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Volumn 33, Issue 5, 2009, Pages 266-271

Determination of 4-hydroxy-3-methoxymethamphetamine as a metabolite of methamphetamine in rats and human liver microsomes using gas chromatography-mass spectrometry and liquid chromatography-tandem mass spectrometry

Author keywords

[No Author keywords available]

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; 4 HYDROXY 3 METHOMETHAMPHETAMINE; AMPHETAMINE; METHAMPHETAMINE; UNCLASSIFIED DRUG;

EID: 68949130822     PISSN: 01464760     EISSN: 01464760     Source Type: Journal    
DOI: 10.1093/jat/33.5.266     Document Type: Article
Times cited : (5)

References (31)
  • 1
    • 85036845371 scopus 로고    scopus 로고
    • National Police Agency of Japan. National Police Agency of Japan, Tokyo, Japan
    • National Police Agency of Japan. DRUG 2008. National Police Agency of Japan, Tokyo, Japan, 2008.
    • (2008) DRUG 2008
  • 2
    • 0034882387 scopus 로고    scopus 로고
    • Methamphetamine neurotoxicity: Necrotic and apoptotic mechanisms and relevance to human abuse and treatment
    • C. Davidson, A.J. Gow, T.H. Lee, and E.H. Ellinwood. Methamphetamine neurotoxicity: necrotic and apoptotic mechanisms and relevance to human abuse and treatment. Brain Res. Rev. 36: 1-22 (2001).
    • (2001) Brain Res. Rev. , vol.36 , pp. 1-22
    • Davidson, C.1    Gow, A.J.2    Lee, T.H.3    Ellinwood, E.H.4
  • 3
    • 4644320720 scopus 로고    scopus 로고
    • The methamphetamine experience: A NIDA partnership
    • G.R. Hanson, K.S. Rau, and A.E. Fleckenstein. The methamphetamine experience: a NIDA partnership. Neuropharmacology 47: 92-100 (2004).
    • (2004) Neuropharmacology , vol.47 , pp. 92-100
    • Hanson, G.R.1    Rau, K.S.2    Fleckenstein, A.E.3
  • 4
    • 0031755421 scopus 로고    scopus 로고
    • Determination of common drugs of abuse in body fluids using one isolation procedure and liquid chromatography-atmospheric-pressure chemicalionization mass spectromery
    • M.J. Bogusz, R.D. Maier, K.D. Krüger, and U. Kohls. Determination of common drugs of abuse in body fluids using one isolation procedure and liquid chromatography-atmospheric-pressure chemicalionization mass spectromery. J. Anal. Toxicol. 22: 549-558 (1998).
    • (1998) J. Anal. Toxicol. , vol.22 , pp. 549-558
    • Bogusz, M.J.1    Maier, R.D.2    Krüger, K.D.3    Kohls, U.4
  • 5
    • 0034306515 scopus 로고    scopus 로고
    • Liquid chromatography-mass spectrometry as a routine method in forensic sciences: A proof of maturity
    • M.J. Bogusz.Liquid chromatography-mass spectrometry as a routine method in forensic sciences: a proof of maturity. J. Chromatogr. B 748: 3-19 (2000).
    • (2000) J. Chromatogr. B , vol.748 , pp. 3-19
    • Bogusz, M.J.1
  • 6
    • 0031010732 scopus 로고    scopus 로고
    • Metabolism of selegiline in humans. Identification, excretion, and stereochemistry of urine metabolites
    • H.S. Shin. Metabolism of selegiline in humans. Identification, excretion, and stereochemistry of urine metabolites. Drug Metab. Dispos. 25: 657-662 (1997).
    • (1997) Drug Metab. Dispos. , vol.25 , pp. 657-662
    • Shin, H.S.1
  • 7
    • 0035664224 scopus 로고    scopus 로고
    • The pharmacology and toxicology of "ecstasy" (MDMA) and related drugs
    • H. Kalant. The pharmacology and toxicology of "ecstasy" (MDMA) and related drugs. CMAJ 165: 917-928 (2001).
