-
1
-
-
0035733762
-
Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease
-
Backman SA, Stambolic V, Suzuki A, Haight J, Elia A, Pretorius J, Tsao MS, Shannon P, Bolon B, Ivy GO, et al. 2001. Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease. Nat Genet 29: 396-403.
-
(2001)
Nat Genet
, vol.29
, pp. 396-403
-
-
Backman, S.A.1
Stambolic, V.2
Suzuki, A.3
Haight, J.4
Elia, A.5
Pretorius, J.6
Tsao, M.S.7
Shannon, P.8
Bolon, B.9
Ivy, G.O.10
-
2
-
-
3042647610
-
The mGluR theory of fragile X mental retardation
-
Bear MF, Huber KM, Warren ST. 2004. The mGluR theory of fragile X mental retardation. Trends Neurosci 27: 370-377.
-
(2004)
Trends Neurosci
, vol.27
, pp. 370-377
-
-
Bear, M.F.1
Huber, K.M.2
Warren, S.T.3
-
3
-
-
84867736998
-
Genetic removal of p70 S6 kinase 1 corrects molecular, synaptic, and behavioral phenotypes in fragile X syndrome mice
-
Bhattacharya A, Kaphzan H, Alvarez-Dieppa AC, Murphy JP, Pierre P, Klann E. 2012. Genetic removal of p70 S6 kinase 1 corrects molecular, synaptic, and behavioral phenotypes in fragile X syndrome mice. Neuron 76: 325-337.
-
(2012)
Neuron
, vol.76
, pp. 325-337
-
-
Bhattacharya, A.1
Kaphzan, H.2
Alvarez-Dieppa, A.C.3
Murphy, J.P.4
Pierre, P.5
Klann, E.6
-
4
-
-
84870317549
-
Novel PTEN germline mutation in a family with mild phenotype: Difficulties in genetic counseling
-
Busa T, Chabrol B, Perret O, Longy M, Philip N. 2013. Novel PTEN germline mutation in a family with mild phenotype: Difficulties in genetic counseling. Gene 512: 194-197.
-
(2013)
Gene
, vol.512
, pp. 194-197
-
-
Busa, T.1
Chabrol, B.2
Perret, O.3
Longy, M.4
Philip, N.5
-
5
-
-
20244367771
-
Subset of individuals with autism spectrum disorders and extreme macrocephaly associated with germline PTEN tumour suppressor gene mutations
-
Butler MG, Dasouki MJ, Zhou XP, Talebizadeh Z, Brown M, Takahashi TN, Miles JH, Wang CH, Stratton R, Pilarski R, et al. 2005. Subset of individuals with autism spectrum disorders and extreme macrocephaly associated with germline PTEN tumour suppressor gene mutations. J Med Genet 42: 318-321.
-
(2005)
J Med Genet
, vol.42
, pp. 318-321
-
-
Butler, M.G.1
Dasouki, M.J.2
Zhou, X.P.3
Talebizadeh, Z.4
Brown, M.5
Takahashi, T.N.6
Miles, J.H.7
Wang, C.H.8
Stratton, R.9
Pilarski, R.10
-
6
-
-
34250812575
-
Mutation screening of the PTEN gene in patients with autism spectrum disorders and macrocephaly
-
Buxbaum JD, Cai G, Chaste P, Nygren G, Goldsmith J, Reichert J, Anckarsater H, Rastam M, Smith CJ, Silverman JM, et al. 2007. Mutation screening of the PTEN gene in patients with autism spectrum disorders and macrocephaly. Am J Med Genet B Neuropsychiatr Genet 144B: 484-491.
-
(2007)
Am J Med Genet B Neuropsychiatr Genet
, vol.144 B
, pp. 484-491
-
-
Buxbaum, J.D.1
Cai, G.2
Chaste, P.3
Nygren, G.4
Goldsmith, J.5
Reichert, J.6
Anckarsater, H.7
Rastam, M.8
Smith, C.J.9
Silverman, J.M.10
-
7
-
-
84856354305
-
In vivo neuronal function of the fragile X mental retardation protein is regulated by phosphorylation
-
Coffee RL Jr, Williamson AJ, Adkins CM, Gray MC, Page TL, Broadie K. 2012. In vivo neuronal function of the fragile X mental retardation protein is regulated by phosphorylation. Hum Mol Genet 21: 900-915.
