메뉴 건너뛰기




Volumn 10, Issue 5, 2008, Pages 431-438

The biology and management of uveal melanoma

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CALCITRIOL; CARBOPLATIN; CARMUSTINE; CEDIRANIB; CISPLATIN; CYCLOPHOSPHAMIDE; CYTOTOXIC AGENT; DNA VACCINE; FLUDARABINE PHOSPHATE; GLYCOPROTEIN GP 100; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IODINE 131; IPILIMUMAB; LENALIDOMIDE; LEUPRORELIN; MELAN A; MELANOMA ANTIGEN 3; MELPHALAN; PACLITAXEL; RADIOISOTOPE; SORAFENIB; SUNITINIB; TAMOXIFEN CITRATE; TEMOZOLOMIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VINCRISTINE SULFATE; VORINOSTAT; YTTRIUM 90; ZIRCONIUM 90; PHOSPHATIDYLINOSITOL 3 KINASE;

EID: 55749112322     PISSN: 15233790     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11912-008-0066-z     Document Type: Review
Times cited : (37)

References (50)
  • 2
    • 2442519348 scopus 로고    scopus 로고
    • Recent developments in the management of choroidal melanoma
    • Shields CL, Shields JA: Recent developments in the management of choroidal melanoma. Curr Opin Ophthalmol 2004, 15:244-251.
    • (2004) Curr Opin Ophthalmol , vol.15 , pp. 244-251
    • Shields, C.L.1    Shields, J.A.2
  • 3
    • 0025962917 scopus 로고
    • Survival of patients with metastases from uveal melanoma
    • discussion 390
    • Gragoudas ES, Egan KM, Seddon JM, et al.: Survival of patients with metastases from uveal melanoma. Ophthalmology 1991, 98:383-389; discussion 390.
    • (1991) Ophthalmology , vol.98 , pp. 383-389
    • Gragoudas, E.S.1    Egan, K.M.2    Seddon, J.M.3
  • 4
    • 0142200859 scopus 로고    scopus 로고
    • Very long-term prognosis of patients with malignant uveal melanoma
    • Kujala E, Makitie T, Kivela T: Very long-term prognosis of patients with malignant uveal melanoma. Invest Ophthalmol Vis Sci 2003, 44:4651-4659.
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , pp. 4651-4659
    • Kujala, E.1    Makitie, T.2    Kivela, T.3
  • 5
    • 0035025251 scopus 로고    scopus 로고
    • Assessment of metastatic disease status at death in 435 patients with large choroidal melanoma in the Collaborative Ocular Melanoma Study (COMS): COMS report no. 15
    • Assessment of metastatic disease status at death in 435 patients with large choroidal melanoma in the Collaborative Ocular Melanoma Study (COMS): COMS report no. 15. Arch Ophthalmol 2001, 119:670-676.
    • (2001) Arch Ophthalmol , vol.119 , pp. 670-676
  • 6
    • 33947230256 scopus 로고    scopus 로고
    • Distinct clinical and pathological features are associated with the BRAF(T1799A(V600E)) mutation in primary melanoma
    • Liu W, Kelly JW, Trivett M, et al.: Distinct clinical and pathological features are associated with the BRAF(T1799A(V600E)) mutation in primary melanoma. J Invest Dermatol 2007, 127:900-905.
    • (2007) J Invest Dermatol , vol.127 , pp. 900-905
    • Liu, W.1    Kelly, J.W.2    Trivett, M.3
  • 7
    • 18444374405 scopus 로고    scopus 로고
    • Mutations of the BRAF gene in human cancer
    • Davies H, Bignell GR, Cox C, et al.: Mutations of the BRAF gene in human cancer. Nature 2002, 417:949-954.
    • (2002) Nature , vol.417 , pp. 949-954
    • Davies, H.1    Bignell, G.R.2    Cox, C.3
  • 8
    • 0141842689 scopus 로고    scopus 로고
    • Absence of BRAF and NRAS mutations in uveal melanoma
    • Cruz F III, Rubin BP, Wilson D, et al.: Absence of BRAF and NRAS mutations in uveal melanoma. Cancer Res 2003, 63:5761-5766.
