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Volumn 30, Issue 8, 2013, Pages 969-976

Host pigment epithelium-derived factor (PEDF) prevents progression of liver metastasis in a mouse model of uveal melanoma

Author keywords

Angiogenesis; Metastasis; PEDF; Stromagenesis; Uveal melanoma

Indexed keywords

COLLAGEN TYPE 3; PIGMENT EPITHELIUM DERIVED FACTOR;

EID: 84890429106     PISSN: 02620898     EISSN: 15737276     Source Type: Journal    
DOI: 10.1007/s10585-013-9596-3     Document Type: Article
Times cited : (30)

References (55)
  • 1
    • 80052494912 scopus 로고    scopus 로고
    • Uveal melanoma: Trends in incidence, treatment, and survival
    • 21704381 10.1016/j.ophtha.2011.01.040
    • Singh A et al (2011) Uveal melanoma: trends in incidence, treatment, and survival. Ophthalmology 118:1881-1885
    • (2011) Ophthalmology , vol.118 , pp. 1881-1885
    • Singh, A.1
  • 2
    • 84890440191 scopus 로고    scopus 로고
    • Uveal melanoma: Where are we going?
    • Damato B et al (2011) Uveal melanoma: Where are we going? US Ophthalmic Review 4(1):105-107
    • (2011) US Ophthalmic Review , vol.4 , Issue.1 , pp. 105-107
    • Damato, B.1
  • 3
    • 0042021703 scopus 로고    scopus 로고
    • Ocular melanoma: A review and the relationship to cutaneous melanoma
    • 12925397 10.1001/archderm.139.8.1067
    • Hurst E et al (2003) Ocular melanoma: a review and the relationship to cutaneous melanoma. Arch Dermatol 139:1067-1073
    • (2003) Arch Dermatol , vol.139 , pp. 1067-1073
    • Hurst, E.1
  • 4
    • 0029025203 scopus 로고
    • Risks of second primary malignancy in patients with cutaneous and ocular melanoma in Denmark, 1943-1989
    • 7790110 10.1002/ijc.2910610606 1:STN:280:DyaK2MzhtVSmsQ%3D%3D
    • Swerdlow A et al (1995) Risks of second primary malignancy in patients with cutaneous and ocular melanoma in Denmark, 1943-1989. Int J Cancer 61:773-779
    • (1995) Int J Cancer , vol.61 , pp. 773-779
    • Swerdlow, A.1
  • 5
    • 0037056215 scopus 로고    scopus 로고
    • Sun exposure predicts risk of ocular melanoma in Australia
    • 12209995 10.1002/ijc.10579 1:CAS:528:DC%2BD38XmslCks7w%3D
    • Vajdic C et al (2002) Sun exposure predicts risk of ocular melanoma in Australia. Int J Cancer 101:175-182
    • (2002) Int J Cancer , vol.101 , pp. 175-182
    • Vajdic, C.1
  • 6
    • 14844301697 scopus 로고    scopus 로고
    • Uveal melanoma: Genetic aspects
    • 10.1016/j.ohc.2004.08.004
    • Singh A et al (2005) Uveal melanoma: genetic aspects. Ophthalmol Clini N. Am. 18:85-97
    • (2005) Ophthalmol Clini N. Am. , vol.18 , pp. 85-97
    • Singh, A.1
  • 7
    • 55749112322 scopus 로고    scopus 로고
    • The biology and management of uveal melanoma
    • 18706273 10.1007/s11912-008-0066-z 1:CAS:528:DC%2BD1cXhtFKntLvI
    • Sato T et al (2008) The biology and management of uveal melanoma. Curr Oncol Rep 10:431-438
    • (2008) Curr Oncol Rep , vol.10 , pp. 431-438
    • Sato, T.1
  • 8
    • 84866260326 scopus 로고    scopus 로고
    • Uveal melanoma dormancy: An acceptable clinical endpoint?
