메뉴 건너뛰기




Volumn 144, Issue 6, 2013, Pages 1923-1929

α1-antitrypsin deficiency: What has it ever done for us?

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ANTITRYPSIN; LEUKOCYTE ELASTASE;

EID: 84890275802     PISSN: 00123692     EISSN: 19313543     Source Type: Journal    
DOI: 10.1378/chest.13-1901     Document Type: Article
Times cited : (9)

References (81)
  • 1
    • 84907041622 scopus 로고
    • The electrophorectic alpha 1-globulin pattern of serum in alpha 1-antitrypsin deficiency
    • Laurell C, Eriksson S. The electrophorectic alpha 1-globulin pattern of serum in alpha 1-antitrypsin deficiency. Scand J Clin Lab Invest. 1963;15:132-140.
    • (1963) Scand J Clin Lab Invest , vol.15 , pp. 132-140
    • Laurell, C.1    Eriksson, S.2
  • 2
    • 0026954510 scopus 로고
    • Emphysema: The first two centuries - and beyond. A historical overview, with suggestions for future research: Part 1
    • Snider GL. Emphysema: the first two centuries - and beyond. A historical overview, with suggestions for future research: part 1. Am Rev Respir Dis. 1992;146(5 pt 1):1334-1344.
    • (1992) Am Rev Respir Dis , vol.146 , Issue.5 PART 1 , pp. 1334-1344
    • Snider, G.L.1
  • 3
    • 84890303240 scopus 로고
    • Introductory remarks
    • C. Mittman, ed. New York, NY: Academic Press
    • Briscoe WA. Introductory remarks. In: C. Mittman, ed. Pulmonary Emphysema and Proteolysis. New York, NY: Academic Press; 1972:3-5.
    • (1972) Pulmonary Emphysema and Proteolysis , pp. 3-5
    • Briscoe, W.A.1
  • 5
    • 0014783184 scopus 로고
    • Genetic and environmental determinants of chronic obstructive pulmonary disease
    • Larson RK, Barman ML, Kueppers F, Fudenberg HH. Genetic and environmental determinants of chronic obstructive pulmonary disease. Ann Intern Med. 1970;72(5):627-632.
    • (1970) Ann Intern Med , vol.72 , Issue.5 , pp. 627-632
    • Larson, R.K.1    Barman, M.L.2    Kueppers, F.3    Fudenberg, H.H.4
  • 6
    • 0017719147 scopus 로고
    • Familial prevalence of chronic obstructive pulmonary disease in a matched pair study
    • Kueppers F, Miller RD, Gordon H, Hepper NG, Offord K. Familial prevalence of chronic obstructive pulmonary disease in a matched pair study. Am J Med. 1977;63(3):336-342.
    • (1977) Am J Med , vol.63 , Issue.3 , pp. 336-342
    • Kueppers, F.1    Miller, R.D.2    Gordon, H.3    Hepper, N.G.4    Offord, K.5
  • 8
    • 0023148995 scopus 로고
    • Replacement therapy for alpha 1-antitrypsin deficiency associated with emphysema
    • Wewers MD, Casolaro MA, Sellers SE, et al. Replacement therapy for alpha 1-antitrypsin deficiency associated with emphysema. N Engl J Med. 1987;316(17):1055-1062.
    • (1987) N Engl J Med , vol.316 , Issue.17 , pp. 1055-1062
    • Wewers, M.D.1    Casolaro, M.A.2    Sellers, S.E.3
  • 9
    • 0034066328 scopus 로고    scopus 로고
    • Feasibility of a clinical trial of augmentation therapy for alpha(1)-antitrypsin deficiency
    • The Alpha 1-Antitrypsin Deficiency Registry Study Group
    • Schluchter MD, Stoller JK, Barker AF, et al. Feasibility of a clinical trial of augmentation therapy for alpha(1)-antitrypsin deficiency. The Alpha 1-Antitrypsin Deficiency Registry Study Group. Am J Respir Crit Care Med. 2000;161(3 pt 1):796-801.
    • (2000) Am J Respir Crit Care Med , vol.161 , Issue.3 PART 1 , pp. 796-801
    • Schluchter, M.D.1    Stoller, J.K.2    Barker, A.F.3
  • 10
    • 0023898432 scopus 로고
    • Molecular basis of alpha-1-antitrypsin deficiency
    • Brantly ML, Nukiwa T, Crystal RG. Molecular basis of alpha-1-antitrypsin deficiency. Am J Med. 1988;84(6A):13-31.
    • (1988) Am J Med , vol.84 , Issue.6 , pp. 13-31
    • Brantly, M.L.1    Nukiwa, T.2    Crystal, R.G.3
  • 11
    • 0026755363 scopus 로고
    • The mechanism of Z alpha 1-antitrypsin accumulation in the liver
    • Lomas DA, Evans DL, Finch JT, Carrell RW. The mechanism of Z alpha 1-antitrypsin accumulation in the liver. Nature. 1992;357(6379):605-607.
    • (1992) Nature , vol.357 , Issue.6379 , pp. 605-607
    • Lomas, D.A.1    Evans, D.L.2    Finch, J.T.3    Carrell, R.W.4
  • 12
    • 33645057629 scopus 로고    scopus 로고
    • Polymerisation underlies alpha1-antitrypsin deficiency, dementia and other serpinopathies
    • Lomas DA, Belorgey D, Mallya M, et al. Polymerisation underlies alpha1-antitrypsin deficiency, dementia and other serpinopathies. Front Biosci. 2004;9:2873-2891.