    • (2001) CMAJ , vol.165 , pp. 917-928
    • Kalant, H.1
  • 8
    • 0037651952 scopus 로고    scopus 로고
    • Methylenedioxymethamphetamine (MDMA, Ecstasy) neurotoxicity: Cellular and molecular mechanisms
    • J. Lyles and J.L. Cadet. Methylenedioxymethamphetamine (MDMA, Ecstasy) neurotoxicity: cellular and molecular mechanisms. Brain Res. Rev. 42: 155-168 (2003).
    • (2003) Brain Res. Rev. , vol.42 , pp. 155-168
    • Lyles, J.1    Cadet, J.L.2
  • 9
    • 0015378775 scopus 로고
    • Metabolism of (14C)methamphetamine in man, the guinea pig and the rat
    • J. Caldwell, L.G. Dring, and R.T. Williams. Metabolism of (14C)methamphetamine in man, the guinea pig and the rat. Biochem. J. 129: 11-22 (1972).
    • (1972) Biochem. J. , vol.129 , pp. 11-22
    • Caldwell, J.1    Dring, L.G.2    Williams, R.T.3
  • 10
    • 0036183351 scopus 로고    scopus 로고
    • The effect of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) and its metabolites on neurohypophysial hormone release from the isolated rat hypothalamus
    • M.L. Forsling, J.K. Fallon, D. Shah, G.S. Tilbrook, D.A. Cowan, A.T. Kicman, and A.J. Hutt. The effect of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) and its metabolites on neurohypophysial hormone release from the isolated rat hypothalamus. Br. J. Pharmacol. 135: 649-656 (2002).
    • (2002) Br. J. Pharmacol. , vol.135 , pp. 649-656
    • Forsling, M.L.1    Fallon, J.K.2    Shah, D.3    Tilbrook, G.S.4    Cowan, D.A.5    Kicman, A.T.6    Hutt, A.J.7
  • 13
    • 0029846521 scopus 로고    scopus 로고
    • Analysis of 3,4-methylenedioxymethamphetamine (MDMA) and its metabolites in plasma and urine by HPLC-DAD and GC-MS
    • H. Helmlin, K. Bracher, D. Bourquin, D. Vonlanthen, R. Brenneisen, and J. Styk. Analysis of 3,4-methylenedioxymethamphetamine (MDMA) and its metabolites in plasma and urine by HPLC-DAD and GC-MS. J. Anal. Toxicol. 20: 432-440 (1996).
    • (1996) J. Anal. Toxicol. , vol.20 , pp. 432-440
    • Helmlin, H.1    Bracher, K.2    Bourquin, D.3    Vonlanthen, D.4    Brenneisen, R.5    Styk, J.6
  • 15
    • 21144458319 scopus 로고    scopus 로고
    • High-performance liquid chromatographic analysis of drugs of abuse in biologic samples
    • K. Nakashima. High-performance liquid chromatographic analysis of drugs of abuse in biologic samples J. Health Sci. 51: 272-277 (2005).
    • (2005) J. Health Sci. , vol.51 , pp. 272-277
    • Nakashima, K.1
  • 16
    • 1642458207 scopus 로고    scopus 로고
    • Mixed-mode solidphase extraction procedures for the determination of MDMA and metabolites in urine using LC-MS, LC-UV, or GC-NPD
    • K.M. Jenkins, M.S. Young, and C.R. Mallet. Mixed-mode solidphase extraction procedures for the determination of MDMA and metabolites in urine using LC-MS, LC-UV, or GC-NPD. J. Anal. Toxicol. 28: 50-58 (2004).
    • (2004) J. Anal. Toxicol. , vol.28 , pp. 50-58
    • Jenkins, K.M.1    Young, M.S.2    Mallet, C.R.3
  • 17
    • 0343819840 scopus 로고    scopus 로고
    • Analysis of underivatized amphetamines and related phenethylamines with high-performance liquid chromatography-atmospheric pressure chemical ionization mass spectrometry
    • M.J. Bogusz, K.D. Krüger, and R.D. Maier. Analysis of underivatized amphetamines and related phenethylamines with high-performance liquid chromatography-atmospheric pressure chemical ionization mass spectrometry. J. Anal. Toxicol. 24: 77-84 (2000).
