메뉴 건너뛰기




Volumn 15, Issue 7, 2009, Pages 811-817

MRI measures show significant cerebellar gray matter volume loss in multiple sclerosis and are associated with cerebellar dysfunction

Author keywords

Atrophy; Cerebellum; Gray matter; Multiple sclerosis; Region of interest

Indexed keywords

ADULT; ARTICLE; BRAIN ATROPHY; BRAIN SIZE; CEREBELLUM INJURY; CEREBROSPINAL FLUID; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; FEMALE; GRAY MATTER; HUMAN; IMAGE ANALYSIS; IMAGE PROCESSING; MAJOR CLINICAL STUDY; MALE; MULTIPLE SCLEROSIS; NUCLEAR MAGNETIC RESONANCE IMAGING; WHITE MATTER;

EID: 67649365980     PISSN: 13524585     EISSN: None     Source Type: Journal    
DOI: 10.1177/1352458508101934     Document Type: Article
Times cited : (71)

References (46)
  • 2
    • 0034842126 scopus 로고    scopus 로고
    • Transected neurites, apoptotic neurons, and reduced inflammation in cortical multiple sclerosis lesions
    • Peterson, JW, Bo, L, Mork, S, Chang, A, Trapp, BD. Transected neurites, apoptotic neurons, and reduced inflammation in cortical multiple sclerosis lesions. Ann Neurol 2001; 50: 389-400.
    • (2001) Ann Neurol , vol.50 , pp. 389-400
    • Peterson, J.W.1    Bo, L.2    Mork, S.3    Chang, A.4    Trapp, B.D.5
  • 3
    • 27644552194 scopus 로고    scopus 로고
    • Cortical demyelination and diffuse white matter injury in multiple sclerosis
    • Kutzelnigg, A, Lucchinetti, CF, Stadelmann, C, et al. Cortical demyelination and diffuse white matter injury in multiple sclerosis. Brain 2005; 128: 2705-2712.
    • (2005) Brain , vol.128 , pp. 2705-2712
    • Kutzelnigg, A.1    Lucchinetti, C.F.2    Stadelmann, C.3
  • 4
    • 20744442122 scopus 로고    scopus 로고
    • Intracortical lesions in multiple sclerosis: Improved detection with 3D double inversionrecovery MR imaging
    • Geurts, JJ, Pouwels, PJ, Uitdehaag, BM, Polman, CH, Barkhof, F, Castelijns, JA. Intracortical lesions in multiple sclerosis: Improved detection with 3D double inversionrecovery MR imaging. Radiology 2005; 236: 254-260.
    • (2005) Radiology , vol.236 , pp. 254-260
    • Geurts, J.J.1    Pouwels, P.J.2    Uitdehaag, B.M.3    Polman, C.H.4    Barkhof, F.5    Castelijns, J.A.6
  • 5
    • 33646799546 scopus 로고    scopus 로고
    • In vivo detection of cortical plaques by MR imaging in patients with multiple sclerosis
    • Bagnato, F, Butman, JA, Gupta, S, et al. In vivo detection of cortical plaques by MR imaging in patients with multiple sclerosis. AJNR Am J Neuroradiol 2006; 27: 2161-2167.
    • (2006) AJNR Am J Neuroradiol , vol.27 , pp. 2161-2167
    • Bagnato, F.1    Butman, J.A.2    Gupta, S.3
  • 6
    • 35349014120 scopus 로고    scopus 로고
    • Improved identification of intracortical lesions in multiple sclerosis with phase-sensitive inversion recovery in combination with fast double inversion recovery MR imaging
    • Nelson, F, Poonawalla, AH, Hou, P, Huang, F, Wolinsky, JS, Narayana, PA. Improved identification of intracortical lesions in multiple sclerosis with phase-sensitive inversion recovery in combination with fast double inversion recovery MR imaging. AJNR Am J Neuroradiol 2007; 28: 1645-1649.
    • (2007) AJNR Am J Neuroradiol , vol.28 , pp. 1645-1649
    • Nelson, F.1    Poonawalla, A.H.2    Hou, P.3    Huang, F.4    Wolinsky, J.S.5    Narayana, P.A.6
  • 7
    • 35348874326 scopus 로고    scopus 로고
    • Detection of cortical inflammatory lesions by double inversion recovery magnetic resonance imaging in patients with multiple sclerosis
    • Calabrese, M, De Stefano, N, Atzori, M, et al. Detection of cortical inflammatory lesions by double inversion recovery magnetic resonance imaging in patients with multiple sclerosis. Arch Neurol 2007; 64: 1416-1422.
