-
1
-
-
0032560850
-
The structural basis of the activation of Ras by Sos
-
Boriack-Sjodin PA, Margarit SM, Bar-Sagi D, Kuriyan J (1998) The structural basis of the activation of Ras by Sos. Nature 394(6691):337-343.
-
(1998)
Nature
, vol.394
, Issue.6691
, pp. 337-343
-
-
Boriack-Sjodin, P.A.1
Margarit, S.M.2
Bar-Sagi, D.3
Kuriyan, J.4
-
2
-
-
7044226349
-
Structural analysis of autoinhibition in the Ras activator Son of sevenless
-
Sondermann H, et al. (2004) Structural analysis of autoinhibition in the Ras activator Son of sevenless. Cell 119(3):393-405.
-
(2004)
Cell
, vol.119
, Issue.3
, pp. 393-405
-
-
Sondermann, H.1
-
3
-
-
0027931640
-
Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway
-
Aronheim A, et al. (1994) Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway. Cell 78(6):949-961.
-
(1994)
Cell
, vol.78
, Issue.6
, pp. 949-961
-
-
Aronheim, A.1
-
4
-
-
28044449725
-
Computational docking and solution x-Ray scattering predict a membrane-Interacting role for the histone domain of the Ras activator son of sevenless
-
Sondermann H, Nagar B, Bar-Sagi D, Kuriyan J (2005) Computational docking and solution x-Ray scattering predict a membrane-Interacting role for the histone domain of the Ras activator son of sevenless. Proc Natl Acad Sci USA 102(46): 16632-16637.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.46
, pp. 16632-16637
-
-
Sondermann, H.1
Nagar, B.2
Bar-Sagi, D.3
Kuriyan, J.4
-
5
-
-
43249100633
-
Membrane-Dependent signal integration by the Ras activator Son of sevenless
-
Gureasko J, et al. (2008) Membrane-Dependent signal integration by the Ras activator Son of sevenless. Nat Struct Mol Biol 15(5):452-461.
-
(2008)
Nat Struct Mol Biol
, vol.15
, Issue.5
, pp. 452-461
-
-
Gureasko, J.1
-
6
-
-
77649241353
-
Role of the histone domain in the autoinhibition and activation of the Ras activator Son of Sevenless
-
Gureasko J, et al. (2010) Role of the histone domain in the autoinhibition and activation of the Ras activator Son of Sevenless. Proc Natl Acad Sci USA 107(8):3430-3435.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.8
, pp. 3430-3435
-
-
Gureasko, J.1
-
7
-
-
77649264378
-
Allosteric gating of Son of sevenless activity by the histone domain
-
Yadav KK, Bar-Sagi D (2010) Allosteric gating of Son of sevenless activity by the histone domain. Proc Natl Acad Sci USA 107(8):3436-3440.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.8
, pp. 3436-3440
-
-
Yadav, K.K.1
Bar-Sagi, D.2
-
8
-
-
34447568476
-
Phospholipase D2-Generated phosphatidic acid couples EGFR stimulation to Ras activation by Sos
-
Zhao C, Du G, Skowronek K, Frohman MA, Bar-Sagi D (2007) Phospholipase D2-Generated phosphatidic acid couples EGFR stimulation to Ras activation by Sos. Nat Cell Biol 9(6):706-712.
-
(2007)
Nat Cell Biol
, vol.9
, Issue.6
, pp. 706-712
-
-
Zhao, C.1
Du, G.2
Skowronek, K.3
Frohman, M.A.4
Bar-Sagi, D.5
-
9
-
-
81455125472
-
Activation of Ras requires the ERM-Dependent link of actin to the plasma membrane
-
Sperka T, et al. (2011) Activation of Ras requires the ERM-Dependent link of actin to the plasma membrane. PLoS ONE 6(11):e27511.
-
(2011)
PLoS ONE
, vol.6
, Issue.11
-
-
Sperka, T.1
-
10
-
-
0031081475
-
ERM proteins: Head-To-Tail regulation of actin-Plasma membrane interaction
-
Tsukita S, Yonemura S, Tsukita S (1997) ERM proteins: Head-To-Tail regulation of actin-Plasma membrane interaction. Trends Biochem Sci 22(2):53-58.
-
(1997)
Trends Biochem Sci
, vol.22
, Issue.2
, pp. 53-58
-
-
Tsukita, S.1
Yonemura, S.2
Tsukita, S.3
-
11
-
-
0032559362
-
Rho GTPases and the actin cytoskeleton
-
Hall A (1998) Rho GTPases and the actin cytoskeleton. Science 279(5350):509-514.
-
(1998)
Science
, vol.279
, Issue.5350
, pp. 509-514
-
-
Hall, A.1
-
12
-
-
0344885558
-
Structural evidence for feedback activation by Ras.GTP of the Ras-Specific nucleotide exchange factor SOS
-
Margarit SM, et al. (2003) Structural evidence for feedback activation by Ras.GTP of the Ras-Specific nucleotide exchange factor SOS. Cell 112(5):685-695.