    • (2004) Front Biosci , vol.9 , pp. 2873-2891
    • Lomas, D.A.1    Belorgey, D.2    Mallya, M.3
  • 13
    • 35848929750 scopus 로고    scopus 로고
    • Small molecules block the polymerization of Z alpha1-antitrypsin and increase the clearance of intracellular aggregates
    • Mallya M, Phillips RL, Saldanha SA, et al. Small molecules block the polymerization of Z alpha1-antitrypsin and increase the clearance of intracellular aggregates. J Med Chem. 2007;50(22):5357-5363.
    • (2007) J Med Chem , vol.50 , Issue.22 , pp. 5357-5363
    • Mallya, M.1    Phillips, R.L.2    Saldanha, S.A.3
  • 14
    • 2642680855 scopus 로고    scopus 로고
    • Alpha 1-antitrypsin deficiency: Memorandum from a WHO meeting
    • Alpha 1-antitrypsin deficiency: memorandum from a WHO meeting. Bull World Health Organ. 1997;75(5):397-415.
    • (1997) Bull World Health Organ , vol.75 , Issue.5 , pp. 397-415
  • 15
    • 84875670108 scopus 로고    scopus 로고
    • Alpha-1 antitrypsin deficiency: The European experience
    • Stockley RA, Dirksen A, Stolk J. Alpha-1 antitrypsin deficiency: the European experience. COPD. 2013;10(suppl 1):50-53.
    • (2013) COPD , vol.10 , Issue.SUPPL. 1 , pp. 50-53
    • Stockley, R.A.1    Dirksen, A.2    Stolk, J.3
  • 16
    • 67649407825 scopus 로고    scopus 로고
    • Exploring the role of CT densitometry: A randomised study of augmentation therapy in alpha1-antitrypsin deficiency
    • Dirksen A, Piitulainen E, Parr DG, et al. Exploring the role of CT densitometry: a randomised study of augmentation therapy in alpha1-antitrypsin deficiency. Eur Respir J. 2009;33(6):1345-1353.
    • (2009) Eur Respir J , vol.33 , Issue.6 , pp. 1345-1353
    • Dirksen, A.1    Piitulainen, E.2    Parr, D.G.3
  • 17
    • 84864770563 scopus 로고    scopus 로고
    • Randomised controlled trial for emphysema with a selective agonist of the γ-type retinoic acid receptor
    • Stolk J, Stockley RA, Stoel BC, et al. Randomised controlled trial for emphysema with a selective agonist of the γ-type retinoic acid receptor. Eur Respir J. 2012;40(2):306-312.
    • (2012) Eur Respir J , vol.40 , Issue.2 , pp. 306-312
    • Stolk, J.1    Stockley, R.A.2    Stoel, B.C.3
  • 18
    • 65349089694 scopus 로고    scopus 로고
    • Phenotypic differences in alpha 1 antitrypsin-deficient sibling pairs may relate to genetic variation
    • Wood AM, Needham M, Simmonds MJ, Newby PR, Gough SC, Stockley RA. Phenotypic differences in alpha 1 antitrypsin-deficient sibling pairs may relate to genetic variation. COPD. 2008;5(6):353-359.
    • (2008) COPD , vol.5 , Issue.6 , pp. 353-359
    • Wood, A.M.1    Needham, M.2    Simmonds, M.J.3    Newby, P.R.4    Gough, S.C.5    Stockley, R.A.6
  • 19
    • 0034889702 scopus 로고    scopus 로고
    • Highresolution computed tomography scanning in α1-antitrypsin deficiency: Relationship to lung function and health status
    • Dowson LJ, Guest PJ, Hill SL, Holder RL, Stockley RA. Highresolution computed tomography scanning in α1-antitrypsin deficiency: relationship to lung function and health status. Eur Respir J. 2001;17(6):1097-1104.
    • (2001) Eur Respir J , vol.17 , Issue.6 , pp. 1097-1104
    • Dowson, L.J.1    Guest, P.J.2    Hill, S.L.3    Holder, R.L.4    Stockley, R.A.5
  • 20
    • 78649949010 scopus 로고    scopus 로고
    • Retinoid treatment of Emphysema in Patients on the Alpha-1 International Registry. The REPAIR study: Study design, methodology and quality control of study assessments
    • Stolk J, Cooper BG, Stoel B, et al. Retinoid treatment of Emphysema in Patients on the Alpha-1 International Registry. The REPAIR study: study design, methodology and quality control of study assessments. Ther Adv Respir Dis. 2010;4(6):319-332.
    • (2010) Ther Adv Respir Dis , vol.4 , Issue.6 , pp. 319-332
    • Stolk, J.1    Cooper, B.G.2    Stoel, B.3
  • 21
    • 0035891572 scopus 로고    scopus 로고
    • Longitudinal changes in physiological, radiological, and health status measurements in alpha(1)-antitrypsin deficiency and factors associated with decline
    • Dowson LJ, Guest PJ, Stockley RA. Longitudinal changes in physiological, radiological, and health status measurements in alpha(1)-antitrypsin deficiency and factors associated with decline. Am J Respir Crit Care Med. 2001;164(10 pt 1):1805-1809.
