Epistasis, pleiotropy, and the mutation load in sexual and asexual populations

Evolution

Volumn 68, Issue 1, 2014, Pages 137-149

  Roze, Denis ^a,b   Blanckaert, Alexandre ^c  

^a STATION BIOLOGIQUE DE ROSCOFF   (France)

^b SORBONNE UNIVERSITÉ   (France)

^c UNIVERSITY OF VIENNA   (Austria)

Author keywords

Adaptive landscape; Epistasis; Evolutionary quantitative genetics; Multilocus models; Mutation load; Stabilizing selection

Indexed keywords

ASEXUAL REPRODUCTION; EPISTASIS; EVOLUTIONARY BIOLOGY; FITNESS; MUTATION; POPULATION SIZE; QUANTITATIVE ANALYSIS; SEXUAL REPRODUCTION;

ADAPTIVE LANDSCAPE; ANIMAL; ARTICLE; ASEXUAL REPRODUCTION; BIOLOGICAL MODEL; EPISTASIS; EVOLUTIONARY QUANTITATIVE GENETICS; GENETIC LOAD; GENETICS; MOLECULAR EVOLUTION; MULTILOCUS MODELS; MUTATION; MUTATION LOAD; PLEIOTROPY; STABILIZING SELECTION;

ADAPTIVE LANDSCAPE; EPISTASIS; EVOLUTIONARY QUANTITATIVE GENETICS; MULTILOCUS MODELS; MUTATION LOAD; STABILIZING SELECTION;

ANIMALS; EPISTASIS, GENETIC; EVOLUTION, MOLECULAR; GENETIC LOAD; GENETIC PLEIOTROPY; MODELS, GENETIC; MUTATION; REPRODUCTION, ASEXUAL;

EID: 84890878459     PISSN: 00143820     EISSN: 15585646     Source Type: Journal    
DOI: 10.1111/evo.12232     Document Type: Article

References (55)

