1-(5-Isoquinolinesulfonyl)-2-methylpiperazine induces apoptosis in human neuroblastoma cells, SH-SY5Y, through a p53-dependent pathway

Journal of Biological Chemistry

Volumn 272, Issue 7, 1997, Pages 4252-4260

  Ronca, Francesca ^a   Chan, Shing Leng ^a   Yu, Victor C ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; FASUDIL; ISOQUINOLINE DERIVATIVE; MONOCLONAL ANTIBODY; N (2 GUANIDINOETHYL) 5 ISOQUINOLINESULFONAMIDE; PROTEIN P53; STAUROSPORINE;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; GENE MUTATION; HUMAN; HUMAN CELL; NEUROBLASTOMA CELL; PRIORITY JOURNAL; TUMOR CELL LINE; TUMOR SUPPRESSOR GENE;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; APOPTOSIS; CELL NUCLEUS; ENZYME INHIBITORS; HALF-LIFE; HUMANS; MUTATION; NEUROBLASTOMA; PROTEIN KINASE INHIBITORS; STAUROSPORINE; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0031047966     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.7.4252     Document Type: Article

References (62)

1. Wyllie, A. H., Kerr, J. F., and Currie, A. R. (1980) Int. Rev. Cytol 68, 251-306
2. Donehower, L. A., Harvey, M., Slagle, B. L., McArthur, M. J., Montgomery, C. A., Jr., Butel, J. S., and Bradley, A. (1992) Nature 356, 215-221
3. Yonish-Rouach, E., Resnitzky, D., Lotem, J., Sachs, L., Kimchi, A., and Oren, M. (1991) Nature 352, 345-347
4. Harper, J. W., Adami, G. R., Wei, N., Keyomarsi, K., and Elledge, S. J. (1993) Cell 75, 805-816
5. El-Deiry, W. S., Tokino, T., Velculescu, V. E., Levy, D. B., Parsons, R., Trent, J. M., Lin, D., Mercer, W. E., Kinzler, K. W., and Vogelstein, B. (1993) Cell 75, 817-825
6. Xiong, Y., Hannon, G. J., Zhang, H., Casso, D., Kobayashi, R., and Beach, D. (1993) Nature 366, 701-704
7. Shaw, P., Bovey, R., Tardy, S., Sahli, R., Sordat, B., and Costa, J. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 4495-4499
8. Vogelstein, B. (1990) Nature 348, 681-682
9. Hollstein, M., Sidransky, D., Vogelstein, B., and Harris, C. C. (1991) Science 253, 49-53
10. Miyashita, T., and Reed, J. C. (1995) Cell 80, 293-299
11. Owen-Schaub, L. B., Zhang, W., Cusack, J. C., Angelo, L. S., Santee, S. M., Fujiwara, T., Roth, J. A., Deisseroth, A. B., Zhang, W. W., and Kruzel, E. (1995) Mol. Cell. Biol. 1555, 3032-3040
12. Caelles, C., Helmberg, A., and Karin, M. (1994) Nature 370, 220-223
13. Ross, R. A., and Biedler, J. L. (1985) Cancer Res. 45, 1628-1632
14. Sádee, W., Yu, V. C., Richards, M. L., Preis, P. N., Schwab, M. R., Brodsky, F. M., and Biedler, J. L. (1987) Cancer Res. 47, 5207-5212
15. Vogan, K., Bernstein, M., Leclerc, J. M., Brisson, L., Brossard, J., Brodeur, G. M., Pelletier, J., and Gros, P. (1993) Cancer Res. 53, 5269-5273
16. Komuro, H., Hayashi, Y., Kawamura, M., Hayashi, K., Kaneko, Y., Kamoshita, S., Hanada, R., Yamamoto, K., Hongo, T., and Yamada, M. (1993) Cancer Res. 53, 5284-5288
17. Imamura, J., Bartram, C. R., Berthold, F., Harms, D., Nakamura, H., and Koeffler, H. P. (1993) Cancer Res. 53, 4053-4058
18. Hosoi, G., Hara, J., Okamura, T., Osugi, Y., Ishihara, S., Fukuzawa, M., Okada, A., Okada, S., and Tawa, A. (1994) Cancer 73, 3087-3093
19. Davidoff, A. M., Pence, J. C., Shorter, N. A., Iglehart, J. D., and Marks, J. R. (1992) Oncogene 7, 127-133
20. Lee, S., Christakos, S., and Small, M. B. (1993) Curr. Opin. Cell Biol. 5, 286-291
21. Yu, V. C., Delsert, C., Andersen, B., Holloway, J. M., Devary, O. V., Naar, A. M., Kim, S. Y., Boutin, J.-M., Glass, C. K., and Rosenfeld, M. G, (1991) Cell 67, 1251-1266
22. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254
23. Hidaka, H., Inagaki, M., Kawamoto, S., and Sasaki, Y. (1984) Biochemistry 23, 5036-5041
24. Seto, M., Sasaki, Y., Sasaki, Y., and Hidaka, H. (1991) Eur. J. Pharmacol. 195, 267-272
25. Bertrand, R., Solary, E., O'Connor, P., Kohn, K. W., and Pommier, Y. (1994) Exp. Cell Res. 211, 314-321
26. Dole, M. G., Jasty, R., Cooper, M. J., Thompson, C. B., Nunez, G., and Castle, V. P. (1995) Cancer Res, 55, 2576-2582
