Biomarkers for the development of new medications for cocaine dependence

Neuropsychopharmacology

Volumn 39, Issue 1, 2014, Pages 202-219

  Bough, Kristopher J ^a   Amur, Shashi ^b   Lao, Guifang ^a   Hemby, Scott E ^c   Tannu, Nilesh S ^d   Kampman, Kyle M ^e   Schmitz, Joy M ^e   Martinez, Diana ^f   Merchant, Kalpana M ^g   Green, Charles ^d   Sharma, Jyoti ^d   Dougherty, Anne H ^h   Moeller, F Gerard ^h  

^a NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^b CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^c WAKE FOREST SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^e UNIVERSITY OF PENNSYLVANIA   (United States)

^f Och Spine at New York Presbyterian Hospitals   (United States)

^g ELI LILLY AND COMPANY   (United States)

^h VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

addiction; biomarkers; cocaine dependence; drug development tools

Indexed keywords

ADENOSINE; ALCOHOL; AMISULPRIDE; AMPHETAMINE; BENZODIAZEPINE; BENZOYLECGONINE; BETA ADRENERGIC RECEPTOR; BIOLOGICAL MARKER; BUPRENORPHINE PLUS NALOXONE; CATECHOLAMINE; COCAINE; DISULFIRAM; DOPAMINE; GUANINE; ILLICIT DRUG; KYNURENINE; LIGAND; METHAMPHETAMINE; MODAFINIL; MYELIN; MYELIN BASIC PROTEIN; OPIATE; PLACEBO; POTASSIUM CHANNEL; PRAMIPEXOLE; SEROTONIN; SODIUM CHANNEL; TOPIRAMATE; TOZADENANT; XANTHINE; PHARMACOLOGICAL BIOMARKER;

ACTIN FILAMENT; ADDICTION SEVERITY INDEX; ALCOHOL CONSUMPTION; ALCOHOLISM; ANTERIOR CINGULATE; ANXIETY; APPETITE; BLOOD PRESSURE; BRADYCARDIA; BRAIN FUNCTION; CAPSULA INTERNA; CARDIOVASCULAR FUNCTION; CAUDATE NUCLEUS; CELL FUNCTION; CELL MEMBRANE; CELL STRUCTURE; CINGULATE GYRUS; CLINICAL DECISION MAKING; CLINICAL PRACTICE; COCAINE DEPENDENCE; COGNITION; COGNITIVE THERAPY; COMORBIDITY; CORONARY ARTERY ATHEROSCLEROSIS; CORPUS CALLOSUM; CORPUS STRIATUM; DEPRESSION; DIFFUSION TENSOR IMAGING; DOPAMINE RELEASE; DOPAMINERGIC NERVE CELL; DOWN REGULATION; DRUG DETOXIFICATION; DRUG MISUSE; DRUG SEEKING BEHAVIOR; DRUG USE; DSM-IV; ELECTROCARDIOGRAM; EMERGENCY WARD; EXECUTIVE FUNCTION; FOLLOW UP; FRACTIONAL ANISOTROPY; FRONTAL CORTEX; FUNCTIONAL MAGNETIC RESONANCE IMAGING; FUNCTIONAL NEUROIMAGING; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOMICS; GENOTYPE; GLIA CELL; HEART; HEART FAILURE; HEART LEFT VENTRICLE HYPERTROPHY; HEART MUSCLE CONTRACTILITY; HEART RATE; HEROIN DEPENDENCE; HUMAN; HYPERPHAGIA; HYPOPHAGIA; IMPULSIVENESS; INCIDENCE; INFANCY; INFARCTION; INFERIOR FRONTAL GYRUS; INSULA; IRRITABILITY; ISCHEMIA; LETHARGY; LONG TERM EXPOSURE; MALIGNANT HYPERTENSION; MEDICAL HISTORY; MESENCEPHALON; METABOLOMICS; MICTURITION; MIDDLE FRONTAL GYRUS; MOTOR CONTROL; MYOCARDITIS; NERVE CELL PLASTICITY; NERVE FIBER; NERVOUS TISSUE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEUS ACCUMBENS; OPIATE ADDICTION; ORBITAL CORTEX; OUTCOME ASSESSMENT; OXYGEN CONSUMPTION; OXYGEN SUPPLY; PARANOIA; PHENOTYPE; PHYSICAL EXAMINATION; POSITRON EMISSION TOMOGRAPHY; POSTERIOR CINGULATE; POSTSYNAPTIC DENSITY; PREDICTIVE VALIDITY; PREDICTIVE VALUE; PREFRONTAL CORTEX; PREVALENCE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEOMICS; PUTAMEN; QRS COMPLEX; QT INTERVAL; QUESTIONNAIRE; RECEPTOR BINDING; REVIEW; REWARD; RISK FACTOR; SELF REPORT; SIGNAL DETECTION; SIGNAL TRANSDUCTION; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SINUS BRADYCARDIA; SLEEP; SOCIAL STRESS; STROOP TEST; SUBSTANCE ABUSE; SUBTHALAMIC NUCLEUS; SUPERIOR FRONTAL GYRUS; THALAMUS; THORAX PAIN; TRANSCRIPTOMICS; TREATMENT RESPONSE; UPREGULATION; VASOCONSTRICTION; VENTROMEDIAL PREFRONTAL CORTEX; WAKEFULNESS; WHITE MATTER; WITHDRAWAL SYNDROME; WORKING MEMORY; ANIMAL; CARDIOVASCULAR SYSTEM; COCAINE-RELATED DISORDERS; DRUG DEVELOPMENT; METABOLISM; NEUROIMAGING; PROCEDURES; SUBSTANCE-RELATED DISORDERS; TREATMENT OUTCOME;

ANIMALS; BIOMARKERS, PHARMACOLOGICAL; CARDIOVASCULAR SYSTEM; COCAINE-RELATED DISORDERS; DRUG DISCOVERY; HUMANS; NEUROIMAGING; SUBSTANCE-RELATED DISORDERS; TREATMENT OUTCOME;

EID: 84890497396     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2013.210     Document Type: Review

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