    • (2007) Arch Neurol , vol.64 , pp. 1416-1422
    • Calabrese, M.1    De Stefano, N.2    Atzori, M.3
  • 8
    • 20444486522 scopus 로고    scopus 로고
    • Grey and white matter volume changes in early primary progressive multiple sclerosis: A longitudinal study
    • Sastre-Garriga, J, Ingle, GT, Chard, DT, et al. Grey and white matter volume changes in early primary progressive multiple sclerosis: A longitudinal study. Brain 2005; 128: 1454-1460.
    • (2005) Brain , vol.128 , pp. 1454-1460
    • Sastre-Garriga, J.1    Ingle, G.T.2    Chard, D.T.3
  • 9
    • 15244357270 scopus 로고    scopus 로고
    • Gray and white matter volume changes in early RRMS: A 2-year longitudinal study
    • Tiberio, M, Chard, DT, Altmann, DR, et al. Gray and white matter volume changes in early RRMS: A 2-year longitudinal study. Neurology 2005; 64: 1001-1007.
    • (2005) Neurology , vol.64 , pp. 1001-1007
    • Tiberio, M.1    Chard, D.T.2    Altmann, D.R.3
  • 10
    • 26444612710 scopus 로고    scopus 로고
    • Evidence for progressive gray matter loss in patients with relapsing-remitting MS
    • Valsasina, P, Benedetti, B, Rovaris, M, Sormani, MP, Comi, G, Filippi, M. Evidence for progressive gray matter loss in patients with relapsing-remitting MS. Neurology 2005; 65: 1126-1128.
    • (2005) Neurology , vol.65 , pp. 1126-1128
    • Valsasina, P.1    Benedetti, B.2    Rovaris, M.3    Sormani, M.P.4    Comi, G.5    Filippi, M.6
  • 11
    • 34249006493 scopus 로고    scopus 로고
    • Interferon beta-1a slows progression of brain atrophy in relapsingremitting multiple sclerosis predominantly by reducing gray matter atrophy
    • Zivadinov, R, Locatelli, L, Cookfair, D, et al. Interferon beta-1a slows progression of brain atrophy in relapsingremitting multiple sclerosis predominantly by reducing gray matter atrophy. Mult Scler 2007; 13: 490-501.
    • (2007) Mult Scler , vol.13 , pp. 490-501
    • Zivadinov, R.1    Locatelli, L.2    Cookfair, D.3
  • 12
    • 2442423348 scopus 로고    scopus 로고
    • Early development of multiple sclerosis is associated with progressive grey matter atrophy in patients presenting with clinically isolated syndromes
    • Dalton, CM, Chard, DT, Davies, GR, et al. Early development of multiple sclerosis is associated with progressive grey matter atrophy in patients presenting with clinically isolated syndromes. Brain 2004; 127: 1101-1107.
    • (2004) Brain , vol.127 , pp. 1101-1107
    • Dalton, C.M.1    Chard, D.T.2    Davies, G.R.3
  • 13
    • 54849431592 scopus 로고    scopus 로고
    • Gray matter atrophy is related to long-term disability in multiple sclerosis
    • Fisniku, LK, Chard, DT, Jackson, JS, et al. Gray matter atrophy is related to long-term disability in multiple sclerosis. Ann Neurol 2008; 64: 247-254.
    • (2008) Ann Neurol , vol.64 , pp. 247-254
    • Fisniku, L.K.1    Chard, D.T.2    Jackson, J.S.3
  • 14
    • 20444385866 scopus 로고    scopus 로고
    • The relationship between whole brain volume and disability in multiple sclerosis: A comparison of normalized gray vs. white matter with misclassification correction
    • Sanfilipo, MP, Benedict, RH, Sharma, J, Weinstock-Guttman, B, Bakshi, R. The relationship between whole brain volume and disability in multiple sclerosis: A comparison of normalized gray vs. white matter with misclassification correction. Neuroimage 2005; 26: 1068-1077.
    • (2005) Neuroimage , vol.26 , pp. 1068-1077
    • Sanfilipo, M.P.1    Benedict, R.H.2    Sharma, J.3    Weinstock-Guttman, B.4    Bakshi, R.5
  • 15
    • 51649084084 scopus 로고    scopus 로고
    • A magnetic resonance imaging voxel-based morphometry study of regional gray matter atrophy in patients with benign multiple sclerosis
    • Mesaros, S, Rovaris, M, Pagani, E, et al. A magnetic resonance imaging voxel-based morphometry study of regional gray matter atrophy in patients with benign multiple sclerosis. Arch Neurol 2008; 65: 1223-1230.