    • (2001) Am J Respir Crit Care Med , vol.164 , Issue.10 PART 1 , pp. 1805-1809
    • Dowson, L.J.1    Guest, P.J.2    Stockley, R.A.3
  • 23
    • 77955606635 scopus 로고    scopus 로고
    • Outdoor air pollution is associated with rapid decline of lung function in alpha-1-antitrypsin deficiency
    • Wood AM, Harrison RM, Semple S, Ayres JG, Stockley RA. Outdoor air pollution is associated with rapid decline of lung function in alpha-1-antitrypsin deficiency. Occup Environ Med. 2010;67(8):556-561.
    • (2010) Occup Environ Med , vol.67 , Issue.8 , pp. 556-561
    • Wood, A.M.1    Harrison, R.M.2    Semple, S.3    Ayres, J.G.4    Stockley, R.A.5
  • 24
    • 33745135090 scopus 로고    scopus 로고
    • Validation of computed tomographic lung densitometry for monitoring emphysema in α1-antitrypsin deficiency
    • Parr DG, Stoel BC, Stolk J, Stockley RA. Validation of computed tomographic lung densitometry for monitoring emphysema in α1-antitrypsin deficiency. Thorax. 2006;61(6):485-490.
    • (2006) Thorax , vol.61 , Issue.6 , pp. 485-490
    • Parr, D.G.1    Stoel, B.C.2    Stolk, J.3    Stockley, R.A.4
  • 25
    • 9644295576 scopus 로고    scopus 로고
    • Pattern of emphysema distribution in a 1-antitrypsin deficiency influences lung function impairment
    • Parr DG, Stoel BC, Stolk J, Stockley RA. Pattern of emphysema distribution in a 1-antitrypsin deficiency influences lung function impairment. Am J Respir Crit Care Med. 2004;170(11):1172-1178.
    • (2004) Am J Respir Crit Care Med , vol.170 , Issue.11 , pp. 1172-1178
    • Parr, D.G.1    Stoel, B.C.2    Stolk, J.3    Stockley, R.A.4
  • 26
    • 35448986121 scopus 로고    scopus 로고
    • Radiologic and clinical features of COPD patients with discordant pulmonary physiology: Lessons from alpha1-antitrypsin deficiency
    • Holme J, Stockley RA. Radiologic and clinical features of COPD patients with discordant pulmonary physiology: lessons from alpha1-antitrypsin deficiency. Chest. 2007;132(3):909-915.
    • (2007) Chest , vol.132 , Issue.3 , pp. 909-915
    • Holme, J.1    Stockley, R.A.2
  • 27
    • 84874708546 scopus 로고    scopus 로고
    • Age related development of respiratory abnormalities in non-index α-1 antitrypsin deficient studies
    • Holme J, Stockley JA, Stockley RA. Age related development of respiratory abnormalities in non-index α-1 antitrypsin deficient studies. Respir Med. 2013;107(3):387-393.
    • (2013) Respir Med , vol.107 , Issue.3 , pp. 387-393
    • Holme, J.1    Stockley, J.A.2    Stockley, R.A.3
  • 28
    • 0032110436 scopus 로고    scopus 로고
    • Survival and FEV1 decline in individuals with severe deficiency of alpha1-antitrypsin
    • The Alpha-1-Antitrypsin Deficiency Registry Study Group
    • Survival and FEV1 decline in individuals with severe deficiency of alpha1-antitrypsin. The Alpha-1-Antitrypsin Deficiency Registry Study Group. Am J Respir Crit Care Med. 1998;158(1):49-59.
    • (1998) Am J Respir Crit Care Med , vol.158 , Issue.1 , pp. 49-59
  • 29
    • 0031242842 scopus 로고    scopus 로고
    • Does alpha1-antitrypsin augmentation therapy slow the annual decline in FEV1 in patients with severe hereditary alpha1-antitrypsin deficiency?
    • Wissenschaftliche Arbeitsgemeinschaft zur Therapie von Lungenerkrankungen (WATL) alpha1-AT study group
    • Seersholm N, Wencker M, Banik N, et al. Does alpha1-antitrypsin augmentation therapy slow the annual decline in FEV1 in patients with severe hereditary alpha1-antitrypsin deficiency? Wissenschaftliche Arbeitsgemeinschaft zur Therapie von Lungenerkrankungen (WATL) alpha1-AT study group. Eur Respir J. 1997;10(10):2260-2263.
    • (1997) Eur Respir J , vol.10 , Issue.10 , pp. 2260-2263
    • Seersholm, N.1    Wencker, M.2    Banik, N.3
  • 30
    • 0035095548 scopus 로고    scopus 로고
    • Wissenschaftliche Arbeitsgemeinschaft zur Therapie von Lungenerkrankungen. Longitudinal follow-up of patients with alpha(1)-protease inhibitor deficiency before and during therapy with IV alpha(1)-protease inhibitor
    • Wencker M, Fuhrmann B, Banik N, Konietzko N; Wissenschaftliche Arbeitsgemeinschaft zur Therapie von Lungenerkrankungen. Longitudinal follow-up of patients with alpha(1)-protease inhibitor deficiency before and during therapy with IV alpha(1)-protease inhibitor. Chest. 2001;119(3):737-744.