27. Berridge, M. V., and Tan, A. S. (1993) Arch. Biochem. Biophys. 303, 474-482
28. Nigro, J. M., Baker, S. J., Preisinger, A. C., Jessup, J. M.,Hostetter, R.,Cleary, K., Bigner, S. H., Davidson, N., Baylin, S., and Devilee, P. (1989) Nature 342, 705-708
29. Hinds, P. W., Finlay, C. A., Quartin, R. S., Baker, S. J., Fearon, E. R., Vogelstein, B., and Levine, A. J. (1990) Cell Growth & Differ. 1, 571-580
30. Kraiss, S., Spiess, S., Reihsaus, E., and Montenarh, M. (1991) Exp. Cell Res. 192, 157-164
31. Chandar, N., Billig, B., McMaster, J., and Novak, J. (1992) Br. J. Cancer 65, 208-214
32. Rodrigues, N. R., Rowan, A., Smith, M. E., Kerr, I. B., Bodmer, W. F., Gannon, J. V., and Lane, D. P. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 7555-7559
33. Bartek, J., Iggo, R., Gannon, J., and Lane, D. P. (1990) Oncogene 5, 893-899
34. Negrini, M., Sabbioni, S., Haldar, S., Possati, L., Castagnoli, A., Corallini, A., Barbanti-Brodano, G., and Croce, C. M. (1994) Cancer Res. 54, 1818-1824
35. Johnson, P., Gray, D., Mowat, M., and Benchimol, S. (1991) Mol. Cell Biol. 11, 1-11
36. Yaginuma, Y., Yamashita, T., Takuma, N., Katayama, H., and Ishikawa, M. (1995) Br. J. Cancer 71, 9-12
37. Stratton, M. R., Moss, S., Warren, W., Patterson, H., Clark, J., Fisher, C., Fletcher, C. D., Ball, A., Thomas, M., and Gusterson, B. A. (1990) Oncogene 5, 1297-1301
38. Romano, J. W., Ehrhart, J. C., Duthu, A., Kim, C. M., Appella, E., and May, P. (1989) Oncogene 4, 1483-1488
39. Yu, V. C., Hochhaus, G., Chang, F. H., Richards, M. L., Bourne, H. R., and Sádee, W. (1988) J. Neurochem. 51, 1892-1899
40. Yu, V. C., Richards, M. L., and Sádee, W. (1986) J. Biol. Chem. 261, 1065-1070
41. Melino, G., Annicchiarico-Petruzzelli, M., Piredda, L., Candi, E., Gentile, V., Davies, P. J., and Piacentini, M. (1994) Mol. Cell. Biol. 14, 6584-6596
42. Shaulian, E., Haviv, I., Shaul, Y., and Oren, M. (1995) Oncogene 10, 671-680
43. Shaulian, E., Zauberman, A., Ginsberg, D., and Oren, M. (1992) Mol. Cell. Biol. 12, 5581-5592
44. Lowe, S. W. (1995) Curr. Opin. Oncol. 7, 547-553.
45. Moll, U. M., LaQuaglia, M., Benard, J., and Riou, G. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 4407-4411
46. Moll, U. M., Ostermeyer, A. G., Haladay, R., Winkfield, B., Frazier, M., and Zambetti, G. (1996) Mol. Cell. Biol. 16, 1126-1137
47. Fritsche, M., Haessler, C., and Brandner, G. (1993) Oncogene 8, 307-318
48. Sheikh, M. S., Li, X. S., Chen, J. C., Shao, Z. M., Ordonez, J. V., and Fontana J. A. (1994) Oncogene 9, 3407-3415
49. Lowe, S. W., Ruley, H. E., Jacks, T., and Housman, D. E. (1993) Cell 74, 957-967
50. Clarke, A. R., Purdie, C. A., Harrison, D. J., Morris, R. G., Bird, C. C., Hooper M. L., and Wyllie, A. H. (1993) Nature 362, 849-852
51. Gartenhaus, R. B., Wang, P., and Hoffmann, P. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 265-268
52. Felipo, V., Minana, M.-D., and Grisolia, S. (1990) J. Biol. Chem. 266, 9599-9601
53. Haupt, Y., Rowan, S., Shaulian, E., Vousden, K. H., and Oren, M. (1995) Genes Dev. 9, 2170-2183
54. Wagner, A. J., Kokontis, J. M., and Hay, N. (1994) Genes Dev. 8, 2817-2830
55. Shea, T. B., Cressman, C. M., Spencer, M. J., Beermann, M. L., and Nixon, R. A. (1995) J. Neurochem. 65, 517-527
56. Canman, C. E., Gilmer, T. M., Coutts, S. B., and Kastan, M. B. (1995) Genes Dev. 9, 600-611
57. Jarvis, W. D., Turner, A. J., Povirk, L. F., Traylor, R. S., and Grant, S. (1994) Cancer Res. 54, 1707-1714
58. Traganos, F., Ardelt, B., Halko, N., Bruno, S., and Darzynkiewicz, Z. (1992) Cancer Res. 52, 6200-6208
59. Ojeda, F., Guarda, M. I., Maldonado, C., Folch, H., and Diehl, H. (1992) Int. J. Radiat. Biol. 61, 663-667
60. Shao, H., Zhou, J., and Ewald, S. J. (1995) Cell Immunol. 164, 11-19
61. Wolf, D., and Rotter, V. (1985) Proc. Natl. Acad. Sci. U. S. A. 82, 790-794
62. Jeoung, D. I., Tang, B., and Sonenberg, M. (1995) Biochem. Biophys. Res. Commun. 214, 361-366