Methotrexate induces germ cell apoptosis and impairs spermatogenesis in a rat

Pediatric Surgery International

Volumn 29, Issue 2, 2013, Pages 179-184

  Sukhotnik, Igor ^a,b   Nativ, Omri ^a   Roitburt, Alex ^a   Bejar, Daniel ^a   Coran, Arnold G ^c   Mogilner, Jorge G ^b   Nativ, Ofer ^b  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^b BNAI ZION MEDICAL CENTER   (Israel)

^c UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Apoptosis; Germ cell; Methotrexate; Rat; Spermatogenesis

Indexed keywords

METHOTREXATE; PROTEIN BAX; PROTEIN BCL 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG EFFECT; GERM CELL; HISTOPATHOLOGY; MALE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; RAT; SPERMATOGENESIS; TESTIS; WESTERN BLOTTING;

ABORTIFACIENT AGENTS, NONSTEROIDAL; ANALYSIS OF VARIANCE; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; DISEASE MODELS, ANIMAL; IN SITU NICK-END LABELING; MALE; METHOTREXATE; RATS; RATS, SPRAGUE-DAWLEY; SPERMATOGENESIS; SPERMATOZOA;

EID: 84878364180     PISSN: 01790358     EISSN: 14379813     Source Type: Journal    
DOI: 10.1007/s00383-012-3197-0     Document Type: Article

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