    • (2001) Chest , vol.119 , Issue.3 , pp. 737-744
    • Wencker, M.1    Fuhrmann, B.2    Banik, N.3    Konietzko, N.4
  • 31
    • 70350450961 scopus 로고    scopus 로고
    • Augmentation therapy for alpha1 antitrypsin deficiency: A meta-analysis
    • Chapman KR, Stockley RA, Dawkins C, Wilkes MM, Navickis RJ. Augmentation therapy for alpha1 antitrypsin deficiency: a meta-analysis. COPD. 2009;6(3):177-184.
    • (2009) COPD , vol.6 , Issue.3 , pp. 177-184
    • Chapman, K.R.1    Stockley, R.A.2    Dawkins, C.3    Wilkes, M.M.4    Navickis, R.J.5
  • 32
    • 0032724157 scopus 로고    scopus 로고
    • A randomized clinical trial of alpha(1)-antitrypsin augmentation therapy
    • Dirksen A, Dijkman JH, Madsen F, et al. A randomized clinical trial of alpha(1)-antitrypsin augmentation therapy. Am J Respir Crit Care Med. 1999;160(5 pt 1):1468-1472.
    • (1999) Am J Respir Crit Care Med , vol.160 , Issue.5 PART 1 , pp. 1468-1472
    • Dirksen, A.1    Dijkman, J.H.2    Madsen, F.3
  • 33
    • 42949110370 scopus 로고    scopus 로고
    • Detection of emphysema progression in alpha 1-antitrypsin deficiency using CT densitometry; methodological advances
    • Parr DG, Sevenoaks M, Deng C, Stoel BC, Stockley RA. Detection of emphysema progression in alpha 1-antitrypsin deficiency using CT densitometry; methodological advances. Respir Res. 2008;9(1):21.
    • (2008) Respir Res , vol.9 , Issue.1 , pp. 21
    • Parr, D.G.1    Sevenoaks, M.2    Deng, C.3    Stoel, B.C.4    Stockley, R.A.5
  • 34
    • 5144232755 scopus 로고    scopus 로고
    • Influence of calibration on densitometric studies of emphysema progression using computed tomography
    • Parr DG, Stoel BC, Stolk J, Nightingale PG, Stockley RA. Influence of calibration on densitometric studies of emphysema progression using computed tomography. Am J Respir Crit Care Med. 2004;170(8):883-890.
    • (2004) Am J Respir Crit Care Med , vol.170 , Issue.8 , pp. 883-890
    • Parr, D.G.1    Stoel, B.C.2    Stolk, J.3    Nightingale, P.G.4    Stockley, R.A.5
  • 35
    • 78649455530 scopus 로고    scopus 로고
    • Exploring the optimum approach to the use of CT densitometry in a randomised placebo-controlled study of augmentation therapy in alpha 1-antitrypsin deficiency
    • Parr DG, Dirksen A, Piitulainen E, Deng C, Wencker M, Stockley RA. Exploring the optimum approach to the use of CT densitometry in a randomised placebo-controlled study of augmentation therapy in alpha 1-antitrypsin deficiency. Respir Res. 2009;10(75):75.
    • (2009) Respir Res , vol.10 , Issue.75 , pp. 75
    • Parr, D.G.1    Dirksen, A.2    Piitulainen, E.3    Deng, C.4    Wencker, M.5    Stockley, R.A.6
  • 36
    • 77957273246 scopus 로고    scopus 로고
    • Therapeutic efficacy of α-1 antitrypsin augmentation therapy on the loss of lung tissue: An integrated analysis of 2 randomised clinical trials using computed tomography densitometry
    • Stockley RA, Parr DG, Piitulainen E, Stolk J, Stoel BC, Dirksen A. Therapeutic efficacy of α-1 antitrypsin augmentation therapy on the loss of lung tissue: an integrated analysis of 2 randomised clinical trials using computed tomography densitometry. Respir Res. 2010;11:136.
    • (2010) Respir Res , vol.11 , pp. 136
    • Stockley, R.A.1    Parr, D.G.2    Piitulainen, E.3    Stolk, J.4    Stoel, B.C.5    Dirksen, A.6
  • 37
    • 84880712208 scopus 로고    scopus 로고
    • IV alpha antitrypsin (A1AT) preserves lung density in homozygous alpha-1-antitrypsin deficiency (A1ATD): A randomized placebocontrolled trial
    • Chapman KR, Burdon JGW, Piitulainen E et al. IV alpha antitrypsin (A1AT) preserves lung density in homozygous alpha-1-antitrypsin deficiency (A1ATD): a randomized placebocontrolled trial. Am J Resp Crit Care Med. 2013;187:A6069.
    • (2013) Am J Resp Crit Care Med , vol.187
    • Chapman, K.R.1    Burdon, J.G.W.2    Piitulainen, E.3
  • 38
    • 46949107890 scopus 로고    scopus 로고
    • Polymers and inflammation: Disease mechanisms of the serpinopathies
    • Gooptu B, Lomas DA. Polymers and inflammation: disease mechanisms of the serpinopathies. J Exp Med. 2008;205(7):1529-1534.
    • (2008) J Exp Med , vol.205 , Issue.7 , pp. 1529-1534
    • Gooptu, B.1    Lomas, D.A.2
  • 39
    • 84875678375 scopus 로고    scopus 로고
    • Liver disease in alpha-1 antitrypsin deficiency: Current understanding and future therapy
    • Teckman JH. Liver disease in alpha-1 antitrypsin deficiency: current understanding and future therapy. COPD. 2013;10(10 suppl 1):35-43.