    • (2003) Cancer Res , vol.63 , pp. 5761-5766
    • Cruz III, F.1    Rubin, B.P.2    Wilson, D.3
  • 9
    • 0141961836 scopus 로고    scopus 로고
    • Familial melanoma: A complex disorder leading to controversy on DNA testing
    • de Snoo FA, BArgman W, Gruis NA: Familial melanoma: a complex disorder leading to controversy on DNA testing. Fam Cancer 2003, 2:109-116.
    • (2003) Fam Cancer , vol.2 , pp. 109-116
    • de Snoo, F.A.1    Bergman, W.2    Gruis, N.A.3
  • 10
    • 0027946010 scopus 로고
    • Rarity of somatic and germline mutations of the cyclin-dependent kinase 4 inhibitor gene, CDK4I, in melanoma
    • Ohta M, Nagai H, Shimizu M, et al.: Rarity of somatic and germline mutations of the cyclin-dependent kinase 4 inhibitor gene, CDK4I, in melanoma. Cancer Res 1994, 54:5269-5272.
    • (1994) Cancer Res , vol.54 , pp. 5269-5272
    • Ohta, M.1    Nagai, H.2    Shimizu, M.3
  • 12
    • 0031041186 scopus 로고    scopus 로고
    • Use of fluorescence in situ hybridization and comparative genomic hybridization in the cytogenetic analysis of testicular germ cell tumors and uveal melanomas
    • Becher R, Korn WM, Prescher G: Use of fluorescence in situ hybridization and comparative genomic hybridization in the cytogenetic analysis of testicular germ cell tumors and uveal melanomas. Cancer Genet Cytogenet 1997, 93:22-28.
    • (1997) Cancer Genet Cytogenet , vol.93 , pp. 22-28
    • Becher, R.1    Korn, W.M.2    Prescher, G.3
  • 13
    • 0035870290 scopus 로고    scopus 로고
    • Partial deletions of the long and short arm of chromosome 3 point to two tumor suppressor genes in uveal melanoma
    • Tschentscher F, Prescher G, Horsman DE, et al.: Partial deletions of the long and short arm of chromosome 3 point to two tumor suppressor genes in uveal melanoma. Cancer Res 2001, 61:3439-3442.
    • (2001) Cancer Res , vol.61 , pp. 3439-3442
    • Tschentscher, F.1    Prescher, G.2    Horsman, D.E.3
  • 14
    • 0033954096 scopus 로고    scopus 로고
    • Association of specific chromosome alterations with tumour phenotype in posterior uveal melanoma
    • Sisley K, Parsons MA, Garnham J, et al.: Association of specific chromosome alterations with tumour phenotype in posterior uveal melanoma. Br J Cancer 2000, 82:330-338.
    • (2000) Br J Cancer , vol.82 , pp. 330-338
    • Sisley, K.1    Parsons, M.A.2    Garnham, J.3
  • 15
    • 0033008658 scopus 로고    scopus 로고
    • C-myc, p53, and Bcl-2 expression and clinical outcome in uveal melanoma
    • Chana JS, Wilson GD, Cree IA, et al.: C-myc, p53, and Bcl-2 expression and clinical outcome in uveal melanoma. Br J Ophthalmol 1999, 83:110-114.
    • (1999) Br J Ophthalmol , vol.83 , pp. 110-114
    • Chana, J.S.1    Wilson, G.D.2    Cree, I.A.3
  • 16
    • 0033168843 scopus 로고    scopus 로고
    • Allelotype of posterior uveal melanoma: Implications for a bifurcated tumor progression pathway
    • Parrella P, Sidransky D, Merbs SL: Allelotype of posterior uveal melanoma: Implications for a bifurcated tumor progression pathway. Cancer Res 1999, 59:3032-3037.
    • (1999) Cancer Res , vol.59 , pp. 3032-3037
    • Parrella, P.1    Sidransky, D.2    Merbs, S.L.3
  • 17
    • 0345256382 scopus 로고    scopus 로고
    • Dissecting karyotypic patterns in malignant melanomas: Temporal clustering of losses and gains in melanoma karyotypic evolution
    • Hoglund M, Gisselsson D, Hansen GB, et al.: Dissecting karyotypic patterns in malignant melanomas: Temporal clustering of losses and gains in melanoma karyotypic evolution. Int J Cancer 2004, 108:57-65.
