Role of CXCR2 and TRPV1 in functional, inflammatory and behavioural changes in the rat model of cyclophosphamide-induced haemorrhagic cystitis

British Journal of Pharmacology

Volumn 171, Issue 2, 2014, Pages 452-467

  Dornelles, Fabiana N ^a   Andrade, Edinéia L ^a   Campos, Maria M ^b   Calixto, João B ^a,c  

^a FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

^b PONTIFICAL CATHOLIC UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^c Centro de Inova ão e Ensaios Pré Clínicos CIEnP   (Brazil)

Author keywords

bladder inflammation; CXCR2 receptors; Cyclophosphamide induced cystitis; pain behaviour; TRPV1 channels; voiding dysfunction

Indexed keywords

1 (2 BROMOPHENYL) 3 (2 HYDROXY 4 NITROPHENYL)UREA; 4 CHLORO N (3 METHOXYPHENYL)CINNAMAMIDE; CHEMOKINE RECEPTOR CXCR2; MESSENGER RNA; VANILLOID RECEPTOR 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR CHANGE; BLADDER CAPACITY; BLADDER DYSFUNCTION; BLADDER PRESSURE; CONTROLLED STUDY; CXCR2 GENE; DRUG TARGETING; FEMALE; GENE EXPRESSION; HEMORRHAGIC CYSTITIS; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; MOLECULAR PATHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRPV1 GENE; URINE VOLUME;

BLADDER INFLAMMATION; CXCR2 RECEPTORS; CYCLOPHOSPHAMIDE-INDUCED CYSTITIS; PAIN BEHAVIOUR; TRPV1 CHANNELS; VOIDING DYSFUNCTION;

ANIMALS; ANTINEOPLASTIC AGENTS, ALKYLATING; BEHAVIOR, ANIMAL; CYCLOPHOSPHAMIDE; CYSTITIS; CYTOKINES; FEMALE; HEMORRHAGIC DISORDERS; HYPERALGESIA; IMMUNOHISTOCHEMISTRY; INFLAMMATION; NEUTROPHILS; ORGAN SIZE; PAIN MEASUREMENT; PEROXIDASE; RATS; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, INTERLEUKIN-8B; TRPV CATION CHANNELS; URINARY BLADDER;

EID: 84891276546     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.12467     Document Type: Article

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