    • (2013) COPD , vol.10 , Issue.10 SUPPL. 1 , pp. 35-43
    • Teckman, J.H.1
  • 40
    • 0034652248 scopus 로고    scopus 로고
    • Chemical chaperones mediate increased secretion of mutant alpha 1-antitrypsin (alpha 1-AT) Z: A potential pharmacological strategy for prevention of liver injury and emphysema in alpha 1-AT deficiency
    • Burrows JA, Willis LK, Perlmutter DH. Chemical chaperones mediate increased secretion of mutant alpha 1-antitrypsin (alpha 1-AT) Z: a potential pharmacological strategy for prevention of liver injury and emphysema in alpha 1-AT deficiency. Proc Natl Acad Sci U S A. 2000;97(4):1796-1801.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , Issue.4 , pp. 1796-1801
    • Burrows, J.A.1    Willis, L.K.2    Perlmutter, D.H.3
  • 41
    • 84890268113 scopus 로고
    • Properties of mutant forms of alphaproteinase inhibitor prepared by recombinant DNA technology
    • Taylor JC, Mittman C, eds. Orlando, FL: Academic Press
    • Travis J, Matheson NR. Properties of mutant forms of alphaproteinase inhibitor prepared by recombinant DNA technology. In: Taylor JC, Mittman C, eds. Pulmonary Emphysema and Proteolysis. Orlando, FL: Academic Press;1986:133-141.
    • (1986) Pulmonary Emphysema and Proteolysis , pp. 133-141
    • Travis, J.1    Matheson, N.R.2
  • 42
    • 0020510606 scopus 로고
    • Mutation of antitrypsin to antithrombin. Alpha 1-antitrypsin Pittsburgh (358 Met leads to Arg), a fatal bleeding disorder
    • Owen MC, Brennan SO, Lewis JH, Carrell RW. Mutation of antitrypsin to antithrombin. alpha 1-antitrypsin Pittsburgh (358 Met leads to Arg), a fatal bleeding disorder. N Engl J Med. 1983;309(12):694-698.
    • (1983) N Engl J Med , vol.309 , Issue.12 , pp. 694-698
    • Owen, M.C.1    Brennan, S.O.2    Lewis, J.H.3    Carrell, R.W.4
  • 43
    • 0018800894 scopus 로고
    • The oxidative inactivation of human alpha-1-proteinase inhibitor. Further evidence for methionine at the reactive center
    • Johnson D, Travis J. The oxidative inactivation of human alpha-1-proteinase inhibitor. Further evidence for methionine at the reactive center. J Biol Chem. 1979;254(10):4022-4026.
    • (1979) J Biol Chem , vol.254 , Issue.10 , pp. 4022-4026
    • Johnson, D.1    Travis, J.2
  • 44
    • 0018611004 scopus 로고
    • Cigarette smoking induces functional antiprotease deficiency in the lower respiratory tract of humans
    • Gadek JE, Fells GA, Crystal RG. Cigarette smoking induces functional antiprotease deficiency in the lower respiratory tract of humans. Science. 1979;206(4424):1315-1316.
    • (1979) Science , vol.206 , Issue.4424 , pp. 1315-1316
    • Gadek, J.E.1    Fells, G.A.2    Crystal, R.G.3
  • 45
    • 0000518899 scopus 로고
    • Potential mechanism of emphysema: A 1-proteinase inhibitor recovered from lungs of cigarette smokers contains oxidized methionine and has decreased elastase inhibitory capacity
    • Carp H, Miller F, Hoidal JR, Janoff A. Potential mechanism of emphysema: a 1-proteinase inhibitor recovered from lungs of cigarette smokers contains oxidized methionine and has decreased elastase inhibitory capacity. Proc Natl Acad Sci U S A. 1982;79(6):2041-2045.
    • (1982) Proc Natl Acad Sci U S A , vol.79 , Issue.6 , pp. 2041-2045
    • Carp, H.1    Miller, F.2    Hoidal, J.R.3    Janoff, A.4
  • 46
    • 0020616229 scopus 로고
    • Functional alpha 1-protease inhibitor in the lower respiratory tract of cigarette smokers is not decreased
    • Stone PJ, Calore JD, McGowan SE, Bernardo J, Snider GL, Franzblau C. Functional alpha 1-protease inhibitor in the lower respiratory tract of cigarette smokers is not decreased. Science. 1983;221(4616):1187-1189.
    • (1983) Science , vol.221 , Issue.4616 , pp. 1187-1189
    • Stone, P.J.1    Calore, J.D.2    McGowan, S.E.3    Bernardo, J.4    Snider, G.L.5    Franzblau, C.6
  • 47
    • 0023268064 scopus 로고
    • The elastase inhibitory capacity and the alpha 1-proteinase inhibitor and bronchial inhibitor content of bronchoalveolar lavage fluids from healthy subjects
    • Boudier C, Pelletier A, Gast A, Tournier JM, Pauli G, Bieth JG. The elastase inhibitory capacity and the alpha 1-proteinase inhibitor and bronchial inhibitor content of bronchoalveolar lavage fluids from healthy subjects. Biol Chem Hoppe Seyler. 1987;368(8):981-990.