    • (2000) J. Anal. Toxicol. , vol.24 , pp. 77-84
    • Bogusz, M.J.1    Krüger, K.D.2    Maier, R.D.3
  • 18
    • 33845332424 scopus 로고    scopus 로고
    • Quantitative determination of total methamphetamine and active metabolites in rat tissue by liquid chromatography with tandem mass spectrometric detection
    • H. Hendrickson, E. Laurenzana, and S.M. Owens. Quantitative determination of total methamphetamine and active metabolites in rat tissue by liquid chromatography with tandem mass spectrometric detection. AAPS J. 22: E709-717 (2006).
    • (2006) AAPS J. , vol.22
    • Hendrickson, H.1    Laurenzana, E.2    Owens, S.M.3
  • 19
    • 0031832886 scopus 로고    scopus 로고
    • Gas chromatography- Electron ionization and chemical ionization mass spectrometric analysis of urinary phenmetrazine after derivatization with 4-carbethoxyhexafluorobutyryl chloride-a new derivative
    • A. Dasgupta, A. Hart, P. Humphrey, and W. Blackwell. Gas chromatography- electron ionization and chemical ionization mass spectrometric analysis of urinary phenmetrazine after derivatization with 4-carbethoxyhexafluorobutyryl chloride-a new derivative. J. Forensic Sci. 43: 636-640 (1998).
    • (1998) J. Forensic Sci. , vol.43 , pp. 636-640
    • Dasgupta, A.1    Hart, A.2    Humphrey, P.3    Blackwell, W.4
  • 20
    • 42749085742 scopus 로고    scopus 로고
    • Analysis of amphetaminetype stimulants and their metabolites in plasma, urine and bile by liquid chromatography with a strong cation-exchange columntandem mass spectrometry
    • K. Kuwayama, H. Inoue, T. Kanamori, K. Tsujikawa, H. Miyaguchi, Y.T. Iwata, S. Miyauchi, and N. Kamo. Analysis of amphetaminetype stimulants and their metabolites in plasma, urine and bile by liquid chromatography with a strong cation-exchange columntandem mass spectrometry. J. Chromatogr. B 867: 78-83 (2008).
    • (2008) J. Chromatogr. B , vol.867 , pp. 78-83
    • Kuwayama, K.1    Inoue, H.2    Kanamori, T.3    Tsujikawa, K.4    Miyaguchi, H.5    Iwata, Y.T.6    Miyauchi, S.7    Kamo, N.8
  • 21
    • 0347083941 scopus 로고
    • Analysis of 3,4-methylenedioxymethamphetamine and its metabolites
    • K. Tanaka, T. Inoue, and H. Ohki. Analysis of 3,4- methylenedioxymethamphetamine and its metabolites. Rep. Natl. Res. Inst. Police Sci. 41: 114-119 (1988).
    • (1988) Rep. Natl. Res. Inst. Police Sci. , vol.41 , pp. 114-119
    • Tanaka, K.1    Inoue, T.2    Ohki, H.3
  • 22
    • 0000344093 scopus 로고
    • Studies on metabolism of methamphetamine analogs 6. Analysis of dimethylamphetamine and its metabolites
    • T. Inoue and S. Suzuki. Studies on metabolism of methamphetamine analogs 6. Analysis of dimethylamphetamine and its metabolites. Rep. Natl. Res. Inst. Police Sci. 39: 228-234 (1986).
    • (1986) Rep. Natl. Res. Inst. Police Sci. , vol.39 , pp. 228-234
    • Inoue, T.1    Suzuki, S.2
  • 24
    • 0035987204 scopus 로고    scopus 로고
    • Catechol-O-Methyltransferase (COMT)-mediated methylation metabolism of endogenous bioactive catechols and modulation by endobiotics and xenobiotics: Importance in pathophysiology and pathogenesis
    • B.T. Zhu. Catechol-O-Methyltransferase (COMT)-mediated methylation metabolism of endogenous bioactive catechols and modulation by endobiotics and xenobiotics: importance in pathophysiology and pathogenesis. Curr. Drug Metab. 3: 321-349 (2002).
