Stress and withdrawal from d-amphetamine alter 5-HT2A receptor mRNA expression in the prefrontal cortex

Neuroscience Letters

Volumn 559, Issue , 2014, Pages 44-49

  Murray, Ryan C ^a   Hebbard, John C ^a   Logan, Anna S ^a   Vanchipurakel, Golda A ^a   Gilbert, Yamiece E ^a   Horner, Kristen A ^a  

^a MERCER UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

5 Hydroxytryptamine; Forced swim; Psychostimulant; Withdrawal

Indexed keywords

AMPHETAMINE; MESSENGER RNA; SEROTONIN 2A RECEPTOR;

ANTERIOR CINGULATE; ARTICLE; COGNITIVE DEFECT; DRUG SEEKING BEHAVIOR; HISTOCHEMISTRY; IMMOBILITY; IN SITU HYBRIDIZATION; ORBITAL CORTEX; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; STRESS; WHITE MATTER; WITHDRAWAL SYNDROME;

5-HT; 5-HT(2A)R; 5-HYDROXYTRYPTAMINE; ACC; AMPH; ANALYSIS OF VARIANCE; ANOVA; ANTERIOR CINGULATE CORTEX; D-AMPHETAMINE; FORCED SWIM; FORCED SWIM TEST; FST; LATERAL ORBITOFRONTAL CORTEX; LOFC; MAJOR DEPRESSIVE DISORDER; MDD; MEDIAL ORBITOFRONTAL CORTEX; MOFC; NAC; NUCLEUS ACCUMBENS; PFC; PREFRONTAL CORTEX; PRELIMBIC CORTEX; PRL; PSYCHOSTIMULANT; SALINE-SODIUM CITRATE; SEROTONIN; SEROTONIN SUBTYPE 2A RECEPTOR; SSC; VENTRAL ORBITOFRONTAL CORTEX; VENTRAL TEGMENTAL AREA; VOFC; VTA; WITHDRAWAL;

AMPHETAMINE-RELATED DISORDERS; ANIMALS; DEXTROAMPHETAMINE; GENE EXPRESSION REGULATION; MALE; PREFRONTAL CORTEX; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, SEROTONIN, 5-HT2A; RNA, MESSENGER; STRESS, PSYCHOLOGICAL; SUBSTANCE WITHDRAWAL SYNDROME;

EID: 84890321355     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2013.11.028     Document Type: Article

References (42)