    • (1987) Biol Chem Hoppe Seyler , vol.368 , Issue.8 , pp. 981-990
    • Boudier, C.1    Pelletier, A.2    Gast, A.3    Tournier, J.M.4    Pauli, G.5    Bieth, J.G.6
  • 48
    • 0023739849 scopus 로고
    • The assessment of a 1 proteinase inhibitor form and function in lung lavage fluid from healthy subjects
    • Afford SC, Burnett D, Campbell EJ, Cury JD, Stockley RA. The assessment of a 1 proteinase inhibitor form and function in lung lavage fluid from healthy subjects. Biol Chem Hoppe Seyler. 1988;369(9):1065-1074.
    • (1988) Biol Chem Hoppe Seyler , vol.369 , Issue.9 , pp. 1065-1074
    • Afford, S.C.1    Burnett, D.2    Campbell, E.J.3    Cury, J.D.4    Stockley, R.A.5
  • 49
    • 0022714498 scopus 로고
    • The effect of catalase and methionine-S-oxide reductase on oxidised alpha 1-proteinase inhibitor
    • Morrison HM, Burnett D, Stockley RA. The effect of catalase and methionine-S-oxide reductase on oxidised alpha 1-proteinase inhibitor. Biol Chem Hoppe Seyler. 1986;367(5):371-378.
    • (1986) Biol Chem Hoppe Seyler , vol.367 , Issue.5 , pp. 371-378
    • Morrison, H.M.1    Burnett, D.2    Stockley, R.A.3
  • 51
    • 0023147734 scopus 로고
    • 1-proteinase inhibitor deficiency or chronic obstructive bronchitis: Anti-elastase function and cell profile
    • 1-proteinase inhibitor deficiency or chronic obstructive bronchitis: anti-elastase function and cell profile. Clin Sci (Lond). 1987;72(3):373-381.
    • (1987) Clin Sci (Lond) , vol.72 , Issue.3 , pp. 373-381
    • Morrison, H.M.1    Kramps, J.A.2    Burnett, D.3    Stockley, R.A.4
  • 53
    • 14044269009 scopus 로고    scopus 로고
    • The role of oxidative stress in chronic obstructive pulmonary disease
    • Bowler RP, Barnes PJ, Crapo JD. The role of oxidative stress in chronic obstructive pulmonary disease. COPD. 2004;1(2):255-277.
    • (2004) COPD , vol.1 , Issue.2 , pp. 255-277
    • Bowler, R.P.1    Barnes, P.J.2    Crapo, J.D.3
  • 54
    • 0031961853 scopus 로고    scopus 로고
    • Oscillatory pericellular proteolysis and oxidant deposition during neutrophil locomotion
    • Kindzelskii AL, Zhou MJ, Haugland RP, Boxer LA, Petty HR. Oscillatory pericellular proteolysis and oxidant deposition during neutrophil locomotion. Biophys J. 1998;74(1):90-97.
    • (1998) Biophys J , vol.74 , Issue.1 , pp. 90-97
    • Kindzelskii, A.L.1    Zhou, M.J.2    Haugland, R.P.3    Boxer, L.A.4    Petty, H.R.5
  • 55
    • 0024239623 scopus 로고
    • Proteinase 3. A distinct human polymorphonuclear leukocyte proteinase that produces emphysema in hamsters
    • Kao RC, Wehner NG, Skubitz KM, Gray BH, Hoidal JR. Proteinase 3. A distinct human polymorphonuclear leukocyte proteinase that produces emphysema in hamsters. J Clin Invest. 1988;82(6):1963-1973.
    • (1988) J Clin Invest , vol.82 , Issue.6 , pp. 1963-1973
    • Kao, R.C.1    Wehner, N.G.2    Skubitz, K.M.3    Gray, B.H.4    Hoidal, J.R.5
  • 56
    • 0025780051 scopus 로고
    • Marked longevity of human lung parenchymal elastic fibers deduced from prevalence of D-aspartate and nuclear weapons-related radiocarbon
    • Shapiro SD, Endicott SK, Province MA, Pierce JA, Campbell EJ. Marked longevity of human lung parenchymal elastic fibers deduced from prevalence of D-aspartate and nuclear weapons-related radiocarbon. J Clin Invest. 1991;87(5):1828-1834.
    • (1991) J Clin Invest , vol.87 , Issue.5 , pp. 1828-1834
    • Shapiro, S.D.1    Endicott, S.K.2    Province, M.A.3    Pierce, J.A.4    Campbell, E.J.5
  • 57
    • 0029006923 scopus 로고
    • Double pylorus: Report of a longitudinal follow-up in two refractory cases with underlying diseases
    • Hu TH, Tai DI, Changchien CS, Chen TY, Chang WC. Double pylorus: report of a longitudinal follow-up in two refractory cases with underlying diseases. Am J Gastroenterol. 1995;90(5):815-818.
    • (1995) Am J Gastroenterol , vol.90 , Issue.5 , pp. 815-818
    • Hu, T.H.1    Tai, D.I.2    Changchien, C.S.3    Chen, T.Y.4    Chang, W.C.5
  • 58
    • 0017127862 scopus 로고
    • The induction of emphysema with elastase. II. Changes in connective tissue
    • Kuhn C, Yu SY, Chraplyvy M, Linder HE, Senior RM. The induction of emphysema with elastase. II. Changes in connective tissue. Lab Invest. 1976;34(4):372-380.
    • (1976) Lab Invest , vol.34 , Issue.4 , pp. 372-380
    • Kuhn, C.1    Yu, S.Y.2    Chraplyvy, M.3    Linder, H.E.4    Senior, R.M.5
  • 59
    • 0020617580 scopus 로고
    • Changes in connective tissue composition of the lung in starvation and refeeding
    • Sahebjami H, MacGee J. Changes in connective tissue composition of the lung in starvation and refeeding. Am Rev Respir Dis. 1983;128(4):644-647.
