Sphingosine 1-phosphate receptors negatively regulate collagen type I/III expression in human bone marrow-derived mesenchymal stem cell

Journal of Cellular Biochemistry

Volumn 115, Issue 2, 2014, Pages 359-367

  Chang, Na ^a   Xiu, Lei ^a   Li, Liying ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Collagen; Human Mesenchymal Stem Cells; Sphingosine 1 Phosphate Receptor

Indexed keywords

COLLAGEN TYPE 1; COLLAGEN TYPE 3; MESSENGER RNA; SMALL INTERFERING RNA; SPHINGOSINE 1 PHOSPHATE RECEPTOR; SPHINGOSINE 2 PHOSPHATE RECEPTOR; SPHINGOSINE 3 PHOSPHATE RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; DOSE RESPONSE; DOWN REGULATION; GENE SILENCING; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; MESENCHYMAL STEM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REACTION TIME; REGULATORY MECHANISM; UPREGULATION;

COLLAGEN; HUMAN MESENCHYMAL STEM CELLS; SPHINGOSINE 1-PHOSPHATE RECEPTOR;

ANIMALS; BONE MARROW CELLS; CELL DIFFERENTIATION; COLLAGEN TYPE I; COLLAGEN TYPE III; GENE EXPRESSION REGULATION; HUMANS; LYSOPHOSPHOLIPIDS; MESENCHYMAL STROMAL CELLS; MICE; RECEPTORS, LYSOSPHINGOLIPID; RNA, SMALL INTERFERING; SPHINGOSINE;

EID: 84890496160     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.24670     Document Type: Article

References (47)