-
(2003)
Cell
, vol.112
, Issue.5
, pp. 685-695
-
-
Margarit, S.M.1
-
13
-
-
0028795913
-
Quantitative analysis of the complex between p21ras and the Ras-Binding domain of the human Raf-1 protein kinase
-
Herrmann C, Martin GA, Wittinghofer A (1995) Quantitative analysis of the complex between p21ras and the Ras-Binding domain of the human Raf-1 protein kinase. J Biol Chem 270(7):2901-2905.
-
(1995)
J Biol Chem
, vol.270
, Issue.7
, pp. 2901-2905
-
-
Herrmann, C.1
Martin, G.A.2
Wittinghofer, A.3
-
14
-
-
33845900943
-
Germline gain-Of-Function mutations in SOS1 cause Noonan syndrome
-
Roberts AE, et al. (2007) Germline gain-Of-Function mutations in SOS1 cause Noonan syndrome. Nat Genet 39(1):70-74.
-
(2007)
Nat Genet
, vol.39
, Issue.1
, pp. 70-74
-
-
Roberts, A.E.1
-
15
-
-
33845884026
-
Gain-Of-Function SOS1 mutations cause a distinctive form of Noonan syndrome
-
Tartaglia M, et al. (2007) Gain-Of-Function SOS1 mutations cause a distinctive form of Noonan syndrome. Nat Genet 39(1):75-79.
-
(2007)
Nat Genet
, vol.39
, Issue.1
, pp. 75-79
-
-
Tartaglia, M.1
-
16
-
-
33751102674
-
Regulation of ras signaling dynamics by Sos-Mediated positive feedback
-
Boykevisch S, et al. (2006) Regulation of ras signaling dynamics by Sos-Mediated positive feedback. Curr Biol 16(21):2173-2179.
-
(2006)
Curr Biol
, vol.16
, Issue.21
, pp. 2173-2179
-
-
Boykevisch, S.1
-
17
-
-
0035871299
-
The NF2 tumor suppressor gene product, merlin, mediates contact inhibition of growth through interactions with CD44
-
Morrison H, et al. (2001) The NF2 tumor suppressor gene product, merlin, mediates contact inhibition of growth through interactions with CD44. Genes Dev 15(8):968-980.
-
(2001)
Genes Dev
, vol.15
, Issue.8
, pp. 968-980
-
-
Morrison, H.1
-
18
-
-
33846702026
-
Merlin/neurofibromatosis type 2 suppresses growth by inhibiting the activation of Ras and Rac
-
Morrison H, et al. (2007) Merlin/neurofibromatosis type 2 suppresses growth by inhibiting the activation of Ras and Rac. Cancer Res 67(2):520-527.
-
(2007)
Cancer Res
, vol.67
, Issue.2
, pp. 520-527
-
-
Morrison, H.1
-
20
-
-
0035866335
-
Gene expression patterns associated with the metastatic phenotype in rodent and human tumors
-
Nestl A, et al. (2001) Gene expression patterns associated with the metastatic phenotype in rodent and human tumors. Cancer Res 61(4):1569-1577.
-
(2001)
Cancer Res
, vol.61
, Issue.4
, pp. 1569-1577
-
-
Nestl, A.1
-
21
-
-
2342477964
-
Ezrin, a key component in tumor metastasis
-
Hunter KW (2004) Ezrin, a key component in tumor metastasis. Trends Mol Med 10(5): 201-204.
-
(2004)
Trends Mol Med
, vol.10
, Issue.5
, pp. 201-204
-
-
Hunter, K.W.1
-
22
-
-
72749098126
-
Concomitant suppression of three target genes can explain the impact of a microRNA on metastasis
-
Valastyan S, Benaich N, Chang A, Reinhardt F, Weinberg RA (2009) Concomitant suppression of three target genes can explain the impact of a microRNA on metastasis. Genes Dev 23(22):2592-2597.
-
(2009)
Genes Dev
, vol.23
, Issue.22
, pp. 2592-2597
-
-
Valastyan, S.1
Benaich, N.2
Chang, A.3
Reinhardt, F.4
Weinberg, R.A.5
-
23
-
-
77954725226
-
Moesin-Dependent cytoskeleton remodelling is associated with an anaplastic phenotype of pancreatic cancer
-
Abiatari I, et al. (2010) Moesin-Dependent cytoskeleton remodelling is associated with an anaplastic phenotype of pancreatic cancer. J Cell Mol Med 14(5):1166-1179.
-
(2010)
J Cell Mol Med
, vol.14
, Issue.5
, pp. 1166-1179
-
-
Abiatari, I.1
-
24
-
-
0038284829
-
Established and emerging fluorescence-Based assays for G-Protein function: Ras-Superfamily GTPases
-
Rojas RJ, Kimple RJ, Rossman KL, Siderovski DP, Sondek J (2003) Established and emerging fluorescence-Based assays for G-Protein function: Ras-Superfamily GTPases. Comb Chem High Throughput Screen 6(4):409-418.
-
(2003)
Comb Chem High Throughput Screen
, vol.6
, Issue.4
, pp. 409-418
-
-
Rojas, R.J.1
Kimple, R.J.2
Rossman, K.L.3
Siderovski, D.P.4
Sondek, J.5
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