Low paternal dietary folate alters the mouse sperm epigenome and is associated with negative pregnancy outcomes

Nature Communications

Volumn 4, Issue , 2013, Pages

  Lambrot, R ^a   Xu, C ^a   Saint Phar, S ^a   Chountalos, G ^a   Cohen, T ^a   Paquet, M ^b   Suderman, M ^c   Hallett, M ^c   Kimmins, S ^a,d  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c MCGILL UNIVERSITY   (Canada)

^d MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN; CHOLECYSTOKININ A RECEPTOR; CYTOCHROME P450 2E1; FOLIC ACID; GLUCURONOSYLTRANSFERASE 1A1; GLUCURONOSYLTRANSFERASE 1A9; HERMES ANTIGEN; HISTONE H3; LEUCINE RICH REPEAT KINASE 2; NUCLEAR RECEPTOR NR4A3; PROTEIN BCL 2; TRANSCRIPTION FACTOR CLOCK; TRANSCRIPTION FACTOR NKX2.2;

DIET; DNA; GENETIC ANALYSIS; GENETIC DRIFT; GENOME; HEALTH CARE; PATERNAL EFFECT; PREGNANCY; SPERM;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; BIRTH DEFECT; CONTROLLED STUDY; DIET THERAPY; DIETARY INTAKE; DNA DAMAGE; DNA METHYLATION; FEMALE; FETUS; FOLIC ACID DEFICIENCY; GENE EXPRESSION; HISTONE METHYLATION; INSULIN DEPENDENT DIABETES MELLITUS; LEYDIG CELL; MALE; MALE FERTILITY; MEIOSIS; MENTAL DISEASE; MOUSE; NEOPLASM; NEUROLOGIC DISEASE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NUTRITION; PATERNAL NUTRITION; PLACENTA; PREGNANCY OUTCOME; PROGENY; REPRODUCTIVE SUCCESS; SOMATIC CELL; SPERM; SPERMATOCYTE; SPERMATOGENESIS; SPERMATOZOON COUNT; TRANSCRIPTION INITIATION SITE;

MUS;

ANIMALS; DIET; DNA DAMAGE; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; FOLIC ACID; FOLIC ACID DEFICIENCY; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HISTONES; MALE; MEIOSIS; MICE; MICE, INBRED C57BL; PLACENTA; PREGNANCY; PREGNANCY OUTCOME; SPERMATOCYTES; SPERMATOZOA;

EID: 84890766312     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms3889     Document Type: Article

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