-
(2012)
Hum Mol Genet
, vol.21
, pp. 900-915
-
-
Coffee Jr., R.L.1
Williamson, A.J.2
Adkins, C.M.3
Gray, M.C.4
Page, T.L.5
Broadie, K.6
-
9
-
-
49149088555
-
Reversal of learning deficits in a Tsc2+/- mouse model of tuberous sclerosis
-
Ehninger D, Han S, Shilyansky C, Zhou Y, LiW, Kwiatkowski DJ, Ramesh V, Silva AJ. 2008. Reversal of learning deficits in a Tsc2+/- mouse model of tuberous sclerosis. Nat Med 14: 843-848.
-
(2008)
Nat Med
, vol.14
, pp. 843-848
-
-
Ehninger, D.1
Han, S.2
Shilyansky, C.3
Zhou, Y.4
Li, W.5
Kwiatkowski, D.J.6
Ramesh, V.7
Silva, A.J.8
-
10
-
-
51849130466
-
PTEN signaling in brain: Neuropathology and tumorigenesis
-
Endersby R, Baker SJ. 2008. PTEN signaling in brain: Neuropathology and tumorigenesis. Oncogene 27: 5416-5430.
-
(2008)
Oncogene
, vol.27
, pp. 5416-5430
-
-
Endersby, R.1
Baker, S.J.2
-
11
-
-
0033153226
-
Why we think plasticity underlying Pavlovian fear conditioning occurs in the basolateral amygdala
-
Fanselow MS, LeDoux JE. 1999. Why we think plasticity underlying Pavlovian fear conditioning occurs in the basolateral amygdala. Neuron 23: 229-232.
-
(1999)
Neuron
, vol.23
, pp. 229-232
-
-
Fanselow, M.S.1
Ledoux, J.E.2
-
12
-
-
37849027524
-
Phosphatase and tensin homolog, deleted on chromosome 10 deficiency in brain causes defects in synaptic structure, transmission and plasticity, and myelination abnormalities
-
Fraser MM, Bayazitov IT, Zakharenko SS, Baker SJ. 2008. Phosphatase and tensin homolog, deleted on chromosome 10 deficiency in brain causes defects in synaptic structure, transmission and plasticity, and myelination abnormalities. Neuroscience 151: 476-488.
-
(2008)
Neuroscience
, vol.151
, pp. 476-488
-
-
Fraser, M.M.1
Bayazitov, I.T.2
Zakharenko, S.S.3
Baker, S.J.4
-
13
-
-
0035828080
-
PTEN mutation in a family with Cowden syndrome and autism
-
Goffin A, Hoefsloot LH, Bosgoed E, Swillen A, Fryns JP. 2001. PTEN mutation in a family with Cowden syndrome and autism. Am J Med Genet 105: 521-524.
-
(2001)
Am J Med Genet
, vol.105
, pp. 521-524
-
-
Goffin, A.1
Hoefsloot, L.H.2
Bosgoed, E.3
Swillen, A.4
Fryns, J.P.5
-
14
-
-
75749114797
-
MTOR signaling: At the crossroads of plasticity, memory and disease
-
Hoeffer CA, Klann E. 2010. mTOR signaling: At the crossroads of plasticity, memory and disease. Trends Neurosci 33: 67-75.
-
(2010)
Trends Neurosci
, vol.33
, pp. 67-75
-
-
Hoeffer, C.A.1
Klann, E.2
-
15
-
-
0037188502
-
Altered synaptic plasticity in a mouse model of fragile X mental retardation
-
Huber KM, Gallagher SM, Warren ST, Bear MF. 2002. Altered synaptic plasticity in a mouse model of fragile X mental retardation. Proc Natl Acad Sci 99: 7746-7750.
