLLED STUDY; INTRACELLULAR SIGNALING; M PHASE CELL CYCLE CHECKPOINT; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; YEAST CELL;

EID: 84891358063     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1307595111     Document Type: Article

References (26)

1. Hoyt MA, Totis L, Roberts BT (1991) S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function. Cell 66(3): 507-517.
2. Li R, Murray AW (1991) Feedback control of mitosis in budding yeast. Cell 66(3): 519-531.
3. Hardwick KG, Weiss E, Luca FC, Winey M, Murray AW (1996) Activation of the budding yeast spindle assembly checkpoint without mitotic spindle disruption. Science 273(5277): 953-956.
4. Gillett ES, Espelin CW, Sorger PK (2004) Spindle checkpoint proteins and chromosomemicrotubule attachment in budding yeast. J Cell Biol 164(4): 535-546.
5. Chen RH, Waters JC, Salmon ED, Murray AW (1996) Association of spindle assembly checkpoint component XMAD2 with unattached kinetochores. Science 274(5285): 242-246.
6. Cohen-Fix O, Peters JM, Kirschner MW, Koshland D (1996) Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p. Genes Dev 10(24): 3081-3093.
7. Biggins S, Murray AW (2001) The budding yeast protein kinase Ipl1/Aurora allows the absence of tension to activate the spindle checkpoint. Genes Dev 15(23): 3118-3129.
8. Indjeian VB, Stern BM, Murray AW (2005) The centromeric protein Sgo1 is required to sense lack of tension on mitotic chromosomes. Science 307(5706): 130-133.
9. Jin F, Liu H, Li P, Yu HG, Wang Y (2012) Loss of function of the Cik1/Kar3 motor complex results in chromosomes with syntelic attachment that are sensed by the tension checkpoint. PLoS Genet 8(2):e1002492.
10. Pinsky BA, Kung C, Shokat KM, Biggins S (2006) The Ipl1-Aurora protein kinase activates the spindle checkpoint by creating unattached kinetochores. Nat Cell Biol 8(1): 78-83.
11. Tanaka TU, et al. (2002) Evidence that the Ipl1-Sli15 (Aurora kinase-INCENP) complex promotes chromosome bi-orientation by altering kinetochore-spindle pole connections. Cell 108(3): 317-329.
12. Westhorpe FG, Tighe A, Lara-Gonzalez P, Taylor SS (2011) p31comet-mediated extraction of Mad2 from the MCC promotes efficient mitotic exit. J Cell Sci 124(Pt 22): 3905-3916.
13. Howell BJ, et al. (2001) Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivation. J Cell Biol 155(7): 1159-1172.
14. Vanoosthuyse V, Hardwick KG (2009) A novel protein phosphatase 1-dependent spindle checkpoint silencing mechanism. Curr Biol 19(14): 1176-1181.
15. Pinsky BA, Nelson CR, Biggins S (2009) Protein phosphatase 1 regulates exit from the spindle checkpoint in budding yeast. Curr Biol 19(14): 1182-1187.
16. Hardwick KG, Murray AW (1995) Mad1p, a phosphoprotein component of the spindle assembly checkpoint in budding yeast. J Cell Biol 131(3): 709-720.
17. Mirchenko L, Uhlmann F (2010) Sli15(INCENP) dephosphorylation prevents mitotic checkpoint reengagement due to loss of tension at anaphase onset. Curr Biol 20(15): 1396-1401.
18. Liu H, Jin F, Liang F, Tian X, Wang Y (2011) The Cik1/Kar3 motor complex is required for the proper kinetochore-microtubule interaction after stressful DNA replication. Genetics 187(2): 397-407.
19. Cheeseman IM, et al. (2002) Phospho-regulation of kinetochore-microtubule attachments by the Aurora kinase Ipl1p. Cell 111(2): 163-172.
20. Farr KA, Hoyt MA (1998) Bub1p kinase activates the Saccharomyces cerevisiae spindle assembly checkpoint. Mol Cell Biol 18(5): 2738-2747.
21. Brady DM, Hardwick KG (2000) Complex formation between Mad1p, Bub1p and Bub3p is crucial for spindle checkpoint function. Curr Biol 10(11): 675-678.
22. Hieter P, Mann C, Snyder M, Davis RW (1985) Mitotic stability of yeast chromosomes: A colony color assay that measures nondisjunction and chromosome loss. Cell 40(2): 381-392.
23. Liang F, Wang Y (2007) DNA damage checkpoints inhibit mitotic exit by two different mechanisms. Mol Cell Biol 27(14): 5067-5078.
24. Meadows JC, et al. (2011) Spindle checkpoint silencing requires association of PP1 to both Spc7 and kinesin-8 motors. Dev Cell 20(6): 739-750.
25. Rosenberg JS, Cross FR, Funabiki H (2011) KNL1/Spc105 recruits PP1 to silence the spindle assembly checkpoint. Curr Biol 21(11): 942-947.
26. Keating P, Rachidi N, Tanaka TU, Stark MJ (2009) Ipl1-dependent phosphorylation of Dam1 is reduced by tension applied on kinetochores. J Cell Sci 122(Pt 23): 4375-4382.