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Volumn 120, Issue , 2014, Pages 927-943

The neurology of folic acid deficiency

Author keywords

Aging; Dementia; Depression; Folic acid; Megaloblastic anemia; Methylation; Neuropathy

Indexed keywords

FOLIC ACID;

EID: 84890837249     PISSN: 00729752     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-7020-4087-0.00061-9     Document Type: Chapter
Times cited : (112)

References (146)
  • 1
    • 33749674369 scopus 로고
    • Neurologic aspects of primary anaemia
    • Ahrens R.S. Neurologic aspects of primary anaemia. Arch Neurol Psychiatry 1932, 28:92-109.
    • (1932) Arch Neurol Psychiatry , vol.28 , pp. 92-109
    • Ahrens, R.S.1
  • 2
    • 0003538141 scopus 로고    scopus 로고
    • Marcel Dekker, New York, L.B. Bailey (Ed.)
    • Folate in Health and Disease 1995, Marcel Dekker, New York. L.B. Bailey (Ed.).
    • (1995) Folate in Health and Disease
  • 3
    • 0003538141 scopus 로고    scopus 로고
    • CRC Press, Boca Raton, L.B. Bailey (Ed.)
    • Folate in Health and Disease 2010, CRC Press, Boca Raton. 2nd edn. L.B. Bailey (Ed.).
    • (2010) Folate in Health and Disease
  • 4
    • 84884836751 scopus 로고    scopus 로고
    • Folic acid fortification: neural tube defect risk reduction - a global perspective
    • CRC Press, Boca Raton, L.B. Bailey (Ed.)
    • Berry R.J., Mulinare J., Hamner H.C. Folic acid fortification: neural tube defect risk reduction - a global perspective. Folate in Health and Disease 2010, 179-204. CRC Press, Boca Raton. L.B. Bailey (Ed.).
    • (2010) Folate in Health and Disease , pp. 179-204
    • Berry, R.J.1    Mulinare, J.2    Hamner, H.C.3
  • 5
    • 0038314480 scopus 로고    scopus 로고
    • Folate, vitamin B12, homocysteine, and the MTHFR 677C→T polymorphism in anxiety and depression: the Hordaland homocysteine study
    • Bjelland I., Tell G.S., Vollset S.E., et al. Folate, vitamin B12, homocysteine, and the MTHFR 677C→T polymorphism in anxiety and depression: the Hordaland homocysteine study. Arch Gen Psychiatry 2003, 60:618-625.
    • (2003) Arch Gen Psychiatry , vol.60 , pp. 618-625
    • Bjelland, I.1    Tell, G.S.2    Vollset, S.E.3
  • 6
    • 33747588534 scopus 로고    scopus 로고
    • Neural tube defects and folate: case far from closed
    • Blom H.J., Shaw G.M., den Heijer T., et al. Neural tube defects and folate: case far from closed. Nat Rev Neurosci 2006, 7:724-731.
    • (2006) Nat Rev Neurosci , vol.7 , pp. 724-731
    • Blom, H.J.1    Shaw, G.M.2    den Heijer, T.3
  • 8
    • 0017566043 scopus 로고
    • Folate-responsive neurological and mental disorders: report of 16 cases
    • Botez M.I., Fontaine F., Botez T., et al. Folate-responsive neurological and mental disorders: report of 16 cases. Eur Neurol 1977, 16:230-246.
    • (1977) Eur Neurol , vol.16 , pp. 230-246
    • Botez, M.I.1    Fontaine, F.2    Botez, T.3
  • 10
    • 0002286288 scopus 로고
    • Neuropsychological correlates of folic acid deficiency: facts and hypotheses
    • Raven Press, New York, M.I. Botez, E.H. Reynolds (Eds.)
    • Botez M.I., Botez T., Léveillé J., et al. Neuropsychological correlates of folic acid deficiency: facts and hypotheses. Folic Acid in Neurology, Psychiatry and Internal Medicine 1979, 435-461. Raven Press, New York. M.I. Botez, E.H. Reynolds (Eds.).
    • (1979) Folic Acid in Neurology, Psychiatry and Internal Medicine , pp. 435-461
    • Botez, M.I.1    Botez, T.2    Léveillé, J.3
  • 11
    • 84855752350 scopus 로고    scopus 로고
    • Folate in neurological disease: basic mechanisms
    • CRC Press, Boca Raton, L.B. Bailey (Ed.)
    • Bottiglieri T., Reynolds E. Folate in neurological disease: basic mechanisms. Folate in Health and Disease 2010, 355-380. CRC Press, Boca Raton. L.B. Bailey (Ed.).
    • (2010) Folate in Health and Disease , pp. 355-380
    • Bottiglieri, T.1    Reynolds, E.2
  • 12
    • 0025606597 scopus 로고
    • Cerebrospinal fluid S-adenosylmethionine in depression and dementia: effects of treatment with parenteral and oral S-adenosylmethionine
    • Bottiglieri T., Godfrey P., Flynn T., et al. Cerebrospinal fluid S-adenosylmethionine in depression and dementia: effects of treatment with parenteral and oral S-adenosylmethionine. J Neurol Neurosurg Psychiatry 1990, 53:1096-1098.
    • (1990) J Neurol Neurosurg Psychiatry , vol.53 , pp. 1096-1098
    • Bottiglieri, T.1    Godfrey, P.2    Flynn, T.3
  • 13
    • 0027049833 scopus 로고
    • Folate deficiency, biopterin and monoamine metabolism on depression
    • Bottiglieri T., Hyland K., Laundy M., et al. Folate deficiency, biopterin and monoamine metabolism on depression. Psychol Med 1992, 22:871-876.
    • (1992) Psychol Med , vol.22 , pp. 871-876
    • Bottiglieri, T.1    Hyland, K.2    Laundy, M.3
  • 14
    • 0028102526 scopus 로고
    • The clinical potential of ademethionine (S-adenosylmethionine) in neurological disorders
    • Bottiglieri T., Hyland K., Reynolds E.H. The clinical potential of ademethionine (S-adenosylmethionine) in neurological disorders. Drugs 1994, 48:1137-1152.
    • (1994) Drugs , vol.48 , pp. 1137-1152
    • Bottiglieri, T.1    Hyland, K.2    Reynolds, E.H.3
  • 17
    • 0033925828 scopus 로고    scopus 로고
    • Homocysteine, folate, methylation and monoamine metabolism in depression
    • Bottiglieri T., Laundy M., Crellin R., et al. Homocysteine, folate, methylation and monoamine metabolism in depression. J Neurol Neurosurg Psychiatry 2000, 69:228-232.
    • (2000) J Neurol Neurosurg Psychiatry , vol.69 , pp. 228-232
    • Bottiglieri, T.1    Laundy, M.2    Crellin, R.3
  • 18
    • 73349134990 scopus 로고    scopus 로고
    • Congenital null mutations of the FOLR1 gene: a progressive neurologic disease and its treatment
    • Cario H., Bode H., Debaton K.M., et al. Congenital null mutations of the FOLR1 gene: a progressive neurologic disease and its treatment. Neurology 2009, 73:2127-2129.
    • (2009) Neurology , vol.73 , pp. 2127-2129
    • Cario, H.1    Bode, H.2    Debaton, K.M.3
  • 19
    • 0004285329 scopus 로고    scopus 로고
    • Cambridge University Press, Cambridge, R. Carmel, D.W. Jacobsen (Eds.)
    • Homocysteine in Health and Disease 2001, Cambridge University Press, Cambridge. R. Carmel, D.W. Jacobsen (Eds.).
    • (2001) Homocysteine in Health and Disease
  • 20
    • 0014788288 scopus 로고
    • Associations of subnormal folate and vitaminB12 values and effects of replacement therapy
    • Carney M.W.P., Sheffield B.F. Associations of subnormal folate and vitaminB12 values and effects of replacement therapy. J Nerv Ment Dis 1970, 150:404-411.