    • (2008) Arch Neurol , vol.65 , pp. 1223-1230
    • Mesaros, S.1    Rovaris, M.2    Pagani, E.3
  • 16
    • 31044434378 scopus 로고    scopus 로고
    • Grey matter loss in relapsing-remitting multiple sclerosis: A voxelbased morphometry study
    • Prinster, A, Quarantelli, M, Orefice, G, et al. Grey matter loss in relapsing-remitting multiple sclerosis: A voxelbased morphometry study. Neuroimage 2006; 29: 859-867.
    • (2006) Neuroimage , vol.29 , pp. 859-867
    • Prinster, A.1    Quarantelli, M.2    Orefice, G.3
  • 17
    • 33645731532 scopus 로고    scopus 로고
    • Evidence for a direct association between cortical atrophy and cognitive impairment in relapsing-remitting MS
    • Morgen, K, Sammer, G, Courtney, SM, et al. Evidence for a direct association between cortical atrophy and cognitive impairment in relapsing-remitting MS. Neuroimage 2006; 30: 891-898.
    • (2006) Neuroimage , vol.30 , pp. 891-898
    • Morgen, K.1    Sammer, G.2    Courtney, S.M.3
  • 19
    • 33747187744 scopus 로고    scopus 로고
    • Regional gray matter atrophy in early primary progressive multiple sclerosis: A voxelbased morphometry study
    • Sepulcre, J, Sastre-Garriga, J, Cercignani, M, Ingle, GT, Miller, DH, Thompson, AJ. Regional gray matter atrophy in early primary progressive multiple sclerosis: A voxelbased morphometry study. Arch Neurol 2006; 63: 1175-1180.
    • (2006) Arch Neurol , vol.63 , pp. 1175-1180
    • Sepulcre, J.1    Sastre-Garriga, J.2    Cercignani, M.3    Ingle, G.T.4    Miller, D.H.5    Thompson, A.J.6
  • 21
    • 0344837704 scopus 로고    scopus 로고
    • Selective caudate atrophy in multiple sclerosis: A 3D MRI parcellation study
    • Bermel, RA, Innus, MD, Tjoa, CW, Bakshi, R. Selective caudate atrophy in multiple sclerosis: A 3D MRI parcellation study. Neuroreport 2003; 14: 335-339.
    • (2003) Neuroreport , vol.14 , pp. 335-339
    • Bermel, R.A.1    Innus, M.D.2    Tjoa, C.W.3    Bakshi, R.4
  • 24
    • 33847227721 scopus 로고    scopus 로고
    • Widespread demyelination in the cerebellar cortex in multiple sclerosis
    • Kutzelnigg, A, Faber-Rod, JC, Bauer, J, et al. Widespread demyelination in the cerebellar cortex in multiple sclerosis. Brain Pathol 2007; 17: 38-44.
    • (2007) Brain Pathol , vol.17 , pp. 38-44
    • Kutzelnigg, A.1    Faber-Rod, J.C.2    Bauer, J.3
  • 25
    • 45849104594 scopus 로고    scopus 로고
    • A voxel-based morphometry study of grey matter loss in MS patients with different clinical phenotypes
    • Ceccarelli, A, Rocca, MA, Pagani, E, et al. A voxel-based morphometry study of grey matter loss in MS patients with different clinical phenotypes. Neuroimage 2008; 42: 315-322.
    • (2008) Neuroimage , vol.42 , pp. 315-322
    • Ceccarelli, A.1    Rocca, M.A.2    Pagani, E.3
  • 26
    • 0034565136 scopus 로고    scopus 로고
    • A prospective study on the prognosis of multiple sclerosis
    • Amato, MP, Ponziani, G. A prospective study on the prognosis of multiple sclerosis. Neurol Sci 2000; 21: S831-S838.
    • (2000) Neurol Sci , vol.21
    • Amato, M.P.1    Ponziani, G.2
  • 27
    • 0020686503 scopus 로고
    • New diagnostic criteria for multiple sclerosis: Guidelines for research protocols
    • Poser, CM, Paty, DW, Scheinberg, L, et al. New diagnostic criteria for multiple sclerosis: Guidelines for research protocols. Ann Neurol 1983; 13: 227-231.
    • (1983) Ann Neurol , vol.13 , pp. 227-231
    • Poser, C.M.1    Paty, D.W.2    Scheinberg, L.3
  • 28
    • 0029913882 scopus 로고    scopus 로고
    • Defining the clinical course of multiple sclerosis: Results of an international survey
    • National Multiple Sclerosis Society (USA) Advisory Committee on Clinical Trials of New Agents in Multiple Sclerosis
    • Lublin, FD, Reingold, SC. Defining the clinical course of multiple sclerosis: Results of an international survey. National Multiple Sclerosis Society (USA) Advisory Committee on Clinical Trials of New Agents in Multiple Sclerosis. Neurology 1996; 46: 907-911.
