Balance deficit with opened or closed eyes reveals involvement of different structures of the central nervous system in multiple sclerosis

Multiple Sclerosis

Volumn 20, Issue 1, 2014, Pages 81-90

  Prosperini, Luca ^a   Petsas, Nikolaos ^a   Raz, Eytan ^a   Sbardella, Emilia ^a   Tona, Francesca ^a   Mancinelli, Chiara Rosa ^a   Pozzilli, Carlo ^a   Pantano, Patrizia ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Balance; center of pressure displacement; disability; lesions; magnetic resonance imaging; multiple sclerosis; posturography; vision

Indexed keywords

GADOLINIUM;

ADULT; ARTICLE; BALANCE IMPAIRMENT; BRAIN STEM; CEREBELLUM; CEREBROSPINAL FLUID; CERVICAL SPINAL CORD; CLINICAL ARTICLE; CONTRAST ENHANCEMENT; CONTROLLED STUDY; DISEASE DURATION; EXPANDED DISABILITY STATUS SCALE; EYE; FEMALE; HUMAN; MALE; MIDDLE CEREBELLAR PEDUNCLE; MULTIPLE SCLEROSIS; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; STABILOGRAPHY; WALKING SPEED; BRAIN; BRAIN ATROPHY; BRAIN DAMAGE; BRAIN REGION; CENTER OF PRESSURE DISPLACEMENT; CENTRAL NERVOUS SYSTEM; DISEASE ASSOCIATION; MAJOR CLINICAL STUDY; MID SAGITTAL CEREBELLUM AREA; NERVOUS SYSTEM PARAMETERS; SPINAL CORD; UPPER CERVICAL CORD CROSS SECTIONAL AREA; UROGRAPHY;

BALANCE; CENTER OF PRESSURE DISPLACEMENT; DISABILITY; LESIONS; MAGNETIC RESONANCE IMAGING; MULTIPLE SCLEROSIS; POSTUROGRAPHY; VISION;

ADULT; ATROPHY; BRAIN; FEMALE; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS; NEUROLOGIC EXAMINATION; POSTURAL BALANCE; SOMATOSENSORY DISORDERS; SPINAL CORD;

EID: 84890838984     PISSN: 13524585     EISSN: 14770970     Source Type: Journal    
DOI: 10.1177/1352458513490546     Document Type: Article

References (36)