    • 22895346 10.1097/CMR.0b013e328357bea8
    • Blanco PL et al (2012) Uveal melanoma dormancy: an acceptable clinical endpoint? Melanoma Res 22(5):334-340
    • (2012) Melanoma Res , vol.22 , Issue.5 , pp. 334-340
    • Blanco, P.L.1
  • 9
    • 84876215338 scopus 로고    scopus 로고
    • Progression of ocular melanoma metastasis to the liver: The 2012 Zimmerman lecture
    • 23392528 10.1001/jamaophthalmol.2013.2547 1:CAS:528:DC%2BC3sXns1aku7g%3D
    • Grossniklaus H et al (2013) progression of ocular melanoma metastasis to the liver: the 2012 Zimmerman lecture. JAMA Ophthalmol 131(4):462-469
    • (2013) JAMA Ophthalmol , vol.131 , Issue.4 , pp. 462-469
    • Grossniklaus, H.1
  • 10
    • 84860618749 scopus 로고    scopus 로고
    • Comparison of formalin-fixed and snap frozen samples analyzed by multiplex ligation-dependent probe amplification for prognostic testing in uveal melanoma
    • Lake S et al (2012) Comparison of formalin-fixed and snap frozen samples analyzed by multiplex ligation-dependent probe amplification for prognostic testing in uveal melanoma. Anat Pathol 53(6):2647-2652
    • (2012) Anat Pathol , vol.53 , Issue.6 , pp. 2647-2652
    • Lake, S.1
  • 11
    • 5644251671 scopus 로고    scopus 로고
    • Gene expression profiling in uveal melanoma reveals two molecular classes and predicts metastatic death
    • 15492234 10.1158/0008-5472.CAN-04-1750 1:CAS:528:DC%2BD2cXosFyntrs%3D
    • Onken M et al (2004) Gene expression profiling in uveal melanoma reveals two molecular classes and predicts metastatic death. Cancer Res 64(20):7205-7209
    • (2004) Cancer Res , vol.64 , Issue.20 , pp. 7205-7209
    • Onken, M.1
  • 12
    • 84855809681 scopus 로고    scopus 로고
    • Multiplex ligation-dependent probe amplification equals fluorescence in situ hybridization for the identification of patients at risk for metastatic disease in uveal melanoma
    • 22157614 10.1097/CMR.0b013e32834e6a67 1:CAS:528:DC%2BC38Xmt1Cmsg%3D%3D
    • Vaarwater J et al (2012) Multiplex ligation-dependent probe amplification equals fluorescence in situ hybridization for the identification of patients at risk for metastatic disease in uveal melanoma. Melanoma Res 22(1):30-37
    • (2012) Melanoma Res , vol.22 , Issue.1 , pp. 30-37
    • Vaarwater, J.1
  • 13
    • 58649083678 scopus 로고    scopus 로고
    • The prometastatic microenvironment of the liver
    • 19308690 10.1007/s12307-008-0011-6
    • Vidal-Vanaclocha F et al (2008) The prometastatic microenvironment of the liver. Cancer Microenviron 1(1):113-129
    • (2008) Cancer Microenviron , vol.1 , Issue.1 , pp. 113-129
    • Vidal-Vanaclocha, F.1
  • 14
    • 39749174411 scopus 로고    scopus 로고
    • Molecular pathways mediating liver metastasis in patients with uveal melanoma
    • 18281525 10.1158/1078-0432.CCR-06-2630 1:CAS:528:DC%2BD1cXhvF2ntL8%3D
    • Bakalian S et al (2008) Molecular pathways mediating liver metastasis in patients with uveal melanoma. Clin Cancer Res 14(4):951-956
    • (2008) Clin Cancer Res , vol.14 , Issue.4 , pp. 951-956
    • Bakalian, S.1
  • 15
    • 0031655802 scopus 로고    scopus 로고
    • Multistep nature of metastatic inefficiency: Dormancy of solitary cells after successful extravasation and limited survival of early micrometastases
    • 9736035 10.1016/S0002-9440(10)65628-3 1:STN:280:DyaK1cvgsFCnsA%3D%3D
    • Luzzi K et al (1998) Multistep nature of metastatic inefficiency: dormancy of solitary cells after successful extravasation and limited survival of early micrometastases. Am J Pathol 153(3):865-873
