The proton-activated receptor GPR4 modulates glucose homeostasis by increasing insulin sensitivity

Cellular Physiology and Biochemistry

Volumn 32, Issue 5, 2013, Pages 1403-1416

  Giudici, Luca ^a   Velic, Ana ^a,d   Daryadel, Arezoo ^a   Bettoni, Carla ^a   Mohebbi, Nilufar ^a,b   Suply, Thomas ^c   Seuwen, Klaus ^c   Ludwig, Marie Gabrielle ^c   Wagner, Carsten A ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^c NOVARTIS PHARMA AG   (Switzerland)

^d UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Glucose metabolism; GPR4; Insulin; Proton sensing receptor

Indexed keywords

G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 4; GLUCOSE; INSULIN; INTERLEUKIN 10; INTERLEUKIN 6; LEPTIN; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DIET INDUCED OBESITY; FEMALE; GENE EXPRESSION; GENOTYPE; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE METABOLISM; GLUCOSE TOLERANCE; GLUCOSE TOLERANCE TEST; INFLAMMATION; INSULIN SENSITIVITY; LIPID DIET; LIVER; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKELETAL MUSCLE; WHITE ADIPOSE TISSUE;

MUS;

ADIPOSE TISSUE, WHITE; AGING; ANIMALS; DIET, HIGH-FAT; GENE EXPRESSION REGULATION; GLUCOSE; GLUCOSE TOLERANCE TEST; HOMEOSTASIS; HYDROGEN-ION CONCENTRATION; INSULIN RESISTANCE; INTERLEUKIN-10; INTERLEUKIN-6; LIVER; MICE; MICE, KNOCKOUT; MUSCLE, SKELETAL; OBESITY; PPAR ALPHA; PROTEIN DISULFIDE-ISOMERASES; PROTONS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84890595314     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000356578     Document Type: Article

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