    • (1970) J Nerv Ment Dis , vol.150 , pp. 404-411
    • Carney, M.W.P.1    Sheffield, B.F.2
  • 22
    • 0036713531 scopus 로고    scopus 로고
    • Folic acid intake from fortification in United States exceeds predictions
    • Choumenkovitch S.F., Selhub J., Wilson P.W.F., et al. Folic acid intake from fortification in United States exceeds predictions. J Nutr 2002, 132:2792-2798.
    • (2002) J Nutr , vol.132 , pp. 2792-2798
    • Choumenkovitch, S.F.1    Selhub, J.2    Wilson, P.W.F.3
  • 23
    • 85057908352 scopus 로고    scopus 로고
    • Genetic variation: effect on folate metabolism and health
    • CRC Press, Boca Raton, L.B. Bailey (Ed.)
    • Christensen K.E., Rozen R. Genetic variation: effect on folate metabolism and health. Folate in Health and Disease 2010, 75-110. CRC Press, Boca Raton. L.B. Bailey (Ed.).
    • (2010) Folate in Health and Disease , pp. 75-110
    • Christensen, K.E.1    Rozen, R.2
  • 24
    • 0031597388 scopus 로고    scopus 로고
    • Folate, vitamin B12, and serum total homocysteine levels in confirmed Alzheimer disease
    • Clarke R., Smith A.D., Jobst K.A., et al. Folate, vitamin B12, and serum total homocysteine levels in confirmed Alzheimer disease. Arch Neurol 1998, 55:1449-1455.
    • (1998) Arch Neurol , vol.55 , pp. 1449-1455
    • Clarke, R.1    Smith, A.D.2    Jobst, K.A.3
  • 25
    • 0037164104 scopus 로고    scopus 로고
    • Homocysteine and risk of heart disease and stroke: a meta-analysis
    • Clarke R., Collins R., Lewington S. Homocysteine and risk of heart disease and stroke: a meta-analysis. JAMA 2002, 288:2015-2022.
    • (2002) JAMA , vol.288 , pp. 2015-2022
    • Clarke, R.1    Collins, R.2    Lewington, S.3
  • 26
    • 9144237420 scopus 로고    scopus 로고
    • Vitamin B12 and folate deficiency in later life
    • Clarke R., Grimley Evans J., Schneede J., et al. Vitamin B12 and folate deficiency in later life. Age Ageing 2004, 33:34-41.
    • (2004) Age Ageing , vol.33 , pp. 34-41
    • Clarke, R.1    Grimley Evans, J.2    Schneede, J.3
  • 27
    • 53649093801 scopus 로고    scopus 로고
    • Folate and vitamin B12 status in relation to cognitive impairment and anaemia in the setting of voluntary fortification in the UK
    • Clarke R., Sherliker P., Hin H., et al. Folate and vitamin B12 status in relation to cognitive impairment and anaemia in the setting of voluntary fortification in the UK. Br J Nutr 2008, 100:1054-1059.
    • (2008) Br J Nutr , vol.100 , pp. 1054-1059
    • Clarke, R.1    Sherliker, P.2    Hin, H.3
  • 28
    • 0033858407 scopus 로고    scopus 로고
    • Enhancement of the antidepressant action of fluoxetine by folic acid: a randomised, placebo controlled trial
    • Coppen A., Bailey J. Enhancement of the antidepressant action of fluoxetine by folic acid: a randomised, placebo controlled trial. J Affect Disord 2000, 60:121-130.
    • (2000) J Affect Disord , vol.60 , pp. 121-130
    • Coppen, A.1    Bailey, J.2
  • 29
  • 31
    • 0015699815 scopus 로고
    • Facilitatory and direct excitatory effects of folate and folinate on single neurons of cat cerebral cortex
    • Davis J., Watkins J.C. Facilitatory and direct excitatory effects of folate and folinate on single neurons of cat cerebral cortex. Biochem Pharmacol 1973, 22:1667-1668.
    • (1973) Biochem Pharmacol , vol.22 , pp. 1667-1668
    • Davis, J.1    Watkins, J.C.2
  • 32
    • 84859889194 scopus 로고    scopus 로고
    • Cognitive and clinical outcomes of homocysteine-lowering B-vitamin treatment in mild cognitive impairment: a randomised controlled trial
    • de Jager C.A., Oulhaj A., Jacoby R., et al. Cognitive and clinical outcomes of homocysteine-lowering B-vitamin treatment in mild cognitive impairment: a randomised controlled trial. Int J Geriatr Psychiatry 2012, 27:592-600.
    • (2012) Int J Geriatr Psychiatry , vol.27 , pp. 592-600
    • de Jager, C.A.1    Oulhaj, A.2    Jacoby, R.3
  • 33
    • 0037226674 scopus 로고    scopus 로고
    • Homocysteine and brain atrophy on MRI of non-demented elderly
    • den Heijer T., Vermeer S.E., Clarke R., et al. Homocysteine and brain atrophy on MRI of non-demented elderly. Brain 2003, 126:170-175.
    • (2003) Brain , vol.126 , pp. 170-175
    • den Heijer, T.1    Vermeer, S.E.2    Clarke, R.3
  • 34
    • 0038476110 scopus 로고    scopus 로고
    • Pernicious anaemia with neuropsychiatric dysfunction in a patient with sickle cell anaemia treated with folate supplementation
    • Dhar M., Bellevue R., Carmel R. Pernicious anaemia with neuropsychiatric dysfunction in a patient with sickle cell anaemia treated with folate supplementation. N Engl J Med 2003, 348:2204-2207.
    • (2003) N Engl J Med , vol.348 , pp. 2204-2207
    • Dhar, M.1    Bellevue, R.2    Carmel, R.3
  • 35
    • 0029067620 scopus 로고
    • Does folic acid harm people with vitamin B12 deficiency?
    • Dickinson C.J. Does folic acid harm people with vitamin B12 deficiency?. Q J Med 1995, 88:357-364.
    • (1995) Q J Med , vol.88 , pp. 357-364
    • Dickinson, C.J.1
  • 36
    • 29844443889 scopus 로고    scopus 로고
    • Folate and the methylenetetrahydrofolate reductase 677C→T mutation correlate with cognitive performance
    • Durga J., van Boxtel M.P.J., Schouten E.G., et al. Folate and the methylenetetrahydrofolate reductase 677C→T mutation correlate with cognitive performance. Neurobiol Aging 2006, 27:334-343.
    • (2006) Neurobiol Aging , vol.27 , pp. 334-343
    • Durga, J.1    van Boxtel, M.P.J.2    Schouten, E.G.3
  • 37
    • 33846211794 scopus 로고    scopus 로고
    • Effect of 3-year folic acid supplementation on cognitive function in older adults in the FACIT trial: a randomised, double blind, controlled trial
    • Durga J., van Boxtel M.P.J., Schouten E.G., et al. Effect of 3-year folic acid supplementation on cognitive function in older adults in the FACIT trial: a randomised, double blind, controlled trial. Lancet 2007, 369:208-216.
    • (2007) Lancet , vol.369 , pp. 208-216
    • Durga, J.1    van Boxtel, M.P.J.2    Schouten, E.G.3
  • 39
    • 0036229212 scopus 로고    scopus 로고
    • Homocysteine, B vitamin status, and cognitive function in the elderly
    • Duthie S.J., Whalley L.J., Collins A.R., et al. Homocysteine, B vitamin status, and cognitive function in the elderly. Am J Clin Nutr 2002, 75:908-913.
    • (2002) Am J Clin Nutr , vol.75 , pp. 908-913
    • Duthie, S.J.1    Whalley, L.J.2    Collins, A.R.3
  • 40
    • 0030614878 scopus 로고    scopus 로고
    • Folate, vitamin B12, and homocysteine in major depressive disorder
    • Fava M., Borus J.S., Alpert J.E., et al. Folate, vitamin B12, and homocysteine in major depressive disorder. Am J Psychiatry 1997, 154:426-428.
    • (1997) Am J Psychiatry , vol.154 , pp. 426-428
    • Fava, M.1    Borus, J.S.2    Alpert, J.E.3
  • 41
    • 0030810077 scopus 로고    scopus 로고
    • Low folate levels in the cognitive decline of elderly patients and the efficacy of folate as a treatment for improving memory deficits
    • Fioravanti M., Ferrario E., Massaia M., et al. Low folate levels in the cognitive decline of elderly patients and the efficacy of folate as a treatment for improving memory deficits. Arch Gerontol Geriatr 1997, 26:1-13.