1. Aharonovich E., Hasin D.S., Brooks A.C., Liu X., Bisaga A., Nunes E.V. Cognitive deficits predict low treatment retention in cocaine-dependent patients. Drug Alcohol Depend. 2006, 81:313-322.
2. Barr A.M., Markou A. Psychostimulant withdrawal as an inducing condition in animal models of depression. Neurosci. Biobehav. Rev. 2005, 29:675-706.
3. Barr A.M., Markou A., Phillips A.G. A crash course on psychostimulant withdrawal as a model of depression. Trends Pharmacol. Sci. 2002, 23:475-482.
4. Shirayama Y., Ishida H., Iwata M., Hazama G.I., Kawahara R., Duman R.S. Stress increases dynorphin immunoreactivity in limbic brain regions and dynorphin antagonism produces antidepressant-like effects. J. Neurochem. 2004, 90:1258-1268.
5. Shaham Y., Erb S., Stewart J. Stress-induced relapse to heroin and cocaine seeking in rats: a review. Brain Res. Brain Res. Rev. 2000, 33:13-33.
6. Sinha R. How does stress increase risk of drug abuse and relapse?. Psychopharmacology 2001, 158:343-359.
7. Mann J.J., McBride P.A., Malone K.M., DeMeo M., Keilp J. Blunted serotonergic responsitivity in depressed patients. Neuropsychopharmacology 1995, 13:53-64.
8. Shelton R.C., Sanders-Bush E., Manier D.H., Lewis D.A. Elevated 5-HT 2A receptors in postmortem prefrontal cortex in major depression is associated with reduced activity of protein kinase A. Neuroscience 2009, 158:1406-1415.
9. Horner K.A., Gilbert Y.E., Noble E.S. Differential regulation of 5-HT2A receptor mRNA expression following withdrawal from a chronic escalating dose regimen of d-amphetamine. Brain Res. 2011, 1390:10-20.
10. Baumann M.H., Brockington A.M., Rothman R.B. Withdrawal from chronic cocaine enhances behavioral sensitivity to the 5-HT2/1C agonist DOI. Biol. Psychiatry 1993, 34:576-577.
11. Baumann M.H., Rothman R.B. Alterations in serotonergic responsiveness during cocaine withdrawal in rats: similarities to depression in humans. Biol. Psychiatry 1998, 44:578-591.
12. Carrasco G.A., Van de Kar L.D., Sullivan N.R., Landry M., Garcia F., Muma N.A., Battaglia G. Cocaine-mediated supersensitivity of 5-HT2A receptors in hypothalamic paraventricular nucleus is a withdrawal-induced phenomenon. Neuroscience 2006, 143:7-13.
13. Huang C.C., Liang Y-C., Lee C-C., Wu M-Y., Hsu K-S. Repeated cocaine administration decreases 5-HT2A receptor-mediated serotonergic enhancement of synaptic activity in rat medial prefrontal cortex. Neuropsychopharmacology 2009, 34:1979-1992.
14. Kalivas P.W., Volkow N.D. The neural basis of addiction: a pathology of motivation and choice. Am. J. Psychiatry 2005, 162:1403-1413.
15. Volkow N.D., Fowler J.S., Wang G.J., Hitzemann R., Logan J., Schlyer D.J., Dewey S.L., Wolf A.P. Decreased dopamine D2 receptor availability is associated with reduced frontal metabolism in cocaine abusers. Synapse 1993, 14:169-177.
16. Berendse H.W., Galis-de Graaf Y., Groenewegen H.J. Topographical organization and relationship with ventral striatal compartments of prefrontal corticostriatal projections in the rat. J. Comp. Neurol. 1992, 316:314-347.
17. Bortolozzi A., Díaz-Mataix L., Scorza M.C., Celada P., Artigas F. The activation of 5-HT2A receptors in prefrontal cortex enhances dopaminergic activity. J. Neurochem. 2005, 95:1597-1607.
18. Cami J., Farre M. Drug addiction. N. Engl. J. Med. 2003, 349:975-986.
19. Christie M.J., James L.B., Beart P.M. An excitant amino acid projection from the medial prefrontal cortex to the anterior part of nucleus accumbens in the rat. J. Neurochem. 1985, 45:477-482.
20. 2A receptors. Cereb. Cortex 2009, 19:1678-1686.
21. Miller E.K., Cohen J.D. An integrative theory of prefrontal cortex function. Annu. Rev. Neurosci. 2001, 24:167-202.
22. Cardinal R.N., Parkinson J.A., Hall J., Everitt B.J. Emotion and motivation: the role of the amygdala, ventral striatum, and prefrontal cortex. Neurosci. Biobehav. Rev. 2002, 26:321-352.
