Batf3 and Id2 have a synergistic effect on Irf8-directed classical CD8α+ dendritic cell development

Journal of Immunology

Volumn 191, Issue 12, 2013, Pages 5993-6001

  Jaiswal, Hemant ^a   Kaushik, Monika ^a   Sougrat, Rachid ^b   Gupta, Monica ^c   Dey, Anup ^c   Verma, Rohit ^a   Ozato, Keiko ^c   Tailor, Prafullakumar ^a  

^a NATIONAL INSTITUTE OF IMMUNOLOGY   (India)

^b KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Saudi Arabia)

^c EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INHIBITOR OF DIFFERENTIATION 2; INTERFERON; INTERFERON CONSENSUS SEQUENCE BINDING PROTEIN; INTERLEUKIN 12P40; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR BATF3; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; CD8+ T LYMPHOCYTE; CD8ALPHA+ DENDRITIC CELL; CELL FUNCTION; CELL MATURATION; CONTROLLED STUDY; DENDRITIC CELL; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PLASMACYTOID DENDRITIC CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; STEM CELL;

EID: 84890394146     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1203541     Document Type: Article

References (57)

1. Steinman, R. M., and J. Idoyaga. 2010. Features of the dendritic cell lineage. Immunol. Rev. 234: 5-17.
2. Belz, G. T., and S. L. Nutt. 2012. Transcriptional programming of the dendritic cell network. Nat. Rev. Immunol. 12: 101-113.
3. Shortman, K., and Y.-J. Liu. 2002. Mouse and human dendritic cell subtypes. Nat. Rev. Immunol. 2: 151-161.
4. Geissmann, F., M. G. Manz, S. Jung, M. H. Sieweke, M. Merad, and K. Ley. 2010. Development of monocytes, macrophages, and dendritic cells. Science 327: 656-661.
5. Robbins, S. H., T. Walzer, D. Dembélé, C. Thibault, A. Defays, G. Bessou, H. Xu, E. Vivier, M. Sellars, P. Pierre, et al. 2008. Novel insights into the relationships between dendritic cell subsets in human and mouse revealed by genome-wide expression profiling. Genome Biol. 9: R17.
6. Asselin-Paturel, C., and G. Trinchieri. 2005. Production of type I interferons: plasmacytoid dendritic cells and beyond. J. Exp. Med. 202: 461-465.
7. Villadangos, J. A., and L. Young. 2008. Antigen-presentation properties of plasmacytoid dendritic cells. Immunity 29: 352-361.
8. Siegal, F. P., N. Kadowaki, M. Shodell, P. A. Fitzgerald-Bocarsly, K. Shah, S. Ho, S. Antonenko, and Y.-J. Liu. 1999. The nature of the principal type 1 interferon-producing cells in human blood. Science 284: 1835-1837.
9. + dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens. J. Exp. Med. 207: 1247-1260.
10. + dendritic cells. J. Exp. Med. 207: 1261-1271.
11. + dendritic cells. J. Exp. Med. 207: 1283-1292.
12. + dendritic cells. J. Exp. Med. 207: 1273-1281.
13. + dendritic cells. J. Exp. Med. 207: 1131-1134.
14. Merad, M., and F. Ginhoux. 2007. Dendritic cell genealogy: a new stem or just another branch? Nat. Immunol. 8: 1199-1201.
15. + plasmacytoid and conventional dendritic cell progenitors in mouse bone marrow. Nat. Immunol. 8: 1207-1216.
16. Naik, S. H., P. Sathe, H.-Y. Park, D. Metcalf, A. I. Proietto, A. Dakic, S. Carotta, M. O'Keeffe, M. Bahlo, A. Papenfuss, et al. 2007. Development of plasmacytoid and conventional dendritic cell subtypes from single precursor cells derived in vitro and in vivo. Nat. Immunol. 8: 1217-1226.
17. Gilliet, M., A. Boonstra, C. Paturel, S. Antonenko, X.-L. Xu, G. Trinchieri, A. O'Garra, and Y.-J. Liu. 2002. The development of murine plasmacytoid dendritic cell precursors is differentially regulated by FLT3-ligand and granulocyte/macrophage colony-stimulating factor. J. Exp. Med. 195: 953-958.
18. Tamura, T., P. Tailor, K. Yamaoka, H. J. Kong, H. Tsujimura, J. J. O'Shea, H. Singh, and K. Ozato. 2005. IFN regulatory factor-4 and -8 govern dendritic cell subset development and their functional diversity. J. Immunol. 174: 2573-2581.