    • (1998) Am J Pathol , vol.153 , Issue.3 , pp. 865-873
    • Luzzi, K.1
  • 16
    • 34848924311 scopus 로고    scopus 로고
    • Cytogenetics of uveal melanoma: A 7-year clinical experience
    • 17719643 10.1016/j.ophtha.2007.06.012
    • Damato B et al (2007) Cytogenetics of uveal melanoma: a 7-year clinical experience. Ophthalmology 114:1925-1931
    • (2007) Ophthalmology , vol.114 , pp. 1925-1931
    • Damato, B.1
  • 17
    • 80052648350 scopus 로고    scopus 로고
    • Molecular alterations in uveal melanoma
    • 21911184 10.1016/j.currproblcancer.2011.07.004
    • Materin M et al (2011) Molecular alterations in uveal melanoma. Curr Probl Cancer 35(4):211-224
    • (2011) Curr Probl Cancer , vol.35 , Issue.4 , pp. 211-224
    • Materin, M.1
  • 18
    • 78649700287 scopus 로고    scopus 로고
    • Frequent mutation of bap1 in metastasizing uveal melanomas
    • 21051595 10.1126/science.1194472 1:CAS:528:DC%2BC3cXhsVyrsbbI
    • Harbour J et al (2010) Frequent mutation of bap1 in metastasizing uveal melanomas. Science 330:1410-1413
    • (2010) Science , vol.330 , pp. 1410-1413
    • Harbour, J.1
  • 19
    • 34547225107 scopus 로고    scopus 로고
    • Transcriptional profiling of human uveal melanoma from cell lines to intraocular tumors to metastasis
    • 10.1007/s10585-007-9072-z 1:CAS:528:DC%2BD2sXhtVGrurrM
    • Marshall J et al (2007) Transcriptional profiling of human uveal melanoma from cell lines to intraocular tumors to metastasis. Clin Exp Met 24:353-362
    • (2007) Clin Exp Met , vol.24 , pp. 353-362
    • Marshall, J.1
  • 20
    • 0036597825 scopus 로고    scopus 로고
    • HLA expression in uveal melanoma: There is no rule without some exception
    • 12039519 10.1016/S0198-8859(02)00389-0 1:CAS:528:DC%2BD38XktVCrsL4%3D
    • Jager M et al (2002) HLA expression in uveal melanoma: there is no rule without some exception. Hum Immunol 63:444-451
    • (2002) Hum Immunol , vol.63 , pp. 444-451
    • Jager, M.1
  • 21
    • 0036187615 scopus 로고    scopus 로고
    • The role of tumour-associated macrophages in tumour progression: Implications for new anticancer therapies
    • 11857487 10.1002/path.1027 1:STN:280:DC%2BD387it1eksQ%3D%3D
    • Bingle L et al (2002) The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies. J Pathol 196:254-265
    • (2002) J Pathol , vol.196 , pp. 254-265
    • Bingle, L.1
  • 22
    • 23744432972 scopus 로고    scopus 로고
    • Stromagenesis: The changing face of fibroblastic microenvironments during tumor progression
    • 15970443 10.1016/j.semcancer.2005.05.003
    • Beacham D et al (2005) Stromagenesis: the changing face of fibroblastic microenvironments during tumor progression. Semin Cancer Biol 15(5):329-341
    • (2005) Semin Cancer Biol , vol.15 , Issue.5 , pp. 329-341
    • Beacham, D.1
  • 23
    • 84868005326 scopus 로고    scopus 로고
    • 18a-glycyrrhetinic acid down-regulates expression of type i and iii collagen via tgf-b1/smad signaling pathway in human and rat hepatic stellate cells
    • 22811611 10.7150/ijms.4395 1:CAS:528:DC%2BC38XhtVyisbvO
    • Zong L (2012) 18a-glycyrrhetinic acid down-regulates expression of type i and iii collagen via tgf-b1/smad signaling pathway in human and rat hepatic stellate cells. Int J Med Sci 9(5):370-379
    • (2012) Int J Med Sci , vol.9 , Issue.5 , pp. 370-379
    • Zong, L.1
  • 24
    • 0033538517 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor: A potent inhibitor of angiogenesis
    • 10398599 10.1126/science.285.5425.245 1:CAS:528:DyaK1MXks1SjtLo%3D