    • (2004) Int J Cancer , vol.108 , pp. 57-65
    • Hoglund, M.1    Gisselsson, D.2    Hansen, G.B.3
  • 19
    • 0029874486 scopus 로고    scopus 로고
    • Prognostic implications of monosomy 3 in uveal melanoma
    • Prescher G, Bornfeld N, Hirche H, et al.: Prognostic implications of monosomy 3 in uveal melanoma. Lancet 1996, 347:1222-1225.
    • (1996) Lancet , vol.347 , pp. 1222-1225
    • Prescher, G.1    Bornfeld, N.2    Hirche, H.3
  • 20
    • 5644251671 scopus 로고    scopus 로고
    • Gene expression profiling in uveal melanoma reveals two molecular classes and predicts metastatic death
    • Onken MD, Worley LA, Ehlers JP, Harbour JW: Gene expression profiling in uveal melanoma reveals two molecular classes and predicts metastatic death. Cancer Res 2004, 64:7205-7209.
    • (2004) Cancer Res , vol.64 , pp. 7205-7209
    • Onken, M.D.1    Worley, L.A.2    Ehlers, J.P.3    Harbour, J.W.4
  • 21
    • 33646405726 scopus 로고    scopus 로고
    • Functional gene expression analysis uncovers phenotypic switch in aggressive uveal melanomas
    • Onken MD, Ehlers JP, Worley LA, et al.: Functional gene expression analysis uncovers phenotypic switch in aggressive uveal melanomas. Cancer Res 2006, 66:4602-4609.
    • (2006) Cancer Res , vol.66 , pp. 4602-4609
    • Onken, M.D.1    Ehlers, J.P.2    Worley, L.A.3
  • 22
    • 36049030601 scopus 로고    scopus 로고
    • Expression of Wnt5a and its downstream effector beta-catenin in uveal melanoma
    • Zuidervaart W, Pavey S, van Nieuwpoort FA, et al.: Expression of Wnt5a and its downstream effector beta-catenin in uveal melanoma. Melanoma Res 2007, 17:380-386.
    • (2007) Melanoma Res , vol.17 , pp. 380-386
    • Zuidervaart, W.1    Pavey, S.2    van Nieuwpoort, F.A.3
  • 23
    • 33644873740 scopus 로고    scopus 로고
    • Metastatic uveal melanoma therapy: Current options
    • Bedikian AY: Metastatic uvealCmelanoma therapy: current options. Int Ophthalmol Clin 2006, 46:151-166.
    • (2006) Int Ophthalmol Clin , vol.46 , pp. 151-166
    • Bedikian, A.Y.1
  • 24
    • 0028853939 scopus 로고
    • Treatment of uveal melanoma metastatic to the liver: A review of the M.D. Anderson Cancer Center experience and prognostic factors
    • Bedikian AY, Legha SS, Mavligit G, et al.: Treatment of uveal melanoma metastatic to the liver: A review of the M.D. Anderson Cancer Center experience and prognostic factors. Cancer 1995, 76:1665-1670.
    • (1995) Cancer , vol.76 , pp. 1665-1670
    • Bedikian, A.Y.1    Legha, S.S.2    Mavligit, G.3
  • 25
    • 0034307203 scopus 로고    scopus 로고
    • Protracted survival after resection of metastatic uveal melanoma
    • Aoyama T, Mastrangelo MJ, Berd D, et al.: Protracted survival after resection of metastatic uveal melanoma. Cancer 2000, 89:1561-1568.
    • (2000) Cancer , vol.89 , pp. 1561-1568
    • Aoyama, T.1    Mastrangelo, M.J.2    Berd, D.3
  • 26
    • 17144438510 scopus 로고    scopus 로고
    • Treatment of ocular melanoma metastatic to the liver by hepatic arterial chemotherapy
    • Leyvraz S, Spataro V, Bauer J, et al.: Treatment of ocular melanoma metastatic to the liver by hepatic arterial chemotherapy. J Clin Oncol 1997, 15:2589-2595.
    • (1997) J Clin Oncol , vol.15 , pp. 2589-2595
    • Leyvraz, S.1    Spataro, V.2    Bauer, J.3
  • 27
    • 0028352232 scopus 로고
    • Intra-arterial hepatic carboplatin-based chemotherapy for ocular melanoma metastatic to the liver. Report of a phase II study
    • Cantore M, Fiorentini G, Aitini E, et al.: Intra-arterial hepatic carboplatin-based chemotherapy for ocular melanoma metastatic to the liver. Report of a phase II study. Tumori 1994, 80:37-39.