19. Fancke, B., M. Suter, H. Hochrein, and M. O'Keeffe. 2008. M-CSF: a novel plasmacytoid and conventional dendritic cell poietin. Blood 111: 150-159.
20. Esashi, E., Y.-H. Wang, O. Perng, X.-F. Qin, Y.-J. Liu, and S. S. Watowich. 2008. The signal transducer STAT5 inhibits plasmacytoid dendritic cell development by suppressing transcription factor IRF8. Immunity 28: 509-520.
21. +) dendritic cells. J. Exp. Med. 196: 1415-1425.
22. - dendritic cell development. Proc. Natl. Acad. Sci. USA 101: 8981-8986.
23. Tailor, P., T. Tamura, H. C. Morse, III, and K. Ozato. 2008. The BXH2 mutation in IRF8 differentially impairs dendritic cell subset development in the mouse. Blood 111: 1942-1945.
24. Honda, K., T. Mizutani, and T. Taniguchi. 2004. Negative regulation of IFN-α/β signaling by IFN regulatory factor 2 for homeostatic development of dendritic cells. Proc. Natl. Acad. Sci. USA 101: 2416-2421.
25. Gabriele, L., A. Fragale, P. Borghi, P. Sestili, E. Stellacci, M. Venditti, G. Schiavoni, M. Sanchez, F. Belardelli, and A. Battistini. 2006. IRF-1 deficiency skews the differentiation of dendritic cells toward plasmacytoid and tolerogenic features. J. Leukoc. Biol. 80: 1500-1511.
26. Cisse, B., M. L. Caton, M. Lehner, T. Maeda, S. Scheu, R. Locksley, D. Holmberg, C. Zweier, N. S. den Hollander, S. G. Kant, et al. 2008. Transcription factor E2-2 is an essential and specific regulator of plasmacytoid dendritic cell development. Cell 135: 37-48.
27. Hacker, C., R. D. Kirsch, X.-S. Ju, T. Hieronymus, T. C. Gust, C. Kuhl, T. Jorgas, S. M. Kurz, S. Rose-John, Y. Yokota, and M. Zenke. 2003. Transcriptional profiling identifies Id2 function in dendritic cell development. Nat. Immunol. 4: 380-386.
28. +) stem cells into predendritic cell (pre-DC)2 but not into pre-DC1. Evidence for a lymphoid origin of pre-DC2. J. Exp. Med. 192: 1775-1784.
29. Schotte, R., M. Nagasawa, K. Weijer, H. Spits, and B. Blom. 2004. The ETS transcription factor Spi-B is required for human plasmacytoid dendritic cell development. J. Exp. Med. 200: 1503-1509.
30. Allman, D., M. Dalod, C. Asselin-Paturel, T. Delale, S. H. Robbins, G. Trinchieri, C. A. Biron, P. Kastner, and S. Chan. 2006. Ikaros is required for plasmacytoid dendritic cell differentiation. Blood 108: 4025-4034.
31. + DCs. J. Exp. Med. 206: 3115-3130.
32. + conventional dendritic cells. J. Exp. Med. 207: 823-836.
33. Tussiwand, R., W.-L. Lee, T. L. Murphy, M. Mashayekhi, K. C. Wumesh, J. C. Albring, A. T. Satpathy, J. A. Rotondo, B. T. Edelson, N. M. Kretzer, et al. 2012. Compensatory dendritic cell development mediated by BATF-IRF interactions. Nature 490: 502-507.
34. + dendritic cell development. Blood 117: 6193-6197.
35. Satpathy, A. T., W. Kc, J. C. Albring, B. T. Edelson, N. M. Kretzer, D. Bhattacharya, T. L. Murphy, and K. M. Murphy. 2012. Zbtb46 expression distinguishes classical dendritic cells and their committed progenitors from other immune lineages. J. Exp. Med. 209: 1135-1152.
36. Meredith, M. M., K. Liu, A. O. Kamphorst, J. Idoyaga, A. Yamane, P. Guermonprez, S. Rihn, K.-H. Yao, I. T. Silva, T. Y. Oliveira, et al. 2012. Zinc finger transcription factor zDC is a negative regulator required to prevent activation of classical dendritic cells in the steady state. J. Exp. Med. 209: 1583-1593.
37. Tsujimura, H., T. Tamura, C. Gongora, J. Aliberti, C. Reis e Sousa, A. Sher, and K. Ozato. 2003. ICSBP/IRF-8 retrovirus transduction rescues dendritic cell development in vitro. Blood 101: 961-969.
38. Tsujimura, H., T. Tamura, and K. Ozato. 2003. Cutting edge: IFN consensus sequence binding protein/IFN regulatory factor 8 drives the development of type I IFN-producing plasmacytoid dendritic cells. J. Immunol. 170: 1131-1135.
