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Volumn 53, Issue 1, 2014, Pages 282-285

The catalytic asymmetric α-benzylation of aldehydes

Author keywords

alkylation; branched aldehydes; DYKATt; enamine catalysis; organocatalysis

Indexed keywords

BRANCHED ALDEHYDES; DYKATT; ENAMINES; HIGH ENANTIOSELECTIVITY; ORGANOCATALYSIS; PROLINE DERIVATIVES; STEREOGENIC CENTERS; STERICALLY DEMANDING;

EID: 84890926781     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201306037     Document Type: Article
Times cited : (75)

References (41)
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    • Houk, Blackmond, and co-workers have shown the advantageous effect of a buffer on reactions catalyzed by proline (derivatives):, J. E. Hein, J. Burs, Y.-h. Lam, M. Hughes, K. N. Houk, A. Armstrong, D. G. Blackmond, Org. Lett. 2011, 13, 5644-5647. Our own NMR-spectroscopic measurements show that the buffer system aids both the catalyst solubilization and the enamine formation, supporting the roles we proposed for base and acid additives. See the Supporting Information, Chapter 7 for details.
    • (2011) Org. Lett. , vol.13 , pp. 5644-5647
    • Hein, J.E.1    Burs, J.2    Lam, Y.-H.3    Hughes, M.4    Houk, K.N.5    Armstrong, A.6    Blackmond, D.G.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.