    • (1994) Tumori , vol.80 , pp. 37-39
    • Cantore, M.1    Fiorentini, G.2    Aitini, E.3
  • 28
    • 0033875498 scopus 로고    scopus 로고
    • A phase I-II study of isolated hepatic perfusion using melphalan with or without tumor necrosis factor for patients with ocular melanoma metastatic to liver
    • Alexander HR, Libutti SK, Bartlett DL, et al.: A phase I-II study of isolated hepatic perfusion using melphalan with or without tumor necrosis factor for patients with ocular melanoma metastatic to liver. Clin Cancer Res 2000, 6:3062-3070.
    • (2000) Clin Cancer Res , vol.6 , pp. 3062-3070
    • Alexander, H.R.1    Libutti, S.K.2    Bartlett, D.L.3
  • 29
    • 0023687302 scopus 로고
    • Regression of ocular melanoma metastatic to the liver after hepatic arterial chemoembolization with cisplatin and polyvinyl sponge
    • Mavligit GM, Charnsangavej C, Carrasco CH, et al.: Regression of ocular melanoma metastatic to the liver after hepatic arterial chemoembolization with cisplatin and polyvinyl sponge. JAMA 1988, 260:974-976.
    • (1988) JAMA , vol.260 , pp. 974-976
    • Mavligit, G.M.1    Charnsangavej, C.2    Carrasco, C.H.3
  • 30
    • 23744445248 scopus 로고    scopus 로고
    • Chemoembolization of the hepatic artery with BCNU for metastatic uveal melanoma: Results of a phase II study
    • Patel K, Sullivan K, Berd D, et al.: Chemoembolization of the hepatic artery with BCNU for metastatic uveal melanoma: Results of a phase II study. Melanoma Res 2005, 15:297-304.
    • (2005) Melanoma Res , vol.15 , pp. 297-304
    • Patel, K.1    Sullivan, K.2    Berd, D.3
  • 31
    • 56749158015 scopus 로고    scopus 로고
    • Immunoembolization of malignant liver tumors using granulocyte-macrophage colony-stimulating factor (GM-CSF, Ssargramostim): A novel treatment for uveal melanoma patients with hepatic metastases
    • [In press]
    • Sato T, Eschelman DJ, Gonsalves CF, et al.: Immunoembolization of malignant liver tumors using granulocyte-macrophage colony-stimulating factor (GM-CSF, Ssargramostim): A novel treatment for uveal melanoma patients with hepatic metastases. J Clin Oncol 2008 [In press].
    • (2008) J Clin Oncol
    • Sato, T.1    Eschelman, D.J.2    Gonsalves, C.F.3
  • 32
    • 58649113834 scopus 로고    scopus 로고
    • Treatment of uveal melanoma liver metastases using Y-90 SIR-Spheres: Imaging and clinical response
    • [abstract 128]
    • Gonsalves CF, Sullivan K, Eschelman DJ, et al.: Treatment of uveal melanoma liver metastases using Y-90 SIR-Spheres: Imaging and clinical response [abstract 128]. J Vasc Interv Radiol 2008, 19:S50.
    • (2008) J Vasc Interv Radiol , vol.19
    • Gonsalves, C.F.1    Sullivan, K.2    Eschelman, D.J.3
  • 33
    • 0026793058 scopus 로고
    • Progression of human cutaneous melanoma is associated with loss of expression of c-kit proto-oncogene receptor
    • Natali PG, Nicotra MR, Winkler AB, et al.: Progression of human cutaneous melanoma is associated with loss of expression of c-kit proto-oncogene receptor. Int J Cancer 1992, 52:197-201.
    • (1992) Int J Cancer , vol.52 , pp. 197-201
    • Natali, P.G.1    Nicotra, M.R.2    Winkler, A.B.3
  • 34
    • 0030813188 scopus 로고    scopus 로고
    • Molecular mechanisms of melanoma metastasis
    • Bar-Eli M: Molecular mechanisms of melanoma metastasis. J Cell Physiol 1997, 173:275-278.