    • (1997) Arch Gerontol Geriatr , vol.26 , pp. 1-13
    • Fioravanti, M.1    Ferrario, E.2    Massaia, M.3
  • 42
    • 0036328453 scopus 로고    scopus 로고
    • Gene nutrient interactions and DNA methylation
    • Friso S., Choi S.-W. Gene nutrient interactions and DNA methylation. J Nutr 2002, 132:2382S-2387S.
    • (2002) J Nutr , vol.132
    • Friso, S.1    Choi, S.-W.2
  • 43
    • 10644237168 scopus 로고    scopus 로고
    • S-adenosylmethionine/homocysteine cycle alterations modify DNA methylation status with consequent deregulation of PS1 and BACE and beta-amyloid production
    • Fuso A., Seminara L., Cavallaro R.A., et al. S-adenosylmethionine/homocysteine cycle alterations modify DNA methylation status with consequent deregulation of PS1 and BACE and beta-amyloid production. Mol Cell Neurosci 2005, 28:195-204.
    • (2005) Mol Cell Neurosci , vol.28 , pp. 195-204
    • Fuso, A.1    Seminara, L.2    Cavallaro, R.A.3
  • 44
    • 41249098662 scopus 로고    scopus 로고
    • B-vitamin deprivation induces hyperhomocysteinemia and brain S-adenosylhomocysteinemia, depletes brain S-adenosylmethionine, and enhances PSI and BACE expression and amyloid-beta deposition in mice
    • Fuso A., Nicolia V., Cavallaro R.A., et al. B-vitamin deprivation induces hyperhomocysteinemia and brain S-adenosylhomocysteinemia, depletes brain S-adenosylmethionine, and enhances PSI and BACE expression and amyloid-beta deposition in mice. Mol Cell Neurosci 2008, 37:731-746.
    • (2008) Mol Cell Neurosci , vol.37 , pp. 731-746
    • Fuso, A.1    Nicolia, V.2    Cavallaro, R.A.3
  • 45
    • 0025113543 scopus 로고
    • Enhancement of recovery from psychiatric illness by methyl folate
    • Godfrey P.S.A., Toone B.K., Carney M.W.P., et al. Enhancement of recovery from psychiatric illness by methyl folate. Lancet 1990, 336:392-395.
    • (1990) Lancet , vol.336 , pp. 392-395
    • Godfrey, P.S.A.1    Toone, B.K.2    Carney, M.W.P.3
  • 46
    • 0020582844 scopus 로고
    • Association between nutritional status and cognitive functioning in a healthy elderly population
    • Goodwin J.S., Goodwin J.M., Garry P.J. Association between nutritional status and cognitive functioning in a healthy elderly population. JAMA 1983, 249:2917-2921.
    • (1983) JAMA , vol.249 , pp. 2917-2921
    • Goodwin, J.S.1    Goodwin, J.M.2    Garry, P.J.3
  • 47
    • 3643068907 scopus 로고
    • Folate deficiency and neurological disease
    • Grant H.C., Hoffbrand A.V., Wells D.G. Folate deficiency and neurological disease. Lancet 1965, 2:763-767.
    • (1965) Lancet , vol.2 , pp. 763-767
    • Grant, H.C.1    Hoffbrand, A.V.2    Wells, D.G.3
  • 48
    • 0001108043 scopus 로고
    • Experience with pteroylglutamic (synthetic folic) acid in the treatment of pernicious anaemia
    • Hall B.E., Watkins C.H. Experience with pteroylglutamic (synthetic folic) acid in the treatment of pernicious anaemia. J Lab Clin Med 1947, 32:622-634.
    • (1947) J Lab Clin Med , vol.32 , pp. 622-634
    • Hall, B.E.1    Watkins, C.H.2
  • 49
    • 0032860430 scopus 로고    scopus 로고
    • Further evidence on the effects of vitamin B12 and folate levels on episodic memory functioning; a population-based study of healthy very old adults
    • Hassing L., Wahlin A., Winblad B., et al. Further evidence on the effects of vitamin B12 and folate levels on episodic memory functioning; a population-based study of healthy very old adults. Biol Psychiatry 1999, 45:1472-1480.
    • (1999) Biol Psychiatry , vol.45 , pp. 1472-1480
    • Hassing, L.1    Wahlin, A.2    Winblad, B.3
  • 50
    • 0025939341 scopus 로고
    • Neurologic aspects of cobalamin deficiency
    • Healton E.B., Savage D.G., Brust J.C.M., et al. Neurologic aspects of cobalamin deficiency. Medicine 1991, 70:229-245.
    • (1991) Medicine , vol.70 , pp. 229-245
    • Healton, E.B.1    Savage, D.G.2    Brust, J.C.M.3
  • 51
    • 0034735832 scopus 로고    scopus 로고
    • Folic acid antagonists during pregnancy and the risk of birth defects
    • Hernandez-Diaz S., Werler M.M., Walker A.M., et al. Folic acid antagonists during pregnancy and the risk of birth defects. N Engl J Med 2000, 343:1608-1614.
    • (2000) N Engl J Med , vol.343 , pp. 1608-1614
    • Hernandez-Diaz, S.1    Werler, M.M.2    Walker, A.M.3
  • 52
    • 84981812991 scopus 로고
    • The role of folic acid in pregnancy, with particular reference to anaemia, abruption and abortion
    • Hibbard B.M. The role of folic acid in pregnancy, with particular reference to anaemia, abruption and abortion. J Obstet Gynaecol Br Commonw 1964, 71:529-542.
    • (1964) J Obstet Gynaecol Br Commonw , vol.71 , pp. 529-542
    • Hibbard, B.M.1
  • 53
    • 79956320401 scopus 로고    scopus 로고
    • Folate status and birth defect risk: epidemiological perspective
    • CRC Press, Boca Raton, L.B. Bailey (Ed.)
    • Hobbs C.A., Shaw G.M., Werler M., et al. Folate status and birth defect risk: epidemiological perspective. Folate in Health and Disease 2010, 133-153. CRC Press, Boca Raton. L.B. Bailey (Ed.).
    • (2010) Folate in Health and Disease , pp. 133-153
    • Hobbs, C.A.1    Shaw, G.M.2    Werler, M.3
  • 54
    • 0015902596 scopus 로고
    • Epileptogenic activity of sodium-folate and the blood brain barrier in the rat
    • Hommes O.R., Obbens E.A.M.T., Wijfels C.C.B. Epileptogenic activity of sodium-folate and the blood brain barrier in the rat. J Neurol Sci 1973, 19:63-71.
    • (1973) J Neurol Sci , vol.19 , pp. 63-71
    • Hommes, O.R.1    Obbens, E.A.M.T.2    Wijfels, C.C.B.3
  • 55
    • 0002538486 scopus 로고
    • Convulsant properties of folate compounds; some considerations and speculations
    • Raven Press, New York, M.I. Botez, E.H. Reynolds (Eds.)
    • Hommes O.R., Hollinger J.L., Jansen M.J.T., et al. Convulsant properties of folate compounds; some considerations and speculations. Folic Acid in Neurology, Psychiatry and Internal Medicine 1979, 285-316. Raven Press, New York. M.I. Botez, E.H. Reynolds (Eds.).
    • (1979) Folic Acid in Neurology, Psychiatry and Internal Medicine , pp. 285-316
    • Hommes, O.R.1    Hollinger, J.L.2    Jansen, M.J.T.3
  • 56
    • 27244443366 scopus 로고    scopus 로고
    • Hyperhomocysteinemia in children treated with antiepileptic drugs is normalised by folic acid supplementation
    • Huemer M., Ausserer B., Graninger G., et al. Hyperhomocysteinemia in children treated with antiepileptic drugs is normalised by folic acid supplementation. Epilepsia 2005, 46:1677-1683.
