Sensorimotor dysfunction in multiple sclerosis and column-specific magnetization transfer-imaging abnormalities in the spinal cord

Brain

Volumn 132, Issue 5, 2009, Pages 1200-1209

  Zackowski, Kathleen M ^a,b,c   Smith, Seth A ^a,b   Reich, Daniel S ^a   Gordon Lipkin, Eliza ^a   Chodkowski, Bettyann A ^b   Sambandan, Divya R ^b   Shteyman, Michael ^b   Bastian, Amy J ^a,b   Van Zijl, Peter C ^b   Calabresi, Peter A ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b KENNEDY KRIEGER INSTITUTE   (United States)

^c JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Corticospinal tract; Dorsal column medial lemniscal tract; Magnetic resonance imaging; Sensation; Strength

Indexed keywords

ADULT; ARTICLE; BALANCE IMPAIRMENT; BRAIN DAMAGE; CEREBROSPINAL FLUID; CERVICAL SPINAL CORD INJURY; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GRAY MATTER; HUMAN; MALE; MULTIPLE SCLEROSIS; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SENSORIMOTOR FUNCTION; SPINAL CORD; VIBRATION; WALKING DIFFICULTY; WHITE MATTER;

EID: 66549090046     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awp032     Document Type: Article

References (47)

1. Agosta F, Absinta M, Sormani MP, Ghezzi A, Bertolotto A, Montanari E, et al. In vivo assessment of cervical cord damage in MS patients: a longitudinal diffusion tensor MRI study. Brain 2007a; 130: 2211-2219 (Pubitemid 47236613)
2. Agosta F, Pagani E, Caputo D, Filippi M. Associations between cervical cord gray matter damage and disability in patients with multiple scle- rosis. Arch Neurol 2007b; 64: 1302-1305 (Pubitemid 47403085)
3. Arezzo JC, Schaumburg HH, Laudadio C. The Vibratron: a simple device for quantitative evaluation of tactile/vibratory sense. Neurology 1985; 35 (Suppl 1): 169.
4. Bakshi R, Thompson AJ, Rocca MA, Pelletier D, Dousset V, Barkhof F, et al. MRI in multiple sclerosis: current status and future prospects. Lancet Neurol 2008; 7: 615-625
5. Blamire A, Cader S, Lee M, Palace J, Matthews PM. Axonal damage in the spinal cord of multiple sclerosis patients detected by magnetic resonance spectroscopy. Magn Reson Med 2007; 58: 880-885 (Pubitemid 350074354)
6. Bohannon RW. Comfortable and maximum walking speed of adults aged 20-79 years: reference values and determinants. Age Ageing 1997a; 26: 15-19. (Pubitemid 27153910)
7. Bohannon RW. Reference values for extremity muscle strength obtained by hand-held dynamometry from adults aged 20 to 79 years. Arch Phys Med Rehabil 1997b; 78: 26-32. (Pubitemid 27034240)
8. Bot JCJ, Barkhof F. Spinal-cord MRI in multiple sclerosis: conventional and nonconventional MR techniques. Neuroimag Clin N Am 2009; 19: 81-99.
9. Bot JCJ, Barkhof F, Polman CH, Lycklama a Nieholt GJ, deGroot V, Bergers E, et al. Spinal cord abnormalities in recently diagnosed MS patients: added value of spinal MRI examination. Neurology 2004a; 62: 226-233 (Pubitemid 38167129)
10. Bot JCJ, Blezer ELA, Kamphorst W, et al. The spinal cord in multiple sclerosis: relationship of high-spatial-resolution quantitative MR imaging ?ndings to histopathologic results. Radiology 2004b; 233: 531-540 (Pubitemid 39423815)
11. Brex PA, Ciccarelli O, O'Riordan JI, Sailer M, Thompson AJ, Miller DH. A longitudinal study of abnormalities on MRI and disability from multiple sclerosis. New Engl J Med 2002; 346: 158-164 (Pubitemid 34438881)
12. Byrne CA, O'Keeffe DT, Donnelly AE, Lyons GM. Effect of walking speed changes on tibialis anterior EMG during healthy gait for FES envelope design in drop foot correction. J Electrom Kines 2007; 17: 605-616 (Pubitemid 47188047)