    • (1997) J Cell Physiol , vol.173 , pp. 275-278
    • Bar-Eli, M.1
  • 35
    • 9144267709 scopus 로고    scopus 로고
    • Sequence analysis and high-throughput immunohistochemical profiling of KIT (CD 117) expression in uveal melanoma using tissue microarrays
    • Pache M, Glatz K, Bosch D, et al.: Sequence analysis and high-throughput immunohistochemical profiling of KIT (CD 117) expression in uveal melanoma using tissue microarrays. Virchows Arch 2003, 443:741-744.
    • (2003) Virchows Arch , vol.443 , pp. 741-744
    • Pache, M.1    Glatz, K.2    Bosch, D.3
  • 36
    • 0038580772 scopus 로고    scopus 로고
    • Expression of the c-kit receptor in choroidal melanomas
    • Mouriaux F, Kherrouche Z, Maurage CA, et al.: Expression of the c-kit receptor in choroidal melanomas. Melanoma Res 2003, 13:161-166.
    • (2003) Melanoma Res , vol.13 , pp. 161-166
    • Mouriaux, F.1    Kherrouche, Z.2    Maurage, C.A.3
  • 37
    • 0034769738 scopus 로고    scopus 로고
    • Implication of stem cell factor in the proliferation of choroidal melanocytes
    • Mouriaux F, Chahud F, Maurage CA, et al.: Implication of stem cell factor in the proliferation of choroidal melanocytes. Exp Eye Res 2001, 73:151-157.
    • (2001) Exp Eye Res , vol.73 , pp. 151-157
    • Mouriaux, F.1    Chahud, F.2    Maurage, C.A.3
  • 38
    • 3843116637 scopus 로고    scopus 로고
    • Roles of stem cell factor/c-Kit and effects of Glivec/STI571 in human uveal melanoma cell tumorigenesis
    • Lefevre G, Glotin AL, Calipel A, et al.: Roles of stem cell factor/c-Kit and effects of Glivec/STI571 in human uveal melanoma cell tumorigenesis. J Biol Chem 2004, 279:31769-31779.
    • (2004) J Biol Chem , vol.279 , pp. 31769-31779
    • Lefevre, G.1    Glotin, A.L.2    Calipel, A.3
  • 39
    • 58649119814 scopus 로고    scopus 로고
    • A pilot study using sunitinib malate as therapy in patients with stage IV uveal melanoma
    • [abstract 9047]
    • Chan KR, Gundala S, Laudadio M, et al.: A pilot study using sunitinib malate as therapy in patients with stage IV uveal melanoma [abstract 9047]. J Clin Oncol 2008, 26(15S):494s.
    • (2008) J Clin Oncol , vol.26 , Issue.15 S
    • Chan, K.R.1    Gundala, S.2    Laudadio, M.3
  • 40
    • 33947311526 scopus 로고    scopus 로고
    • Expression of epidermal growth factor receptor, ezrin, hepatocyte growth factor, and c-Met in uveal melanoma: An immunohistochemical study
    • Mallikarjuna K, Pushparaj V, Biswas J, et al.: Expression of epidermal growth factor receptor, ezrin, hepatocyte growth factor, and c-Met in uveal melanoma: An immunohistochemical study. Curr Eye Res 2007, 32:281-290.
    • (2007) Curr Eye Res , vol.32 , pp. 281-290
    • Mallikarjuna, K.1    Pushparaj, V.2    Biswas, J.3
  • 41
    • 33846999668 scopus 로고    scopus 로고
    • Expression and migratory analysis of 5 human uveal melanoma cell lines for CXCL12, CXCL8, CXCL1, and HGF
    • Di Cesare S, Marshall JC, Logan P, et al.: Expression and migratory analysis of 5 human uveal melanoma cell lines for CXCL12, CXCL8, CXCL1, and HGF. J Carcinog 2007, 6:2.
    • (2007) J Carcinog , vol.6 , pp. 2
    • Di Cesare, S.1    Marshall, J.C.2    Logan, P.3
  • 42
    • 33745697763 scopus 로고    scopus 로고
    • Targeting the c-Met signaling pathway in cancer
    • Peruzzi B, Bottaro DP: Targeting the c-Met signaling pathway in cancer. Clin Cancer Res 2006, 12:3657-3660.
    • (2006) Clin Cancer Res , vol.12 , pp. 3657-3660
    • Peruzzi, B.1    Bottaro, D.P.2
  • 43
    • 33644815365 scopus 로고    scopus 로고
    • Receptors for the liver synthesized growth factors IGF-1 and HGF/SF in uveal melanoma: Intercorrelation and prognostic implications
    • Economou MA, All-Ericsson C, Bykov V, et al.: Receptors for the liver synthesized growth factors IGF-1 and HGF/SF in uveal melanoma: intercorrelation and prognostic implications. Invest Ophthalmol Vis Sci 2005, 46:4372-4375.