1. Noseworthy JH, Lucchinetti C, Rodriguez M, et al. Multiple sclerosis. N Engl J Med. 2000 ; 343: 938-952
2. Cameron MH, Lord S. Postural control in multiple sclerosis: Implications for fall prevention. Curr Neurol Neurosci Rep. 2010 ; 10: 407-412
3. Peterson EW, Cho CC, Finlayson ML. Fear of falling and associated activity curtailment among middle aged and older adults with multiple sclerosis. Mult Scler. 2007 ; 13: 1168-1175
4. Jackson RT, Epstein CM, De l'Aune WR. Abnormalities in posturography and estimations of visual vertical and horizontal in multiple sclerosis. Am J Otol. 1995 ; 16: 88-93
5. Lanska DJ, Goetz CG. Romberg's sign: Development, adoption, and adaptation in the 19th century. Neurology. 2000 ; 55: 1201-1206
6. Mauritz KH, Dichgans J, Hufschmidt A. Quantitative analysis of stance in late cortical cerebellar atrophy of the anterior lobe and other forms of cerebellar ataxia. Brain. 1979 ; 102: 461-482
7. Visser JE, Carpenter MG, Van der Kooij H, et al. The clinical utility of posturography. Clin Neurophysiol. 2008 ; 119: 2424-2436
8. Cameron MH, Horak FB, Herndon RR, et al. Imbalance in multiple sclerosis: A result of slowed spinal somatosensory conduction. Somatosens Mot Res. 2008 ; 25: 113-122
9. Zackowski KM, Smith SA, Reich DS, et al. Sensorimotor dysfunction in multiple sclerosis and column-specific magnetization transfer-imaging abnormalities in the spinal cord. Brain. 2009 ; 132: 1200-1209
10. Prosperini L, Kouleridou A, Petsas N, et al. The relationship between infratentorial lesions, balance deficit and accidental falls in multiple sclerosis. J Neurol Sci. 2011 ; 304: 55-60
11. Prosperini L, Sbardella E, Raz E, et al. White and grey matter damage associated with balance deficit as detected by static posturography in multiple sclerosis. Radiology. 2013 ;:
12. Polman CH, Reingold SC, Edan G, et al. Diagnostic criteria for multiple sclerosis: 2005 revisions to the "McDonald Criteria.". Ann Neurol. 2005 ; 58: 840-846
13. Kurtzke JF. Rating neurological impairment in multiple sclerosis. An expanded disability status scale (EDSS). Neurology. 1983 ; 33: 1444-1452
14. Cutter GR, Baier ML, Rudick RA, et al. Development of a multiple sclerosis functional composite as a clinical trial outcome measure. Brain. 1999 ; 122: 871-882
15. Kieseier BC, Pozzilli C. Assessing walking disability in multiple sclerosis. Mult Scler. 2012 ; 18: 914-924
16. Cattaneo D, Jonsdottir J. Sensory impairments in quiet standing in subjects with multiple sclerosis. Mult Scler. 2008 ; 15: 1-9
17. Prosperini L, Fortuna D, Giannì C, et al. The diagnostic accuracy of static posturography in predicting accidental falls in people with multiple sclerosis. Neurorehabil Neural Repair. 2013 ; 27: 45-52
18. Horsfield MA, Sala S, Neema M, et al. Rapid semi-automatic segmentation of the spinal cord from magnetic resonance images: Application in multiple sclerosis. Neuroimage. 2010 ; 50: 446-455
19. Nopoulos PC, Ceilley JW, Gailis EA, et al. An MRI study of cerebellar vermis morphology in patients with schizophrenia: Evidence in support of the cognitive dysmetria concept. Biol Psychiatry. 1999 ; 46: 703-711
20. Aylward EH, Reiss A. Area and volume measurement of posterior fossa structures in MRI. J Psychiatr Res. 1991 ; 25: 159-168
21. Ouchi Y, Okada H, Yoshikawa E, et al. Brain activation during maintenance of standing postures in humans. Brain. 1999 ; 122: 329-338
22. Lin X, Tench CR, Turner B, et al. Spinal cord atrophy and disability in multiple sclerosis over four years: Application of a reproducible automated technique in monitoring disease progression in a cohort of the interferon beta-1a (Rebif) treatment trial. J Neurol Neurosurg Psychiatry. 2003 ; 74: 1090-1094
23. Giugni E, Pozzilli C, Bastianello S, et al. MRI measures and their relations with clinical disability in relapsing-remitting and secondary progressive multiple sclerosis. Mult Scler. 1997 ; 3: 221-225
24. Hickman SJ, Brierley CM, Silver NC, et al. Infratentorial hypointense lesion volume on T1-weighted magnetic resonance imaging correlates with disability in patients with chronic cerebellar ataxia due to multiple sclerosis. J Neurol Sci. 2001 ; 187: 35-39
25. Goldman SN. P-values, hypothesis tests and likelihood: Implications for epidemiology of a neglected historical debate. Am J Epidomiol. 1993 ; 137: 497-499
26. Ebner TJ, Palasar S. Cerebellum predicts the future motor state. Cerebellum. 2008 ; 7: 583-588
27. Anderson VM, Fisniku LK, Altmann DR, et al. MRI measures show significant cerebellar gray matter volume loss in multiple sclerosis and are associated with cerebellar dysfunction. Mult Scler. 2009 ; 15: 811-817
28. Anderson VM, Wheeler-Kingshott CAM, Abdel-Aziz K. A comprehensive assessment of cerebellar damage in multiple sclerosis using diffusion tractography and volumetric analysis. Mult Scler. 2011 ; 17: 1079-1087
29. Baloh RW, Jacobson KM, Beykirch K, et al. Static and dynamic posturography in patients with vestibular and cerebellar lesions. Arch Neurol. 1998 ; 55: 649-654
30. Timmann D, Brandauer B, Hermsdörfer J, et al. Lesion-symptom mapping of the human cerebellum. Cerebellum. 2008 ; 7: 602-606
31. Caeyenberghs K, Leemans A, Geurts M, et al. Brain-behaviour relationship in traumatic brain injury patients: DTI metrics are highly correlated with postural control. Hum Brain Mapp. 2010 ; 31: 992-1002
32. Nijeholt GJ, Van Walderveen MA, Castelijns JA, et al. Brain and spinal cord abnormalities in multiple sclerosis. Correlation between MRI parameters, clinical subtypes and symptoms. Brain. 1998 ; 121: 687-697
33. Stevenson VL, Leary SM, Losseff NA, et al. Spinal cord atrophy and disability in MS: A longitudinal study. Neurology. 1998 ; 51: 234-238
34. Oh J, Zackowski K, Chen M, Newsome S, et al. Multiparametric MRI correlates of sensorimotor function in the spinal cord in multiple sclerosis. Mult Scler. 2013 ; 19: 427-435
35. Fanchamps MHJ, Gensicke H, Kuhle J, et al. Screening for balance disorders in mildly affected multiple sclerosis patients. J Neurol. 2012 ; 259: 1413-1419
36. Kalron A, Dvir Z, Achiron A. Effect of a cognitive task on postural control in patients with a clinically isolated syndrome suggestive of multiple sclerosis. Eur J Phys Rehabil Med. 2011 ; 47: 579-586