Loss of TRPML1 promotes production of reactive oxygen species: Is oxidative damage a factor in mucolipidosis type IV

Biochemical Journal

Volumn 457, Issue 2, 2014, Pages 361-368

  Coblentz, Jessica ^a   St Croix, Claudette ^a   Kiselyov, Kirill ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

Iron; Lysosomal storage disease; Mitochondrion; Reactive oxygen species; Transient receptor potential (TRP) channel

Indexed keywords

REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; TRANSIENT RECEPTOR POTENTIAL CHANNEL; TRANSIENT RECEPTOR POTENTIAL MUCOLIPIN 1; UNCLASSIFIED DRUG;

ARTICLE; AUTOPHAGY; CELL STRUCTURE; CONTROLLED STUDY; HUMAN; HUMAN CELL; LIPID OXIDATION; LIPID PEROXIDATION; LYSOSOME; LYSOSOME STORAGE DISEASE; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MUCOLIPIDOSIS; MUCOLIPIDOSIS TYPE 4; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL; STUDENT T TEST;

EID: 84890909950     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20130647     Document Type: Article

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