Amyloid β peptide cleavage by kallikrein 7 attenuates fibril growth and rescues neurons from Aβ-mediated toxicity in vitro

Biological Chemistry

Volumn 395, Issue 1, 2014, Pages 109-118

  Shropshire, Tyler D ^a   Reifert, Jack ^a,b   Rajagopalan, Sridharan ^c   Baker, David ^c   Feinstein, Stuart C ^b   Daugherty, Patrick S ^a,b  

^a University of California   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Alzheimer disease; cation ; clearance; protease; substrate

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; INSULINASE; STRATUM CORNEUM CHYMOTRYPTIC ENZYME;

ANIMAL CELL; ARTICLE; BRAIN NERVE CELL; CELL DEATH; CELL VIABILITY; EMBRYO; ENZYME SPECIFICITY; HIPPOCAMPUS; HYDROPHOBICITY; IN VITRO STUDY; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN MOTIF; RAT;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; AMYLOID BETA-PEPTIDES; ANIMALS; HUMANS; KALLIKREINS; MODELS, MOLECULAR; NEURONS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84890378967     PISSN: 14316730     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/hsz-2013-0230     Document Type: Article

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