Synthesis, characterization and crystal structure of cobalt(III) complexes containing 2-acetylpyridine thiosemicarbazones: DNA/protein interaction, radical scavenging and cytotoxic activities

Journal of Photochemistry and Photobiology B: Biology

Volumn 130, Issue , 2014, Pages 205-216

  Manikandan, Rajendran ^a   Viswanathamurthi, Periasamy ^a   Velmurugan, Krishnaswamy ^b   Nandhakumar, Raju ^b   Hashimoto, Takeshi ^c   Endo, Akira ^c  

^a PERIYAR UNIVERSITY   (India)

^b KARUNYA UNIVERSITY   (India)

^c SOPHIA UNIVERSITY   (Japan)

Author keywords

Antioxidant activity; Cobalt(III) complexes; Cytotoxicity; DNA binding; DNA cleavage; Protein binding

Indexed keywords

2 ACETYLPYRIDINE 4 METHYL THIOSEMICARBAZONE; 2 ACETYLPYRIDINE 4 PHENYL THIOSEMICARBAZONE; 2 ACETYLPYRIDINE THIOSEMICARBAZONE; BOVINE SERUM ALBUMIN; COBALT COMPLEX; DNA; HYDROXYL RADICAL; METHYLENE BLUE; NITRIC OXIDE; SCAVENGER; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING AFFINITY; BINDING SITE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DNA BINDING; DNA CLEAVAGE; DRUG STRUCTURE; DRUG SYNTHESIS; FLUORESCENCE; GEL ELECTROPHORESIS; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; INTERCALATION COMPLEX; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN DNA INTERACTION; X RAY DIFFRACTION;

BOVINAE;

ANTIOXIDANT ACTIVITY; COBALT(III) COMPLEXES; CYTOTOXICITY; DNA BINDING; DNA CLEAVAGE; PROTEIN BINDING;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; COBALT; COORDINATION COMPLEXES; DNA; DNA CLEAVAGE; FREE RADICAL SCAVENGERS; HUMANS; PROTEIN BINDING; SERUM ALBUMIN, BOVINE; THIOSEMICARBAZONES; X-RAY DIFFRACTION;

EID: 84890472266     PISSN: 10111344     EISSN: 18732682     Source Type: Journal    
DOI: 10.1016/j.jphotobiol.2013.11.008     Document Type: Article

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