    • (2005) Epilepsia , vol.46 , pp. 1677-1683
    • Huemer, M.1    Ausserer, B.2    Graninger, G.3
  • 57
    • 27644544906 scopus 로고    scopus 로고
    • Association of homocysteine with plasma amyloid β protein in aging and neurodegenerative disease
    • Irizarry M.C., Gurol M.E., Raju S., et al. Association of homocysteine with plasma amyloid β protein in aging and neurodegenerative disease. Neurology 2005, 65:1402-1408.
    • (2005) Neurology , vol.65 , pp. 1402-1408
    • Irizarry, M.C.1    Gurol, M.E.2    Raju, S.3
  • 58
    • 3843098227 scopus 로고    scopus 로고
    • Folic acid supplementation enhances repair in the adult central nervous system
    • Iskandar B.J., Nelson A., Resnick D., et al. Folic acid supplementation enhances repair in the adult central nervous system. Ann Neurol 2004, 56:221-227.
    • (2004) Ann Neurol , vol.56 , pp. 221-227
    • Iskandar, B.J.1    Nelson, A.2    Resnick, D.3
  • 59
    • 77951810285 scopus 로고    scopus 로고
    • Folate regulation of axonal regeneration in the rodent central nervous system through DNA methylation
    • Iskandar B.J., Rizk E., Meier B., et al. Folate regulation of axonal regeneration in the rodent central nervous system through DNA methylation. J Clin Invest 2010, 120:1603-1616.
    • (2010) J Clin Invest , vol.120 , pp. 1603-1616
    • Iskandar, B.J.1    Rizk, E.2    Meier, B.3
  • 60
    • 84860282551 scopus 로고    scopus 로고
    • Folate and vascular disease: epidemiological perspective
    • CRC Press, Boca Raton, L.B. Bailey (Ed.)
    • Kalin S.R., Rimm E.B. Folate and vascular disease: epidemiological perspective. Folate in Health and Disease 2010, 263-290. CRC Press, Boca Raton. L.B. Bailey (Ed.).
    • (2010) Folate in Health and Disease , pp. 263-290
    • Kalin, S.R.1    Rimm, E.B.2
  • 61
    • 48249094979 scopus 로고    scopus 로고
    • Changes in folate, vitamin B12 and homocysteine associated with incident dementia
    • Kim J.M., Stewart R., Kim S.W., et al. Changes in folate, vitamin B12 and homocysteine associated with incident dementia. J Neurol Neurosurg Psychiatry 2008, 79:864-868.
    • (2008) J Neurol Neurosurg Psychiatry , vol.79 , pp. 864-868
    • Kim, J.M.1    Stewart, R.2    Kim, S.W.3
  • 63
    • 77951869356 scopus 로고    scopus 로고
    • Neuronal injury: folate to the rescue?
    • Kronenberg G., Endres M. Neuronal injury: folate to the rescue?. J Clin Invest 2010, 120:1383-1386.
    • (2010) J Clin Invest , vol.120 , pp. 1383-1386
    • Kronenberg, G.1    Endres, M.2
  • 64
    • 0036523032 scopus 로고    scopus 로고
    • Folic acid deficiency and homocysteine impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer's disease
    • Kruman I.I., Kumaravel T.S., Lohani A., et al. Folic acid deficiency and homocysteine impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer's disease. J Neurosci 2002, 22:1752-1762.
    • (2002) J Neurosci , vol.22 , pp. 1752-1762
    • Kruman, I.I.1    Kumaravel, T.S.2    Lohani, A.3
  • 65
    • 0018070010 scopus 로고
    • Myeloneurophathy after prolonged exposure to nitrous oxide
    • Layzer R.B. Myeloneurophathy after prolonged exposure to nitrous oxide. Lancet 1978, 2:1227-1230.
    • (1978) Lancet , vol.2 , pp. 1227-1230
    • Layzer, R.B.1
  • 66
    • 33645409496 scopus 로고
    • Progressive perniciöse anämie bei tabeskranken
    • Leichtenstern O. Progressive perniciöse anämie bei tabeskranken. Dtsch Med Wochenschr 1884, 10:849-850.
    • (1884) Dtsch Med Wochenschr , vol.10 , pp. 849-850
    • Leichtenstern, O.1
  • 67
    • 33645527632 scopus 로고    scopus 로고
    • The thermolabile variant of MTHFR is associated with depression in the British Women's Heart and Health Study and a metaanalysis
    • Lewis S.J., Lawlor D.A., Davey Smith G., et al. The thermolabile variant of MTHFR is associated with depression in the British Women's Heart and Health Study and a metaanalysis. Mol Psychiatry 2006, 11:352-360.
    • (2006) Mol Psychiatry , vol.11 , pp. 352-360
    • Lewis, S.J.1    Lawlor, D.A.2    Davey Smith, G.3
  • 68
    • 0006636741 scopus 로고
    • Zur kenntniss der perniciösen anämie
    • Lichtheim L. Zur kenntniss der perniciösen anämie. Munch Med Wochenschr 1887, 34:301-306.
    • (1887) Munch Med Wochenschr , vol.34 , pp. 301-306
    • Lichtheim, L.1
  • 69
    • 0023946537 scopus 로고
    • Neuropsychiatric disorders caused by cobalamin deficiency in the absence of anaemia or macrocytosis
    • Lindenbaum J., Healton E.B., Savage D.G., et al. Neuropsychiatric disorders caused by cobalamin deficiency in the absence of anaemia or macrocytosis. N Engl J Med 1988, 318:1720-1728.
    • (1988) N Engl J Med , vol.318 , pp. 1720-1728
    • Lindenbaum, J.1    Healton, E.B.2    Savage, D.G.3
  • 70
    • 0742304414 scopus 로고    scopus 로고
    • Is folic acid the ultimate functional food component for disease prevention?
    • Lucock M. Is folic acid the ultimate functional food component for disease prevention?. BMJ 2004, 328:211-214.
    • (2004) BMJ , vol.328 , pp. 211-214
    • Lucock, M.1
  • 71
    • 0017082339 scopus 로고
    • Folate-responsive neuropathy: a report of ten cases
    • Manzoor M., Runcie J. Folate-responsive neuropathy: a report of ten cases. BMJ 1976, 1:1176-1178.
    • (1976) BMJ , vol.1 , pp. 1176-1178
    • Manzoor, M.1    Runcie, J.2
  • 72
    • 1942528615 scopus 로고    scopus 로고
    • Humana Press, Totowa, New Jersey, E.J. Massaro, J.M. Rogers (Eds.)
    • Folate and Human Development 2002, Humana Press, Totowa, New Jersey. E.J. Massaro, J.M. Rogers (Eds.).
    • (2002) Folate and Human Development
  • 73
    • 0037364417 scopus 로고    scopus 로고
    • Folate and homocysteine metabolism in neural plasticity and neurodegenerative disorders
    • Mattson M.P., Shea T.B. Folate and homocysteine metabolism in neural plasticity and neurodegenerative disorders. Trends Neurosci 2003, 26:137-146.
    • (2003) Trends Neurosci , vol.26 , pp. 137-146
    • Mattson, M.P.1    Shea, T.B.2
  • 74
    • 0037305028 scopus 로고    scopus 로고
    • Alzheimer's disease and total plasma aminothiols
    • McCaddon A., Hudson P., Hill D., et al. Alzheimer's disease and total plasma aminothiols. Biol Psychiatry 2003, 53:254-260.
    • (2003) Biol Psychiatry , vol.53 , pp. 254-260
    • McCaddon, A.1    Hudson, P.2    Hill, D.3
  • 75
    • 0036792804 scopus 로고    scopus 로고
    • Moderately elevated plasma homocysteine, methylenetetrahydrofolate reductase genotype, and risk for stroke, vascular dementia, and Alzheimer disease in Northern Ireland
    • McIlroy S.P., Dynan K.B., Lawson J.T., et al. Moderately elevated plasma homocysteine, methylenetetrahydrofolate reductase genotype, and risk for stroke, vascular dementia, and Alzheimer disease in Northern Ireland. Stroke 2002, 3:2351-2356.
