Invariant natural killer T cells in children with eosinophilic esophagitis

Clinical and Experimental Allergy

Volumn 44, Issue 1, 2014, Pages 58-68

  Jyonouchi, S ^a   Smith, C L ^a   Saretta, F ^b   Abraham, V ^a   Ruymann, K R ^a   Modayur Chandramouleeswaran, P ^a   Wang, M L ^a   Spergel, J M ^a   Cianferoni, A ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF UDINE   (Italy)

Author keywords

Eosinophilic esophagitis; Invariant natural killer T cells; Sphingolipids

Indexed keywords

ALPHA GALACTOSYLCERAMIDE; CD1D ANTIGEN; CHEMOKINE RECEPTOR; CYTOKINE; IMMUNOGLOBULIN E; INTERLEUKIN 13; RANTES; SPHINGOLIPID; TOLL LIKE RECEPTOR 3;

ARTICLE; CELL FUNCTION; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; EOSINOPHILIC ESOPHAGITIS; ESOPHAGUS BIOPSY; FEMALE; FOOD ALLERGY; HUMAN; MALE; MILK; NATURAL KILLER T CELL; PATHOGENESIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCHOOL CHILD;

EOSINOPHILIC ESOPHAGITIS; INVARIANT NATURAL KILLER T CELLS; SPHINGOLIPIDS;

ADOLESCENT; ALLERGENS; ANIMALS; CHILD; CHILD, PRESCHOOL; CYTOKINES; EOSINOPHILIC ESOPHAGITIS; FEMALE; HUMANS; IMMUNOPHENOTYPING; LYMPHOCYTE COUNT; MALE; MILK; NATURAL KILLER T-CELLS; PHENOTYPE; RECEPTORS, CCR3; RECEPTORS, CCR4; RECEPTORS, CCR5; TH2 CELLS;

EID: 84890828260     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/cea.12201     Document Type: Article

References (50)