13. Cameron MH, Horak FB, Herndon RR, Bourdette D. Imbalance in mul-tiple sclerosis: a result of slowed spinal somatosensory conduction. Somato Mot Res 2008; 25: 113-122
14. Ciccarelli O, Wheeler-Kingshott CA, McLean MA, Cercignani M, Wimpey K, Miller DH, et al. Spinal cord spectroscopy and diffusion-based tractography to assess acute disability in multiple sclerosis. Brain 2007; 130: 2220-2231 (Pubitemid 47236629)
15. DeBoy CA, Zhang J, Dike S, Shats I, Jones M, Reich DS, et al. High resolution diffusion tensor imaging of axonal damage in focal in?ammatory and demyelinating lesions in rat spinal cord. Brain 2007; 130 (Pt 8): 2199-2210 (Pubitemid 47236617)
16. DeLuca GC, Ebers GC, Esiri M.M. Axonal loss in multiple sclerosis: a pathological survey of the corticospinal and sensory tracts. Brain 2004; 127: 1009-1018 (Pubitemid 38623038)
17. Evangelou N, DeLuca GC, Owens T, Esiri MM. Pathological study of spinal cord atrophy in multiple sclerosis suggests limited role of local lesions. Brain 2005; 128: 29-34. (Pubitemid 40070517)
18. Fatemi A, Smith SA, Dubey P, Zackowski KM, Bastian AJ, van Zijl PC, et al. Magnetization transfer MRI demonstrates spinal cord abnormalities in adrenomyeloneuropathy. Neurology 2005; 64: 1739-1745 (Pubitemid 40695808)
19. Fisniku LK, Chard DT, Jackson JS, Anderson VM, Altmann DR, Miszkiel KA, et al. Gray matter atrophy is related to long-term disability in multiple sclerosis. Ann Neurol 2008; 64: 247-254
20. Gardner AW. Dissipation of claudication pain after walking: implications for endurance training. Med Sci Sports Exer 1993; 25: 904-910 (Pubitemid 23228349)
21. Gauthier SA,Mandel M, Guttmann CRG, Glanz BI, Khoury SJ, Betensky RA. Predicting short-term disability in multiple sclerosis. Neurology 2007; 68: 2059-2065 (Pubitemid 46912123)
22. Geurts JJG, Barkhof F. Grey matter pathology in multiple sclerosis. Lancet 2008; 7: 841-851
23. Hobart J, Kalkers N, Barkhof F, Uitdehaag B, Polman C, Thompson A. Outcome measures for multiple sclerosis clinical trials: relative measurement precision of the Expanded Disability Status Scale and Multiple Sclerosis Functional Composite. Mult Scler 2004; 10: 41-46 (Pubitemid 38100525)
24. Horak F. Postural orientation and equilibrium: what do we need to know about neural control of balance to prevent falls? Age Ageing 2006; 35: ii7-11.
25. Ikuta F, Zimmerman HA. Distribution of plaques in seventy autopsy cases of multiple sclerosis in the United States. Neurology 1976; 8: 26-28
26. Jiang H, van Zijl PC, Kim J, Pearlson GD, Mori S. DtiStudio: resource program for diffusion tensor computation and ?ber bundle tracking. Comput Methods Programs Biomed 2006; 81: 106-116 (Pubitemid 43144442)
27. Kappos L, Moeri D, Radue EW, Schoetzau A, Schweikert K, Barkhof F, et al. Predictive value of gadolinium-enhanced magnetic resonance imaging for relapse rate and changes in disability or impairment in multiple sclerosis: a meta-analysis. Gadolinium MRI meta-analysis group. Lancet 1999; 353: 964-969 (Pubitemid 29132605)
28. Miller DH, Soon D, Fernando KT, MacManus DG, Barker GJ, Yousry TA, et al. MRI outcomies in placebo-controller trial of natalizumab in relapsing MS. Neurology 2007; 68: 1390-1401 (Pubitemid 46659091)
29. Naismith RT, Xu J, Tutlam NT, Snyder A, Benzinger T, Shimony J, et al. Disability in optic neuritis correlates with diffusion tensor-derived directional diffusivities. Neurology 2009; 72: 589-594
30. Ohgiya Y, Oka M, Hiwatashi A, Liu X, Kakimoto N, Westesson PL, et al. Diffusion tensor MR imaging of the cervical spinal cord in patients with multiple sclerosis. Eur Radiol 2007; 17: 2499-2504