-
(2002)
Proc Natl Acad Sci
, vol.99
, pp. 7746-7750
-
-
Huber, K.M.1
Gallagher, S.M.2
Warren, S.T.3
Bear, M.F.4
-
16
-
-
77955850746
-
PTEN is recruited to the postsynaptic terminal for NMDA receptor-dependent long-term depression
-
Jurado S, Benoist M, Lario A, Knafo S, Petrok CN, Esteban JA. 2010. PTEN is recruited to the postsynaptic terminal for NMDA receptor-dependent long-term depression. EMBO J 29: 2827-2840.
-
(2010)
EMBO J
, vol.29
, pp. 2827-2840
-
-
Jurado, S.1
Benoist, M.2
Lario, A.3
Knafo, S.4
Petrok, C.N.5
Esteban, J.A.6
-
17
-
-
84866273318
-
Development and characterization of NEX-Pten, a novel forebrain excitatory neuron-specific knockout mouse
-
Kazdoba TM, Sunnen CN, Crowell B, Lee GH, Anderson AE, D'Arcangelo G. 2012. Development and characterization of NEX-Pten, a novel forebrain excitatory neuron-specific knockout mouse. Dev Neurosci 34: 198-209.
-
(2012)
Dev Neurosci
, vol.34
, pp. 198-209
-
-
Kazdoba, T.M.1
Sunnen, C.N.2
Crowell, B.3
Lee, G.H.4
Anderson, A.E.5
D'Arcangelo, G.6
-
18
-
-
0026514823
-
Modality-specific retrograde amnesia of fear
-
Kim JJ, Fanselow MS. 1992. Modality-specific retrograde amnesia of fear. Science 256: 675-677.
-
(1992)
Science
, vol.256
, pp. 675-677
-
-
Kim, J.J.1
Fanselow, M.S.2
-
19
-
-
0035734381
-
Pten regulates neuronal soma size: A mouse model of Lhermitte-Duclos disease
-
Kwon CH, Zhu X, Zhang J, Knoop LL, Tharp R, Smeyne RJ, Eberhart CG, Burger PC, Baker SJ. 2001. Pten regulates neuronal soma size: A mouse model of Lhermitte-Duclos disease. Nat Genet 29: 404-411.
-
(2001)
Nat Genet
, vol.29
, pp. 404-411
-
-
Kwon, C.H.1
Zhu, X.2
Zhang, J.3
Knoop, L.L.4
Tharp, R.5
Smeyne, R.J.6
Eberhart, C.G.7
Burger, P.C.8
Baker, S.J.9
-
20
-
-
33646142995
-
Pten regulates neuronal arborization and social interaction in mice
-
Kwon CH, Luikart BW, Powell CM, Zhou J, Matheny SA, Zhang W, Li Y, Baker SJ, Parada LF. 2006. Pten regulates neuronal arborization and social interaction in mice. Neuron 50: 377-388.
-
(2006)
Neuron
, vol.50
, pp. 377-388
-
-
Kwon, C.H.1
Luikart, B.W.2
Powell, C.M.3
Zhou, J.4
Matheny, S.A.5
Zhang, W.6
Li, Y.7
Baker, S.J.8
Parada, L.F.9
-
21
-
-
0035864826
-
Evidence that fragile X mental retardation protein is a negative regulator of translation
-
Laggerbauer B, Ostareck D, Keidel EM, Ostareck-Lederer A, Fischer U. 2001. Evidence that fragile X mental retardation protein is a negative regulator of translation. Hum Mol Genet 10: 329-338.
-
(2001)
Hum Mol Genet
, vol.10
, pp. 329-338
-
-
Laggerbauer, B.1
Ostareck, D.2
Keidel, E.M.3
Ostareck-Lederer, A.4
Fischer, U.5
-
22
-
-
0032929762
-
Signalling through phosphoinositide 3-kinases: The lipids take centre stage
-
Leevers SJ, Vanhaesebroeck B, Waterfield MD. 1999. Signalling through phosphoinositide 3-kinases: The lipids take centre stage. Curr Opin Cell Biol 11: 219-225.