    • (2002) Stroke , vol.3 , pp. 2351-2356
    • McIlroy, S.P.1    Dynan, K.B.2    Lawson, J.T.3
  • 76
    • 4243595082 scopus 로고
    • Predisposition of laboratory animals to epileptogenic activity of folic acid
    • Raven Press, New York, M.I. Botez, E.H. Reynolds (Eds.)
    • Miller A.A., Goff D., Webster R.A. Predisposition of laboratory animals to epileptogenic activity of folic acid. Folic Acid in Neurology, Psychiatry and Internal Medicine 1979, 331-334. Raven Press, New York. M.I. Botez, E.H. Reynolds (Eds.).
    • (1979) Folic Acid in Neurology, Psychiatry and Internal Medicine , pp. 331-334
    • Miller, A.A.1    Goff, D.2    Webster, R.A.3
  • 77
    • 0038387939 scopus 로고    scopus 로고
    • Homocysteine and Alzheimer's disease
    • Morris M.S. Homocysteine and Alzheimer's disease. Lancet Neurol 2003, 2:425-428.
    • (2003) Lancet Neurol , vol.2 , pp. 425-428
    • Morris, M.S.1
  • 78
    • 84865113946 scopus 로고    scopus 로고
    • Folate and neurological function: epidemiological perspective
    • CRC Press, Boca Raton, L.B. Bailey (Ed.)
    • Morris M.S., Jacques P.F. Folate and neurological function: epidemiological perspective. Folate in Health and Disease 2010, 325-353. CRC Press, Boca Raton. L.B. Bailey (Ed.).
    • (2010) Folate in Health and Disease , pp. 325-353
    • Morris, M.S.1    Jacques, P.F.2
  • 79
    • 33846102164 scopus 로고    scopus 로고
    • Folate and vitamin B-12 status in relation to anaemia, macrocytosis, and cognitive impairment in older Americans in the age of folic acid fortification
    • Morris M.S., Jacques P.F., Rosenberg I.H., et al. Folate and vitamin B-12 status in relation to anaemia, macrocytosis, and cognitive impairment in older Americans in the age of folic acid fortification. Am J Clin Nutr 2007, 85:193-200.
    • (2007) Am J Clin Nutr , vol.85 , pp. 193-200
    • Morris, M.S.1    Jacques, P.F.2    Rosenberg, I.H.3
  • 80
    • 84865150749 scopus 로고    scopus 로고
    • Vitamin B-12 and folate status in relation to decline in scores on the mini-mental state examination in the Framingham heart study
    • Morris M.S., Selhub J., Jacques P.F. Vitamin B-12 and folate status in relation to decline in scores on the mini-mental state examination in the Framingham heart study. J Am Geriatr Soc 2012, 60:1457-1464.
    • (2012) J Am Geriatr Soc , vol.60 , pp. 1457-1464
    • Morris, M.S.1    Selhub, J.2    Jacques, P.F.3
  • 81
    • 65449126327 scopus 로고    scopus 로고
    • Folic acid use and major congenital malformations in offspring of women with epilepsy: a prospective study from the UK Epilepsy and Pregnancy Register
    • Morrow J.I., Hunt S.J., Russell A.J., et al. Folic acid use and major congenital malformations in offspring of women with epilepsy: a prospective study from the UK Epilepsy and Pregnancy Register. J Neurol Neurosurg Psychiatry 2009, 80:506-511.
    • (2009) J Neurol Neurosurg Psychiatry , vol.80 , pp. 506-511
    • Morrow, J.I.1    Hunt, S.J.2    Russell, A.J.3
  • 82
    • 0025863475 scopus 로고
    • Prevention of neural tube defects: results of the Medical Research Council Vitamin Study
    • MRC Vitamin Study Group
    • MRC Vitamin Study Group Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. Lancet 1991, 338:131-137.
    • (1991) Lancet , vol.338 , pp. 131-137
  • 83
    • 0035915621 scopus 로고    scopus 로고
    • Pathological correlates of late-onset dementia in a multicentre, community-based population in England and Wales
    • Neuropathology Group of the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS)
    • Neuropathology Group of the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS) Pathological correlates of late-onset dementia in a multicentre, community-based population in England and Wales. Lancet 2001, 357:169-175.
    • (2001) Lancet , vol.357 , pp. 169-175
  • 84
    • 20244369426 scopus 로고    scopus 로고
    • Mielopatia por déficit de vitamina B12: caracterizatión clinica de 11 cases
    • 2004
    • Nogales-Gaete J., Jiménez P.P., Garcia P.F., et al. Mielopatia por déficit de vitamina B12: caracterizatión clinica de 11 cases. Rev Med Chil 2004, 132:1377-1382. 2004.
    • (2004) Rev Med Chil , vol.132 , pp. 1377-1382
    • Nogales-Gaete, J.1    Jiménez, P.P.2    Garcia, P.F.3
  • 85
    • 0023082888 scopus 로고
    • Clinical aspects of the interaction between nitrous oxide and vitamin B12
    • 1987
    • Nunn J.F. Clinical aspects of the interaction between nitrous oxide and vitamin B12. Br J Anaesth 1987, 59:3-13. 1987.
    • (1987) Br J Anaesth , vol.59 , pp. 3-13
    • Nunn, J.F.1
  • 86
    • 0031779446 scopus 로고    scopus 로고
    • Remethylation defects: guidelines for clinical diagnosis and treatment
    • Ogier de Baulny H., Gérard M., Saudubray J.M., et al. Remethylation defects: guidelines for clinical diagnosis and treatment. Eur J Pediatr 1998, 157:S77-S83.
    • (1998) Eur J Pediatr , vol.157
    • Ogier de Baulny, H.1    Gérard, M.2    Saudubray, J.M.3
  • 87
    • 25644442845 scopus 로고    scopus 로고
    • The relationship between serum folate, vitamin B12, and homocysteine levels in major depressive disorder and the timing of improvement with fluoxetine
    • Papakostas G.I., Petersen T., Lebowitz B.D., et al. The relationship between serum folate, vitamin B12, and homocysteine levels in major depressive disorder and the timing of improvement with fluoxetine. Int J Neuropsychopharmacol 2005, 8:1-6.
    • (2005) Int J Neuropsychopharmacol , vol.8 , pp. 1-6
    • Papakostas, G.I.1    Petersen, T.2    Lebowitz, B.D.3
  • 88
    • 84871824309 scopus 로고    scopus 로고
    • L-methylfolate as adjunctive therapy for SSRI-resistant major depression
    • Papakostas G.I., Shelton R.C., Zajecka J.M., et al. L-methylfolate as adjunctive therapy for SSRI-resistant major depression. Am J Psychiatry 2012, 169:1267-1274.
    • (2012) Am J Psychiatry , vol.169 , pp. 1267-1274
    • Papakostas, G.I.1    Shelton, R.C.2    Zajecka, J.M.3
  • 89
    • 0027502712 scopus 로고
    • Oral 5'-methyltetrahydrofolic acid in senile organic mental disorders with depression: results of a double-blind multicenter study
    • Passeri M., Cuciniotta D., Abate G., et al. Oral 5'-methyltetrahydrofolic acid in senile organic mental disorders with depression: results of a double-blind multicenter study. Ageing Clin Exp Res 1993, 5:63-71.
    • (1993) Ageing Clin Exp Res , vol.5 , pp. 63-71
    • Passeri, M.1    Cuciniotta, D.2    Abate, G.3
  • 90
    • 0001799146 scopus 로고
    • Folic acid deficiency: a cause of subacute combined degeneration
    • Raven Press, New York, M.I. Botez, E.H. Reynolds (Eds.)
    • Pincus J.H. Folic acid deficiency: a cause of subacute combined degeneration. Folic Acid in Neurology, Psychiatry and Internal Medicine 1979, 427-433. Raven Press, New York. M.I. Botez, E.H. Reynolds (Eds.).