23. Heidbreder C.A., Groenewegen H.J. The medial prefrontal cortex in the rat: evidence for a dorso-ventral distinction based upon functional and anatomical characteristics. Neurosci. Biobehav. Rev. 2003, 27:555-579.
24. Morgane P.J., Galler J.R., Mokler D.J. A review of systems and networks of the limbic forebrain/limbic midbrain. Prog. Neurobiol. 2005, 75:143-160.
25. Buhot M.C. Serotonin receptors in cognitive behaviors. Curr. Opin. Neurobiol. 1997, 7:243-254.
26. Celada P., Puig M.V., Amargos-Bosch M., Adell A., Artigas F. The therapeutic role of 5-HT1A and 5-HT2A receptors in depression. J. Psychiatry Neurosci. 2004, 29:252-265.
27. Williams G.V., Rao S.G., Goldman-Rakic P.S. The physiological role of 5-HT2A receptors in working memory. J. Neurosci. 2002, 22:2843-2854.
28. Pace-Schott E.F., Morgan P.T., Malison R.T., Hart C.L., Edgar C., Walker M., Stickgold R. Cocaine users differ from normals on cognitive tasks which show poorer performance during drug abstinence. Am. J. Drug Alcohol Abuse 2008, 34:109-121.
29. Barr A.M., Fiorina D.F., Phillips A.G. Effects of withdrawal from an escalating dose schedule of d-amphetamine on sexual behavior of the male rat. Pharm. Biochem. Behav. 1999, 64:597-604.
30. Barr A.M., Phillips A.G. Withdrawal following repeated exposure to d-amphetamine decreases responding for a sucrose solution as measured by a progressive ratio schedule of reinforcement. Psychopharmacology 1999, 141:99-106.
31. Horner K.A., Noble E.N., Lauterbach E.C. Differential regulation of prodynorphin, c-fos and serotonin transporter mRNA during withdrawal from a chronic, escalating dose regimen of d-amphetamine. Synapse 2009, 63:257-268.
32. Kokkinidis L., Zacharko R.M., Anisman H. Amphetamine withdrawal: a behavioral evaluation. Life Sci. 1986, 38:1617-1623.
33. Detke M.J., Rickels M., Lucki I. Active behaviors in the rat forced swimming test differentially produced by serotonergic and noradrenergic antidepressants. Psychopharmacology (Berl.) 1995, 121:66-72.
34. Saltzman A.G., Morse B., Whitman M.M., Ivanshchenko Y., Jaye M., Felder S. Cloning of the human serotonin 5-HT2 and 5-HT1C receptor subtypes. Biochem. Biophys. Res. Commun. 1991, 181:1469-1478.
35. Paxinos G., Watson C. The Rat Brain in Sterotaxic Coordinates 2005, New York, NY, Elsevier Academic Press.
36. Schwanhausser B., Busse D., Li N., Dittmar G., Schuchhardt J., Wolf J., Chen W., Selbach M. Global quantification of mammalian gene expression control. Nature 2011, 473:337-342.
37. Tian Q., Stepaniants S.B., Mao M., Weng L., Feetham M.C., Doyle M.J., Yi E.C., Dai H., Thorsson V., Eng J., Goodlett D., Berger J.P., Gunter B., Linseley P.S., Stoughton R.B., Aebersold R., Collins S.J., Hanlon W.A., Hood L.E. Integrated genomic and proteomic analyses of gene expression in mammalian cells. Mol. Cell. Proteomics 2004, 3:960-969.
38. Vogel C., Abreu Rde S., Ko D., Le S.Y., Shapiro B.A., Burns S.C., Sandhu D., Boutz D.R., Marcotte E.M., Penalva L.O. Sequence signatures and mRNA concentration can explain two-thirds of protein abundance variation in a human cell line. Mol. Syst. Biol. 2010, 6:400.
39. Vogel C., Marcotte E.M. Insights into the regulation of protein abundance from proteomic and transcriptomic analyses. Nat Rev Genet 2012, 13:227-232.
40. Mihindou C., Guillem K., Navailles S., Vouillac C., Ahmed S.H. Discriminative inhibitory control of cocaine seeking involves the prelimbic prefrontal cortex. Biol. Psychiatry 2013, 73:271-279.
41. Di Chiara G. Nucleus accumbens shell and core dopamine: differential role in behavior and addiction. Behav. Brain Res. 2002, 137:75-114.
42. Volkow N.D., Fowler J.S., Wang G.J. The addicted human brain: insights from imaging studies. J. Clin. Invest. 2003, 111:1444-1451.