Erythropoietin and normal brain development: Receptor expression determines multi-tissue response

Neurodegenerative Diseases

Volumn 3, Issue 1-2, 2006, Pages 68-75

  Chen, Zhi Yong ^a   Warin, Renaud ^a   Noguchi, Constance Tom ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

Brain development; Erythropoiesis; Erythropoietin; Hypoxic stress

Indexed keywords

ERYTHROPOIETIN; ERYTHROPOIETIN RECEPTOR;

ANEMIA; APOPTOSIS; BRAIN DEVELOPMENT; BRAIN ISCHEMIA; CELL SURVIVAL; DEVELOPMENTAL DISORDER; EMBRYO MORTALITY; ERYTHROID CELL; ERYTHROPOIESIS; HORMONE RESPONSE; HUMAN; HYPOXIA; MULTITISSUE RESPONSE; MUSCLE STEM CELL; NERVE CELL; NERVE CELL CULTURE; NEURAL STEM CELL; NEUROPROTECTION; NONHUMAN; OXYGEN TENSION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVIEW; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; STEM CELL; STRESS; TISSUE DISTRIBUTION; TISSUE REACTION; VASCULAR ENDOTHELIUM;

ANIMALS; ANOXIA; BRAIN; ERYTHROPOIETIN; RECEPTORS, ERYTHROPOIETIN;

EID: 33646760649     PISSN: 16602854     EISSN: 16602862     Source Type: Journal    
DOI: 10.1159/000092096     Document Type: Review

References (21)

1. Koury MJ, Sawyer ST, Brandt SJ: New insights into erythropoiesis. Curr Opin Hematol 2002;9:93-100.
2. Marti HH: Erythropoietin and the hypoxic brain. J Exp Biol 2004;207:3233-3242.
3. Ogilvie M, Yu X, Nicolas-Metral V, Pulido SM, Liu C, Ruegg UT, Noguchi CT: Erythropoietin stimulates proliferation and interferes with differentiation of myoblasts. J Biol Chem 2000;275:39754-39761.
4. Anagnostou A, Liu Z, Steiner M, Chin K, Lee ES, Kessimian N, Noguchi CT: Erythropoietin receptor mRNA expression in human endothelial cells. Proc Natl Acad Sci USA 1994;91:3974-3978.
5. Beleslin-Cokic BB, Cokic VP, Yu X, Weksler BB, Schechter AN, Noguchi CT: Erythropoietin and hypoxia stimulate erythropoietin receptor and nitric oxide production by endothelial cells. Blood 2004;104:2073-2080.
6. Shingo T, Sorokan ST, Shimazaki T, Weiss S: Erythropoietin regulates the in vitro and in vivo production of neuronal progenitors by mammalian forebrain neural stem cells. J Neurosci 2001;21:9733-9743.
7. Yu X, Shacka JJ, Eells JB, Suarez-Quian C, Przygodzki RM, Beleslin-Cokic B, Lin CS, Nikodem VM, Hempstead B, Flanders KC, Costantini F, Noguchi CT: Erythropoietin receptor signalling is required for normal brain development. Development 2002;129:505-516.
8. Wu H, Liu X, Jaenisch R, Lodish HF: Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor. Cell 1995;83:59-67.
9. Noguchi CT, Bae KS, Chin K, Wada Y, Schechter AN, Hankins WD: Cloning of the human erythropoietin receptor gene. Blood 1991;78:2548-2556.
10. Chin K, Oda N, Shen K, Noguchi CT: Regulation of transcription of the human erythropoietin receptor gene by proteins binding to GATA-1 and Sp1 motifs. Nucleic Acids Res 1995;23:3041-3049.
11. Yu X, Lin CS, Costantini F, Noguchi CT: The human erythropoietin receptor gene rescues erythropoiesis and developmental defects in the erythropoietin receptor null mouse. Blood 2001;98:475-477.
12. Socolovsky M, Fallon AE, Lodish HF: The prolactin receptor rescues EpoR-/- erythroid progenitors and replaces EpoR in a synergistic interaction with c-kit. Blood 1998;92:1491-1496.
13. Kertesz N, Wu J, Chen TH, Sucov HM, Wu H: The role of erythropoietin in regulating angiogenesis. Dev Biol 2004;276:101-110.
14. Ruschitzka FT, Wenger RH, Stallmach T, Quaschning T, de Wit C, Wagner K, Labugger R, Kelm M, Noll G, Rulicke T, Shaw S, Lindberg RL, Rodenwaldt B, Lutz H, Bauer C, Luscher TF, Gassmann M: Nitric oxide prevents cardiovascular disease and determines survival in polyglobulic mice overexpressing erythropoietin. Proc Natl Acad Sci USA 2000;97:11609-11613.
15. Moon C, Krawczyk M, Ahn D, Ahmet I, Paik D, Lakatta EG, Talan MI: Erythropoietin reduces myocardial infarction and left ventricular functional decline after coronary artery ligation in rats. Proc Natl Acad Sci USA 2003;100:11612-11617.
16. Liu C, Shen K, Liu Z, Noguchi CT: Regulated human erythropoietin receptor expression in mouse brain. J Biol Chem 1997;272:32395-32400.
17. Liu ZY, Chin K, Noguchi CT: Tissue specific expression of human erythropoietin receptor in transgenic mice. Dev Biol 1994;166:159-169.
18. Suzuki N, Ohneda O, Takahashi S, Higuchi M, Mukai HY, Nakahata T, Imagawa S, Yamamoto M: Erythroid-specific expression of the erythropoietin receptor rescued its null mutant mice from lethality. Blood 2002;100:2279-2288.
19. Sakanaka M, Wen TC, Matsuda S, Masuda S, Morishita E, Nagao M, Sasaki R: In vivo evidence that erythropoietin protects neurons from ischemic damage. Proc Natl Acad Sci USA 1998;95:4635-4640.
20. Ehrenreich H, Hasselblatt M, Dembowski C, Cepek L, Lewczuk P, Stiefel M, Rustenbeck HH, Breiter N, Jacob S, Knerlich F, Bohn M, Poser W, Ruther E, Kochen M, Gefeller O, Gleiter C, Wessel TC, De Ryck M, Itri L, Prange H, Cerami A, Brines M, Siren AL: Erythropoietin therapy for acute stroke is both safe and beneficial. Mol Med 2002;8:495-505.
21. Brines M, Cerami A: Emerging biological roles for erythropoietin in the nervous system. Nat Rev Neurosci 2005;6:484-494.