-
(1999)
Curr Opin Cell Biol
, vol.11
, pp. 219-225
-
-
Leevers, S.J.1
Vanhaesebroeck, B.2
Waterfield, M.D.3
-
23
-
-
0035368955
-
The fragile X mental retardation protein inhibits translation via interacting with mRNA
-
Li Z, Zhang Y, Ku L, Wilkinson KD, Warren ST, Feng Y. 2001. The fragile X mental retardation protein inhibits translation via interacting with mRNA. Nucleic Acids Res 29: 2276-2283.
-
(2001)
Nucleic Acids Res
, vol.29
, pp. 2276-2283
-
-
Li, Z.1
Zhang, Y.2
Ku, L.3
Wilkinson, K.D.4
Warren, S.T.5
Feng, Y.6
-
24
-
-
48749126744
-
Altered phosphorylation and localization of the A-type channel, Kv4.2 in status epilepticus
-
Lugo JN, Barnwell LF, Ren Y, Lee WL, Johnston LD, Kim R, Hrachovy RA, Sweatt JD, Anderson AE. 2008. Altered phosphorylation and localization of the A-type channel, Kv4.2 in status epilepticus. J Neurochem 106: 1929-1940.
-
(2008)
J Neurochem
, vol.106
, pp. 1929-1940
-
-
Lugo, J.N.1
Barnwell, L.F.2
Ren, Y.3
Lee, W.L.4
Johnston, L.D.5
Kim, R.6
Hrachovy, R.A.7
Sweatt, J.D.8
Anderson, A.E.9
-
25
-
-
84861124663
-
Kv4.2 knockout mice have hippocampal-dependent learning and memory deficits
-
Lugo JN, Brewster AL, Spencer CM, Anderson AE. 2012. Kv4.2 knockout mice have hippocampal-dependent learning and memory deficits. Learn Mem 19: 182-189.
-
(2012)
Learn Mem
, vol.19
, pp. 182-189
-
-
Lugo, J.N.1
Brewster, A.L.2
Spencer, C.M.3
Anderson, A.E.4
-
26
-
-
0032577699
-
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
-
Maehama T, Dixon JE. 1998. The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem 273: 13375-13378.
-
(1998)
J Biol Chem
, vol.273
, pp. 13375-13378
-
-
Maehama, T.1
Dixon, J.E.2
-
27
-
-
0026635574
-
Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning
-
Phillips RG, LeDoux JE. 1992. Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning. Behav Neurosci 106: 274-285.
-
(1992)
Behav Neurosci
, vol.106
, pp. 274-285
-
-
Phillips, R.G.1
Ledoux, J.E.2
-
28
-
-
79251634440
-
Double dissociation of amygdala and hippocampal contributions to trace and delay fear conditioning
-
Raybuck JD, Lattal KM. 2011. Double dissociation of amygdala and hippocampal contributions to trace and delay fear conditioning. PLoS One 6: e15982.
-
(2011)
PLoS One
, vol.6
-
-
Raybuck, J.D.1
Lattal, K.M.2
-
29
-
-
74949102875
-
Dysregulation of mTOR signaling in fragile X syndrome
-
Sharma A, Hoeffer CA, Takayasu Y, Miyawaki T, McBride SM, Klann E, Zukin RS. 2010. Dysregulation of mTOR signaling in fragile X syndrome. J Neurosci 30: 694-702.
-
(2010)
J Neurosci
, vol.30
, pp. 694-702
-
-
Sharma, A.1
Hoeffer, C.A.2
Takayasu, Y.3
Miyawaki, T.4
McBride, S.M.5
Klann, E.6
Zukin, R.S.7
-
30
-
-
84856904410
-
Phosphatase and tensin homologue (PTEN) regulates synaptic plasticity independently of its effect on neuronal morphology and migration
-
Sperow M, Berry RB, Bayazitov IT, Zhu G, Baker SJ, Zakharenko SS. 2012. Phosphatase and tensin homologue (PTEN) regulates synaptic plasticity independently of its effect on neuronal morphology and migration. J Physiol 590: 777-792.