    • Dawson D et al (1999) Pigment epithelium-derived factor: a potent inhibitor of angiogenesis. Science 285:245-248
    • (1999) Science , vol.285 , pp. 245-248
    • Dawson, D.1
  • 25
    • 84858780407 scopus 로고    scopus 로고
    • Hypoxia negatively regulates antimetastatic pedf in melanoma cells by a hypoxia inducible factor-independent, autophagy dependent mechanism
    • 22457728 10.1371/journal.pone.0032989
    • Fernández-Barral A et al (2012) Hypoxia negatively regulates antimetastatic pedf in melanoma cells by a hypoxia inducible factor-independent, autophagy dependent mechanism. PloS one 7(3):e32989
    • (2012) PloS One , vol.7 , Issue.3 , pp. 32989
    • Fernández-Barral, A.1
  • 26
    • 77957351496 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor is an intrinsic antifibrosis factor targeting hepatic stellate cells
    • 10.2353/ajpath.2010.091085 20709803 10.2353/ajpath.2010.091085 1:CAS:528:DC%2BC3cXhsVSqu7nK
    • Ho T et al (2010) Pigment epithelium-derived factor is an intrinsic antifibrosis factor targeting hepatic stellate cells. Am J Pathol 177(4):1798-1811. doi: 10.2353/ajpath.2010.091085
    • (2010) Am J Pathol , vol.177 , Issue.4 , pp. 1798-1811
    • Ho, T.1
  • 27
    • 70949107165 scopus 로고    scopus 로고
    • Loss of pigment epithelium-derived factor enables migration, invasion and metastatic spread of human melanoma
    • 19767774 10.1038/onc.2009.284 1:CAS:528:DC%2BD1MXhtFGjt7jK
    • Orgaz J et al (2009) Loss of pigment epithelium-derived factor enables migration, invasion and metastatic spread of human melanoma. Oncogene 28(47):4147-4161
    • (2009) Oncogene , vol.28 , Issue.47 , pp. 4147-4161
    • Orgaz, J.1
  • 28
    • 67449101292 scopus 로고    scopus 로고
    • Laminin receptor involvement in the anti-angiogenic activity of pigment epithelium-derived factor
    • 19224861 10.1074/jbc.M809259200 1:CAS:528:DC%2BD1MXktlGkt7k%3D
    • Bernard A et al (2009) Laminin receptor involvement in the anti-angiogenic activity of pigment epithelium-derived factor. J Biol Chem 284(16):10480-10490
    • (2009) J Biol Chem , vol.284 , Issue.16 , pp. 10480-10490
    • Bernard, A.1
  • 29
    • 77951241740 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor binds to cell-surface F1-ATP synthase
    • 20412062 10.1111/j.1742-4658.2010.07641.x 1:CAS:528:DC%2BC3cXlvFejtb8%3D
    • Notari L et al (2010) Pigment epithelium-derived factor binds to cell-surface F1-ATP synthase. FEBS J 277:2192-2205
    • (2010) FEBS J , vol.277 , pp. 2192-2205
    • Notari, L.1
  • 30
    • 33845989501 scopus 로고    scopus 로고
    • Identification of a lipase-linked cell membrane receptor for pigment epithelium-derived factor
    • 17032652 10.1074/jbc.M600353200 1:CAS:528:DC%2BD28Xht1Kit7zL
    • Notari L et al (2006) Identification of a lipase-linked cell membrane receptor for pigment epithelium-derived factor. J Biol Chem 281(49):38022-38037
    • (2006) J Biol Chem , vol.281 , Issue.49 , pp. 38022-38037
    • Notari, L.1
  • 31
    • 33747879267 scopus 로고    scopus 로고
    • PEDF induces apoptosis in human endothelial cells by activating p38 MAP kinase dependent cleavage of multiple caspases
    • 16919597 10.1016/j.bbrc.2006.07.188 1:CAS:528:DC%2BD28XovVWrtb4%3D
    • Chen L et al (2006) PEDF induces apoptosis in human endothelial cells by activating p38 MAP kinase dependent cleavage of multiple caspases. Biochem Biophys Res Commun 348(4):1288-1295
    • (2006) Biochem Biophys Res Commun , vol.348 , Issue.4 , pp. 1288-1295
    • Chen, L.1
  • 32
    • 0036104828 scopus 로고    scopus 로고
