A new approach on methamphetamine-induced hepatotoxicity: Involvement of mitochondrial dysfunction

Xenobiotica

Volumn 44, Issue 1, 2014, Pages 70-76

  Eskandari, Mohammad Reza ^a   Rahmati, Mokhtar ^a   Khajeamiri, Ali Reza ^b   Kobarfard, Farzad ^c   Noubarani, Maryam ^a   Heidari, Himan ^a  

^a ZANJAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b Police University   (Iran)

^c SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Hepatotoxicity; Liver injury; Methamphetamine; Mitochondrial dysfunction; Oxidative stress

Indexed keywords

ALPHA TOCOPHEROL SUCCINATE; ANTIOXIDANT; CARNITINE; CYCLOSPORIN; CYTOCHROME C; FRUCTOSE; GLUTATHIONE; GLUTATHIONE DISULFIDE; MANNITOL; METHAMPHETAMINE; REACTIVE OXYGEN METABOLITE; SCAVENGER; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TRIFLUOPERAZINE; XYLITOL; TRYPAN BLUE;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; CELL VIABILITY; CONFORMATION; CONTROLLED STUDY; CYTOLYSIS; CYTOSOL; CYTOTOXICITY; DRUG EFFECT; ENZYME RELEASE; LIPID PEROXIDATION; LIVER CELL DAMAGE; LIVER MITOCHONDRION; LIVER TOXICITY; MALE; MEMBRANE DAMAGE; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL TOXICITY; NONHUMAN; OXIDATIVE STRESS; RAT; ANALYSIS OF VARIANCE; ANIMAL; DRUG EFFECTS; LIVER CELL; METABOLISM; MITOCHONDRION; SPRAGUE DAWLEY RAT; TOXIC HEPATITIS; TOXICITY;

ANALYSIS OF VARIANCE; ANIMALS; DRUG-INDUCED LIVER INJURY; GLUTATHIONE; HEPATOCYTES; LIPID PEROXIDATION; MALE; METHAMPHETAMINE; MITOCHONDRIA; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; TRYPAN BLUE;

EID: 84890516970     PISSN: 00498254     EISSN: 13665928     Source Type: Journal    
DOI: 10.3109/00498254.2013.807958     Document Type: Article

References (43)