    • (2002) Curr. Drug Metab. , vol.3 , pp. 321-349
    • Zhu, B.T.1
  • 25
    • 0035958821 scopus 로고    scopus 로고
    • Decrease of methionine and S-adenosylmethionine and increase of homocysteine in treated patients with Parkinson's disease
    • T. Müller, D. Woitalla, B. Hauptmann, B. Fowler, and W. Kuhn. Decrease of methionine and S-adenosylmethionine and increase of homocysteine in treated patients with Parkinson's disease. Neurosci. Lett. 308: 54-56 (2001).
    • (2001) Neurosci. Lett. , vol.308 , pp. 54-56
    • Müller, T.1    Woitalla, D.2    Hauptmann, B.3    Fowler, B.4    Kuhn, W.5
  • 26
    • 33646593148 scopus 로고    scopus 로고
    • Urinary excretion of the main metabolites of methamphetamine, including p-hydroxymethamphetamine-sulfate and p-hydroxymethamphetamine-glucuronide, in humans and rats
    • N. Shima, H.T. Kamata, M. Katagi, and H. Tsuchihashi.Urinary excretion of the main metabolites of methamphetamine, including p-hydroxymethamphetamine- sulfate and p-hydroxymethamphetamine-glucuronide, in humans and rats. Xenobiotica 36: 259-267 (2006).
    • (2006) Xenobiotica , vol.36 , pp. 259-267
    • Shima, N.1    Kamata, H.T.2    Katagi, M.3    Tsuchihashi, H.4
  • 27
    • 39349110177 scopus 로고    scopus 로고
    • Urinary excretion of the main metabolites of 3,4- methylenedioxymethamphetamine (MDMA), including the sulfate and glucuronide of 4-hydroxy-3-methoxymethamphetamine (HMMA), in humans and rats
    • N. Shima, M. Katagi, H. Kamata, K. Zaitsu, T. Kamata, M. Nishikawa, A. Miki, H. Tsuchihashi, T. Sakuma, and N. Nemoto. Urinary excretion of the main metabolites of 3,4-methylenedioxymethamphetamine (MDMA), including the sulfate and glucuronide of 4-hydroxy-3-methoxymethamphetamine (HMMA), in humans and rats. Xenobiotica 38: 314-324 (2008).
    • (2008) Xenobiotica , vol.38 , pp. 314-324
    • Shima, N.1    Katagi, M.2    Kamata, H.3    Zaitsu, K.4    Kamata, T.5    Nishikawa, M.6    Miki, A.7    Tsuchihashi, H.8    Sakuma, T.9    Nemoto, N.10
  • 28
  • 30
    • 54349126394 scopus 로고    scopus 로고
    • The role of human hepatic cytochrome P450 isozymes in the metabolism of racemic 3,4- Methylenedioxy-methamphetamine and its enantiomers
    • M.R. Meyer, F.T. Peters, and H.H. Maurer. The role of human hepatic cytochrome P450 isozymes in the metabolism of racemic 3,4- methylenedioxy- methamphetamine and its enantiomers. Drug Metab. Dispos. 36: 2345-2354 (2008).
    • (2008) Drug Metab. Dispos. , vol.36 , pp. 2345-2354
    • Meyer, M.R.1    Peters, F.T.2    Maurer, H.H.3
  • 31
    • 0034092057 scopus 로고    scopus 로고
    • Identification of the human cytochromes P450 involved in the oxidative metabolism of "Ecstasy"-related designer drugs
    • K. Kreth, K. Kovar, M. Schwab, and U.M. Zanger. Identification of the human cytochromes P450 involved in the oxidative metabolism of "Ecstasy"-related designer drugs. Biochem. Pharmacol. 59: 1563-1571 (2000).
    • (2000) Biochem. Pharmacol. , vol.59 , pp. 1563-1571
    • Kreth, K.1    Kovar, K.2    Schwab, M.3    Zanger, U.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.