    • Inducer-stimulated Fas targets activated endothelium for destruction by anti-angiogenic thrombospondin-1 and pigment epithelium-derived factor
    • 11927940 10.1038/nm0402-349 1:CAS:528:DC%2BD38XivVGmsLY%3D
    • Volpert O et al (2002) Inducer-stimulated Fas targets activated endothelium for destruction by anti-angiogenic thrombospondin-1 and pigment epithelium-derived factor. Nat Med 8(4):349-357
    • (2002) Nat Med , vol.8 , Issue.4 , pp. 349-357
    • Volpert, O.1
  • 33
    • 33645635929 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor inhibits angiogenesis via regulated intracellular proteolysis of vascular endothelial growth factor receptor 1
    • 16339148 10.1074/jbc.M507401200 1:CAS:528:DC%2BD28XhtFSmtrc%3D
    • Cai J et al (2006) Pigment epithelium-derived factor inhibits angiogenesis via regulated intracellular proteolysis of vascular endothelial growth factor receptor 1. J Biol Chem 281(6):3604-3613
    • (2006) J Biol Chem , vol.281 , Issue.6 , pp. 3604-3613
    • Cai, J.1
  • 34
    • 33747893515 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor downregulates vascular endothelial growth factor (VEGF) expression and inhibits VEGF-VEGF receptor 2 binding in diabetic retinopathy
    • 16901919 10.1677/jme.1.02008
    • Zhang S et al (2006) Pigment epithelium-derived factor downregulates vascular endothelial growth factor (VEGF) expression and inhibits VEGF-VEGF receptor 2 binding in diabetic retinopathy. J Mol Endocrinol 37(1):1-12
    • (2006) J Mol Endocrinol , vol.37 , Issue.1 , pp. 1-12
    • Zhang, S.1
  • 35
    • 84866118062 scopus 로고    scopus 로고
    • Concurrent PEDF deficiency and Kras mutation induce invasive pancreatic cancer and adipose-rich stroma in mice
    • 22234980 10.1136/gutjnl-2011-300821 1:CAS:528:DC%2BC38Xhs1Kmt7bL
    • Grippo P, Fitchev P, Bentrem D, Melstrom L (2012) Concurrent PEDF deficiency and Kras mutation induce invasive pancreatic cancer and adipose-rich stroma in mice. Gut 61(10):1454-1464
    • (2012) Gut , vol.61 , Issue.10 , pp. 1454-1464
    • Grippo, P.1    Fitchev, P.2    Bentrem, D.3    Melstrom, L.4
  • 36
    • 41149164902 scopus 로고    scopus 로고
    • The Yin-Yang of tumor-associated macrophages in neoplastic progression and immune surveillance
    • 18364000 10.1111/j.1600-065X.2008.00607.x 1:CAS:528:DC%2BD1cXlsFejtrc%3D
    • Allavena P et al (2008) The Yin-Yang of tumor-associated macrophages in neoplastic progression and immune surveillance. Immunol Rev 222:155-161
    • (2008) Immunol Rev , vol.222 , pp. 155-161
    • Allavena, P.1
  • 37
    • 24644506292 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor is a substrate for matrix metalloproteinase type 2 and type 9: Implications for downregulation in hypoxia
    • 16043845 10.1167/iovs.04-1489
    • Notari L et al (2005) Pigment epithelium-derived factor is a substrate for matrix metalloproteinase type 2 and type 9: implications for downregulation in hypoxia. Invest Ophthalmol Vis Sci 46(8):2736-2747
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , Issue.8 , pp. 2736-2747
    • Notari, L.1
  • 38
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • 8756718 10.1016/S0092-8674(00)80108-7 1:CAS:528:DyaK28XltVSks7s%3D
    • Hanahan D et al (1996) Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 86(3):353-364
    • (1996) Cell , vol.86 , Issue.3 , pp. 353-364
    • Hanahan, D.1
  • 39
    • 33646887537 scopus 로고    scopus 로고
    • Angiostatin decreases cell migration and vascular endothelium growth factor (VEGF) to pigment epithelium derived factor (PEDF) RNA ratio in vitro and in a murine ocular melanoma model
