Comparing the efficacy of SNP filtering methods for identifying a single causal SNP in a known association region

Annals of Human Genetics

Volumn 78, Issue 1, 2014, Pages 50-61

  Spencer, Amy Victoria ^a   Cox, Angela ^a   Walters, Kevin ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Causal variants; Complex disease; Fine mapping; LD; Likelihood; p value; Single nucleotide polymorphism

Indexed keywords

ARTICLE; BREAST CANCER; COMPARATIVE STUDY; CONTROLLED STUDY; EFFECT SIZE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE MAPPING; GENETIC ASSOCIATION; GENOME; GENOTYPE; HAPLOTYPE; HUMAN; IMMUNE COMPLEX DISEASE; INHERITANCE; MELANOMA; PRIORITY JOURNAL; PROBABILITY; RECEIVER OPERATING CHARACTERISTIC; SAMPLE SIZE; SIMULATION; SINGLE NUCLEOTIDE POLYMORPHISM;

CAUSAL VARIANTS; COMPLEX DISEASE; FINE-MAPPING; LD; LIKELIHOOD; P-VALUE; SINGLE NUCLEOTIDE POLYMORPHISM;

COMPUTER SIMULATION; DATABASES, FACTUAL; GENE FREQUENCY; GENOME; GENOME-WIDE ASSOCIATION STUDY; GENOTYPING TECHNIQUES; HUMANS; LINKAGE DISEQUILIBRIUM; LOGISTIC MODELS; MODELS, GENETIC; ODDS RATIO; POLYMORPHISM, SINGLE NUCLEOTIDE; ROC CURVE; SAMPLE SIZE;

EID: 84890857555     PISSN: 00034800     EISSN: 14691809     Source Type: Journal    
DOI: 10.1111/ahg.12043     Document Type: Article

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