Ryanodine receptor phosphorylation by oxidized CaMKII contributes to the cardiotoxic effects of cardiac glycosides

Cardiovascular Research

Volumn 101, Issue 1, 2014, Pages 165-174

  Ho, Hsiang Ting ^a,b   Liu, Bin ^a,b   Snyder, Jedidiah S ^b   Lou, Qing ^a,b   Brundage, Elizabeth A ^a,b   Velez Cortes, Florencia ^a,b   Wang, Honglan ^a,b   Ziolo, Mark T ^a,b   Anderson, Mark E ^c   Sen, Chandan K ^a,b   Wehrens, Xander H T ^d   Fedorov, Vadim V ^a,b   Biesiadecki, Brandon J ^a,b   Hund, Thomas J ^b,e   Györke, Sándor ^a,b  

^a OHIO STATE UNIVERSITY   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c UNIVERSITY OF IOWA   (United States)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

^e Ohio State University   (United States)

Author keywords

Calcium; CaMKII; Mitochondria; NADPH oxidase; Reactive oxygen species

Indexed keywords

CALCIUM; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CARDIAC GLYCOSIDE; DIGITOXIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; RYANODINE RECEPTOR; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ARRHYTHMOGENESIS; ARTICLE; CARDIOTOXICITY; CONTROLLED STUDY; DEPOLARIZATION; HEART MUSCLE CELL; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; WESTERN BLOTTING;

CALCIUM; CAMKII; MITOCHONDRIA; NADPH OXIDASE; REACTIVE OXYGEN SPECIES;

ANIMALS; ANTI-ARRHYTHMIA AGENTS; ARRHYTHMIAS, CARDIAC; CALCIUM; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; DIGITOXIN; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICE, KNOCKOUT; MYOCYTES, CARDIAC; NADPH OXIDASE; PHOSPHORYLATION; REACTIVE OXYGEN SPECIES; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SUPEROXIDE DISMUTASE;

EID: 84891351174     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvt233     Document Type: Article

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