Erythropoietin-mediated protection of insect brain neurons involves JAK and STAT but not PI3K transduction pathways

Neuroscience

Volumn 258, Issue , 2014, Pages 218-227

  Miljus, N ^a   Heibeck, S ^a   Jarrar, M ^a   Micke, M ^a   Ostrowski, D ^a,b   Ehrenreich, H ^c,d   Heinrich, R ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b UNIVERSITY OF MISSOURI   (United States)

^c MAX PLANCK INSTITUTE OF EXPERIMENTAL MEDICINE   (Germany)

^d Deutsche Forschungsgemeinschaft   (Germany)

Author keywords

Apoptosis; H 7; Hypoxia; Insect; Locusta migratoria; Primary brain cell culture

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; 2 MORPHOLINO 8 PHENYLCHROMONE; ERYTHROPOIETIN; ERYTHROPOIETIN RECEPTOR; JANUS KINASE; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN INHIBITOR; RECOMBINANT ERYTHROPOIETIN; STAT PROTEIN;

ACRIDIDAE; ANIMAL CELL; APOPTOSIS; ARTICLE; BRAIN NERVE CELL; CELL HYPOXIA; CONTROLLED STUDY; ENZYME INHIBITION; NERVE CELL CULTURE; NERVE CELL NECROSIS; NERVE REGENERATION; NEUROPROTECTION; NONHUMAN; PRIMARY CULTURE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

APOPTOSIS; EPO; EPO RECEPTOR; EPOR; ERYTHROPOIETIN; GENTAMICIN; GM; H-7; HYPOXIA; INSECT; JAK2; JANUS KINASE 2; LOCUSTA MIGRATORIA; MAPK; MITOGEN-ACTIVATED PROTEIN KINASE; PBS; PHOSPHATE-BUFFERED SALINE; PHOSPHOINOSITOL-3-KINASE; PHOSPHOINOSITOL-3-KINASE/PROTEIN KINASE B; PI3K; PI3K/AKT; PRIMARY BRAIN CELL CULTURE; RECOMBINANT HUMAN EPO; RHEPO; ROOM TEMPERATURE; RT; SIGNAL TRANSDUCERS AND ACTIVATORS OF TRANSCRIPTION; STAT; Β COMMON RECEPTOR; ΒC-R;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ANIMALS; ANOXIA; APOPTOSIS; BRAIN; CELL SURVIVAL; CELLS, CULTURED; CHROMONES; ENZYME INHIBITORS; ERYTHROPOIETIN; GRASSHOPPERS; HUMANS; INSECT PROTEINS; JANUS KINASE 2; MORPHOLINES; NEURONS; NEUROPROTECTIVE AGENTS; PHOSPHATIDYLINOSITOL 3-KINASES; SIGNAL TRANSDUCTION; STAT TRANSCRIPTION FACTORS; TYRPHOSTINS;

EID: 84890665681     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2013.11.020     Document Type: Article

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