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , pp. 4372-4375
    • Economou, M.A.1    All-Ericsson, C.2    Bykov, V.3
  • 44
    • 0036138625 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 receptor in uveal melanoma: A predictor for metastatic disease and a potential therapeutic target
    • All-Ericsson C, Girnita L, Seregard S, et al.: Insulin-like growth factor-1 receptor in uveal melanoma: A predictor for metastatic disease and a potential therapeutic target. Invest Ophthalmol Vis Sci 2002, 43:1-8.
    • (2002) Invest Ophthalmol Vis Sci , vol.43 , pp. 1-8
    • All-Ericsson, C.1    Girnita, L.2    Seregard, S.3
  • 45
    • 33750369197 scopus 로고    scopus 로고
    • Insulin-like growth factor-I axis as a pathway for cancer chemoprevention
    • Adhami VM, Afaq F, Mukhtar H: Insulin-like growth factor-I axis as a pathway for cancer chemoprevention. Clin Cancer Res 2006, 12:5611-5614.
    • (2006) Clin Cancer Res , vol.12 , pp. 5611-5614
    • Adhami, V.M.1    Afaq, F.2    Mukhtar, H.3
  • 46
    • 33644751770 scopus 로고    scopus 로고
    • The insulin-like growth factor-I receptor inhibitor picropodophyllin causes tumor regression and attenuates mechanisms involved in invasion of uveal melanoma cells
    • Girnita A, All-Ericsson C, Economou MA, et al.: The insulin-like growth factor-I receptor inhibitor picropodophyllin causes tumor regression and attenuates mechanisms involved in invasion of uveal melanoma cells. Clin Cancer Res 2006, 12:1383-1391.
    • (2006) Clin Cancer Res , vol.12 , pp. 1383-1391
    • Girnita, A.1    All-Ericsson, C.2    Economou, M.A.3
  • 47
    • 33644822256 scopus 로고    scopus 로고
    • High frequency of submicroscopic hemizygous deletion is a major mechanism of loss of expression of PTEN in uveal melanoma
    • Abdel-Rahman MH, Yang Y, Zhou XP, et al.: High frequency of submicroscopic hemizygous deletion is a major mechanism of loss of expression of PTEN in uveal melanoma. J Clin Oncol 2006, 24:288-295.
    • (2006) J Clin Oncol , vol.24 , pp. 288-295
    • Abdel-Rahman, M.H.1    Yang, Y.2    Zhou, X.P.3
  • 48
    • 23744472959 scopus 로고    scopus 로고
    • Immunohistochemical expression of phospho-Akt in uveal melanoma
    • Saraiva VS, Caissie AL, Segal L, et al.: Immunohistochemical expression of phospho-Akt in uveal melanoma. Melanoma Res 2005, 15:245-250.
    • (2005) Melanoma Res , vol.15 , pp. 245-250
    • Saraiva, V.S.1    Caissie, A.L.2    Segal, L.3
  • 49
    • 32944465388 scopus 로고    scopus 로고
    • Handicapping the race to develop inhibitors of the phosphoinositide 3-kinase/Akt/mammalian target of rapamycin pathway
    • Granville CA, Memmott RM, Gills JJ, et al.: Handicapping the race to develop inhibitors of the phosphoinositide 3-kinase/Akt/mammalian target of rapamycin pathway. Clin Cancer Res 2006, 12(3 Pt 1):679-689.
    • (2006) Clin Cancer Res , vol.12 , Issue.3 PART 1 , pp. 679-689
    • Granville, C.A.1    Memmott, R.M.2    Gills, J.J.3
  • 50
    • 23844476134 scopus 로고    scopus 로고
    • CCI-779 in metastatic melanoma: A phase II trial of the California Cancer Consortium
    • Margolin K, Longmate J, Baratta T, et al.: CCI-779 in metastatic melanoma: A phase II trial of the California Cancer Consortium. Cancer 2005, 104:1045-1048.
    • (2005) Cancer , vol.104 , pp. 1045-1048
    • Margolin, K.1    Longmate, J.2    Baratta, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.