1. Noel RJ, Rothenberg ME. Eosinophilic esophagitis. Curr Opin Pediatr 2005; 17:690-4.
2. Straumann A, Simon HU. Eosinophilic esophagitis: escalating epidemiology? J Allergy Clin Immunol 2005; 115:418-9.
3. Liacouras CA, Spergel JM, Ruchelli E et al. Eosinophilic esophagitis: a 10-year experience in 381 children. Clin Gastroenterol Hepatol 2005; 3:1198-206.
4. Blanchard C, Wang N, Rothenberg ME. Eosinophilic esophagitis: pathogenesis, genetics, and therapy. J Allergy Clin Immunol 2006; 118:1054-9.
5. Spergel JM, Andrews T, Brown-Whitehorn TF, Beausoleil JL, Liacouras CA. Treatment of eosinophilic esophagitis with specific food elimination diet directed by a combination of skin prick and patch tests. Ann Allergy Asthma Immunol 2005; 95:336-43.
6. Markowitz JE, Spergel JM, Ruchelli E, Liacouras CA. Elemental diet is an effective treatment for eosinophilic esophagitis in children and adolescents. Am J Gastroenterol 2003; 98:777-82.
7. Spergel JM, Beausoleil JL, Mascarenhas M, Liacouras CA. The use of skin prick tests and patch tests to identify causative foods in eosinophilic esophagitis. J Allergy Clin Immunol 2002; 109:363-8.
8. Spergel JM, Brown-Whitehorn T, Beausoleil JL, Shuker M, Liacouras CA. Predictive values for skin prick test and atopy patch test for eosinophilic esophagitis. J Allergy Clin Immunol 2007; 119:509-11.
9. Rothenberg ME, Spergel JM, Sherrill JD et al. Common variants at 5q22 associate with pediatric eosinophilic esophagitis. Nat Genet 2010; 42:289-91.
10. Sherrill JD, Gao PS, Stucke EM et al. Variants of thymic stromal lymphopoietin and its receptor associate with eosinophilic esophagitis. J Allergy Clin Immunol 1990; 126:160-5 e3.
11. Berin MC, Shreffler WG. T(H)2 adjuvants: implications for food allergy. J Allergy Clin Immunol 2008; 121:1311-20.
12. Oki S, Tomi C, Yamamura T, Miyake S. Preferential T(h)2 polarization by OCH is supported by incompetent NKT cell induction of CD40L and following production of inflammatory cytokines by bystander cells in vivo. Int Immunol 2005; 17:1619-29.
13. Kim JO, Kim DH, Chang WS et al. Asthma is induced by intranasal coadministration of allergen and natural killer T-cell ligand in a mouse model. J Allergy Clin Immunol 2004; 114:1332-8.
14. Bendelac A, Hunziker RD, Lantz O. Increased interleukin 4 and immunoglobulin E production in transgenic mice overexpressing NK1 T cells. J Exp Med 1996; 184:1285-93.
15. Jyonouchi S, Abraham V, Orange JS et al. Invariant natural killer T cells from children with versus without food allergy exhibit differential responsiveness to milk-derived sphingomyelin. J Allergy Clin Immunol. [Research Support, N.I.H., Extramural]. 2011; 128:102-9.
16. Rajavelu P, Rayapudi M, Moffitt M, Mishra A. Significance of para-esophageal lymph nodes in food or aeroallergen-induced iNKT cell-mediated experimental eosinophilic esophagitis. Am J Physiol Gastrointest Liver Physiol 2012; 302:G645-54.
17. Liacouras CA, Furuta GT, Hirano I et al. Eosinophilic esophagitis: updated consensus recommendations for children and adults. J Allergy Clin Immunol. [Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Review]. 2011; 128:3-20. e6.
18. Liacouras CA, Wenner WJ, Brown K, Ruchelli E. Primary eosinophilic esophagitis in children: successful treatment with oral corticosteroids. J Pediatr Gastroenterol Nutr 1998; 26:380-5.
19. Ruchelli E, Wenner W, Voytek T, Brown K, Liacouras C. Severity of esophageal eosinophilia predicts response to conventional gastroesophageal reflux therapy. Pediatr Dev Pathol 1999; 2:15-8.
20. Sant'Anna AM, Rolland S, Fournet JC, Yazbeck S, Drouin E. Eosinophilic esophagitis in children: symptoms, histology and pH probe results. J Pediatr Gastroenterol Nutr 2004; 39:373-7.
21. Gumperz JE, Miyake S, Yamamura T, Brenner MB. Functionally distinct subsets of CD1d-restricted natural killer T cells revealed by CD1d tetramer staining. J Exp Med 2002; 195:625-36.
22. Sakuishi K, Oki S, Araki M, Porcelli SA, Miyake S, Yamamura T. Invariant NKT cells biased for IL-5 production act as crucial regulators of inflammation. J Immunol 2007; 179:3452-62.
23. Bendelac A, Savage PB, Teyton L. The biology of NKT cells. Annu Rev Immunol 2007; 25:297-336.
24. Cohen NR, Garg S, Brenner MB. Antigen Presentation by CD1 Lipids, T Cells, and NKT Cells in Microbial Immunity. Adv Immunol 2009; 102:1-94.