    • (1979) Folic Acid in Neurology, Psychiatry and Internal Medicine , pp. 427-433
    • Pincus, J.H.1
  • 91
    • 0015530943 scopus 로고
    • Subacute combined system degeneration with folate deficiency
    • Pincus J.H., Reynolds E.H., Glaser G.H. Subacute combined system degeneration with folate deficiency. JAMA 1972, 221:496-497.
    • (1972) JAMA , vol.221 , pp. 496-497
    • Pincus, J.H.1    Reynolds, E.H.2    Glaser, G.H.3
  • 92
    • 0037069282 scopus 로고    scopus 로고
    • Homocysteine and cognitive function in the elderly: the Rotterdam scan study
    • Prins N.D., den Heijer T., Hofman A., et al. Homocysteine and cognitive function in the elderly: the Rotterdam scan study. Neurology 2002, 59:1375-1380.
    • (2002) Neurology , vol.59 , pp. 1375-1380
    • Prins, N.D.1    den Heijer, T.2    Hofman, A.3
  • 94
    • 18344395924 scopus 로고    scopus 로고
    • Autoantibodies to folate receptors in the cerebral folate deficiency syndrome
    • Ramaekers V.T., Rothenberg P., Sequeira J.M., et al. Autoantibodies to folate receptors in the cerebral folate deficiency syndrome. N Engl J Med 2005, 352:1985-1991.
    • (2005) N Engl J Med , vol.352 , pp. 1985-1991
    • Ramaekers, V.T.1    Rothenberg, P.2    Sequeira, J.M.3
  • 95
    • 5144231634 scopus 로고    scopus 로고
    • Plasma folate concentrations are associated with depressive symptoms in elderly Latina women despite folic acid fortification
    • Ramos M.I., Allen L.H., Haan M.N., et al. Plasma folate concentrations are associated with depressive symptoms in elderly Latina women despite folic acid fortification. Am J Clin Nutr 2004, 80:1024-1028.
    • (2004) Am J Clin Nutr , vol.80 , pp. 1024-1028
    • Ramos, M.I.1    Allen, L.H.2    Haan, M.N.3
  • 96
    • 33644689953 scopus 로고    scopus 로고
    • Low folate status is associated with impaired cognitive function and dementia in the Sacramento area Latino study on aging
    • Ramos M.I., Allen L.H., Mungas D.M., et al. Low folate status is associated with impaired cognitive function and dementia in the Sacramento area Latino study on aging. Am J Clin Nutr 2005, 82:1346-1352.
    • (2005) Am J Clin Nutr , vol.82 , pp. 1346-1352
    • Ramos, M.I.1    Allen, L.H.2    Mungas, D.M.3
  • 97
    • 0033805888 scopus 로고    scopus 로고
    • Genomic DNA methylation decreases in response to moderate folate depletion in elderly women
    • Rampersaud G.C., Kauwell G.P.A., Hutson A.D., et al. Genomic DNA methylation decreases in response to moderate folate depletion in elderly women. Am J Clin Nutr 2000, 72:998-1003.
    • (2000) Am J Clin Nutr , vol.72 , pp. 998-1003
    • Rampersaud, G.C.1    Kauwell, G.P.A.2    Hutson, A.D.3
  • 98
    • 27244445944 scopus 로고    scopus 로고
    • Homocystine and folate as risk factors for dementia and Alzheimer disease
    • Ravaglia G., Forti P., Maioli F., et al. Homocystine and folate as risk factors for dementia and Alzheimer disease. Am J Clin Nutr 2005, 82:636-643.
    • (2005) Am J Clin Nutr , vol.82 , pp. 636-643
    • Ravaglia, G.1    Forti, P.2    Maioli, F.3
  • 99
    • 0344837893 scopus 로고    scopus 로고
    • Vitamin B12 insufficiency and the risk of foetal neural tube defects
    • Ray J.G., Blom H.J. Vitamin B12 insufficiency and the risk of foetal neural tube defects. QJ Med 2003, 96:289-295.
    • (2003) QJ Med , vol.96 , pp. 289-295
    • Ray, J.G.1    Blom, H.J.2
  • 100
    • 0014294012 scopus 로고
    • Mental effects of anticonvulsants, and folic acid metabolism
    • Reynolds E.H. Mental effects of anticonvulsants, and folic acid metabolism. Brain 1968, 91:197-214.
    • (1968) Brain , vol.91 , pp. 197-214
    • Reynolds, E.H.1
  • 101
    • 0017011221 scopus 로고
    • Neurological aspects of folate and vitamin B12 metabolism
    • Saunders, London, A.V. Hoffbrand (Ed.)
    • Reynolds E.H. Neurological aspects of folate and vitamin B12 metabolism. Clinics in Haematology 1976, Vol. 5:661-696. Saunders, London. A.V. Hoffbrand (Ed.).
    • (1976) Clinics in Haematology , vol.5 , pp. 661-696
    • Reynolds, E.H.1
  • 102
    • 4243892309 scopus 로고
    • Folic acid, vitamin B12 and the nervous system: historical aspects
    • Raven Press, New York, M.I. Botez, E.H. Reynolds (Eds.)
    • Reynolds E.H. Folic acid, vitamin B12 and the nervous system: historical aspects. Folic Acid in Neurology, Psychiatry, and Internal Medicine 1979, 1-5. Raven Press, New York. M.I. Botez, E.H. Reynolds (Eds.).
    • (1979) Folic Acid in Neurology, Psychiatry, and Internal Medicine , pp. 1-5
    • Reynolds, E.H.1
  • 103
    • 0345360382 scopus 로고
    • Interrelationships between the neurology of folate and vitamin B12 deficiency
    • Raven Press, New York, M.I. Botez, E.H. Reynolds (Eds.)
    • Reynolds E.H. Interrelationships between the neurology of folate and vitamin B12 deficiency. Folic Acid in Neurology, Psychiatry and Internal Medicine 1979, 501-515. Raven Press, New York. M.I. Botez, E.H. Reynolds (Eds.).
    • (1979) Folic Acid in Neurology, Psychiatry and Internal Medicine , pp. 501-515
    • Reynolds, E.H.1
  • 104
    • 0037157563 scopus 로고    scopus 로고
    • Folic acid, ageing, depression, and dementia
    • Reynolds E.H. Folic acid, ageing, depression, and dementia. BMJ 2002, 324:1512-1515.
    • (2002) BMJ , vol.324 , pp. 1512-1515
    • Reynolds, E.H.1
  • 105
    • 0036237909 scopus 로고    scopus 로고
    • Benefits and risks of folic acid to the nervous system
    • Reynolds E.H. Benefits and risks of folic acid to the nervous system. J Neurol Neurosurg Psychiatry 2002, 72:767-771.
    • (2002) J Neurol Neurosurg Psychiatry , vol.72 , pp. 767-771
    • Reynolds, E.H.1
  • 106
    • 33749685522 scopus 로고    scopus 로고
    • Vitamin B12, folic acid, and the nervous system
    • Reynolds E. Vitamin B12, folic acid, and the nervous system. Lancet Neurol 2006, 5:949-960.
    • (2006) Lancet Neurol , vol.5 , pp. 949-960
    • Reynolds, E.1
  • 107
    • 0014428232 scopus 로고
    • Neuropsychiatric aspects of anti-convulsant megaloblastic anaemia
    • Reynolds E.H., Chanarin I., Matthews D.M. Neuropsychiatric aspects of anti-convulsant megaloblastic anaemia. Lancet 1968, 1:394-397.
    • (1968) Lancet , vol.1 , pp. 394-397
    • Reynolds, E.H.1    Chanarin, I.2    Matthews, D.M.3
  • 108
  • 109
    • 0015514304 scopus 로고
    • Relationship between serum and cerebrospinal fluid folate
    • Reynolds E.H., Gallagher B.B., Mattson R.H., et al. Relationship between serum and cerebrospinal fluid folate. Nature 1972, 240:155-157.
    • (1972) Nature , vol.240 , pp. 155-157
    • Reynolds, E.H.1    Gallagher, B.B.2    Mattson, R.H.3
  • 110
    • 0015786857 scopus 로고
    • Neurological disease associated with folate deficiency
    • Reynolds E.H., Rothfeld P., Pincus J.H. Neurological disease associated with folate deficiency. BMJ 1973, 2:398-400.
