Mitochondrial/lysosomal toxic cross-talk plays a key role in cisplatin nephrotoxicity

Xenobiotica

Volumn 40, Issue 11, 2010, Pages 763-771

  Pourahmad, Jalal ^a   Hosseini, Mir Jamal ^a   Eskandari, Mohammad Reza ^a   Shekarabi, Seyed Mohammad ^a   Daraei, Bahram ^a  

^a SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Cisplatin; Mitochondrial lysosomal cross talk; Nephrotoxicity; Oxidative stress; Renal proximal tubular (RPT) cells

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANTIOXIDANT; CASPASE 3; CISPLATIN; CYTOCHROME P450 2E1; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; SCAVENGER;

ANIMAL CELL; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; CYTOLYSIS; DRUG CYTOTOXICITY; ENZYME ACTIVITY; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE CELL; LYSOSOME MEMBRANE; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL PERMEABILITY; MITOCHONDRION; MOLECULAR INTERACTION; NEPHROTOXICITY; NONHUMAN; OXIDATIVE STRESS; RAT;

ANIMALS; ANTINEOPLASTIC AGENTS; CASPASE 3; CELLS, CULTURED; CISPLATIN; KIDNEY DISEASES; KIDNEY TUBULES, PROXIMAL; LYSOSOMES; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RECEPTOR CROSS-TALK;

EID: 77957965391     PISSN: 00498254     EISSN: 13665928     Source Type: Journal    
DOI: 10.3109/00498254.2010.512093     Document Type: Article

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