Focal targeting by human β-defensin 2 disrupts localized virulence factor assembly sites in Enterococcus faecalis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 50, 2013, Pages 20230-20235

  Kandaswamy, Kumaravel ^a,b   Liew, Tze Horng ^b   Wang, Charles Y ^b   Huston Warren, Emily ^c   Meyer Hoffert, Ulf ^d   Hultenby, Kjell ^e   Schröder, Jens M ^d   Caparon, Michael G ^c   Normark, Staffan ^f,g   Henriques Normark, Birgitta ^f,g   Hultgren, Scott J ^c   Kline, Kimberly A ^b  

^a NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^b NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^e Clinical Research Center   (Sweden)

^f KAROLINSKA INSTITUTE   (Sweden)

^g KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Focal localization; Immunofluorescence; Microscopy; MprF

Indexed keywords

BACTERIAL ENZYME; BETA DEFENSIN 2; LIPID; POLYPEPTIDE ANTIBIOTIC AGENT; PROTEIN SECA; SORTASE A; UNCLASSIFIED DRUG; VIRULENCE FACTOR;

ARTICLE; BACTERIAL CELL WALL; BACTERIAL VIRULENCE; CELL CYCLE; CONTROLLED STUDY; ENTEROCOCCUS FAECALIS; ENTROPY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; PROTEIN TARGETING; R FACTOR;

EID: 84890286129     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1319066110     Document Type: Article

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