    • (1983) Am Rev Respir Dis , vol.128 , Issue.4 , pp. 644-647
    • Sahebjami, H.1    MacGee, J.2
  • 60
    • 0019055958 scopus 로고
    • The effect of lathyrogens on the evolution of elastase-induced emphysema
    • Kuhn C III, Starcher BC. The effect of lathyrogens on the evolution of elastase-induced emphysema. Am Rev Respir Dis. 1980;122(3):453-460.
    • (1980) Am Rev Respir Dis , vol.122 , Issue.3 , pp. 453-460
    • Kuhn III, C.1    Starcher, B.C.2
  • 61
    • 0026578548 scopus 로고
    • Induction of emphysema in hamsters by intratracheal instillation of cathepsin B
    • Lesser M, Padilla ML, Cardozo C. Induction of emphysema in hamsters by intratracheal instillation of cathepsin B. Am Rev Respir Dis. 1992;145(3):661-668.
    • (1992) Am Rev Respir Dis , vol.145 , Issue.3 , pp. 661-668
    • Lesser, M.1    Padilla, M.L.2    Cardozo, C.3
  • 62
    • 0022500794 scopus 로고
    • Immunolocalization of elastase in human emphysematous lungs
    • Damiano VV, Tsang A, Kucich U, et al. Immunolocalization of elastase in human emphysematous lungs. J Clin Invest. 1986;78(2):482-493.
    • (1986) J Clin Invest , vol.78 , Issue.2 , pp. 482-493
    • Damiano, V.V.1    Tsang, A.2    Kucich, U.3
  • 63
    • 0034606218 scopus 로고    scopus 로고
    • Interferon gamma induction of pulmonary emphysema in the adult murine lung
    • Wang Z, Zheng T, Zhu Z, et al. Interferon gamma induction of pulmonary emphysema in the adult murine lung. J Exp Med. 2000;192(11):1587-1600.
    • (2000) J Exp Med , vol.192 , Issue.11 , pp. 1587-1600
    • Wang, Z.1    Zheng, T.2    Zhu, Z.3
  • 64
    • 0030823772 scopus 로고    scopus 로고
    • Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice
    • Hautamaki RD, Kobayashi DK, Senior RM, Shapiro SD. Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice. Science. 1997;277(5334):2002-2004.
    • (1997) Science , vol.277 , Issue.5334 , pp. 2002-2004
    • Hautamaki, R.D.1    Kobayashi, D.K.2    Senior, R.M.3    Shapiro, S.D.4
  • 66
    • 14044272775 scopus 로고    scopus 로고
    • Proteases and emphysema
    • Churg A, Wright JL. Proteases and emphysema. Curr Opin Pulm Med. 2005;11(2):153-159.
    • (2005) Curr Opin Pulm Med , vol.11 , Issue.2 , pp. 153-159
    • Churg, A.1    Wright, J.L.2
  • 67
    • 47849105932 scopus 로고    scopus 로고
    • Roles for proteinases in the pathogenesis of chronic obstructive pulmonary disease
    • Owen CA. Roles for proteinases in the pathogenesis of chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis. 2008;3(2):253-268.
    • (2008) Int J Chron Obstruct Pulmon Dis , vol.3 , Issue.2 , pp. 253-268
    • Owen, C.A.1
  • 68
    • 0023264892 scopus 로고
    • Neutrophils from subjects with chronic obstructive lung disease show enhanced chemotaxis and extracellular proteolysis
    • Burnett D, Chamba A, Hill SL, Stockley RA. Neutrophils from subjects with chronic obstructive lung disease show enhanced chemotaxis and extracellular proteolysis. Lancet. 1987;2(8567):1043-1046.
    • (1987) Lancet , vol.2 , Issue.8567 , pp. 1043-1046
    • Burnett, D.1    Chamba, A.2    Hill, S.L.3    Stockley, R.A.4
  • 69
    • 17244383539 scopus 로고    scopus 로고
    • Endothelial interactions of neutrophils under flow in chronic obstructive pulmonary disease
    • Woolhouse IS, Bayley DL, Lalor P, Adams DH, Stockley RA. Endothelial interactions of neutrophils under flow in chronic obstructive pulmonary disease. Eur Respir J. 2005;25(4):612-617.
    • (2005) Eur Respir J , vol.25 , Issue.4 , pp. 612-617
    • Woolhouse, I.S.1    Bayley, D.L.2    Lalor, P.3    Adams, D.H.4    Stockley, R.A.5
  • 70
    • 79955487961 scopus 로고    scopus 로고
    • Behavioral and structural differences in migrating peripheral neutrophils from patients with chronic obstructive pulmonary disease
    • Sapey E, Stockley JA, Greenwood H, et al. Behavioral and structural differences in migrating peripheral neutrophils from patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2011;183(9):1176-1186.
    • (2011) Am J Respir Crit Care Med , vol.183 , Issue.9 , pp. 1176-1186
    • Sapey, E.1    Stockley, J.A.2    Greenwood, H.3
  • 72
    • 84870454294 scopus 로고    scopus 로고
    • Assessment of pulmonary neutrophilic inflam mation in emphysema by quantitative positron emission tomography
    • Subramanian DR, Jenkins L, Edgar R, Quraishi N, Stockley RA, Parr DG. Assessment of pulmonary neutrophilic inflam mation in emphysema by quantitative positron emission tomography. Am J Respir Crit Care Med. 2012;186(11):1125-1132.