    • 16735992 1:CAS:528:DC%2BD28XntVels7k%3D
    • Yang H et al (2006) Angiostatin decreases cell migration and vascular endothelium growth factor (VEGF) to pigment epithelium derived factor (PEDF) RNA ratio in vitro and in a murine ocular melanoma model. Mol Vis 12:511-517
    • (2006) Mol Vis , vol.12 , pp. 511-517
    • Yang, H.1
  • 40
    • 75749111061 scopus 로고    scopus 로고
    • Constitutive overexpression of pigment epithelium-derived factor inhibition of ocular melanoma growth and metastasis
    • 19661223 10.1167/iovs.09-4138
    • Yang H et al (2010) Constitutive overexpression of pigment epithelium-derived factor inhibition of ocular melanoma growth and metastasis. Invest Ophthalmol Vis Sci 51(1):28-34
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , Issue.1 , pp. 28-34
    • Yang, H.1
  • 41
    • 4143109252 scopus 로고    scopus 로고
    • Inhibition of xenografted human melanoma growth and prevention of metastasis development by dual antiangiogenic/antitumor activities of pigment epithelium-derived factor
    • 15313901 10.1158/0008-5472.CAN-04-0230 1:CAS:528:DC%2BD2cXmslalurg%3D
    • Garcia M et al (2004) Inhibition of xenografted human melanoma growth and prevention of metastasis development by dual antiangiogenic/antitumor activities of pigment epithelium-derived factor. Cancer Res 64:5632-5642
    • (2004) Cancer Res , vol.64 , pp. 5632-5642
    • Garcia, M.1
  • 42
    • 0033056328 scopus 로고    scopus 로고
    • B16LS9 melanoma cells spread to the liver from the murine ocular posterior compartment (PC)
    • 10223656 10.1076/ceyr.18.2.125.5380 1:CAS:528:DyaK1MXntlSrtLo%3D
    • Diaz C et al (1999) B16LS9 melanoma cells spread to the liver from the murine ocular posterior compartment (PC). Curr Eye Res 18(2):125-129
    • (1999) Curr Eye Res , vol.18 , Issue.2 , pp. 125-129
    • Diaz, C.1
  • 43
    • 0034053102 scopus 로고    scopus 로고
    • A new technique for implantation of tissue culture melanoma cells in a murine model of metastatic ocular melanoma
    • 10711634 1:STN:280:DC%2BD3c7nsVOktA%3D%3D
    • Dithmar S et al (2000) A new technique for implantation of tissue culture melanoma cells in a murine model of metastatic ocular melanoma. Melanoma Res 10(1):2-8
    • (2000) Melanoma Res , vol.10 , Issue.1 , pp. 2-8
    • Dithmar, S.1
  • 44
    • 0038240367 scopus 로고    scopus 로고
    • Pigment epithelium: Derived factor regulates the vasculature and mass of the prostate and pancreas
    • 12740569 10.1038/nm870
    • Cornwell M et al (2003) Pigment epithelium: derived factor regulates the vasculature and mass of the prostate and pancreas. Nat Med 9(6):774-780
    • (2003) Nat Med , vol.9 , Issue.6 , pp. 774-780
    • Cornwell, M.1
  • 45
    • 39149141058 scopus 로고    scopus 로고
    • Anti-angiogenic pigment epithelium-derived factor regulates hepatocyte triglyceride content through adipose triglyceride lipase (ATGL)
    • 18191271 10.1016/j.jhep.2007.10.012 1:CAS:528:DC%2BD1cXhsl2ms78%3D
    • Chung C et al (2008) Anti-angiogenic pigment epithelium-derived factor regulates hepatocyte triglyceride content through adipose triglyceride lipase (ATGL). J Hepatol 48:471-478
    • (2008) J Hepatol , vol.48 , pp. 471-478
    • Chung, C.1
  • 46
    • 40849142160 scopus 로고    scopus 로고
    • In-vivo xenograft murine human uveal melanoma model develops hepatic micrometastases
    • 18337645 10.1097/CMR.0b013e3282f628df
    • Yang H et al (2008) In-vivo xenograft murine human uveal melanoma model develops hepatic micrometastases. Melanoma Res 18(2):95-103