    • (1996) Neurology , vol.46 , pp. 907-911
    • Lublin, F.D.1    Reingold, S.C.2
  • 30
    • 0027080195 scopus 로고
    • DispImage: A display and analysis tool for medical images
    • Plummer, DL. DispImage: A display and analysis tool for medical images. Revista di Neuroradiologia 1992; 5: 489-495.
    • (1992) Revista Di Neuroradiologia , vol.5 , pp. 489-495
    • Plummer, D.L.1
  • 31
    • 0021035886 scopus 로고
    • Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS)
    • Kurtzke, JF. Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS). Neurology 1983; 33: 1444-1452.
    • (1983) Neurology , vol.33 , pp. 1444-1452
    • Kurtzke, J.F.1
  • 32
    • 0032919071 scopus 로고    scopus 로고
    • Development of a multiple sclerosis functional composite as a clinical trial outcome measure
    • Cutter, GR, Baier, ML, Rudick, RA, et al. Development of a multiple sclerosis functional composite as a clinical trial outcome measure. Brain 1999; 122: 871-882.
    • (1999) Brain , vol.122 , pp. 871-882
    • Cutter, G.R.1    Baier, M.L.2    Rudick, R.A.3
  • 34
    • 0032955860 scopus 로고    scopus 로고
    • Infratentorial atrophy on magnetic resonance imaging and disability in multiple sclerosis
    • Edwards, SG, Gong, QY, Liu, C, et al. Infratentorial atrophy on magnetic resonance imaging and disability in multiple sclerosis. Brain 1999; 122: 291-301.
    • (1999) Brain , vol.122 , pp. 291-301
    • Edwards, S.G.1    Gong, Q.Y.2    Liu, C.3
  • 35
    • 0032934804 scopus 로고    scopus 로고
    • Three dimensional MRI estimates of brain and spinal cord atrophy in multiple sclerosis
    • Liu, C, Edwards, S, Gong, Q, Roberts, N, Blumhardt, LD. Three dimensional MRI estimates of brain and spinal cord atrophy in multiple sclerosis. J Neurol Neurosurg Psychiatry 1999; 66: 323-330.
    • (1999) J Neurol Neurosurg Psychiatry , vol.66 , pp. 323-330
    • Liu, C.1    Edwards, S.2    Gong, Q.3    Roberts, N.4    Blumhardt, L.D.5
  • 36
    • 0032581188 scopus 로고    scopus 로고
    • Quantitative volumetric analysis of brain magnetic resonance imaging from patients with multiple sclerosis
    • Filippi, M, Mastronardo, G, Rocca, MA, Pereira, C, Comi, G. Quantitative volumetric analysis of brain magnetic resonance imaging from patients with multiple sclerosis. J Neurol Sci 1998; 158: 148-153.
    • (1998) J Neurol Sci , vol.158 , pp. 148-153
    • Filippi, M.1    Mastronardo, G.2    Rocca, M.A.3    Pereira, C.4    Comi, G.5
  • 37
    • 0344873094 scopus 로고    scopus 로고
    • The relationship of brain and cervical cord volume to disability in clinical subtypes of multiple sclerosis: A threedimensional MRI study
    • Lin, X, Blumhardt, LD, Constantinescu, CS. The relationship of brain and cervical cord volume to disability in clinical subtypes of multiple sclerosis: A threedimensional MRI study. Acta Neurol Scand 2003; 108: 401-406.
    • (2003) Acta Neurol Scand , vol.108 , pp. 401-406
    • Lin, X.1    Blumhardt, L.D.2    Constantinescu, C.S.3
  • 38
    • 2342593231 scopus 로고    scopus 로고
    • Differential cerebellar activation on functional magnetic resonance imaging during working memory performance in persons with multiple sclerosis
    • Li, Y, Chiaravalloti, ND, Hillary, FG, et al. Differential cerebellar activation on functional magnetic resonance imaging during working memory performance in persons with multiple sclerosis. Arch Phys Med Rehabil 2004; 85: 635-639.
    • (2004) Arch Phys Med Rehabil , vol.85 , pp. 635-639
    • Li, Y.1    Chiaravalloti, N.D.2    Hillary, F.G.3
  • 39
    • 58149337565 scopus 로고    scopus 로고
    • Structural and functional MRI correlates of Stroop control in benign MS
    • Rocca, MA, Valsasina, P, Ceccarelli, A, et al. Structural and functional MRI correlates of Stroop control in benign MS. Hum Brain Mapp 2009; 30: 276-290.
