Organocatalytic enantioselective cascade michael-alkylation reactions: Synthesis of chiral cyclopropanes and investigation of unexpected organocatalyzed stereoselective ring opening of cyclopropanes

Journal of the American Chemical Society

Volumn 129, Issue 35, 2007, Pages 10886-10894

  Xie, Hexin ^a   Zu, Liansuo ^a   Li, Hao ^a   Wang, Jian ^a   Wang, Wei ^a  

^a UNIVERSITY OF NEW MEXICO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BROMOMALONATES; CASCADE PROCESS; LEWIS ACID; MICHAEL-ALKYLATION REACTIONS; MOLECULAR ARCHITECTURES;

CATALYSIS; CATALYSTS; ENANTIOSELECTIVITY; ETHERS; ORGANOMETALLICS; SODIUM COMPOUNDS;

PROPANE;

2,6 DIMETHYLPYRIDINE; ALDEHYDE DERIVATIVE; ALPHA,BETA ALDEHYDE DERIVATIVE; BROMOMALONIC ACID DERIVATIVE; CYCLOPROPANE; DIPHENYLPROLINOL; LEWIS ACID; MALONIC ACID DERIVATIVE; PROLINE DERIVATIVE; UNCLASSIFIED DRUG; CYCLOPROPANE DERIVATIVE;

ALKYLATION; ARTICLE; ASYMMETRIC CATALYSIS; CATALYSIS; CHEMICAL REACTION KINETICS; CHIRALITY; DIASTEREOISOMER; ENANTIOSELECTIVITY; MICHAEL ADDITION; RING OPENING; STEREOCHEMISTRY; SYNTHESIS; CHEMISTRY; CYCLIZATION; STEREOISOMERISM; X RAY CRYSTALLOGRAPHY;

ALKYLATION; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; CYCLIZATION; CYCLOPROPANES; STEREOISOMERISM;

EID: 34848814187     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja073262a     Document Type: Article

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137. The X-ray crystal structure of compound 5k is also available from CCDC-640204. These data can be obtained free of charge via www.ccdc.cam.ac.uk.