1. Barton, N. H. 1986. The maintenance of polygenic variation through a balance between mutation and stabilizing selection. Genet. Res. 47:209-216.
2. Barton, N. H. 1989. The divergence of a polygenic system subject to stabilizing selection, mutation and drift. Genet. Res. 54:59-77.
3. Barton, N. H. 1995. A general model for the evolution of recombination. Genet. Res. 65:123-144.
4. Barton, N. H., and M. Turelli 1987. Adaptive landscapes, genetic distance and the evolution of quantitative characters. Genet. Res. 49:157-173.
5. Bulmer, M. G. 1971. The effect of selection on genetic variability. Am. Nat. 105:201-211.
6. Bulmer, M. G. 1972. The genetic variability of polygenic characters under optimizing selection, mutation and drift. Genet. Res. 19:17-25.
7. Bulmer, M. G. 1974. Linkage disequilibrium and genetic variability. Genet. Res. 23:281-289.
8. Bulmer, M. G. 1985. The mathematical theory of quantitative genetics. 2nd ed Oxford Univ. Press, Oxford, U.K.
9. Bulmer, M. G. 1989. Maintenance of genetic variability by mutation-selection balance: a child's guide through the jungle. Genome 31:761-767.
10. Bürger, R. 2000. The mathematical theory of selection, recombination, and mutation. Wiley, Chichester, U.K.
11. Charlesworth, B. 1990. Mutation-selection balance and the evolutionary advantage of sex and recombination. Genet. Res. 55:199-221.
12. Charlesworth, B. 1993. Directional selection and the evolution of sex and recombination. Genet. Res. 61:205-224.
13. Charlesworth, B. 2013. Why we are not dead one hundered times over. Evolution. doi:10.1111/evo.12195.
14. Charlesworth, B., and D. Charlesworth 1999. The genetic basis of inbreeding depression. Genet. Res. 74:329-40.
15. Charlesworth, D 2006. Evolution of plant breeding systems. Curr. Biol. 16:R726-R735.
16. Crow, J. F. 1970. Genetic loads and the cost of natural selection. Pp. 128-177 in K. Kojima, ed. Mathematical topics in population genetics. Springer-Verlag, Berlin.
17. Fisher, R. A. 1930. The genetical theory of natural selection. Clarendon Press, Oxford, U.K.
18. Gros, P.-A., H. Le Nagard, and O. Tenaillon 2009. The evolution of epistasis and its links with genetic robustness, complexity and drift in a phenotypic model of adaptation. Genetics 182:277-293.
19. Haldane, J. B. S. 1932. The causes of evolution. Longmans, Green, Lond.
20. Hartl, D. L., and C. H. Taubes 1998. Towards a theory of evolutionary adaptation. Genetica 103:525-33.
21. Hastings, W. K 1970. Monte Carlo sampling methods using Markov chains and their applications. Biometrika 57:97-109.
22. Johnson, T., and N. H. Barton 2005. Theoretical models of selection and mutation on quantitative traits. Phil. Trans. R. Soc. (Lond.) B 360:1411-1425.
23. Keightley, P. D., and S. P. Otto 2006. Interference among deleterious mutations favours sex and recombination in finite populations. Nature 443:89-92.
24. Kimura, M 1965. A stochastic model concerning the maintenance of genetic variability in quantitative characters. Proc. Natl. Acad. Sci. U. S. A. 54:731-736.
25. Kimura, M., and T. Maruyama 1966. The mutational load with epistatic gene interactions in fitness. Genetics 54:1337-1351.
26. Kondrashov, A. S. 1988. Deleterious mutations and the evolution of sexual reproduction. Nature 336:435-440.
27. Lande, R. 1976. The maintenance of genetic variability by mutation in a polygenic character with linked loci. Genet. Res. 26:221-235.
28. Lande, R. 1977. The influence of the mating system on the maintenance of genetic variability in polygenic characters. Genetics 86:485-498.
29. Lande, R. 1980. The genetic covariance between characters maintained by pleiotropic mutations. Genetics 94:203-215.
30. Lande, R., and D. W. Schemske 1985. The evolution of self-fertilization and inbreeding depression in plants. I. Genetic models. Evolution 39:24-40.
31. Lourenço, J., N. Galtier, and S. Glémin 2011. Complexity, pleiotropy and the fitness effect of mutations. Evolution 65:1559-1571.
32. Lynch, M., and J. B. Walsh 1998. Genetics and analysis of quantitative traits. Sinauer Associates, Sunderland, MA.
33. Martin, G., and T. Lenormand 2006. A general multivariate extension of Fisher's geometrical model and the distribution of mutation fitness effects across species. Evolution 60:893-907.
34. Martin, G., S. F. Elena, and T. Lenormand 2007. Distributions of epistasis in microbes fit predictions from a fitness landscape model. Nat. Genet. 39:555-560.
35. Orr, H. A. 1998. The population genetics of adaptation: the distribution of factors fixed during adaptive evolution. Evolution 52:935-949.
36. Orr, H. A. 2000. Adaptation and the cost of complexity. Evolution 54:13-20.
37. Otto, S. P. 2009. The evolutionary enigma of sex. Am. Nat. 174:S1-S14.
38. Otto, S. P., and D. B. Goldstein 1992. Recombination and the evolution of diploidy. Genetics 131:745-751.
39. Otto, S. P., and J. C. Marks 1996. Mating systems and the evolutionary transition between haploidy and diploidy. Biol. J. Linn. Soc. 57:197-218.
40. Poon, A., and S. P. Otto 2000. Compensating for our load of mutations: freezing the meltdown of small populations. Evolution 54:1467-1479.
41. Rowe, L., and D. Houle 1996. The lek paradox and the capture of genetic variance by condition dependent traits. Proc. R. Soc. (Lond.) B 263:1415-1421.
42. Sella, G 2009. An exact steady-state solution of Fisher's geometric model and other models. Theor. Popul. Biol. 75:30-34.
43. Sella, G., and A. E. Hirsh 2005. The application of statistical physics to evolutionary biology. Proc. Natl. Acad. Sci. U. S. A. 102:9541-9546.
44. Tenaillon, O., O. K. Silander, J.-P. Uzan, and L. Chao 2007. Quantifying organismal complexity using a population genetic approach. PLoS One 2:e217.
45. Turelli, M. 1984. Heritable genetic variation via mutation-selection balance: Lerch's zeta meets the abdominal bristle. Theor. Popul. Biol. 25:138-193.
46. Turelli, M. 1985. Effects of pleiotropy on predictions concerning mutation-selection balance for polygenic traits. Genetics 11:165-195.
47. Turelli, M., and N. H. Barton 1990. Dynamics of polygenic characters under selection. Theor. Popul. Biol. 38:1-57.
48. Turelli, M., and N. H. Barton 1994. Genetic and statistical analyses of strong selection on polygenic traits: what, me normal? Genetics 138:913-941.
49. Waxman, D., and J. R. Peck 1998. Pleiotropy and the preservation of perfection. Science 279:1210-1213.
50. Welch, J. J., and D. Waxman 2003. Modularity and the cost of complexity. Evolution 57:1723-1734.
51. Wilke, C. O., and C. Adami 2001. Interaction between directional epistasis and average mutational effects. Proc. Roy. Soc. (Lond.) B 268:1469-1474.
52. Wright, S 1935. Evolution in populations in approximate equilibrium. J. Genet. 30:257-266.
53. Zhang, X.-S, 2012. Fisher's geometrical model of fitness landscape and variance in fitness within a changing environment. Evolution 66:2350-2368.
54. Zhang, X.-S., and W. G. Hill 2003. Multivariate stabilizing selection and pleiotropy in the maintenance of quantitative genetic variation. Evolution 57:1761-1775.
55. Zhang, X.-S., and W. G. Hill 2005. Genetic variability under mutation selection balance. Trends Ecol. Evol. 20:468-470.