    • (2012) Am J Respir Crit Care Med , vol.186 , Issue.11 , pp. 1125-1132
    • Subramanian, D.R.1    Jenkins, L.2    Edgar, R.3    Quraishi, N.4    Stockley, R.A.5    Parr, D.G.6
  • 73
    • 0032743423 scopus 로고    scopus 로고
    • Quantum proteolysis by neutrophils: Implications for pulmonary emphysema in alpha 1-antitrypsin deficiency
    • Campbell EJ, Campbell MA, Boukedes SS, Owen CA. Quantum proteolysis by neutrophils: implications for pulmonary emphysema in alpha 1-antitrypsin deficiency. J Clin Invest. 1999;104(3):337-344.
    • (1999) J Clin Invest , vol.104 , Issue.3 , pp. 337-344
    • Campbell, E.J.1    Campbell, M.A.2    Boukedes, S.S.3    Owen, C.A.4
  • 74
    • 84855397703 scopus 로고    scopus 로고
    • Series "matrix metalloproteinases in lung health and disease": Matrix metalloproteinases in COPD
    • Churg A, Zhou S, Wright JL. Series "matrix metalloproteinases in lung health and disease": matrix metalloproteinases in COPD. Eur Respir J. 2012;39(1):197-209.
    • (2012) Eur Respir J , vol.39 , Issue.1 , pp. 197-209
    • Churg, A.1    Zhou, S.2    Wright, J.L.3
  • 75
    • 84874098071 scopus 로고    scopus 로고
    • The rapid FEV(1) decline in chronic obstructive pulmonary disease is associated with predominant emphysema: A longitudinal study
    • Cerveri I, Corsico AG, Grosso A, et al. The rapid FEV(1) decline in chronic obstructive pulmonary disease is associated with predominant emphysema: a longitudinal study. COPD. 2013;10(1):55-61.
    • (2013) COPD , vol.10 , Issue.1 , pp. 55-61
    • Cerveri, I.1    Corsico, A.G.2    Grosso, A.3
  • 76
    • 77956849832 scopus 로고    scopus 로고
    • CT scan findings of emphysema predict mortality in COPD
    • Haruna A, Muro S, Nakano Y, et al. CT scan findings of emphysema predict mortality in COPD. Chest. 2010;138(3):635-640.
    • (2010) Chest , vol.138 , Issue.3 , pp. 635-640
    • Haruna, A.1    Muro, S.2    Nakano, Y.3
  • 77
    • 84857229152 scopus 로고    scopus 로고
    • Association of IREB2 and CHRNA3 polymorphisms with airflow obstruction in severe alpha-1 antitrypsin deficiency
    • Kim WJ, Wood AM, Barker AF, et al. Association of IREB2 and CHRNA3 polymorphisms with airflow obstruction in severe alpha-1 antitrypsin deficiency. Respir Res. 2012;13:16.
    • (2012) Respir Res , vol.13 , pp. 16
    • Kim, W.J.1    Wood, A.M.2    Barker, A.F.3
  • 78
    • 77956620618 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha rs361525 polymorphism is associated with increased local production and downstream inflammation in COPD
    • 15
    • Sapey E, Wood AM, Ahmad A, Stockley RA. Tumor necrosis factor alpha rs361525 polymorphism is associated with increased local production and downstream inflammation in COPD. Am J Respir Crit Care Med, 2010;15:182(2):192- 199.
    • (2010) Am J Respir Crit Care Med , vol.182 , Issue.2 , pp. 192-199
    • Sapey, E.1    Wood, A.M.2    Ahmad, A.3    Stockley, R.A.4
  • 79
    • 63049100304 scopus 로고    scopus 로고
    • Matrix metalloprotease polymorphisms are associated with gas transfer in alpha 1 antitrypsin deficiency
    • McAloon CJ, Wood AM, Gough SC, Stockley RA. Matrix metalloprotease polymorphisms are associated with gas transfer in alpha 1 antitrypsin deficiency. Ther Adv Respir Dis. 2009;3(1):23-30.
    • (2009) Ther Adv Respir Dis , vol.3 , Issue.1 , pp. 23-30
    • McAloon, C.J.1    Wood, A.M.2    Gough, S.C.3    Stockley, R.A.4
  • 80
    • 37549041728 scopus 로고    scopus 로고
    • IL10 polymorphisms are associated with airflow obstruction in severe alpha1-antitrypsin deficiency
    • Demeo DL, Campbell EJ, Barker AF, et al. IL10 polymorphisms are associated with airflow obstruction in severe alpha1-antitrypsin deficiency. Am J Respir Cell Mol Biol. 2008;38(1):114-120.
    • (2008) Am J Respir Cell Mol Biol , vol.38 , Issue.1 , pp. 114-120
    • Demeo, D.L.1    Campbell, E.J.2    Barker, A.F.3
  • 81
    • 84865214922 scopus 로고    scopus 로고
    • Expanding the clinical indications for α(1)-antitrypsin therapy
    • Lewis EC. Expanding the clinical indications for α(1)-antitrypsin therapy. Mol Med. 2012;18:957-970.
    • (2012) Mol Med , vol.18 , pp. 957-970
    • Lewis, E.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.