1. Akimova T, Ge G, Golovina T, Mikheeva T, Wang L, Riley JL, Hancock WW,. 2010. Histone/protein deacetylase inhibitors increase suppressive functions of human FOXP3+ Tregs. Clin Immunol 136: 348-363.
2. Bagchi RA, Czubryt MP,. 2012. Synergistic roles of scleraxis and Smads in the regulation of collagen 1alpha2 gene expression. Biochim Biophys Acta.
3. Bataller R, Brenner DA,. 2005. Liver fibrosis. J Clin Invest 115: 209-218.
4. Benamer N, Fares N, Bois P, Faivre JF,. 2011. Electrophysiological and functional effects of sphingosine-1-phosphate in mouse ventricular fibroblasts. Biochem Biophys Res Commun 408: 6-11.
5. Biernacka A, Dobaczewski M, Frangogiannis NG,. 2011. TGF-beta signaling in fibrosis. Growth Factors 29: 196-202.
6. Blobe GC, Schiemann WP, Lodish HF,. 2000. Role of transforming growth factor beta in human disease. N Engl J Med 342: 1350-1358.
7. Brinkmann V,. 2007. Sphingosine 1-phosphate receptors in health and disease: Mechanistic insights from gene deletion studies and reverse pharmacology. Pharmacol Ther 115: 84-105.
8. Brunati AM, Tibaldi E, Carraro A, Gringeri E, D'Amico FJ, Toninello A, Massimino ML, Pagano MA, Nalesso G, Cillo U,. 2008. Cross-talk between PDGF and S1P signalling elucidates the inhibitory effect and potential antifibrotic action of the immunomodulator FTY720 in activated HSC-cultures. Biochim Biophys Acta 1783: 347-359.
9. Bu S, Asano Y, Bujor A, Highland K, Hant F, Trojanowska M,. 2010. Dihydrosphingosine 1-phosphate has a potent antifibrotic effect in scleroderma fibroblasts via normalization of phosphatase and tensin homolog levels. Arthritis Rheum 62: 2117-2126.
10. Caplan AI,. 1991. Mesenchymal stem cells. J Orthop Res 9: 641-650.
11. Cencetti F, Bernacchioni C, Nincheri P, Donati C, Bruni P,. 2010. Transforming growth factor-beta1 induces transdifferentiation of myoblasts into myofibroblasts via up-regulation of sphingosine kinase-1/S1P3 axis. Mol Biol Cell 21: 1111-1124.
12. Cutroneo KR, White SL, Phan SH, Ehrlich HP,. 2007. Therapies for bleomycin induced lung fibrosis through regulation of TGF-beta1 induced collagen gene expression. J Cell Physiol 211: 585-589.
13. di Bonzo LV, Ferrero I, Cravanzola C, Mareschi K, Rustichell D, Novo E, Sanavio F, Cannito S, Zamara E, Bertero M, Davit A, Francica S, Novelli F, Colombatto S, Fagioli F, Parola M,. 2008. Human mesenchymal stem cells as a two-edged sword in hepatic regenerative medicine: Engraftment and hepatocyte differentiation versus profibrogenic potential. Gut 57: 223-231.
14. Fernandez IE, Eickelberg O,. 2012. The impact of TGF-beta on lung fibrosis: From targeting to biomarkers. Proc Am Thorac Soc 9: 111-116.
15. Gellings LN, Swaney JS, Moreno KM, Sabbadini RA,. 2009. Sphingosine-1-phosphate and sphingosine kinase are critical for transforming growth factor-beta-stimulated collagen production by cardiac fibroblasts. Cardiovasc Res 82: 303-312.
16. Ghosh AK,. 2002. Factors involved in the regulation of type I collagen gene expression: Implication in fibrosis. Exp Biol Med (Maywood) 227: 301-314.
17. Han KH, Lim S, Ryu J, Lee CW, Kim Y, Kang JH, Kang SS, Ahn YK, Park CS, Kim JJ,. 2009. CB1 and CB2 cannabinoid receptors differentially regulate the production of reactive oxygen species by macrophages. Cardiovasc Res 84: 378-386.
18. Hla T, Brinkmann V,. 2011. Sphingosine 1-phosphate (S1P): Physiology and the effects of S1P receptor modulation. Neurology 76: S3-S8.
19. Horie M, Choi H, Lee RH, Reger RL, Ylostalo J, Muneta T, Sekiya I, Prockop DJ,. 2012. Intra-articular injection of human mesenchymal stem cells (MSCs) promote rat meniscal regeneration by being activated to express Indian hedgehog that enhances expression of type II collagen. Osteoarthritis Cartilage 20: 1197-1207.
20. Hsu A, Zhang W, Lee JF, An J, Ekambaram P, Liu J, Honn KV, Klinge CM, Lee MJ,. 2012. Sphingosine-1-phosphate receptor-3 signaling up-regulates epidermal growth factor receptor and enhances epidermal growth factor receptor-mediated carcinogenic activities in cultured lung adenocarcinoma cells. Int J Oncol 40: 1619-1626.
21. Ikeda H, Yatomi Y, Yanase M, Satoh H, Maekawa H, Ogata I, Ozaki Y, Takuwa Y, Mochida S, Fujiwara K,. 2000. Biological activities of novel lipid mediator sphingosine 1-phosphate in rat hepatic stellate cells. Am J Physiol Gastrointest Liver Physiol 279: G304-G310.
22. Itoh F, Itoh S, Adachi T, Ichikawa K, Matsumura Y, Takagi T, Festing M, Watanabe T, Weinstein M, Karlsson S, Kato M,. 2012. Smad2/Smad3 in endothelium is indispensable for vascular stability via S1PR1 and N-cadherin expressions. Blood 119: 5320-5328.