25. Lee PT, Putnam A, Benlagha K, Teyton L, Gottlieb PA, Bendelac A. Testing the NKT cell hypothesis of human IDDM pathogenesis. J Clin Invest 2002; 110:793-800.
26. + NKT cells derived from multiple sclerosis in remission. Int Immunol 2003; 15:279-88.
27. Marsh RA, Villanueva J, Kim MO et al. Patients with X-linked lymphoproliferative disease due to BIRC4 mutation have normal invariant natural killer T-cell populations. Clin Immunol 2009; 132:116-23.
28. Kim CH, Butcher EC, Johnston B. Distinct subsets of human Valpha24-invariant NKT cells: cytokine responses and chemokine receptor expression. Trends Immunol 2002; 23:516-9.
29. Thomas SY, Hou R, Boyson JE et al. CD1d-restricted NKT cells express a chemokine receptor profile indicative of Th1-type inflammatory homing cells. J Immunol 2003; 171:2571-80.
30. Sherrill JD, Gao PS, Stucke EM et al. Variants of thymic stromal lymphopoietin and its receptor associate with eosinophilic esophagitis. J Allergy Clin Immunol 2010; 126:160-5.
31. Bennett LD, Fox JM, Signoret N. Mechanisms regulating chemokine receptor activity. Immunology 2011; 134:246-56.
32. Akbari O, Stock P, Meyer E et al. Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity. Nat Med 2003; 9:582-8.
33. Taniguchi M, Harada M, Kojo S, Nakayama T, Wakao H. The regulatory role of Valpha14 NKT cells in innate and acquired immune response. Annu Rev Immunol 2003; 21:483-513.
34. Tupin E, Nicoletti A, Elhage R et al. CD1d-dependent activation of NKT cells aggravates atherosclerosis. J Exp Med 2004; 199:417-22.
35. Lisbonne M, Diem S, de Castro Keller A et al. Cutting edge: invariant V alpha 14 NKT cells are required for allergen-induced airway inflammation and hyperreactivity in an experimental asthma model. J Immunol 2003; 15:171:1637-41.
36. Thomas SY, Lilly CM, Luster AD. Invariant natural killer T cells in bronchial asthma. N Engl J Med 2006; 15:354; author reply -6.
37. Blanchard C, Wang N, Stringer KF et al. Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis. J Clin Invest. 2006; 116:536-47.
38. Gupta SK, Fitzgerald JF, Kondratyuk T, HogenEsch H. Cytokine expression in normal and inflamed esophageal mucosa: a study into the pathogenesis of allergic eosinophilic esophagitis. J Pediatr Gastroenterol Nutr 2006; 42:22-6.
39. Altomare A, Ma J, Guarino MP et al. Platelet-activating factor and distinct chemokines are elevated in mucosal biopsies of erosive compared with non-erosive reflux disease patients and controls. Neurogastroenterol Motil 2012; 24:943-e463.
40. Groger M, Klemens C, Wendt S et al. Mediators and cytokines in persistent allergic rhinitis and nonallergic rhinitis with eosinophilia syndrome. Int Arch Allergy Immunol 2012; 159:171-8.
41. Berra B, Colombo I, Sottocornola E, Giacosa A. Dietary sphingolipids in colorectal cancer prevention. Eur J Cancer Prev 2002; 11:193-7.
42. Blanpain C, Buser R, Power CA et al. A chimeric MIP-1alpha/RANTES protein demonstrates the use of different regions of the RANTES protein to bind and activate its receptors. J Leukoc Biol 2001; 69:977-85.
43. Wu WH, Park CO, Oh SH et al. Thymic stromal lymphopoietin-activated invariant natural killer T cells trigger an innate allergic immune response in atopic dermatitis. J Allergy Clin Immunol. [Research Support, Non-U.S. Gov't]. 2010; 126:290-9, 9 e1-4.
44. + natural killer T cells in bronchial asthma. N Engl J Med 2006; 354:1117-29.
45. Wu DY, Segal NH, Sidobre S, Kronenberg M, Chapman PB. Cross-presentation of disialoganglioside GD3 to natural killer T cells. J Exp Med 2003; 198:173-81.
46. Sriram V, Du W, Gervay-Hague J, Brutkiewicz RR. Cell wall glycosphingolipids of Sphingomonas paucimobilis are CD1d-specific ligands for NKT cells. Eur J Immunol 2005; 35:1692-701.
47. Fischer K, Scotet E, Niemeyer M et al. Mycobacterial phosphatidylinositol mannoside is a natural antigen for CD1d-restricted T cells. Proc Natl Acad Sci U S A 2004; 101:10685-90.
48. Huwiler A, Kolter T, Pfeilschifter J, Sandhoff K. Physiology and pathophysiology of sphingolipid metabolism and signaling. Biochim Biophys Acta 2000; 1485:63-99.
49. Sampson HA. Update on food allergy. J Allergy Clin Immunol 2004; 113:805-19.
50. Kagalwalla AF, Shah A, Li BU et al. Identification of specific foods responsible for inflammation in children with eosinophilic esophagitis successfully treated with empiric elimination diet. J Pediatr Gastroenterol Nutr. [Comment]. 2011; 53:145-9.