    • (2008) Melanoma Res , vol.18 , Issue.2 , pp. 95-103
    • Yang, H.1
  • 47
    • 21244458956 scopus 로고    scopus 로고
    • Low dose adjuvant angiostatin decreases hepatic micrometastasis in murine ocular melanoma model
    • 15623988
    • Yang H et al (2004) Low dose adjuvant angiostatin decreases hepatic micrometastasis in murine ocular melanoma model. Mol Vis 10:987-995
    • (2004) Mol Vis , vol.10 , pp. 987-995
    • Yang, H.1
  • 48
    • 0030014569 scopus 로고    scopus 로고
    • Microvessel count predicts survival in uveal melanoma
    • 8674036 1:CAS:528:DyaK28XjvFCksLY%3D
    • Foss A et al (1996) Microvessel count predicts survival in uveal melanoma. Cancer Res 56:2900-2903
    • (1996) Cancer Res , vol.56 , pp. 2900-2903
    • Foss, A.1
  • 49
    • 50549121134 scopus 로고
    • The distribution of secondary growths in cancer of the breast
    • 10.1016/S0140-6736(00)49915-0
    • Paget S (1889) The distribution of secondary growths in cancer of the breast. Lancet 133:3421
    • (1889) Lancet , vol.133 , pp. 3421
    • Paget, S.1
  • 50
    • 0036984640 scopus 로고    scopus 로고
    • Role of angiogenesis in tumor growth and metastasis
    • 12516034 10.1016/S0093-7754(02)70065-1 1:CAS:528:DC%2BD3sXlvFSqtg%3D%3D
    • Folkman J (2002) Role of angiogenesis in tumor growth and metastasis. Semin Oncol 29(6):15-18
    • (2002) Semin Oncol , vol.29 , Issue.6 , pp. 15-18
    • Folkman, J.1
  • 51
    • 78650840036 scopus 로고    scopus 로고
    • Serum vascular endothelial growth factor (VEGF) levels correlate with number and location of micrometastases in a murine model of uveal melanoma
    • 20819828 10.1136/bjo.2010.182402
    • Crosby M et al (2011) Serum vascular endothelial growth factor (VEGF) levels correlate with number and location of micrometastases in a murine model of uveal melanoma. Br J Ophthalmol 95:112-117
    • (2011) Br J Ophthalmol , vol.95 , pp. 112-117
    • Gao, W.1
  • 52
    • 2542569400 scopus 로고    scopus 로고
    • Hypoxia-inducible factor (HIF-1) in cancer
    • 10.1016/j.ejso.2004.03.008
    • Quintero M et al (2004) Hypoxia-inducible factor (HIF-1) in cancer. Eur J Surg Oncol 5:465-468
    • (2004) Eur J Surg Oncol , vol.5 , pp. 465-468
    • Quintero, M.1
  • 53
    • 0028676049 scopus 로고
    • Murine model of liver metastasis
    • Rusciano D et al (1994) Murine model of liver metastasis. Invasion Metastasis 14(1-6):349-361
    • (1994) Invasion Metastasis , vol.14 , Issue.1-6 , pp. 349-361
    • Rusciano, D.1
  • 54
    • 0028808335 scopus 로고
    • Expression of constitutively activated hepatocyte growth factor/scatter factor receptor (c-met) in B16 melanoma cells selected for enhanced liver colonization
    • Rusciano D et al (1995) Expression of constitutively activated hepatocyte growth factor/scatter factor receptor (c-met) in B16 melanoma cells selected for enhanced liver colonization. Oncogene 11(10):1979-1987
    • (1995) Oncogene , vol.11 , Issue.10 , pp. 1979-1987
    • Rusciano, D.1
  • 55
    • 2442621280 scopus 로고    scopus 로고
    • Models of uveal melanoma: Characterization of transgenic mice and other animal models for melanoma
    • Albert D and Polans A (ed) CRC Press, Boca Raton
    • Dithmar S et al (2003) Models of uveal melanoma: characterization of transgenic mice and other animal models for melanoma. In: Albert D and Polans A (ed) Ocular Oncology, CRC Press, Boca Raton, p 284-309
    • (2003) Ocular Oncology , pp. 284-309
    • Dithmar, S.1


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