    • (1973) BMJ , vol.2 , pp. 398-400
    • Reynolds, E.H.1    Rothfeld, P.2    Pincus, J.H.3
  • 113
    • 0001912321 scopus 로고    scopus 로고
    • Inherited disorders of folate and cobalamin transport and metabolism
    • McGraw-Hill, New York, C.S. Scriver, A.L. Beaudet, W.S. Sly (Eds.)
    • Rosenblatt D.S., Fenton W.A. Inherited disorders of folate and cobalamin transport and metabolism. The Metabolic Basis of Inherited Disease 2001, 3897-3933. McGraw-Hill, New York. 8th edn. C.S. Scriver, A.L. Beaudet, W.S. Sly (Eds.).
    • (2001) The Metabolic Basis of Inherited Disease , pp. 3897-3933
    • Rosenblatt, D.S.1    Fenton, W.A.2
  • 114
    • 0347988053 scopus 로고    scopus 로고
    • Auto-antibodies against folate receptors in women with a pregnancy complicated by a neural-tube defect
    • Rothenberg S.P., da Costa M.P., Sequeria J.M., et al. Auto-antibodies against folate receptors in women with a pregnancy complicated by a neural-tube defect. N Engl J Med 2004, 350:134-142.
    • (2004) N Engl J Med , vol.350 , pp. 134-142
    • Rothenberg, S.P.1    da Costa, M.P.2    Sequeria, J.M.3
  • 115
    • 84963083532 scopus 로고
    • Subacute combined degeneration of the spinal cord
    • Russell J.S.R., Batten F.E., Collier J. Subacute combined degeneration of the spinal cord. Brain 1900, 23:39-110.
    • (1900) Brain , vol.23 , pp. 39-110
    • Russell, J.S.R.1    Batten, F.E.2    Collier, J.3
  • 116
    • 17344366819 scopus 로고    scopus 로고
    • Relationship of homocysteine, folic acid and vitamin B12 with depression in a middle aged community sample
    • Sachdev P.S., Parslow R.A., Lux O., et al. Relationship of homocysteine, folic acid and vitamin B12 with depression in a middle aged community sample. Psychol Med 2005, 35:529-538.
    • (2005) Psychol Med , vol.35 , pp. 529-538
    • Sachdev, P.S.1    Parslow, R.A.2    Lux, O.3
  • 117
    • 0029165415 scopus 로고
    • Neurological complications of acquired cobalamin deficiency: clinical aspects
    • Bailliere Tindall
    • Savage D.G., Lindenbaum J. Neurological complications of acquired cobalamin deficiency: clinical aspects. Bailliere's Clinical Haematology 1995, vol. 8:657-678. Bailliere Tindall.
    • (1995) Bailliere's Clinical Haematology , vol.8 , pp. 657-678
    • Savage, D.G.1    Lindenbaum, J.2
  • 118
    • 0032910781 scopus 로고    scopus 로고
    • Elevated plasma concentrations of homocysteine in antiepileptic drug treatment
    • Schwaninger M., Ringleb P., Winter R., et al. Elevated plasma concentrations of homocysteine in antiepileptic drug treatment. Epilepsia 1999, 40:345-350.
    • (1999) Epilepsia , vol.40 , pp. 345-350
    • Schwaninger, M.1    Ringleb, P.2    Winter, R.3
  • 119
    • 0000726204 scopus 로고
    • The long-term evaluation of folic acid in the treatment of pernicious anaemia
    • Schwartz S.O., Kaplan S.R., Armstrong B.E. The long-term evaluation of folic acid in the treatment of pernicious anaemia. J Lab Clin Med 1950, 35:894-898.
    • (1950) J Lab Clin Med , vol.35 , pp. 894-898
    • Schwartz, S.O.1    Kaplan, S.R.2    Armstrong, B.E.3
  • 120
    • 0028309375 scopus 로고
    • Effects of the disruption of transmethylation in the central nervous system: an animal model
    • Scott J.M., Molloy A.M., Kennedy D.G., et al. Effects of the disruption of transmethylation in the central nervous system: an animal model. Acta Neurol Scand 1994, 154:27S-31S.
    • (1994) Acta Neurol Scand , vol.154
    • Scott, J.M.1    Molloy, A.M.2    Kennedy, D.G.3
  • 121
    • 38049152741 scopus 로고    scopus 로고
    • In vitamin B12 deficiency, higher serum folate is associated with increased total homocysteine and methylmalonic acid concentrations
    • Selhub J., Morris M.S., Jacques P.F. In vitamin B12 deficiency, higher serum folate is associated with increased total homocysteine and methylmalonic acid concentrations. Proc Natl Acad Sci U S A 2007, 104:19995-20000.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 19995-20000
    • Selhub, J.1    Morris, M.S.2    Jacques, P.F.3
  • 122
    • 27444437550 scopus 로고    scopus 로고
    • Homocysteine and methylmolonic acid concentrations in cerebrospinal fluid: relation with age and Alzheimer's disease
    • Serot J.M., Barbe F., Arning E., et al. Homocysteine and methylmolonic acid concentrations in cerebrospinal fluid: relation with age and Alzheimer's disease. J Neurol Neurosurg Psychiatry 2005, 76:1585-1587.
    • (2005) J Neurol Neurosurg Psychiatry , vol.76 , pp. 1585-1587
    • Serot, J.M.1    Barbe, F.2    Arning, E.3
  • 123
    • 0037075257 scopus 로고    scopus 로고
    • Plasma homocysteine as a risk factor for dementia and Alzheimer's disease
    • Seshadri S., Beiser A., Selhub J., et al. Plasma homocysteine as a risk factor for dementia and Alzheimer's disease. N Engl J Med 2002, 346:476-483.
    • (2002) N Engl J Med , vol.346 , pp. 476-483
    • Seshadri, S.1    Beiser, A.2    Selhub, J.3
  • 125
    • 0018942431 scopus 로고
    • The neuropsychiatry of megaloblastic anaemia
    • Shorvon S.D., Carney M.W.P., Chanarin I., et al. The neuropsychiatry of megaloblastic anaemia. BMJ 1980, 281:1036-1038.
    • (1980) BMJ , vol.281 , pp. 1036-1038
    • Shorvon, S.D.1    Carney, M.W.P.2    Chanarin, I.3
  • 126
    • 0019847861 scopus 로고
    • Apparent prevention of neural tube defects by periconceptional vitamin supplementation
    • Smithells R.W., Sheppard S., Schorah C.J., et al. Apparent prevention of neural tube defects by periconceptional vitamin supplementation. Arch Dis Child 1981, 56:911-918.
    • (1981) Arch Dis Child , vol.56 , pp. 911-918
    • Smithells, R.W.1    Sheppard, S.2    Schorah, C.J.3
  • 127
    • 0015657499 scopus 로고
    • Folate status in a geriatric population and its relation to dementia
    • Sneath P., Chanarin I., Hodkinson H.M., et al. Folate status in a geriatric population and its relation to dementia. Age Ageing 1973, 2:177-182.
    • (1973) Age Ageing , vol.2 , pp. 177-182
    • Sneath, P.1    Chanarin, I.2    Hodkinson, H.M.3
  • 128
    • 0034068273 scopus 로고    scopus 로고
    • Serum folate and the severity of atrophy of the neocortex in Alzheimer disease: findings from the nun study
    • Snowdon D.A., Tully C.L., Smith C.D., et al. Serum folate and the severity of atrophy of the neocortex in Alzheimer disease: findings from the nun study. Am J Clin Nutr 2000, 71:993-998.
    • (2000) Am J Clin Nutr , vol.71 , pp. 993-998
    • Snowdon, D.A.1    Tully, C.L.2    Smith, C.D.3
  • 129
    • 0016803068 scopus 로고
    • Folate transport in the central nervous system
    • Spector R., Lorenzo A.V. Folate transport in the central nervous system. Am J Physiol 1975, 229:777-782.