1. Albertson TE, Derlet RW, Van Hoozen BE. (1999). Methamphetamine and the expanding complications of amphetamines. West J Med 170: 214-19.
2. Andersson BS, Aw TY, Jones DP. (1987). Mitochondrial transmembrane potential and pH gradient during anoxia. Am J Physiol 252:C349-55.
3. Baba T, Yamada H, Oguri K, Yoshimura H. (1988). Participation of cytochrome P-450 isozymes in N-demethylation, N-hydroxylation and aromatic hydroxylation of methamphetamine. Xenobiotica 18:475-84.
4. Benzie IFF. (1996). Lipid peroxidation: a review of causes, consequences, measurement and dietary influences. Int J Food Sci Nutr 47: 233-61.
5. Borutaite V. (2010). Mitochondria as decision-makers in cell death. Environ Mol Mutagen 51:406-16.
6. Brecht ML, Lovinger K, Herbeck DM, Urada D. (2013). Patterns of treatment utilization and methamphetamine use during first 10 years after methamphetamine initiation. J Subst Abuse Treat 44:548-56.
7. Caldwell J, Dring LG, Williams RT. (1972). Metabolism of (14 C) methamphetamine in man, the guinea pig and the rat. Biochem J 129: 11-22.
8. Cole SP, Deeley RG. (2006). Transport of glutathione and glutathione conjugates by MRP1. Trends Pharmacol Sci 27:438-46.
9. Cruickshank CC, Dyer KR. (2009). A review of the clinical pharmacology of methamphetamine. Addiction 104:1085-99.
10. Dahshan A. (2009). Prenatal exposure to methamphetamine presenting as neonatal cholestasis. J Clin Gastroenterol 43:88-90.
11. Derlet RW, Heischober B. (1990). Methamphetamine stimulant of the 1990s? West J Med 153:625-8.
12. Dostalek M, Jurica J, Pistovcakova J, et al. (2007). Effect of methamphetamine on cytochrome P450 activity. Xenobiotica 37:1355-66.
13. Eskandari MR, Fard JK, Hosseini MJ, Pourahmad J. (2012). Glutathione mediated reductive activation and mitochondrial dysfunction play key roles in lithium induced oxidative stress and cytotoxicity in liver. Biometals 25:863-73.
14. Galati G, Teng S, Moridani MY, et al. (2000). Cancer chemoprevention and apoptosis mechanisms induced by dietary polyphenolics. Drug Metabol Drug Interact 17:311-49.
15. Gogvadze V, Orrenius S, Zhivotovsky B. (2006). Multiple pathways of cytochrome c release from mitochondria in apoptosis. Biochimica et Biophysica Acta 1757:639-47.
16. Hissin J, Hilf R. (1976). A fluorometric method for determination of oxidised and reduced glutathione in tissues. Anal Biochem 74:214-26.
17. Kamijo Y, Soma K, Nishida M, et al. (2002). Acute liver failure following intravenous methamphetamine. Vet Hum Toxicol 44:216-7.
18. Karch SB, Stephens BG, Ho CH. (1999). Methamphetamine-related deaths in San Francisco: demographic, pathologic, and toxicologic profiles. J Forensic Sci 44:359-68.
19. Keppler D. (1999). Export pumps for glutathione S-conjugates. Free Radic Biol Med 27:985-91.
20. Kipke MD, OConnor S, Palmer R, MacKenzie RG. (1995). Street youth in Los Angeles. Profile of a group at high risk for human immunodeficiency virus infection. Arch Pediatr Adolesc Med 149: 513-51.
21. Koriem KM, Abdelhamid AZ, Younes HF. (2013). Caffeic acid protects tissue antioxidants and DNA content in methamphetamine induced tissue toxicity in SD rats. Toxicol Mech Methods 23: 134-43.
22. Kushnareva Y, Newmeyer DD. (2010). Bioenergetics and cell death. Ann N Y Acad Sci 1201:50-7.
23. Kuwayama K, Tsujikawa K, Miyaguchi H, et al. (2009). Determination of 4-hydroxy-3-methoxymethamphetamine as a metabolite of methamphetamine in rats and human liver microsomes using gas chromatography-mass spectrometry and liquid chromatographytandem mass spectrometry. J Anal Toxicol 33:266-71
24. Lin LY, Di Stefano EW, Schmitz DA, et al. (1997). Oxidation of methamphetamine and methylenedioxymethamphetamine by CYP2D6. Drug Metab Dispos 25:1059-64.
25. Moldeus P, Hogberg J, Orrenius S. (1978). Isolation and use of liver cells. Meth Enzymol 52:60-71.
26. Mooney LJ, Glasner-Edwards S, Rawson RA, Ling W. (2009). Medical effects of methamphetamine use. In: Roll JM, Rawson RA, Ling W, et al., eds. Methamphetamine addiction: from basic science to treatment. New York: Guilford, 117-42.
27. Nakagawa T, Kaneko S. (2008). Neuropsychotoxicity of abused drugs: molecular and neural mechanisms of neuropsychotoxicity induced by methamphetamine, 3,4-methylenedioxymethamphetamine (ecstasy), and 5-methoxy-N,N-diisopropyltryptamine (foxy). J Pharmacol Sci 106:2-8.
28. OBrien PJ, Siraki AG. (2005). Accelerated cytotoxicity mechanism screening using drug metabolising enzyme modulators. Curr Drug Metab 6:101-9.
29. Orrenius S, Nicotera P, Zhivotovsky B. (2011). Cell death mechanisms and their implications in toxicology. Toxicol Sci 119:3-19.
30. Pompella A, Visvikis A, Paolicchi A, et al. (2003). The changing faces of glutathione, a cellular protagonist. Biochem Pharmacol 66:1499-503.
31. Pourahmad J, Eskandari MR, Daraei B. (2010a). A comparison of hepatocyte cytotoxic mechanisms for thallium (I) and thallium (III). Environ Toxicol 25:456-67.
32. Pourahmad J, Eskandari MR, Nosrati M, et al. (2010b). Involvement of mitochondrial/lysosomal toxic cross-talk in ecstasy induced liver toxicity under hyperthermic condition. Eur J Pharmacol 643:162-9.
33. Pourahmad J, Hosseini MJ, Eskandari MR, et al. (2010c). Mitochondrial/ lysosomal toxic cross-talk plays a key role in cisplatin nephrotoxicity. Xenobiotica 40:763-71.
34. Pourahmad J, OBrien PJ. (2000). A comparison of hepatocyte cytotoxic mechanisms for Cu2 and Cd2. Toxicology 143:263-73.
35. Roberts SM, Harbison RD, James RC. (1994). Methamphetamine potentiation of carbon tetrachloride hepatotoxicity in mice. J Pharmacol Exp Ther 271:1051-7.
36. Roberts SM, Harbison RD, James RC. (1995). Mechanistic studies on the potentiation of carbon tetrachloride hepatotoxicity by methamphetamine. Toxicology 97:49-57.
37. Smith MT, Thor H, Hartzell P, Orrenius S. (1982). The measurement of lipid peroxidation in isolated hepatocytes. Biochem Pharmacol 31: 19-26.
38. Tang W. (2007). Drug metabolite profiling and elucidation of drug-induced hepatotoxicity. Expert Opin Drug Metab Toxicol 3: 407-20.
39. United Nations Office on Drugs and Crime. (2007). World drug report volume 1. Analysis. Vienna: United Nations Office on Drugs and Crime.
40. Valko M, Leibfritz D, Moncol J, et al. (2007). Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem Cell Biol 39:44-84.
41. Volkow ND, Fowler JS, Wang GJ, et al. (2010). Distribution and pharmacokinetics of methamphetamine in the human body: clinical implications. PLoS One 5:e15269.
42. Yamada H, Baba T, Hirata Y, et al. (1984). Studies on N-demethylation of methamphetamine by liver microsomes of guinea-pigs and rats: the role of flavin-containing mono-oxygenase and cytochrome P-450 systems. Xenobiotica 14:861-6.
43. Yamamoto T, Takano R, Egashira T, Yamanaka Y. (1984). Metabolism of methamphetamine, amphetamine and p-hydroxymethamphetamine by rat-liver microsomal preparations in vitro. Xenobiotica 14:867-75.