-
(2012)
J Physiol
, vol.590
, pp. 777-792
-
-
Sperow, M.1
Berry, R.B.2
Bayazitov, I.T.3
Zhu, G.4
Baker, S.J.5
Zakharenko, S.S.6
-
31
-
-
79952763934
-
Selective pharmacogenetic inhibition of mammalian target of Rapamycin complex i (mTORC1) blocks long-term synaptic plasticity and memory storage
-
Stoica L, Zhu PJ, Huang W, Zhou H, Kozma SC, Costa-Mattioli M. 2011. Selective pharmacogenetic inhibition of mammalian target of Rapamycin complex I (mTORC1) blocks long-term synaptic plasticity and memory storage. Proc Natl Acad Sci 108: 3791-3796.
-
(2011)
Proc Natl Acad Sci
, vol.108
, pp. 3791-3796
-
-
Stoica, L.1
Zhu, P.J.2
Huang, W.3
Zhou, H.4
Kozma, S.C.5
Costa-Mattioli, M.6
-
32
-
-
84875270373
-
Dysregulation of synaptic plasticity precedes appearance of morphological defects in a Pten conditional knockout mouse model of autism
-
Takeuchi K, Gertner MJ, Zhou J, Parada LF, Bennett MV, Zukin RS. 2013. Dysregulation of synaptic plasticity precedes appearance of morphological defects in a Pten conditional knockout mouse model of autism. Proc Natl Acad Sci 110: 4738-4743.
-
(2013)
Proc Natl Acad Sci
, vol.110
, pp. 4738-4743
-
-
Takeuchi, K.1
Gertner, M.J.2
Zhou, J.3
Parada, L.F.4
Bennett, M.V.5
Zukin, R.S.6
-
33
-
-
0025905795
-
Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome
-
Verkerk AJ, Pieretti M, Sutcliffe JS, Fu YH, Kuhl DP, Pizzuti A, Reiner O, Richards S, Victoria MF, Zhang FP, et al. 1991. Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome. Cell 65: 905-914.
-
(1991)
Cell
, vol.65
, pp. 905-914
-
-
Verkerk, A.J.1
Pieretti, M.2
Sutcliffe, J.S.3
Fu, Y.H.4
Kuhl, D.P.5
Pizzuti, A.6
Reiner, O.7
Richards, S.8
Victoria, M.F.9
Zhang, F.P.10
-
34
-
-
0036206130
-
Protean PTEN: Form and function
-
Waite KA, Eng C. 2002. Protean PTEN: Form and function. Am J Hum Genet 70: 829-844.
-
(2002)
Am J Hum Genet
, vol.70
, pp. 829-844
-
-
Waite, K.A.1
Eng, C.2
-
35
-
-
33745255079
-
The PTEN phosphatase is essential for long-term depression of hippocampal synapses
-
Wang Y, Cheng A, MattsonMP. 2006. The PTEN phosphatase is essential for long-term depression of hippocampal synapses. Neuromolecular Med 8: 329-336.
-
(2006)
Neuromolecular Med
, vol.8
, pp. 329-336
-
-
Wang, Y.1
Cheng, A.2
Mattson, M.P.3
-
36
-
-
21844432115
-
Trace fear conditioning is enhanced in mice lacking the d subunit of the GABAA receptor
-
Wiltgen BJ, Sanders MJ, Ferguson C, Homanics GE, Fanselow MS. 2005. Trace fear conditioning is enhanced in mice lacking the d subunit of the GABAA receptor. Learn Mem 12: 327-333.
-
(2005)
Learn Mem
, vol.12
, pp. 327-333
-
-
Wiltgen, B.J.1
Sanders, M.J.2
Ferguson, C.3
Homanics, G.E.4
Fanselow, M.S.5
|