    • (1975) Am J Physiol , vol.229 , pp. 777-782
    • Spector, R.1    Lorenzo, A.V.2
  • 130
    • 85057902868 scopus 로고    scopus 로고
    • Clinical folate deficiency
    • CRC Press, Boca Raton, L.B. Bailey (Ed.)
    • Stabler S.P. Clinical folate deficiency. Folate in Health and Disease 2010, 409-428. CRC Press, Boca Raton. L.B. Bailey (Ed.).
    • (2010) Folate in Health and Disease , pp. 409-428
    • Stabler, S.P.1
  • 131
    • 12444257472 scopus 로고    scopus 로고
    • Vitamin B12, serum folate, and cognitive change between 11 and 79 years
    • Starr J.M., Pattie A., Whiteman M.C., et al. Vitamin B12, serum folate, and cognitive change between 11 and 79 years. J Neurol Neurosurg Psychiatry 2005, 76:291-292.
    • (2005) J Neurol Neurosurg Psychiatry , vol.76 , pp. 291-292
    • Starr, J.M.1    Pattie, A.2    Whiteman, M.C.3
  • 132
    • 69449106758 scopus 로고    scopus 로고
    • Folate receptor alpha defect causes cerebral folate transport deficiency: a treatable neurogenerative disorder associated with disturbed myelin metabolism
    • Steinfeld R., Grapp M., Kraetzner R., et al. Folate receptor alpha defect causes cerebral folate transport deficiency: a treatable neurogenerative disorder associated with disturbed myelin metabolism. Am J Hum Genet 2009, 85:354-363.
    • (2009) Am J Hum Genet , vol.85 , pp. 354-363
    • Steinfeld, R.1    Grapp, M.2    Kraetzner, R.3
  • 133
    • 0014078738 scopus 로고
    • Dementia and folate deficiency
    • Strachan R.W., Henderson J.G. Dementia and folate deficiency. Q J Med 1967, 36:189-204.
    • (1967) Q J Med , vol.36 , pp. 189-204
    • Strachan, R.W.1    Henderson, J.G.2
  • 134
    • 0031778476 scopus 로고    scopus 로고
    • Demyelination and inborn errors of the single carbon transfer pathway
    • Surtees R. Demyelination and inborn errors of the single carbon transfer pathway. Eur J Pediatr 1998, 157:118S-121S.
    • (1998) Eur J Pediatr , vol.157
    • Surtees, R.1
  • 135
    • 9244222563 scopus 로고    scopus 로고
    • Cobalamin and folate responsive disorders
    • MacKeith Press, London, P. Baxter (Ed.) Vitamin Responsive Conditions in Paediatric Neurology
    • Surtees R. Cobalamin and folate responsive disorders. International Review of Child Neurology Series 2001, 96-108. MacKeith Press, London. P. Baxter (Ed.).
    • (2001) International Review of Child Neurology Series , pp. 96-108
    • Surtees, R.1
  • 136
    • 0026334413 scopus 로고
    • Association of demyelination with deficiency of cerebrospinal-fluid S-adenosylmethionine in inborn errors of methyl-transfer pathway
    • Surtees R., Leonard J., Austin S. Association of demyelination with deficiency of cerebrospinal-fluid S-adenosylmethionine in inborn errors of methyl-transfer pathway. Lancet 1991, 338:1550-1554.
    • (1991) Lancet , vol.338 , pp. 1550-1554
    • Surtees, R.1    Leonard, J.2    Austin, S.3
  • 137
    • 27244455440 scopus 로고    scopus 로고
    • High homocysteine and low B vitamins predict cognitive decline in aging men: the Veterans Affairs Normative Aging Study
    • Tucker K.L., Qiao N., Scott T., et al. High homocysteine and low B vitamins predict cognitive decline in aging men: the Veterans Affairs Normative Aging Study. Am J Clin Nutr 2005, 82:627-635.
    • (2005) Am J Clin Nutr , vol.82 , pp. 627-635
    • Tucker, K.L.1    Qiao, N.2    Scott, T.3
  • 138
    • 33744455451 scopus 로고    scopus 로고
    • Genetic variation in genes of folate metabolism and neural tube defect risk
    • van der Linden I.J., Afman L.A., Heil S.G., et al. Genetic variation in genes of folate metabolism and neural tube defect risk. Proc Nutr Soc 2005, 65:1-12.
    • (2005) Proc Nutr Soc , vol.65 , pp. 1-12
    • van der Linden, I.J.1    Afman, L.A.2    Heil, S.G.3
  • 139
    • 33750704194 scopus 로고    scopus 로고
    • The methionine synthase reductase 66A→G polymorphism is a maternal risk factor for spina bifida
    • van der Linden I.J., den Heijer M., Afman L.A., et al. The methionine synthase reductase 66A→G polymorphism is a maternal risk factor for spina bifida. J Mol Med 2006, 84:1047-1054.
    • (2006) J Mol Med , vol.84 , pp. 1047-1054
    • van der Linden, I.J.1    den Heijer, M.2    Afman, L.A.3
  • 140
    • 0035379804 scopus 로고    scopus 로고
    • The influence of serum vitamin B12 and folate status on cognitive functioning in very old age
    • Wahlin T.B.R., Wahlin A., Winblad B., et al. The influence of serum vitamin B12 and folate status on cognitive functioning in very old age. Biol Psychol 2001, 56:247-265.
    • (2001) Biol Psychol , vol.56 , pp. 247-265
    • Wahlin, T.B.R.1    Wahlin, A.2    Winblad, B.3
  • 141
    • 78649867126 scopus 로고    scopus 로고
    • Folate-related birth defects: embryonic consequences of abnormal folate transport and metabolism
    • CRC Press, Boca Raton, L.B. Bailey (Ed.)
    • Wallis D., Ballard J.L., Shaw G.M., et al. Folate-related birth defects: embryonic consequences of abnormal folate transport and metabolism. Folate in Health and Disease 2010, 155-178. CRC Press, Boca Raton. L.B. Bailey (Ed.).
    • (2010) Folate in Health and Disease , pp. 155-178
    • Wallis, D.1    Ballard, J.L.2    Shaw, G.M.3
  • 142
    • 0035826810 scopus 로고    scopus 로고
    • Vitamin B12 and folate in relation to the development of Alzheimer's disease
    • Wang H.-X., Wahlin A., Basun H., et al. Vitamin B12 and folate in relation to the development of Alzheimer's disease. Neurology 2001, 56:1188-1194.
    • (2001) Neurology , vol.56 , pp. 1188-1194
    • Wang, H.-X.1    Wahlin, A.2    Basun, H.3
  • 143
    • 0142198586 scopus 로고
    • Studies on the folic acid activity of human serum
    • Waters A.H., Mollin D.L. Studies on the folic acid activity of human serum. J Clin Pathol 1961, 14:335-344.
    • (1961) J Clin Pathol , vol.14 , pp. 335-344
    • Waters, A.H.1    Mollin, D.L.2
  • 144
    • 33745146118 scopus 로고    scopus 로고
    • Acquired and inherited disorders of cobalamin and folate in children
    • Whitehead V.M. Acquired and inherited disorders of cobalamin and folate in children. Br J Haematol 2006, 134:125-136.
    • (2006) Br J Haematol , vol.134 , pp. 125-136
    • Whitehead, V.M.1
  • 145
    • 39849101600 scopus 로고    scopus 로고
    • Characterisation of folate uptake by choroid plexus epithelial cells in a rat primary culture model
    • Wollack J.B., Makori B., Ahlawat S., et al. Characterisation of folate uptake by choroid plexus epithelial cells in a rat primary culture model. J Neurochem 2008, 104:1494-1503.
    • (2008) J Neurochem , vol.104 , pp. 1494-1503
    • Wollack, J.B.1    Makori, B.2    Ahlawat, S.3
  • 146
    • 26844482711 scopus 로고
    • The nervous symptoms in pernicious anaemia: an analysis of 150 cases
    • Woltmann H.W. The nervous symptoms in pernicious anaemia: an analysis of 150 cases. Am J Med Sci 1919, 157:400-409.
    • (1919) Am J Med Sci , vol.157 , pp. 400-409
    • Woltmann, H.W.1


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