    • (2009) Hum Brain Mapp , vol.30 , pp. 276-290
    • Rocca, M.A.1    Valsasina, P.2    Ceccarelli, A.3
  • 40
    • 0029565567 scopus 로고
    • Persistent functional deficit in multiple sclerosis and autosomal dominant cerebellar ataxia is associated with axon loss
    • Davie, CA, Barker, GJ, Webb, S, et al. Persistent functional deficit in multiple sclerosis and autosomal dominant cerebellar ataxia is associated with axon loss. Brain 1995; 118: 1583-1592.
    • (1995) Brain , vol.118 , pp. 1583-1592
    • Davie, C.A.1    Barker, G.J.2    Webb, S.3
  • 41
    • 33644964899 scopus 로고    scopus 로고
    • Cortical atrophy in the cerebellar variant of multiple system atrophy: A voxel-based morphometry study
    • Brenneis, C, Boesch, SM, Egger, KE, et al. Cortical atrophy in the cerebellar variant of multiple system atrophy: A voxel-based morphometry study. Mov Disord 2006; 21: 159-165.
    • (2006) Mov Disord , vol.21 , pp. 159-165
    • Brenneis, C.1    Boesch, S.M.2    Egger, K.E.3
  • 42
    • 60049099598 scopus 로고    scopus 로고
    • Brain structural damage in spinocerebellar ataxia type 1: A VBM study
    • Ginestroni, A, Della, NR, Tessa, C, et al. Brain structural damage in spinocerebellar ataxia type 1: A VBM study. J Neurol 2008; 255: 1153-1158.
    • (2008) J Neurol , vol.255 , pp. 1153-1158
    • Ginestroni, A.1    Della, N.R.2    Tessa, C.3
  • 43
    • 33749515747 scopus 로고    scopus 로고
    • Dissociation of grey and white matter reduction in spinocerebellar ataxia type 3 and 6: A voxel-based morphometry study
    • Lukas, C, Schols, L, Bellenberg, B, et al. Dissociation of grey and white matter reduction in spinocerebellar ataxia type 3 and 6: A voxel-based morphometry study. Neurosci Lett 2006; 408: 230-235.
    • (2006) Neurosci Lett , vol.408 , pp. 230-235
    • Lukas, C.1    Schols, L.2    Bellenberg, B.3
  • 44
    • 60249099507 scopus 로고    scopus 로고
    • Regional variations in the extent and pattern of grey matter demyelination in Multiple Sclerosis: A comparison between the cerebral cortex, cerebellar cortex, deep grey matter nuclei and the spinal cord
    • Gilmore, CP, Donaldson, I, Bo, L, Owens, T, Lowe, JS, Evangelou, N. Regional variations in the extent and pattern of grey matter demyelination in Multiple Sclerosis: A comparison between the cerebral cortex, cerebellar cortex, deep grey matter nuclei and the spinal cord. J Neurol Neurosurg Psychiatry 2009; 80: 182-187.
    • (2009) J Neurol Neurosurg Psychiatry , vol.80 , pp. 182-187
    • Gilmore, C.P.1    Donaldson, I.2    Bo, L.3    Owens, T.4    Lowe, J.S.5    Evangelou, N.6
  • 45
    • 21344460544 scopus 로고    scopus 로고
    • MRI T2 hypointensity of the dentate nucleus is related to ambulatory impairment in multiple sclerosis
    • Tjoa, CW, Benedict, RH, Weinstock-Guttman, B, Fabiano, AJ, Bakshi, R. MRI T2 hypointensity of the dentate nucleus is related to ambulatory impairment in multiple sclerosis. J Neurol Sci 2005; 234: 17-24.
    • (2005) J Neurol Sci , vol.234 , pp. 17-24
    • Tjoa, C.W.1    Benedict, R.H.2    Weinstock-Guttman, B.3    Fabiano, A.J.4    Bakshi, R.5
  • 46
    • 39749200152 scopus 로고    scopus 로고
    • Disability and T2 MRI lesions: A 20-year follow-up of patients with relapse onset of multiple sclerosis
    • Fisniku, LK, Brex, PA, Altmann, DR, et al. Disability and T2 MRI lesions: A 20-year follow-up of patients with relapse onset of multiple sclerosis. Brain 2008; 131: 808-817.
    • (2008) Brain , vol.131 , pp. 808-817
    • Fisniku, L.K.1    Brex, P.A.2    Altmann, D.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.