Cytoplasmic p21CIP1/WAF1, ERK1/2 activation, and cytoskeletal remodeling are associated with the senescence-like phenotype after airborne particulate matter (PM10) exposure in lung cells

Toxicology Letters

Volumn 225, Issue 1, 2014, Pages 12-19

  Sánchez Pérez, Yesennia ^a   Chirino, Yolanda I ^b   Osornio Vargas, Álvaro Román ^c   Herrera, Luis A ^d   Morales Bárcenas, Rocío ^a   López Saavedra, Alejandro ^a   González Ramírez, Imelda ^a   Miranda, Javier ^d   García Cuellar, Claudia María ^a  

^a INSTITUTO NACIONAL DE CANCEROLOGÍA   (Mexico)

^b UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^c UNIVERSITY OF ALBERTA   (Canada)

^d UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

Cytoskeleton remodeling; P21CIP1 WAF1 cytoplasmic; Particulate matter; PM10; Senescence like

Indexed keywords

BETA GALACTOSIDASE; CYCLIN DEPENDENT KINASE INHIBITOR 1; F ACTIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHALLOIDIN;

AIRBORNE PARTICLE; APOPTOSIS; ARTICLE; CARCINOGENIC ACTIVITY; CELL AGING; CELL CYCLE ARREST; CELL CYCLE PHASE; CELL VIABILITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; CYTOSKELETON; CYTOTOXICITY; HUMAN; HUMAN CELL; LUNG ADENOCARCINOMA; LUNG ALVEOLUS CELL; PARTICULATE MATTER; PHOSPHORYLATION; PRIORITY JOURNAL; STRESS FIBER; WESTERN BLOTTING;

CYTOSKELETON REMODELING; P21(CIP1/WAF1) CYTOPLASMIC; PARTICULATE MATTER; PM(10); SENESCENCE-LIKE;

ACTINS; BETA-GALACTOSIDASE; CELL AGING; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYTOPLASM; CYTOSKELETON; ENZYME ACTIVATION; HUMANS; LUNG; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PARTICLE SIZE; PARTICULATE MATTER; PHENOTYPE; PHOSPHORYLATION; SIGNAL TRANSDUCTION; STRESS FIBERS; TIME FACTORS;

EID: 84890249151     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2013.11.018     Document Type: Article

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