39. Tailor, P., T. Tamura, H. J. Kong, T. Kubota, M. Kubota, P. Borghi, L. Gabriele, and K. Ozato. 2007. The feedback phase of type I interferon induction in dendritic cells requires interferon regulatory factor 8. Immunity 27: 228-239.
40. Tamura, T., P. Thotakura, T. S. Tanaka, M. S. H. Ko, and K. Ozato. 2005. Identification of target genes and a unique cis element regulated by IRF-8 in developing macrophages. Blood 106: 1938-1947.
41. Curry, J. M., T. D. Eubank, R. D. Roberts, Y. Wang, N. Pore, A. Maity, and C. B. Marsh. 2008. M-CSF signals through the MAPK/ERK pathway via Sp1 to induce VEGF production and induces angiogenesis in vivo. PLoS ONE 3: e3405.
42. Tsujimura, H., T. Tamura, H. J. Kong, A. Nishiyama, K. J. Ishii, D. M. Klinman, and K. Ozato. 2004. Toll-like receptor 9 signaling activates NF-kappaB through IFN regulatory factor-8/IFN consensus sequence binding protein in dendritic cells. J. Immunol. 172: 6820-6827.
43. Tamura, T., T. Nagamura-Inoue, Z. Shmeltzer, T. Kuwata, and K. Ozato. 2000. ICSBP directs bipotential myeloid progenitor cells to differentiate into mature macrophages. Immunity 13: 155-165.
44. Schmidt, M., J. Bies, T. Tamura, K. Ozato, and L. Wolff. 2004. The interferon regulatory factor ICSBP/IRF-8 in combination with PU.1 up-regulates expression of tumor suppressor p15(Ink4b) in murine myeloid cells. Blood 103: 4142-4149.
45. Tamura, T., H. J. Kong, C. Tunyaplin, H. Tsujimura, K. Calame, and K. Ozato. 2003. ICSBP/IRF-8 inhibits mitogenic activity of p210 Bcr/Abl in differentiating myeloid progenitor cells. Blood 102: 4547-4554.
46. Nardi, V., O. Naveiras, M. Azam, and G. Q. Daley. 2009. ICSBP-mediated immune protection against BCR-ABL-induced leukemia requires the CCL6 and CCL9 chemokines. Blood 113: 3813-3820.
47. Hao, S. X., and R. Ren. 2000. Expression of interferon consensus sequence binding protein (ICSBP) is downregulated in Bcr-Abl-induced murine chronic myelogenous leukemia-like disease, and forced coexpression of ICSBP inhibits Bcr-Abl-induced myeloproliferative disorder. Mol. Cell. Biol. 20: 1149-1161.
48. Yang, D., M. Thangaraju, K. Greeneltch, D. D. Browning, P. V. Schoenlein, T. Tamura, K. Ozato, V. Ganapathy, S. I. Abrams, and K. Liu. 2007. Repression of IFN regulatory factor 8 by DNA methylation is a molecular determinant of apoptotic resistance and metastatic phenotype in metastatic tumor cells. Cancer Res. 67: 3301-3309.
49. Schönheit, J., C. Kuhl, M. L. Gebhardt, F. F. Klett, P. Riemke, M. Scheller, G. Huang, R. Naumann, A. Leutz, C. Stocking, et al. 2013. PU.1 level-directed chromatin structure remodeling at the Irf8 gene drives dendritic cell commitment. Cell Rep 3: 1617-1628.
50. Shen, Z., G. Reznikoff, G. Dranoff, and K. L. Rock. 1997. Cloned dendritic cells can present exogenous antigens on both MHC class I and class II molecules. J. Immunol. 158: 2723-2730.
51. Maeda, T., K. Murata, T. Fukushima, K. Sugahara, K. Tsuruda, M. Anami, Y. Onimaru, K. Tsukasaki, M. Tomonaga, R. Moriuchi, et al. 2005. A novel plasmacytoid dendritic cell line, CAL-1, established from a patient with blastic natural killer cell lymphoma. Int. J. Hematol. 81: 148-154.
52. Kammertoens, T., R. Willebrand, B. Erdmann, L. Li, Y. Li, B. Engels, W. Uckert, and T. Blankenstein. 2005. CY15, a malignant histiocytic tumor that is phenotypically similar to immature dendritic cells. Cancer Res. 65: 2560-2564.
53. + dendritic cells. Blood 101: 305-310.
54. Turcotte, K., S. Gauthier, D. Malo, M. Tam, M. M. Stevenson, and P. Gros. 2007. Icsbp1/IRF-8 is required for innate and adaptive immune responses against intracellular pathogens. J. Immunol. 179: 2467-2476.
55. + dendritic cells in cytotoxic T cell immunity. Science 322: 1097-1100.
56. + dendritic cell lineages. EMBO J. 30: 2690-2704.
57. + dendritic cells: master regulators of tolerance? Trends Immunol. 32: 412-419.