31. Prieto TE, Myklebust JB, Hoffmann RG, Lovett EG, Myklebust BM. Measures of postural steadiness: differences between healthy young and elderly adults. IEEE Trans Biomed Eng 1996; 43: 956-966 (Pubitemid 26282069)
32. Reich DS, Smith SA, Zackowski KM, Gordon-Lipkin EM, Jones CK, Farrell JA, et al. Multiparametric magnetic resonance imaging analysis of the corticospinal tract in multiple sclerosis. Neuroimage 2007; 38: 271-279 (Pubitemid 47532736)
33. Reich DS, Zackowski KM, Gordon-Lipkin EM, Smith SA, Chodkowski BA, Cutter GR, et al. Corticospinal tract abnormalities are associated with weakness in multiple sclerosis. Am J Neuroradiol 2008; 29: 333-339
34. Rocca M, Hickman SJ, Bo L, Agosta F, Miller DH, Comi G, et al. Imaging spinal cord damage in multiple sclerosis. J Neuroimaging 2005; 15: 297-304. (Pubitemid 41395878)
35. Rovaris M, Comi G, Ladkani D, Wolinsky JS, Filippi M, European/Canadian Glatiramer Acetate Study Group. Short-term correlations between clinical and MRI-imaging ?ndings in relapsing-remitting multiple sclerosis. Am J Neurorad 2003; 24: 75-81. (Pubitemid 36110104)
36. Rudick R, Antel J, Confavreux C, Cutter G, Ellison G, Fischer J, et al. Recommendations from the National Multiple Sclerosis Society Clinical Outcomes Assessment Task Force. Ann Neurol 1997; 42: 379-382 (Pubitemid 127744543)
37. Schmierer K, Scaravilli F, Altmann DR, Barker GJ, Miller DH. Magnetization tranfer ratio and myelin in postmortem multiple sclerosis brain. Ann Neurol 2004; 56: 407-415 (Pubitemid 39166560)
38. Schmierer K, Tozer DJ, Scaravilli F, Altmann DR, Barker GJ, Tofts PS, et al. Quantitative magnetization transfer imaging in postmortem multiple sclerosis brain. J Magn Res Imag 2007; 26: 41-51. (Pubitemid 47235229)
39. Schreiber K, Sorenson PS, Koch-Henriksen N, Wagner A, Blinkenberg M, Svarer C, et al. Correlations of brain MRI parameters to disability in multiple sclerosis. Acta Neurol Scan 2001; 104: 24-30. (Pubitemid 32588396)
40. Schwid SR, Goodman AD, Mattson DH, Mihai C, Donohoe KM, Petrie MD, et al. The measurement of ambulatory impairment in multiple sclerosis. Neurology 1997; 49: 1419-1424 (Pubitemid 27495653)
41. Sled JG, Pike GB. Quantitative imaging of magnetization transfer exchange and relaxation properties in vivo using MRI. Magn Res Med 2001; 46: 923-931 (Pubitemid 33019916)
42. Smith SA, Golay X, Fatemi A, Jones CK, Raymond GV, Moser HW, et al. Magnetization transfer weighted imaging in the upper cervical spinal cord using cerebrospinal ?uid as intersubject normalization reference (MTCSF imaging). Magn Res Med 2005; 54: 201-206 (Pubitemid 40898414)
43. Smith SA, Golay X, Fatemi A, Mahmood A, Raymond GV, Moser HW, et al. Quantitative magnetization transfer characteristics of the human cervical spinal cord in vivo: application to adrenomyeloneuropathy. Magn Res Med 2009; 61: 22-27
44. van Buchem RA, McGowan JC, Grossman RI. Magnetization transfer histogram methodology: its clinical and neuropsychological correlates. Neurology 1999; 53 (Suppl 3): S23-8.
45. van Walderveen MAA, Barkhof F, Hommes OR, Polman CH, Tobi H, Frequin ST, et al. Correlating MRI and clinical disease activity in multiple sclerosis: Relevance of hypointense lesions on short-TR/short-TE (T1-weighted) spin-echo images. Neurology 1995; 45: 1684-1690
46. Wu GF, Schwartz ED, Lei T, Souza A, Mishra S, Jacobs DA, et al. Relation of vision to global and regional brain MRI in multiple sclerosis. Neurology 2007; 69: 2128-2135 (Pubitemid 350294693)
47. Zivadinov R, Banas AC, Yella V, Abdelrahman N, Weinstock-Guttman B, Dwyer MG. Comparison of three different methods for measurement of cervical cord atrophy in multiple sclerosis. Am J Neurorad 2008; 29: 319-325