23. Jeon ES, Moon HJ, Lee MJ, Song HY, Kim YM, Bae YC, Jung JS, Kim JH,. 2006. Sphingosylphosphorylcholine induces differentiation of human mesenchymal stem cells into smooth-muscle-like cells through a TGF-beta-dependent mechanism. J Cell Sci 119: 4994-5005.
24. Kono Y, Nishiuma T, Nishimura Y, Kotani Y, Okada T, Nakamura S, Yokoyama M,. 2007. Sphingosine kinase 1 regulates differentiation of human and mouse lung fibroblasts mediated by TGF-beta1. Am J Respir Cell Mol Biol 37: 395-404.
25. Krenning G, Zeisberg EM, Kalluri R,. 2010. The origin of fibroblasts and mechanism of cardiac fibrosis. J Cell Physiol 225: 631-637.
26. Lan HY,. 2011. Diverse roles of TGF-beta/Smads in renal fibrosis and inflammation. Int J Biol Sci 7: 1056-1067.
27. Li C, Jiang X, Yang L, Liu X, Yue S, Li L,. 2009a. Involvement of sphingosine 1-phosphate (SIP)/S1P3 signaling in cholestasis-induced liver fibrosis. Am J Pathol 175: 1464-1472.
28. Li C, Kong Y, Wang H, Wang S, Yu H, Liu X, Yang L, Jiang X, Li L, Li L,. 2009b. Homing of bone marrow mesenchymal stem cells mediated by sphingosine 1-phosphate contributes to liver fibrosis. J Hepatol 50: 1174-1183.
29. Li C, Zheng S, You H, Liu X, Lin M, Yang L, Li L,. 2011. Sphingosine 1-phosphate (S1P)/S1P receptors are involved in human liver fibrosis by action on hepatic myofibroblasts motility. J Hepatol 54: 1205-1213.
30. Lin SL, Kisseleva T, Brenner DA, Duffield JS,. 2008. Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney. Am J Pathol 173: 1617-1627.
31. Liu X, Yue S, Li C, Yang L, You H, Li L,. 2011. Essential roles of sphingosine 1-phosphate receptor types 1 and 3 in human hepatic stellate cells motility and activation. J Cell Physiol 226: 2370-2377.
32. Massague J,. 1998. TGF-beta signal transduction. Annu Rev Biochem 67: 753-791.
33. Matsuzaki K,. 2009. Modulation of TGF-beta signaling during progression of chronic liver diseases. Front Biosci 14: 2923-2934.
34. Medlin MD, Staus DP, Dubash AD, Taylor JM, Mack CP,. 2010. Sphingosine 1-phosphate receptor 2 signals through leukemia-associated RhoGEF (LARG), to promote smooth muscle cell differentiation. Arterioscler Thromb Vasc Biol 30: 1779-1786.
35. Pelttari K, Steck E, Richter W,. 2008. The use of mesenchymal stem cells for chondrogenesis. Injury 39 (Suppl. 1): S58-S65.
36. Peng WJ, Yan JW, Wan YN, Wang BX, Tao JH, Yang GJ, Pan HF, Wang J,. 2012. Matrix metalloproteinases: A review of their structure and role in systemic sclerosis. J Clin Immunol 32: 1409-1414.
37. Pittenger MF, Mackay AM, Beck SC, Jaiswal RK, Douglas R, Mosca JD, Moorman MA, Simonetti DW, Craig S, Marshak DR,. 1999. Multilineage potential of adult human mesenchymal stem cells. Science 284: 143-147.
38. Ricard-Blum S,. 2011. The collagen family. Cold Spring Harb Perspect Biol 3: a004978.
39. Russo FP, Alison MR, Bigger BW, Amofah E, Florou A, Amin F, Bou-Gharios G, Jeffery R, Iredale JP, Forbes SJ,. 2006. The bone marrow functionally contributes to liver fibrosis. Gastroenterology 130: 1807-1821.
40. Sanchez T, Hla T,. 2004. Structural and functional characteristics of S1P receptors. J Cell Biochem 92: 913-922.
41. Shoulders MD, Raines RT,. 2009. Collagen structure and stability. Annu Rev Biochem 78: 929-958.
42. Takeshita H, Kitano M, Iwasaki T, Kitano S, Tsunemi S, Sato C, Sekiguchi M, Azuma N, Miyazawa K, Hla T, Sano H,. 2012. Sphingosine 1-phosphate (S1P)/S1P receptor 1 signaling regulates receptor activator of NF-kappaB ligand (RANKL) expression in rheumatoid arthritis. Biochem Biophys Res Commun 419: 154-159.
43. Uccelli A, Moretta L, Pistoia V,. 2008. Mesenchymal stem cells in health and disease. Nat Rev Immunol 8: 726-736.
44. Vo BT, Morton DJ, Komaragiri S, Millena AC, Leath C, Khan SA,. 2013. TGF-beta effects on prostate cancer cell migration and invasion are mediated by PGE2 through activation of PI3K/AKT/mTOR pathway. Endocrinology 154: 1768-1779.
45. Yang L, Chang N, Liu X, Han Z, Zhu T, Li C, Yang L, Li L,. 2012. Bone marrow-derived mesenchymal stem cells differentiate to hepatic myofibroblasts by transforming growth factor-beta1 via sphingosine kinase/sphingosine 1-phosphate (S1P)/S1P receptor axis. Am J Pathol 181: 85-97.
46. Zhang H, Liu L, Wang Y, Zhao G, Xie R, Liu C, Xiao X, Wu K, Nie Y, Zhang H, Fan D,. 2013. KLF8 involves in TGF-beta-induced EMT and promotes invasion and migration in gastric cancer cells. J Cancer Res Clin Oncol 139: 1033-1042.
47. Zock JM,. 2009. Applications of high content screening in life science research. Comb Chem High Throughput Screen 12: 870-876.